Dr. Siva Reddy Challa
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Dr. Siva Reddy Challa

Research Collaborator
Department of Cancer Biology and Pharmacology, University Illinois College of Medicine, Peoria, USA

Highest Degree
Ph.D. in Pharmacology from Andhra University College of Pharmaceutical Sciences, India

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Area of Interest:

Pharmacology and Toxicology
100%
Stroke
62%
Immunoblotting Techniques
90%
Neuropathic Pain
75%
Plasmodium Blood
55%

Research Publications in Numbers

Books
0
Chapters
1
Articles
53
Abstracts
9

Selected Publications

  1. Rapaka, D., V.R. Bitra, S.R. Challa and P.C. Adiukwu, 2022. mTOR signaling as a molecular target for the alleviation of Alzheimers disease pathogenesis. Neurochem. Int., Vol 155. 10.1016/j.neuint.2022.105311.
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  2. Challa, S.R., K.R. Nalamolu, C.A. Fornal, B.C. Wang and R.C. Martin et al., 2022. Therapeutic efficacy of matrix metalloproteinase-12 suppression on neurological recovery after ischemic stroke: Optimal treatment timing and duration. Front. Neurosci., 10.3389/fnins.2022.1012812.
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  3. Challa, S.R., K.R. Nalamolu, C.A. Fornal, A. Mohandass, J.P. Mussman et al., 2022. The interplay between MMP-12 and t-PA in the brain after ischemic stroke. Neurochem. Int. Vol. 161. 10.1016/j.neuint.2022.105436.
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  4. Challa, S., C.A. Fornal, C. Schaibley, V. Sama, A. Kashyap, J.D. Klopfenstein and K. Veeravalli, 2022. Abstract TP232: Post-stroke suppression of matrix metalloproteinase-12 attenuates the expression of M1 and M2 markers and prevents the elevation of other matrix metalloproteinases. Stroke, Vol. 53. 10.1161/STR.53.SUPPL_1.TP232.
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  5. Rapaka, D., V.R. Bitra, S.R. Challa and P.C. Adiukwu, 2021. Potentiation of microglial endocannabinoid signaling alleviates neuroinflammation in Alzheimer's disease. Neuropeptides, Vol. 90. 10.1016/j.npep.2021.102196.
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  6. Nalamolu, K.R., S.R. Challa, C.A. Fornal, N.A. Grudzien and L.C. Jorgenson et al., 2021. Attenuation of the induction of TLRS 2 and 4 mitigates inflammation and promotes neurological recovery after focal cerebral ischemia. Transl. Stroke Res., 12: 923-936.
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  7. Nalamolu, K.R., B. Chelluboina, C.A. Fornal, S.R. Challa and D.M. Pinson et al., 2021. Stem cell treatment improves post stroke neurological outcomes: a comparative study in male and female rats. Stroke Vasc. Neurol., 6: 519-527.
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  8. Bonam S.R., M. Sekar, G.S. Guntuku, S.G. Nerella, K.M.A. Pawar and S.R Challa et al., 2021. Role of pharmaceutical sciences in future drug discovery. Future Drug Discov., Vol. 3. 10.4155/fdd-2021-0005.
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  9. Rama, R., M. Siva, B. Ramya, C. Vennela and N. Sree et al., 2020. Effect of chrysin on mechanical hyperalgesia in chronic constriction injury-induced neuropathic pain in rat model. Int. J. Appl. Basic Med. Res., 10: 189-193.
    CrossRef  |  
  10. Nalamolu, K.R., S.R. Challa, C.A. Fornal, R.C. Martin and E.A. Olson et al., 2020. MMP‐12 knockdown during acute and chronic phases promotes post‐stroke neurological recovery. FASEB J., Vol. 34. 10.1096/FASEBJ.2020.34.S1.06135.
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