Dr. Rajesh Kumar Kesharwani
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Dr. Rajesh Kumar Kesharwani

Associate Professor
Department of Computer Application, NGB(DU), Prayagraj, India

Highest Degree
Ph.D. in Biomedical Sciences from Indian Institute of Information Technology, Allahabad, India

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Biography

Dr. Rajesh K. Kesharwani, has more than 11 years of research and 9 years of teaching experience in various institutes of India. He has received several awards, including the NASI-Swarna Jayanti Puruskar by The National Academy of Sciences of India. He has supervised 01 Ph.D., and more than 20 UG, PG students, has authored over 51 peer-reviewed articles, 20 book chapters, and 15 Books.

Area of Interest:

Biomedical Sciences
100%
Biochemistry
62%
Bioinformatics
90%
Molecualar Biology
75%
Drug Delivery
55%

Research Publications in Numbers

Books
6
Chapters
14
Articles
39
Abstracts
0

Selected Publications

  1. Sujatha, K., R.P. Deshpande, R.K. Kesharwani, P.P. Babu and R.R. Vedula, 2019. An efficient one-pot expeditious synthesis of 3-phenyl-1-(6-phenyl-7H-[1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazin-3-yl)-1H-pyrazol-5-amines via multicomponent approach. Synth. Commun., 49: 49-55.
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  2. Mishra, H., R.K. Kesharwani, D.B. Singh, S. Tripathi, S.K. Dubey and K. Misra, 2019. Computational simulation of inhibitory effects of curcumin, retinoic acid and their conjugates on GSK-3 beta. Network Model. Anal. Health Infor. Bioinfor., Vol. 8. 10.1007/s13721-018-0177-x.
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  3. Kesharwani, R.K., R.K. Kesharwani and A.K. Sharma, 2019. Enhancing the Therapeutic Efficacy of Herbal Formulations through Novel Drug Delivery Systems. IGI-Global, USA.
  4. Kesharwani, R.K., R.K. Kesharwani and A.K. Sharma, 2019. Advancements of Stem Cell Technology in Disease Prevention and Treatment. IGI-Global, USA.
  5. Kesharwani, R.K., A.K. Sharma and R.K. Kesharwani, 2019. Nutraceuticals and Dietary Supplements. Apple Academic Press, UK.
  6. Pavurala, S., K. Vaarla, R. Kesharwani, L. Naesens, S. Liekens and R.R. Vedula, 2018. Bis coumarinyl bis triazolothiadiazinyl ethane derivatives: Synthesis, antiviral activity evaluation and molecular docking studies. Synth. Commun., 48: 1494-1503.
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  7. Kesharwani, R.K., D.B. Singh, D.V. Singh and K. Misra, 2018. Computational study of curcumin analogues by targeting DNA topoisomerase II: A structure-based drug designing approach. Network Model. Anal. Health Inform. Bioinform., Vol. 7. 10.1007/s13721-018-0179-8.
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  8. Keservani, R.K., A.K. Sharma and R.K. Kesharwani, 2018. Nutraceutical and Functional Foods in Disease Prevention. Apple Academic Press, USA., Pages: 217.
  9. Keservani, R.K., A.K. Sharma and R.K. Kesharwani, 2018. Carriers For Brain Targeting. Apple Academic Press, UK., Pages: 593.
  10. Yadav, D., Y.B. Tripathi, P. Singh, R.K. Kesharwani and R.K. Keservani, 2017. Roles of AMP, ADP, ATP and AMPK in Healthy Energy Boosting and Prolonged Life Span. In: Sustained Energy for Enhanced Human Functions and Activity, Bagchi, D. (Ed.). Academic Press, USA., ISBN: 9780128054130, pp: 31-51.
  11. Singh, P., R.K. Kesharwani and R.K. Keservani, 2017. Protein, Carbohydrates and Fats: Energy Metabolism. In: Sustained Energy for Enhanced Human Functions and Activity, Bagchi, D. (Ed.)., Academic Press, USA.
  12. Singh, P., R.K. Kesharwani and R.K. Keservani, 2017. Protein, Antioxidants and Vitamins: Roles in Cellular Function and Metabolism. In: Sustained Energy for Enhanced Human Functions and Activity, Bagchi, D. (Ed.)., Academic Press, USA.
