1. Gupta, R., G.V. Rao, A.K. Nalla, C. Chetty and J.D. Klopfenstein et al., 2011. Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo. Int. J. Oncol., 38: 973-983.
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2. Gupta, R., C. Chetty, P. Bhoopathi, S. Lakka, S. Mohanam, J.S. Rao and D.E. Dinh, 2011. Downregulation of uPA/uPAR inhibits intermittent hypoxia-induced epithelial-mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells. Int. J. Oncol., 38: 733-744.
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3. Gupta, R., A.K. Nalla, V.R. Gogineni, C. Chetty and P. Bhoopathi et al., 2011. uPAR/Cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma. PLoS One, 6: e17123-e17123.
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4. Chetty, C., J.S. Rao and S.S. Lakka, 2011. Matrix metalloproteinase pharmacogenomics in non-small-cell lung carcinoma. Pharmacogenomics, 12: 535-546.
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5. Bhoopathi, P., C. Chetty, V.R. Gogineni, M. Gujrati, D.H. Dinh, J.S. Rao and S.S. Lakka, 2011. MMP-2 mediates mesenchymal stem cell tropism towards medulloblastoma tumours. Gene Ther., 10.1038/gt.2011.14.
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6. Veeravalli, K.K., C. Chetty, S. Ponnala, C.S. Gondi and S.S. Lakka et al., 2010. MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice. PLoS One, 5: e11583-e11583.
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7. Gondi, C.S., G.V. Rao, C. Chetty, V.R. Dasari and B. Gorantla et al., 2010. Induction of apoptosis in glioma cells requires cell-to-cell contact with human umbilical cord blood stem cells. Int. J. Oncol., 36: 1165-1173.
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8. Chetty, C., S.S. Lakka, P. Bhoopathi, K.K. Veeravalli and D. Fassett et al., 2010. Urokinase Plasminogen Activator Receptor and/or Matrix Metalloproteinase-9 inhibition induces apoptosis signaling through lipid rafts in Glioblastoma xenograft cells. Mol. Cancer Ther., 9: 2605-2617.
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9. Chetty, C., P. Bhoopathi, S.S. Lakka and J.S. Rao, 2010. MMP-2 alters VEGF expression via αVβ3 Integrin-mediated PI3K/AKT signaling in A549 lung cancer cells. Int. J. Cancer, 127: 1081-1095.
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10. Bhoopathi, P., C. Chetty, M. Gujrati, D.H. Dinh, J.S. Rao and S.L. Lakka, 2010. The role of MMP-9 in the anti-angiogenic effect of secreted protein acidic and rich in cysteine. Br. J. Cancer, 102: 530-540.
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11. Chetty, C., P. Bhoopathi, J.S. Rao and S.S. Lakka, 2009. Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells. Int. J. Cancer, 124: 2468-2477.
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12. Tsung, A.J., O. Kargiotis, C. Chetty, L.S. Lakka and M. Gujrati et al., 2008. Downregulation of matrix metalloproteinase-2 (MMP-2) utilizing adenovirus-mediated transfer of small interfering RNA (siRNA) in a novel spinal metastatic melanoma model. Int J. Oncol., 32: 557-564.
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13. Kargiotis, O., C. Chetty, V. Gogineni, C.S. Gondi and S.M. Pulukuri et al., 2008. uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo. Int. J. Oncol., 33: 937-947.
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14. Kargiotis, O., C. Chetty, C.S. Gondi, A.J. Tsung and D.H. Dinh et al., 2008. Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma. Oncogene, 27: 4830-4840.
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15. Chetty, C., S.S. Lakka, P. Bhoopathi, S. Kunigal, R. Geiss and J.S. Rao, 2008. Tissue inhibitor of metalloproteinase 3 suppresses tumor angiogenesis in matrix metalloproteinase 2-down-regulated lung cancer. Cancer Res., 68: 4736-4745.
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16. Bhoopathi, P., C. Chetty, S. Kunigal, V. Vanamala, J.S. Rao and S.L. Lakka, 2008. Blockade of tumor growth due to Matrix Metalloproteinase-9 inhibition is mediated by sequential activation of β1-integrin, ERK, and NF-κB. J. Biol.Chem., 283: 1545-1552.
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17. Rao, J.S., P. Bhoopathi, C. Chetty, M. Gujrati and S.S. Lakka, 2007. MMP-9 short interfering RNA induced senescence resulting in inhibition of medulloblastoma growth via p16INK4A and mitogen-activated protein kinase pathway. Cancer Res., 67: 4956-4964.
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18. Chetty, C., P. Bhoopathi, S.S. Lakka and J.S. Rao, 2007. MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line. Oncogene, 26: 7675-7683.
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19. Chetty, C., P. Bhoopathi, P. Joseph, S. Chittivelu, J.S. Rao and S.S. Lakka, 2006. Adenovirus-mediated small interfering RNA against Matrix Metalloproteinase-2 suppresses tumor growth and lung metastasis in mice. Mol. Cancer Ther., 5: 2289-2299.
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20. Rao, J.S., C.S. Gondi, C. Chetty, S. Chittivelu, P.A. Joseph and S.S. Lakka, 2005. Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus-mediated transfer of antisense uPAR and MMP-9 in non-small cell lung cancer cells. Mol. Cancer Ther., 4: 1399-1408.
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21. Chandramu, C., R.D. Manohar, D.G.L. Krupadanam and R.V. Dashavantha, 2003. Isolation, characterization and biological activity of betulinic acid and ursolic acid from Vitex negundo L. Phytother. Res., 17: 129-134.
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22. Chandramu, C., M. Rao and V.D. Reddy, 2003. High frequency induction of multiple shoots from nodal explants of Vitex negundo L. using sodium sulphate. J. Plant Biotechnol., 5: 107-113.
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