Dr. Nirmal  Kumar  Lohiya
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Dr. Nirmal Kumar Lohiya

Professor
University of Rajasthan, India


Highest Degree
Ph.D. in Reproductive Biology from University of Rajasthan, India

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Area of Interest:

Pharmacology and Toxicology
100%
Reproductive Biology
62%
Gynaecology
90%
Immunology
75%
Zoology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Mishra, P.K. and N.K. Lohiya, 2016. Prioritizing reproductive health: Can it be the real game changer for India? J. Reprod. Health Med., 2: 1-3.
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  2. Lohiya, N.K., K. Balasubramanian and A.S. Ansari, 2016. Indian folklore medicine in managing men's health and wellness. Andrologia, 48: 894-907.
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  3. Jagadish, N., S. Agarwal, N. Gupta, R. Fatima and S. Devi et al., 2016. Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer. J. Exp. Clin. Cancer Res., Vol. 35. 10.1186/s13046-016-0425-9.
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  4. Jagadish, N., D. Parashar, N. Gupta, S. Agarwal and V. Suri et al., 2016. Heat shock protein 70-2 (HSP70-2) is a novel therapeutic target for colorectal cancer and is associated with tumor growth. BMC Cancer, Vol. 16. 10.1186/s12885-016-2592-7.
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  5. Jagadish, N., D. Parashar, N. Gupta, S. Agarwal and A. Sharma et al., 2016. A novel cancer testis antigen target a-kinase anchor protein (AKAP4) for the early diagnosis and immunotherapy of colon cancer. OncoImmunology, Vol. 5. 10.1080/2162402X.2015.1078965.
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  6. Bunkar, N., N. Pathak, N.K. Lohiya and P.K. Mishra, 2016. Epigenetics: A key paradigm in reproductive health. Clin. Exp. Reprod. Med., 43: 59-81.
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  7. Bhargava, A., D.K. Mishra, S.K. Jain, R.K. Srivastava, N.K. Lohiya and P.K. Mishra, 2016. Comparative assessment of lipid based nano-carrier systems for dendritic cell based targeting of tumor re-initiating cells in gynecological cancers. Mol. Immunol., 79: 98-112.
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  8. Ansari, A.S., M. Hussain, S.R. Khan and N.K. Lohiya, 2016. Relative suitability of DMSO and NaHCO3 for reversal of RISUG® induced long-term contraception. Andrology, 4: 306-313.
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  9. Ansari, A.S., A. Badar, K. Balasubramanian and N.K. Lohiya, 2016. Contraception with RISUG® and functional reversal through DMSO and NaHCO3 in male rabbits. Asian J. Androl., .
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  10. Sharma, A., A.S. Ansari and N.K. Lohiya, 2015. Impact of body mass index (BMI) on sperm functional parameters and serum hormonal profile of infertile males. Int. J. Health Sci. Res., 5: 315-323.
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  11. Agarwal, S., D. Parashar, N. Gupta, N. Jagadish and A. Thakar et al., 2014. Sperm associated antigen 9 (SPAG9) expression and humoral response in benign and malignant salivary gland tumors. OncoImmunology, Vol. 3. 10.4161/2162402X.2014.974382.
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  12. Sinha, A., S. Agarwal, D. Parashar, A. Verma and S. Saini et al., 2013. Down regulation of SPAG9 reduces growth and invasive potential of triple-negative breast cancer cells: Possible implications in targeted therapy. J. Exp. Clin. Cancer Res., Vol. 32. 10.1186/1756-9966-32-69.
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  13. Saini, S., S. Agarwal, A. Sinha, A. Verma and D. Parashar et al., 2013. Gene silencing of A-kinase anchor protein 4 inhibits cervical cancer growth in vitro and in vivo. Cancer Gene Ther., 20: 413-420.
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  14. Kanojia, D., M. Garg, S. Saini, S. Agarwal and D. Parashar et al., 2013. Sperm associated antigen 9 plays an important role in bladder transitional cell carcinoma. Plos One, Vol. 8. 10.1371/journal.pone.0081348.
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  15. Goyal, S., B. Manivannan, G.R. Kumraj, A.S. Ansari and N.K. Lohiya, 2013. Evaluation of efficacy and safety of recombinant sperm-specific contraceptive vaccine in Albino mice. Am. J. Reprod. Immunol., 69: 495-508.
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  16. Ansari, A.S., I. Alam, M. Hussain, S.R. Khan and N.K. Lohiya, 2013. Evaluation of genotoxicity in leukocytes and testis following intra-vasal contraception with RISUG and its reversal by DMSO and NaHCO3 in Wistar albino rats. Reprod. Toxicol., 36: 53-59.