  13. Sharma, A.K., R.K. Keservani and R.K. Kesharwani, 2017. Nanobiomaterials: Applications in Drug Delivery. Apple Academic Press, USA., Pages: 528.
  14. Keservani, R.K., A.K. Sharma and R.K. Kesharwani, 2017. Drug Delivery Approaches and Nanosystems: Drug Targeting Aspects of Nanotechnology. Vol. 2, Apple Academic Press, USA., Pages: 398.
  15. Keservani, R.K., A.K. Sharma and R.K. Kesharwani, 2017. Drug Delivery Approaches and Nanosystems. Vol. 1, IGI-Global, USA.
  16. Tripathi, A., K. Misra and R.K. Kesharwani, 2016. Study of some piperine analogues on drugs efflux by targeting P-glycoprotein, an in silico approach. Lett. Drug Design Discovery, 13: 952-961.
  17. Singh, P., R.K. Kesharwani, K. Misra and S. Ibrahim, 2016. Modulation of erythrocyte Plasma Membrane Redox System (PMRS) activity by curcumin. Biochem. Res. Int., Vol. 2016. 10.1155/2016/6025245.
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  18. Sharma, A.K., R.K. Keservani and R.K. Kesharwani, 2016. Biosimilar Concept and Regulation. In: Handbook of Research on Novel Approaches for Drug Delivery, Keservani, R.K., A.K. Sharma and R.K. Kesharwani (Eds.)., IGI Global Publisher, USA.
  19. Khambete, H., R.K. Keservani, R.K. Kesharwani, N.P. Jain and C.P. Jain, 2016. Emerging Trends of Nanobiomaterials in Hard Tissue Engineering. In: Applications of Nanobiomaterials: Nanobiomaterials in Hard Tissue Engineering, Grumezescu, A.M. and W. Andrew (Eds.)., Elsevier, USA., pp: 63-101.
  20. Keservani, R.K., R.K. Kesharwani, A.K. Sharma, S.P. Gautam and S.K. Verma, 2016. Nutraceutical Formulations and Challenges: A Special Emphasis on Stability and Safety Evaluations. In: New Product Development in Nutraceuticals and Functional Foods: From Concept to Market, Bagchi, D. and S. Nair (Eds.)., Elsevier, USA.
  21. Keservani, R.K., R.K. Kesharwani and A.K. Sharma, 2016. Nanobiomaterials Involved in Medical Imaging Technologies. In: Applications of Nanobiomaterials: Nanobiomaterials in Hard Tissue Engineering, Grumezescu, A. and A.M. Holban (Eds.)., Elsevier, USA., pp: 301-323.
  22. Keservani, R.K., A.K. Sharma and R.K. Kesharwani, 2016. Recent Advances in Drug Delivery Technology. IGI-Global, USA., Pages: 510.
  23. Keservani, R.K., A.K. Sharma and R.K. Kesharwani, 2016. Nutracetical and Functional Foods for Cardiovascular Health. In: Food Process Engineering: Emerging Technologies and Innovations in Food Engineering, Meghwal, M. and M.R. Goyal (Eds.)., Apple Academic Press, CRC Press, Taylor and Francis, USA.
  24. Keservani, R.K., A.K. Sharma and R.K. Kesharwani, 2016. Novel Approaches for Drug Delivery. IGI Global, USA., Pages: 515.
  25. Keservani, R.K., A.K. Sharma and R.K. Kesharwani, 2016. An Overview and Therapeutic Applications of Nutraceutical and Functional Foods. In: Handbook of Research on Novel Approaches for Drug Delivery, Keservani, R.K., A.K. Sharma and R.K. Kesharwani (Eds.)., IGI Global Publisher, USA.
  26. Bhatt, S., S. Dhyani and R.K. Kesharwani, 2016. The quantitative variation of isolated soluble proteins from dried leaves of Ailanthus excelsa Roxb. World J. Pharm. Pharmaceut. Sci., 5: 2221-2226.
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  27. Bhatt, S., S. Dhyani and R.K. Kesharwani, 2016. The genetic fidelity assessment of Ailanthus excelsa's leaves between Mandsaur (M.P.) and Ratlam (M.P.) districts. Eur. J. Biomed. Pharmaceut. Sci., 3: 564-568.
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  28. Bharti, N., Y. Kumar, S. Tripathi, S.P. Gupta and R.K. Kesharwani, 2016. Environmental risk on reproductive health. IJERT., 5: 16-24.
  29. Vaarla, K., R.K. Kesharwani, K. Santosh, R.R. Vedula, S. Kotamraju and M.K. Toopurani, 2015. Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. Bioorg. Med. Chem. Lett., 25: 5797-5803.
