Area of Interest:

Molecular Sciences

100%

Epigenetics

62%

Histone Modifications

90%

Microarray

75%

Diabetes

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
0

Abstracts
0

Selected Publications

Dhawan, D. and J. Gupta, 2017. Comparison of different solvents for phytochemical extraction potential from Datura metel plant leaves. Int. J. Biol. Chem., 11: 17-22.
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Karpe, P.A., J. Gupta, R.F. Marthong, P. Ramarao and K. Tikoo, 2012. Insulin resistance induces a segmental difference in thoracic and abdominal aorta: Differential expression of AT1 and AT2 receptors. J. Hypertens., 30: 132-146.
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Gupta, J., S. Kumar, J. Li, R.K.M. Karuturi and K. Tikoo, 2012. Histone H3 lysine 4 monomethylation (H3K4me1) and H3 lysine 9 monomethylation (H3K9me1): Distribution and their association in regulating gene expression under hyperglycaemic/hyperinsulinemic conditions in 3T3 cells. Biochimie, 94: 2656-2664.
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Gupta, J. and K. Tikoo, 2012. Involvement of insulin-induced reversible chromatin remodeling in altering the expression of oxidative stress-responsive genes under hyperglycemia in 3T3-L1 preadipocytes. Gene, 504: 181-191.
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Surse, V.M., J. Gupta and K. Tikoo, 2011. Esculetin induced changes in Mmp13 and Bmp6 gene expression and histone H3 modifications attenuate development of glomerulosclerosis in diabetic rats. J. Mol. Endocrinol., 46: 245-254.
PubMed |
Gupta, J., A.B. Gaikwad and K. Tikoo, 2010. Hepatic expression profiling shows involvement of PKC epsilon, DGK eta, Tnfaip and Rho kinase in type 2 diabetic nephropathy rats. J. Cell. Biochem., 111: 944-954.
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Gaikwad, A.B., J. Gupta and K. Tikoo, 2010. Epigenetic changes and alteration of Fbn1 and Col3A1 gene expression under hyperglycaemic and hyperinsulinaemic conditions. Biochem. J., 432: 333-341.
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Tikoo, K., P. Kumar and J. Gupta, 2009. Rosiglitazone synergizes anticancer activity of cisplatin and reduces its nephrotoxicity in 7, 12-dimethyl benz{a}anthracene (DMBA) induced breast cancer rats. BMC Cancer, Vol. 9. 10.1186/1471-2407-9-107.
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Tikoo, K., I.Y. Ali, J. Gupta and C. Gupta, 2009. 5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats. Toxicol. Lett., 191: 158-166.
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Kabra, D.G., J. Gupta and K. Tikoo, 2009. Insulin induced alteration in post-translational modifications of histone H3 under a hyperglycemic condition in L6 skeletal muscle myoblasts. Biochim. Biophys. Acta, Mol. Basis Dis., 1792: 574-583.
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Tikoo, K., A. Tamta, I.Y. Ali, J. Gupta and A.B. Gaikwad, 2008. Tannic acid prevents azidothymidine (AZT) induced hepatotoxicity and genotoxicity along with change in expression of PARG and histone H3 acetylation. Toxicol. Lett., 177: 90-96.
PubMed |