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  17. Ansari, A.S., C.S. Yadav and N.K. Lohiya, 2013. Testosterone and its analogs as a male contraceptive. Adv. Sexual Med., 3: 10-18.
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  18. Agarwal, S., S. Saini, D. Parashar, A. Verma and N. Jagadish et al., 2013. Expression and humoral response of A-kinase anchor protein 4 in cervical cancer. Int. J. Gynecological Cancer, 23: 650-658.
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  19. Agarwal, S., S. Saini, D. Parashar, A. Verma and A. Sinha et al., 2013. The novel cancer-testis antigen A-kinase anchor protein 4 (AKAP4) is a potential target for immunotherapy of ovarian serous carcinoma. Oncoimmunol., Vol. 2. 10.4161/onci.24270.
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  20. Shrivastava, S., A.S. Ansari and N.K. Lohiya, 2011. Fertility, developmental toxicity and teratogenicity in albino rats treated with methanol sub-fraction of Carica papaya seeds. Indian J. Pharmacol., 43: 419-423.
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  21. Purswani, S., G.P. Talwar, R. Vohra, R. Pal, A.K. Panda, N.K. Lohiya and J.C. Gupta, 2011. Mycobacterium indicus pranii is a potent immunomodulator for a recombinant vaccine against human chorionic gonadotropin. J. Reprod. Immunol., 91: 24-30.
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  22. Ansari, A.S., S. Shrivastava, S. Goyal and N.K. Lohiya, 2011. Observations on chromosomal aberrations following the administration of methanol Sub-Fraction of Carica papaya seeds for contraception in albino rats and rabbits. Int. J. Pharmacol., 7: 721-725.
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  23. Ansari, A.S., S. Shrivastava and N.K. Lohiya, 2011. Dominant lethal assay following administration of methanol sub-fraction of the seeds of Carica papaya. Pharmacologia, 2: 229-236.
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  24. Talwar, G.P., N.K. Lohiya and K.B. Garg, 2010. Praneem Polyherbal Microbicide for Curing AVD Syndrome and Elimination of HPV 16 in Women with Cervical Dysplasia Molecularly Positive for HPV 16. In: Fundamental and Translational Research on HIV/AIDS: Global Perspectives. Bandivdekar, A.H. and C.P. Puri (Ed.). National Institute for Research in Reproductive Health and Indian Council of Medical Research, Mumbai, India., pp: 85-97..
  25. Purswani, S., N.K. Lohiya and G.P. Talwar, 2010. Possibility and potential of a vaccine against human chorionic gonadotropin for family planning. Curr. Sci., 99: 169-176.
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  26. Lohiya, N.K., R. Suthar, A. Khandelwal, S. Goyal, A.S. Ansari and B. Manivannan, 2010. Sperm characteristics and teratology in rats following vas deferens occlusion with RISUG and its reversal. Int. J. Androl., 33: e198-e206.
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  27. Goyal, S., B. Manivannan, A.S. Ansari, S.C. Jain and N.K. Lohiya, 2010. Safety evaluation of long term oral treatment of methanol sub-fraction of the seeds of Carica papaya as a male contraceptive in albino rats. J. Ethnopharmacol., 127: 286-291.
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  28. Garg, K.B., I. Ganguli, A. Kriplani, N.K. Lohiya, J. Thulkar and G.P. Talwar, 2010. Metabolic properties of lactobacilli in women experiencing recurring episodes of bacterial vaginosis with vaginal pH≥5. Eur. J. Clin. Microbiol. Infect. Dis., 29: 123-125.
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  29. Vyas, H.K., R. Pal, R. Vishwakarma, N.K. Lohiya and G.P. Talwar, 2009. Selective killing of leukemia and lymphoma cells ectopically expressing hCGβ by a conjugate of curcumin with an antibody against hCG7beta; subunit. Oncol., 76: 101-111.
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  30. Vyas, H.K., R. Pal, N.K. Lohiya and G.P. Talwar, 2009. A partner monoclonal antibody to Moab 730 kills 100% of DU145 and PC3 androgen-independent cancer cells. J. Biosci., 34: 909-916.
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  31. Manivannan, B., R. Mittal, S. Goyal, A.S. Ansari and N.K. Lohiya, 2009. Sperm characteristics and ultrastructure of testes of rats after long-term treatment with the methanol subfraction of Carica papaya seeds. Asian J. Androl., 11: 583-599.
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  32. Goyal, S., B. Manivannan, A.S. Ansari and N.K. Lohiya, 2009. Safety evaluation of long term treatment of methanol sub-fraction of seeds of Carica papaya as a male contraceptive with particular emphasis on carcinogenicity in albino rats. Int. J. Pharmacol., 5: 114-125.
