Dr. Suresh Devraj Sharma
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Dr. Suresh Devraj Sharma

Post-doctoral Fellow
Pennsylvania State University, USA

Highest Degree
Ph.D. in Life Sciences from University of Mumbai, India

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Dr. Suresh Sharma received Doctor of Philosophy in the area of Life Sciences (Enzymology) from University of Mumbai India. He was a CSIR-Post Doctoral Fellow at the Tata Memorial Cancer Rsearch Institute (CRI), Mumbai, India where he worked on viral vectors/delivery systems combined with drug analogues to find cure for head and neck cancers. Dr. Sharma is currently working as a Research Associate (faculty level) at the Pennsylvania State University, University Park, PA, USA on various aspects of positive strand RNA viruses. He has several invited reviews and excellent research papers published in peer-reviewed, high impact journals. Dr. Sharma`s research interest includes biochemical study of HCV NS5A protein; RNA binding properties of NS5A as a target for drug design; cell culture studies with HCV-sub-genomic replicons with an aim of discovering novel viral-host targets for drug design.

Area of Interest:

Biomedical Sciences
Hepatitis Viruses
Life Sciences
Biological Chemistry

Research Publications in Numbers


Selected Publications

  1. Sharma, S.D., 2010. Hepatitis C virus: Molecular biology and current therapeutic options. Indian J. Med. Res., 131: 17-34.
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  2. Sharma, S.D., G. Raghuraman, M.S. Lee, N.R. Prabhakar and G.K. Kumar, 2009. Intermittent hypoxia activates peptidylglycine alpha-amidating monooxygenase in rat brain stem via reactive oxygen species-mediated proteolytic processing. J. Applied Physiol., 106: 12-19.
    CrossRef  |  
  3. Mackintosh, S.G., J.Z. Lu, J.B. Jordan, M.K. Harrison and B. Sikora et al., 2006. Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus. J. Biol. Chem., 281: 3528-3535.
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  4. Kumar, G.K., V. Rai, S.D. Sharma, D.P. Ramakrishnan, Y.J. Peng, D. Souvannakitti and N.R. Prabhakar, 2006. Chronic intermittent hypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenal medulla via oxidative stress. J. Physiol., 575: 229-239.
    CrossRef  |  
  5. Huang, L., J. Hwang, S.D. Sharma, M.R.S. Hargittai and Y. Chen et al., 2005. Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein. J. Biol. Chem., 280: 36417-36428.
    CrossRef  |  
  6. Huang, L., E.V. Sineva, M.R. Hargittai, S.D. Sharma, M. Suthar, K.D. Raney and C.E. Cameron, 2004. Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli. Protein Exp. Purif., 37: 144-153.
    PubMed  |  
  7. Sharma, S.D., B.N. Pandey, K.P. Mishra and S. Sivakami, 2002. Amadori product and age formation during nonenzymatic glycosylation of bovine serum albumin in vitro. J. Biochem. Mol. Biol. Biophys., 6: 233-242.
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  8. Sharma, S.D. and S. Sivakami, 1998. Responses of intestinal and renal alpha-glycosidases to alloxan and streptozotocin-induced diabetes: A comparative study. Biochem. Mol. Biol. Int., 44: 647-656.
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