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  30. Tripathi, A., D.V. Singh, R.K. Kesharwani and K. Misra, 2015. P-glycoprotein: A critical comparison of models depicting mechanism of drug efflux and role of modulators. Proc. Nat. Acad. Sci. India Sect. B: Biol. Sci., 85: 359-375.
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  31. Singh, P., R.K. Kesharwani, K. Misra and S.I. Rizvi, 2015. The modulation of erythrocyte Na+/K+-ATPase activity by curcumin. J. Adv. Res., 6: 1023-1030.
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  32. Kesharwani, R.K., V. Srivastava, P. Singh, S.I. Rizvi, K. Adeppa and K. Misra, 2015. A novel approach for overcoming drug resistance in breast cancer chemotherapy by targeting new synthetic curcumin analogues against aldehyde dehydrogenase 1 (ALDH1A1) and glycogen synthase kinase-3 β (GSK-3β). Applied Biochem. Biotechnol., 176: 1996-2017.
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  33. Kesharwani, R.K., P. Singh and R.K. Keservani, 2015. Green Coffee Bean Extract and Chlorogenic Acids: Chemistry and Novel Antioxidant Benefits. In: Health Benefits of Green Coffee Bean in Human, Bagchi, D. (Ed.)., CRC Press, Taylor and Francis, USA.
  34. Keservani, R.K., S. Singh, V. Singh, R.K. Kesharwani and A.K. Sharma, 2015. Nutraceuticals and Functional Foods in the Prevention of Mental Disorder. In: Nutraceutical and Functional Foods in Human Life and Disease Prevention, Bagchi, D., H.G. Preuss and A. Swaroop (Eds.)., CRC Press, Taylor and Francis, USA., pp: 255-268.
  35. Keservani, R.K., R.K. Kesharwani, A.K. Sharma and U. Jarouliya, 2015. Dietary Supplements, Nutraceutical and Functional Foods in Immune Response (Immunomodulators). In: Nutraceutical and Functional Foods in Human Life and Disease Prevention, Bagchi, D., H.G. Preuss and A. Swaroop (Eds.)., CRC Press, Taylor and Francis, Boca Raton, Florida, USA., pp: 343-358.
  36. Keservani, R.K., R.K. Kesharwani and A.K. Sharma, 2015. Pulmonary and Respiratory Health: Antioxidants and Nutraceuticals. In: Nutraceutical and Functional Foods in Human Life and Disease Prevention, Bagchi, D., H.G. Preuss and A. Swaroop (Eds.)., CRC Press, Taylor and Francis, Boca Raton, pp: 279-295.
  37. Keservani, R.K., R.K. Kesharwani and A.K. Sharma, 2015. Naturally Occurring Toxicants as Etiologic Agents of Food-borne Disease. In: Food Toxicology, Bagchi, D. and A. Swaroop (Eds.)., CRC Press, Taylor and Francis, USA.
  38. Singh, P., R.K. Kesharwani, K. Misra and S.I. Rizvi, 2014. In silico validation for the modulatory effect of tea catechins on erythrocyte Na+/K+-ATPase. Natural Prod. J., 4: 173-182.
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  39. Singh, D.B., M.K. Gupta, R.K. Kesharwani, M. Sagar, S. Dwivedi and K. Misra, 2014. Molecular drug targets and therapies for Alzheimer's disease. Transl. Neurosci., 5: 203-217.
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  40. Singh, D.V., S. Agarwal, R.K. Kesharwani and K. Misra, 2013. 3D QSAR and pharmacophore study of curcuminoids and curcumin analogs: Interaction with thioredoxin reductase. Interdisciplinary Sci. Comput. Life Sci., 5: 286-295.
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  41. Singh, D.B., M.K. Gupta, R.K. Kesharwani and K. Misra, 2013. Comparative docking and ADMET study of some curcumin derivatives and herbal congeners targeting β-amyloid. Network Model. Anal. Health Inform. Bioinform., 2: 13-27.
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  42. Sethi, R., R.K. Kesharwani, S. Haroon, J.D. Pandey and K. Misra, 2013. Study of mechanism of interaction of mercurochrome with CT-DNA by computation, fluorescence and electrophoretic methods. Proc. Nat. Acad. Sci. India Section A: Phys. Sci., 83: 97-103.