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  33. Garg, M., D. Kanojia, S. Salhan, S. Suri, A. Gupta, N.K. Lohiya and A. Suri, 2009. Sperm-associated antigen 9 is a biomarker for early cervical carcinoma. Cancer, 115: 2671-2683.
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  34. Lohiya, N.K., B. Manivannan, S. Goyal and A.S. Ansari, 2008. Sperm motility inhibitory effect of the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya in langur monkey, Presbytis entellus entellus. Asian J. Androl., 10: 298-306.
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  35. Garg, M., D. Kanojia, A. Khosla, N. Dudha and S. Sati et al., 2008. Sperm-associated antigen 9 is associated with tumor growth, migration and invasion in renal cell carcinoma. Cancer Res., 68: 8240-8248.
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  36. Ansari, A.S., S. Shrivastava, S. Goyal and N.K. Lohiya, 2008. Leading Plant Products for Fertility Regulation: A Review. In: Recent Advances and Challenges in Reproductive Health Research, Sharma, R.S., A. Rajanna and M. Rajalakshmi (Eds.). Indian Council of Medical Research, New Delhi, pp: 117-134.
  37. Ansari, A.S., S. Shrivastava and N.K. Lohiya, 2008. Novel Natural Products for Fertility Regulation. In: Handbook of Ethnopharmacology, Eddouks, M. (Ed.). Chapter 10, Research Signpost, Trivandrum, India, pp: 329-364.
  38. Ansari, A.S., A. Sharma and N.K. Lohiya, 2007. Does paternal occupation and lifestyle affects the embryo quality. J. Endocrinol. Reprod., 11: 15-22.
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  39. Lohiya, N.K., B. Manivannan and S. Garg, 2006. Toxicological investigations on the methanol sub-fraction of the seeds of Carica papaya as a male contraceptive in albino rats. Reprod. Toxicol., 22: 461-468.
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  40. Lohiya, N.K., A.S. Ansari, K. Mathivavan and S. Goyal, 2006. Influence of pollution and lifestyle on semen quality and reproduction: A review. Embryo Talk, 1: 21-31.
  41. Kumar, M., S. Sharma and N.K. Lohiya, 2006. Is It Still Possible to Develop Gossypol As An Ideal Male Contraceptive Pill? A Review. In: Advances in Reproductive Toxicology. Joshi, S.C. and A.S. Ansari (Ed.). Pointer Publishers, Jaipur, India., pp: 244-261..
  42. Ansari, A.S. and N.K. Lohiya, 2006. General and Reproductive Toxicity of Cadmium: An Overview. In: Advances in Reproductive Toxicology, Joshi, S.C. and A.S. Ansari, (Eds.). Pointer Publishers, Jaipur, pp: 110-128.
  43. Manivannan, B., S.S. Bhande, S. Panneerdoss, S. Sriram and N.K. Lohiya, 2005. Safety evaluation of long-term vas occlusion with styrene maleic anhydride and its non-invasive reversal on accessory reproductive organs in langurs. Asian J. Androl., 7: 195-204.
    PubMed  |  
  44. Lohiya, N.K., P.K. Mishra, N. Pathak, B. Manivannan, S.S. Bhande, S. Panneerdoss and S. Sriram, 2005. Efficacy trial on the purified compounds of the seeds of Carica papaya for male contraception in albino rat. Reprod. Toxicol., 20: 135-148.
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  45. Lohiya, N.K., B. Manivannan, S.S. Bhande, S. Panneerdoss and S. Garg, 2005. Perspectives of contraceptive choices for men. Ind. J. Exp. Biol., 43: 1042-1072.
    PubMed  |  
  46. Lohiya, N.K., B. Manivannan, R.S. Sharma, S. Panneerdoss and S. Garg, 2005. Langur monkey, Presbytis entellus entellus: An Animal Model for the Study of Human Reproduction. In: National Center for Primate Breeding and Research: Vision, Challenges and Opportunities. Puri, C.P. and N.K. Ganguly (Ed.). National Institute for Research in Reproductive Health and Indian Council of Medical Research, Mumbai, India., pp: 279-290..
  47. Lohiya, N.K., B. Manivannan, P.K. Mishra, S. Sriram, S.S. Bhande and S. Panneerdoss, 2005. Preclinical evaluation for noninvasive reversal following long-term vas occlusion with styrene maleic anhydride in langur monkeys. Contraception, 71: 214-226.
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  48. Sudha, R., L. Anantharaman, M.V. Sivaram, N. Mirsamadi and D. Choudhury et al., 2004. Linkage of Interactions in sickle hemoglobin fiber assembly: Inhibitory effect emanating from mutations in the AB region of the α-chain is annulled by a mutation at its EF corner. J. Biol. Chem., 279: 20018-20027.
