Biography

I, Dr. Ramachandra is presently working as Lecturer in Chemistry Government College for Men, kadapa, India. I completed Ph.D. in Chemistry from Jawaharlal Nehru Technological University, Hyderabad, India. I pursued M.Sc., in Analytical Chemistry at S.K. University Campus, Anantapur, Andhra Pradesh. My research interests are Impurity Profiling of Drugs and Pharmaceuticals, Isolation and characterization of Impurities in drugs and Pharmaceuticals by HPLC, NMR and Mass Spectrometry, Stability studies and Degradation studies, Applications of Ionic Liquids in Chromatographic separation, Chiral shift Reagents for separation of Enantiomers by NMR Spectroscopy, and method development and validation of Drugs and Pharmaceuticals. I have published 15 research articles in international peer reviewed journals.

Area of Interest:

Chemistry

100%

Molecularly Imprinted Polymers

62%

Electrochemical Sensors

90%

Ionic Liquids

75%

Chiral Shift Reagents

55%

Research Publications in Numbers

Books
1

Chapters
3

Articles
17

Abstracts
5

Selected Publications

Challa G.N., N.V. Nimmu, R. Bondigalla and M.S. Arnipalli, 2020. Bioassay studies of risperidone and its active metabolite in rat dried blood spots and dried plasma spots using lc‐esi‐ms/ms: comparison of their pharmacokinetic profiles. SEPARATION SCIENCE PLUS 10.1002/sscp.202000021 http://dx.doi.org/10.1002/sscp.202000021.
CrossRef |
Kumar, N.S., V. Sreenivasulu, B. Ramachandra, M. Asif and A.A. Ibrahim, 2018. A stability-indicating LC-MS method for determination of perindopril and its process related impurities. Pharmaceut. Chem. J., 52: 378-383.
CrossRef | Direct Link |
Ramisetti, N.R., M.S. Arnipalli, N.V. Nimmu and R. Bondigalla, 2017. UHPLC determination of besifloxacin enantiomers on immobilized amylose tris(3,5-dichlorophenylcarbamate) chiral stationary phase. Chromatographia, 80: 1509-1515.
CrossRef | Direct Link |
Ramachandra, B., 2017. Development of impurity profiling methods using modern analytical techniques. Crit. Rev. Anal. Chem., 47: 24-36.
CrossRef | Direct Link |
Rao, R.N. and B. Ramachandra, 2016. Ionic liquids in monolithic LC separations- ILs as mobilephase additives in separation of antiretrovirals. G.I.T. Lab. J., .
Ramachandra, B., 2016. Enantiomeric discrimination and quantification of zolmitriptan by 1H NMR spectroscopy using (R)-(-)-a-Methoxy phenyl acetic acid as chiral solvating agent. J. Chem. Pharm. Res., 8: 56-65.
Ramachandra, B., 2016. A critical review of properties of modafinil and analytical, bioanalytical methods for its determination. Crit. Rev. Anal. Chem., 46: 482-489.
CrossRef | Direct Link |
Rao, R.N., B. Ramachandra, B. Sravan and S. Khalid, 2014. LC-MS/MS characterization of degradation products of darunavir: an anti HIV drug. J. Pharm. Biomed. Anal., 89: 23-33.
Rao, R.N., B. Ramachandra and K. Santhakumar, 2013. RP-HPLC separation and characterization of unknown impurities of a novel HIV-protease inhibitor Darunavir by ESI-MS and 2D NMR spectroscopy. J. Pharm. Biomed. Anal., 75: 186-191.
CrossRef |
Rao, R.N., B. Ramachandra and K. Santhakumar, 2012. Evaluation of (R)-(-)-α-methoxy phenyl acetic acid as a chiral shift reagent for resolution and determination of R and S enantiomers of modafinil in bulk drugs and formulations by 1H NMR spectroscopy. Chirality, 24: 339-344.
Direct Link |
Rao, R.N., R.M. Vali, B. Ramachandra and S.S. Raju, 2011. Separation and characterization of forced degradation products of abacavir sulphate by LC-MS/MS. J. Pharm. Biomed. Anal., 54: 279-285.
CrossRef | Direct Link |
Rao, R.N., R.M. Vali, B. Ramachandra and P.K. Maurya, 2011. Rapid determination of rifaximin on dried blood spots by LC‐ESI‐MS. Biomed. Chromatogr., 25: 1201-1207.
CrossRef | Direct Link |
Rao, R.N., B. Ramachandra and R.M. Vail, 2011. Reversed-phase liquid chromatographic separation of antiretroviral drugs on a monolithic column using ionic liquids as mobile phase additives. J. Separation Sci., 34: 500-507.
CrossRef |
Rao, R.N., B. Ramachandra, R.M. Vali and S.S. Raju, 2010. LC-MS/MS studies of ritonavir and its forced degradation products. J. Pharm. Biomed. Anal., 53: 833-842.
CrossRef | Direct Link |