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  43. Manidhar, D.M., R.K. Kesharwani, N.B. Reddy, C.S. Reddy and K. Misra, 2013. Designing, synthesis and characterization of some novel coumarin derivatives as probable anticancer drugs. Med. Chem. Res., 22: 4146-4157.
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  44. Fatima, M., R.K. Kesharwani, K. Misra and S.I. Rizvi, 2013. Protective effect of theaflavin on erythrocytes subjected to in vitro oxidative stress. Biochem. Res. Int., Vol. 2013. 10.1155/2013/649759.
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  45. Singh, D.V., S. Agarwal, R.K. Kesharwani and K. Misra, 2012. Molecular modeling and computational simulation of the photosystem-II reaction center to address isoproturon resistance in Phalaris minor. J. Mol. Model., 18: 3903-3913.
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  46. Kesharwani, R.K., D.V. Singh, K. Misra and S.I. Rizvi, 2012. Plant polyphenols as electron donors for erythrocyte plasma membrane redox system: Validation through in silico approach. Org. Med. Chem. Lett., Vol. 2. 10.1186/2191-2858-2-12.
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  47. Adi, B.D., K.K. Raj, S.K. Anil, K.K. Rajesh and H.M. Gulam, 2012. Formulation and in vitro characterization of metoprolol tartrate loaded chitosan microspheres. Ars. Pharm., 53: 13-18.
  48. Kesharwani, R.K., V. Mahajan and K. Misra, 2011. Designing of a model for human amelogenin for predicting its role in mineralization during synthesis of tooth enamel, an in silico approach. IIOAB J., 2: 1-10.
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  49. Kesharwani, R.K. and K. Misra, 2011. Prediction of binding site for curcuminoids at human topoisomerase II α protein; an in silico approach. Curr. Sci., 101: 1060-1065.
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  50. Keservani, R.K., R.K. Kesharwani, N. Gujarathi and A.K. Sharma, 2011. Formulation and characterization of Piroxicam reconstituted suspension. J. Pharm. Cosmetol., 3: 69-76.
  51. Keservani, R.K., A.K. Sharma, M. Ayaz and R.K. Kesharwani, 2011. Novel drug delivery system for the vesicular delivery of drug by the niosomes. Int. J. Res. Controlled Release, 1: 1-8.
  52. Vyas, N., R.K. Kesearvani, S. Jain, R. Raghuvanshi, N.P. Gavatia, R.K. Kesharwani and A.K. Agrawal, 2010. Urolithiasis and its management. Der Pharm. Lett., 2: 457-466.
  53. Mahajan, V., R.K. Kesharwani and K. Misra, 2010. A structural study of matrix metalloproteinase 20 (MMP20): An in silico approach. Adv. Applied Sci. Res., 1: 158-165.
  54. Keservani, R.K., N. Vyas, S. Jain, R. Raghuvanshi, R.K. Kesharwani and A.K. Sharma, 2010. Nutraceuticals and functional food as future food. Der Pharm. Lett., 2: 106-116.
  55. Keservani, R.K., A.K. Sharma, R.K. Kesharwani, N. Vyas and A Chadoker, 2010. Nutritional supplements: An overview. Int. J. Curr. Pharm. Rev. Res., 1: 59-75.
  56. Jain, S., N. Vyas, R.K. Keservani, R. Raghuvanshi, R.K. Kesharwani, P. Jain and S. Bindaiya, 2010. Clinical research future aspects. Der Pharm. Lett., 2: 122-130.
  57. Gupta, S., B.S. Yadav, R. Kesharwani, K.P. Mishra and N.K. Singh, 2010. The role of nanodrugs for targeted drug delivery in cancer treatment. Arch. Applied Sci. Res., 2: 37-51.
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  58. Upadhyaya, J., R.K. Kesharwani and K. Misra, 2009. Metabolism, pharmacokinetics and bioavailability of ascorbic acid; synergistic effect in the presence of tocopherols and curcumin. J. Comput. Intelli. Bioinformat., 2: 77-84.
  59. Upadhyay, J., R.K. Kesharwani and K. Misra, 2009. Comparative study of antioxidants as cancer preventives through inhibition of HIF-1 alpha activity. Bioinformation, 4: 233-236.
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