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  49. Manivannan, B., P.K. Mishra, N. Pathak, S. Sriram, S.S. Bhande, S. Panneerdoss and N.K. Lohiya, 2004. Ultrastructural changes in the testis and epididymis of rats following treatment with the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya. Phytother. Res., 18: 285-289.
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  50. Mishra, P.K., B. Manivannan, N. Pathak, S. Sriram, S.S. Bhande, S. Panneerdoss and N.K. Lohiya, 2003. Status of spermatogenesis and sperm parameters in langur monkeys following Long-term vas occlusion with styrene maleic anhydride. J. Androl., 24: 501-509.
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  51. Lohiya, N.K., B. Manivannan and P.K. Mishra, 2003. Andrological Investigations for the Assessment of Infertility. In: Current Views on Fertility Management. Krishna, A., S.K. Singh and V. Tripathi (Ed.). Banaras Hindu University, Varanasi, India., pp: 97-117..
  52. Kamal, R., R.S. Gupta and N.K. Lohiya, 2003. Plants for male fertility regulation. Phytother. Res., 17: 579-590.
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  53. Manivannan, P.K. Mishra, N. Pathak, S. Sriram, S.S. Bhande, S. Panneerdoss and N.K. Lohiya, 2002. Current Advances in Male Contraception. In: Reproductive Biology and Comparative Endocrinology, Akbarsha, M.A. (Ed.). SRBCE, Chennai and BU, Tiruchirappali, India, pp: 23-24.
  54. Lohiya, N.K., B. Manivannam, P.K. Mishra, N. Pathak, S. Sririam, S.S. Bhande and S. Panneerdoss, 2002. Chloroform extract of Carica papaya seeds induces long-term reversible azoospermia in Langur monkey. Asian J. Androl., 41: 17-26.
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  55. Kathuria, S.R., R. Nath, R. Pal, O. Singh, R. Fischer, N.K. Lohiya and G.P. Talwar, 2002. Functional recombinant antibodies against human chorionic gonadotropin expressed in plants. Curr. Sci., 82: 1452-1457.
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  56. Lohiya, N.K., B. Manivannan, P.K. Mishra and N. Pathak, 2001. Vas deferens, a site of male contraception: An overview. Asian J. Androl., 3: 87-96.
    PubMed  |  Direct Link  |  
  57. Lohiya, N.K., B. Manivannan, P.K. Mishra and N. Pathak, 2001. Prospects of Developing a Plant Based Male Contraceptive Pill. In: Current Status in Fertility Regulation: Indigeneous and Modern Approaches, Chowdhury, S.R., C.M. Gupta and V.P. Kamboj (Eds.). Central Drug Research Institute, Lucknow, India, ISBN: 81-85042-17-9, pp: 99-119.
  58. Lohiya, N.K., B. Manivannan, P.K. Mishra and N. Pathak, 2001. Non-invasive Reversible Vas Occlusion with Styrene Maleic Anhydride: A Possible Alternative to Vasectomy. In: Sexual and Reproductive Health: Recent Advances, Future Directions Vol II. Puri, C.P. and P.F.A. Van Look (Ed.). New Age International (P) Ltd., Mumbai, India., pp: 249-268..
  59. Srivastava, S., A.S. Ansari and N.K. Lohiya, 2000. Ultrastructure of langur monkey epididymidis prior to and following vasectomy and vasovasostomy. Eur. J. Morphol., 38: 24-33.
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  60. Pathak, N., P.K. Mishra, B. Manivannan and N.K. Lohiya, 2000. Sterility due to inhibition of sperm motility by oral administration of benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya in rats. Phytomedicine, 7: 325-333.
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  61. Mishra, P.K., N. Pathak, B. Manivannan and N.K. Lohiya, 2000. Screening for the hormonal properties of the chloroform extract of Carica papaya Linn. seeds for antifertility investigation. Nat. Prod. Sci., 6: 5-10.
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  62. Lohiya, N.K., N. Pathak, P.K. Mishra and B. Manivannan, 2000. Contraceptive evaluation and toxicological study of aqueous extract of the seeds of Carica papaya in male rabbits. J. Ethnopharmacol., 70: 17-27.
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  63. Lohiya, N.K., L.K. Kothari, B. Manivannan, P.K. Mishra and N. Pathak, 2000. Human sperm immobilization effect of Carica papaya seed extracts: An in vitro study. Asian J. Androl., 2: 103-109.
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  64. Lohiya, N.K., B. Manivannan and P.K. Mishra, 2000. Repeated vas occlusion and non-invasive reversal with styrene maleic anhydride for male contraception in langur monkeys. Int. J. Androl., 23: 36-42.
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