Dr. Dinesh Kacha
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Dr. Dinesh Kacha

Researcher & Drug Discovery
Benmoon Pharma Research Pvt. Ltd., Ahmedabad, Gujarat, India


Highest Degree
PostDoc. in Ayurveda Medicine and Surgery from Gujarat Ayurved University, Jamnagar, Gujarat, India

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Biography

The purpose of the "PHPC compound research study on cancer" is to develop safe and effective methods to prevent, detect, diagnose, treat, and, ultimately, cure the collections of diseases we call cancer. Ideas for cancer research studies are inspired by findings from earlier research, clinical trials, research on other cancers, and even findings from research done on other diseases, such as diabetes or immune disorders. Its aim is to reduce the number of deaths from cancer.

The research reports that covers cytotoxicity study evaluated for cytotoxicity against human adenocarcinoma cell for performing Anti - Cancer Activity effect on cellular DNA damage with his research called PHPC Compound has shown significant reduction in occurrence of tumor, reduction in tumor size and volume, having conducting clinical researches, investigating methods of prevention, diagnosis & treatment studies for several years and have led Dr. Dinesh Kacha for this global recognition. The results revealed that the formulation showed significant cytotoxicity on cell line. Overall, the cell growth inhibition by the PHPC observed in this study synergistic response rates. In brief, PHPC Compound has showing promising level of results in experimental models.

Dr. Dinesh Kacha holds Excellent command over research, experimentation thorough knowledge of and inherent interest in subjects such as Diabetes & Cancer. Dedication and passion towards cancer research to increase the body of scientific knowledge on topics related to medicine from investigating the underlying basis of health or disease, to conducting clinical research and investigating methods of prevention, diagnosis and treatment of human disorders.

Researches & Studies A Report Of Anti-cancer activity (In vitro) of herbal formulation-PHPC Compound A Report Of Acute Oral Toxicity Study Of PHPC Compound To evaluate protective effect of in 5-fluorouracil (5 FU) induced toxicity A Report Of Sub-chronic (90-days) Oral Toxicity Study of PHPC Compound A Report of Study of PHPC Compound in 7,12-Dimethylbenz(a)anthracene induced Breast cancer Evaluation of effect of formulation “PHPC Compound” on cellular DNA damage Protective effect of PHPC Compound against 5-FU induced toxicity study.

Recommendation Women breast cancer is the most important cause of mortality in the world. Now a day, some cytotoxic agents are used for its treatment including 5- flurouracil, doxorubicin, daunorubicin, bleomycin, and cisplastin. However, they are costly and known to induce several side effects such as myelosuppression, anemia, and most importantly the generation of cellular resistance. For this, it is important to find alternative therapies or drugs to overcome these drawbacks. Therefore in the present study,the polyherbal formulation screened for its anticancer activity using MCF-7 cell lines. The formulation PHPC Compound was subjected to cell proliferation assay by MTT. The results revealed that the formulation showed significant cytotoxicity on MCF-7 cell line. Overall, the cell growth inhibition by the polyherbal formulation observed in this study synergistic response rates. It has known that cytotoxicity is mainly through apoptosis or necrosis.

Conclustion PHPC Compound significantly decreases the level of WBC count, which was increased incasde of diseased control group and indivative of host immune response due to tumor growth. But this reduction in WBC count by PHPC Compound treatment indicates that it decreases host immune response, which many be indicative of its suppression of growth of tumor

Area of Interest:

Drug Discovery
100%
Cancer Biology
62%
Immunofluorescence
90%
Cell Culture
75%
Cancer Research
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
4
Abstracts
0