Dr. Ekambaram  Ganapathy

Dr. Ekambaram Ganapathy

Post-doctoral Fellow
University of California, USA


Highest Degree
Ph.D. in Cancer Biology from University of California, Los Angeles, USA

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Area of Interest:

Molecular Sciences
100%
Cancer Biology
62%
Carcinogenesis
90%
Oxidative Stress
75%
Cancer
55%

Selected Publications

  1. Ganapathy, E., F. Su, D. Meriwether, A. Devarajan and V. Grijalva et al., 2012. D-4F, an apoA-I mimetic peptide, inhibits proliferation and tumorigenicity of epithelial ovarian cancer cells by upregulating the anti-oxidant enzyme MnSOD. Int. J. Cancer, 130: 1071-1081.
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  2. Feng, S., G. Victor, N. Kaveh, G. Ekambaram and M. David et al., 2012. HDL mimetics inhibit tumor development in both induced and spontaneous mouse models of colon cancer. Mol. Can. Ther., 11: 1311-1319.
    PubMed  |  
  3. Rajasekaran, D., J. Elavarasan, M. Sivalingam, E. Ganapathy, A. Kumar, K. Kalpana and D. Sakthisekaran, 2011. Resveratrol interferes with N-nitrosodiethylamine-induced hepatocellular carcinoma at early and advanced stages in male Wistar rats. Mol. Med. Report, 4: 1211-1217.
    CrossRef  |  PubMed  |  
  4. Imaizumi, S., M. Navab, C. Morgantini, C. Charles-Schoeman and F. Su et al., 2011. Dysfunctional high density lipoprotein and the potential of apoA-I mimetic peptides to normalize the composition and function of lipoproteins. Circ. J., 75: 1533-1538.
    PubMed  |  
  5. Gao, F., S.X. Vasquez, F. Su, S. Roberts and N. Shah et al., 2011. L-5F, an apolipoprotein A-I mimetic, inhibits tumor angiogenesis by suppressing VEGF/basic FGF signaling pathways. Integr. Biol., 32: 479-489.
    CrossRef  |  
  6. Nishigaki, I., P. Rajendran, R. Venugopal, G. Ekambaram, D. Sakthisekaran and Y. Nishigaki, 2010. Cytoprotective role of astaxanthin against glycated protein/iron chelate-induced toxicity in human umbilical vein endothelial cells. Phytother Res., 24: 54-59.
    PubMed  |  
  7. Nishigaki, I., B. Rajkapoor, P. Rajendran, R. Venugopal, G. Ekambaram, D. Sakthisekaran and Y. Nishigaki, 2010. Effect of fresh apple extract on glycated protein/iron chelate-induced toxicity in human umbilical vein endothelial cells in vitro. Nat. Prod. Res. Part A, 24: 599-609.
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  8. Venkatraman, M., D. Konga, R. Peramaiyan, E. Ganapathy and S. Dhanapal, 2008. Reduction of mitochondrial oxidative damage and improved mitochondrial efficiency by administration of crocetin against benzo[a]pyrene induced experimental animals. Biol. Pharm. Bull., 31: 1639-1645.
    PubMed  |  
  9. Venkatesan, P.N., P. Rajendran, G. Ekambaram and D. Sakthisekaran, 2008. Combination therapeutic effect of cisplatin along with Solanum trilobatum on benzo(a)pyrene induced experimental lung carcinogenesis. Nat. Prod. Res., 22: 1094-1106.
    PubMed  |  
  10. Rajendran, P., R. Venugopal, G. Ekambaram, A. Aadithya and D. Sakthisekaran, 2008. Rehabilating activity of mangiferin in benzo(a) pyrene induced lung carcinogenesis. Asian J. Biochem., 36: 118-125.
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  11. Rajendran, P., G. Ekambaram, V. Magesh and D. Sakthisekaran, 2008. Chemopreventive efficacy of mangiferin against benzo(a)pyrene induced lung carcinogenesis in experimental animals. Environ. Toxicol. Pharmacol., 26: 278-282.
    PubMed  |  
  12. Rajendran, P., G. Ekambaram and D. Sakthisekaran, 2008. Protective role of mangiferin against Benzo (a) pyrene induced lung carcinogenesis in experimental animals. Biol. Pharm. Bull., 31: 1053-1058.
    PubMed  |  Direct Link  |  
  13. Rajendran, P., G. Ekambaram and D. Sakthisekaran, 2008. Effect of mangiferin on benzo(a)pyrene induced lung carcinogenesis in experimental swiss albino mice. Nat. Prod. Res., 22: 672-680.
    PubMed  |  
  14. Rajendran, P., G. Ekambaram and D. Sakthisekaran, 2008. Cytoprotective effect of mangiferin on benzo(a) pyrene induced lung carcinogenesis in swiss albino mice. Basic Clin. Pharmacol. Toxicol., 103: 137-142.
    PubMed  |  
  15. Nishigaki, I., R. Venugopal, P. Rajendran, G. Ekambaram, D. Sakthisekaran and Y. Nishigaki, 2008. Effect of extract of pomegranate (Punica granatum L) on glycated protein-iron chelate-induced toxicity: An in vitro study on HUVECs. J. Health Sci., 54: 441-449.
    CrossRef  |  
  16. Ekambaram, G., P. Rajendran, V. Magesh and D. Sakthisekaran, 2008. Naringenin reduces tumor size and weight lost in N-methyl-N-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats. Nutr. Res., 28: 106-112.
    PubMed  |  
  17. Ekambaram, G., P. Rajendran, R. Devaraja, V. Magesh and D. Sakthisekaran, 2008. Modulatory effect of naringenin on N-methyl-N-nitro-N-nitrosoguanidine and saturated sodium chloride promoted gastric carcinogenesis in wistar albino Male rats. Clin. Exp. Pharmacol. Physiol., 35: 1190-1196.
  18. Ekambaram, G., P. Rajendran, R. Devaraja, R. Muthuvel and D. Sakthisekaran, 2008. Impact of naringenin on glycoprotein levels in N-methyl-N-nitro-N-nitrosoguanidine induced experimental gastric carcinogenesis. Anticancer Drugs, 19: 885-890.
    PubMed  |  
  19. Magesh, V., J. Prince Vijeya Singh, K. Selvendiran, G. Ekambaram and D. Sakthisekaran, 2006. Antitumour activity of crocetin in accordance to tumor incidence, antioxidant status, drug metabolizing enzymes and histopathological studies. Mol. Cell Biol., 287: 127-135.
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  20. McCance, D.R., D.G. Dyer, J.A. Dunn, K.E. Bailie and S.R. Thorpe et al., 1993. Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus J. Clin. Invest., 91: 2470-2478.
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