Dr. Sangita Singh
Post-doctoral FellowUNC School of Medicine, USA
Highest Degree
Ph.D. in Biochemistry from University of Nebraska-Lincoln, USA
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UNC School of Medicine, USA
Biography
Dr. Sangita Singh is currently working as Principal Investigator at DuPont Knowledge Center, Shamir pet, Hyderabad, Andhra Pradesh, India. She has completed her PhD in Biotechnology, University of Nebraska, Lincoln, USA. Her main area of interest is Life Sciences. Her area of expertise are Biochemistry, Enzymes, Protein Peptides, Protein purification, Enzyme kinetics, Enzymology, Enzyme mechanism, Industrial application of enzymes, Antioxidants and Antimicrobials, Redox biology and Oxidative stress, Thioldisulfide chemistry, Gaseous signaling molecules, Nitric oxide, Hydrogen sulfide, Carbon monoxide, Molecular biology, Yeast and bacterial expression system, Bioinformatics, Metabolic engineering in bacteria and yeast, Microbial Biochemistry and Biotechnology, Bio analytical chemistry, HPLC, GC, GC/MS, Spectroscopy. She has published 9 articles in national and international peer reviewed journals.
Area of Interest:
Chemistry
100%
Biochemistry
62%
Enzymology
90%
Redox Signaling
75%
Hydrogels
55%
Research Publications in Numbers
Books
0
0
Chapters
0
0
Articles
9
9
Abstracts
0
0
Selected Publications
- Houck, S., S. Singh and D.M. Cyr, 2012. Cellular responses to misfolded proteins and protein aggregates. Meth. Mol. Biol., 832: 455-461.
Direct Link | - Singh, S. and R. Banerjee, 2011. PLP-dependent H2S biogenesis. Biochimica et Biophysica Acta (BBA)-Proteins Proteomics, 1814: 1518-1527.
Direct Link | - Singh, S., D. Ballou and R. Banerjee, 2010. Pre-steady-state rapid reaction kinetic analysis of the H2S generating reactions catalyzed by cystathionine b-synthase. Biochemistry. .
- Karunakaran, V., Y. Sun, Z. Zhang, A. Bennabas, S. Singh, R. Banerjee and P.M. Champion, 2010. Investigations of low-frequency vibrational dynamics and ligand binding kinetics of cystathionine β-synthase. J. Phys. Chem. B., 114: 3294-3306.
CrossRef | - Weeks, C.L., S. Singh, P. Madzelan, R. Banerjee and T.G. Spiro, 2009. Heme regulation of human cystathionine β-synthase activity: Insights from fluorescence and raman spectroscopy. J. Am. Chem. Soc., 131: 12809-12816.
CrossRef | - Singh, S., P. Madzelan, J. Stasser, C.L. Weeks and D. Becker et al., 2009. Modulation of the heme electronic structure and cystathionine b-synthase activity by second coordination sphere ligands: The role of heme ligand switching in redox regulation. J. Inorg. Biochem., 103: 689-697.
CrossRef | PubMed | - Singh, S., D. Padovani, R. Leslie, T. Chiku and R. Banerjee, 2009. The relative contributions of cystathionine-β-synthase and g-cystathionase to H2S biogenesis via alternative transsulfuration reactions. J. Biol. Chem., 284: 22457-22466.
- Chiku, T., D. Padovani, W. Zhu, S. Singh, V. Vitvitsky and R. Banerjee, 2009. H2S biogenesis by human cystathionine γ-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia. J. Biol. Chem., 284: 11601-11612.
CrossRef | - Singh, S., P. Madzelan and R. Banerjee, 2007. Properties of an unusual heme cofactor in PLP-dependent cystathionineβ-synthase. Nat. Prod. Rep., 24: 631-639.
CrossRef | PubMed |