Dr. Hifzur R. Siddique
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Dr. Hifzur R. Siddique

Senior Assistant Professor
Department of Zoology, Aligarh Muslim University, Aligarh, Uttar Pradesh, India


Highest Degree
Ph.D. in Embryo Toxicology from CSIR-Indian Institute of Toxicology Research, India

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Area of Interest:

Biomedical Sciences
100%
Cell Culture
62%
Cancer Research
90%
Biotechnology
75%
Immunofluorescence
55%

Research Publications in Numbers

Books
0
Chapters
15
Articles
99
Abstracts
4

Selected Publications

  1. Yeh, D.W., X. Zhao, H.R. Siddique, M. Zheng and H.Y. Choi et al., 2023. MSI2 promotes translation of multiple IRES-containing oncogenes and virus to induce self-renewal of tumor initiating stem-like cells. Cell Death Discovery, Vol. 9. 10.1038/s41420-023-01427-9.
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  2. Singh, D., M.A. Khan, K. Akhtar, S. Rehman, S. Parveen, K.M.Y. Amin and H.R. Siddique, 2023. Protective effects of a polyherbal medicine, Majoon Suranjan against bisphenol-A induced genetic, oxidative and tissue damages. Drug Chem. Toxicol., 46: 1057-1069.
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  3. Singh, D., M.A. Khan and H.R. Siddique, 2023. Role of epigenetic drugs in sensitizing cancers to anticancer therapies: Emerging trends and clinical advancements. Epigenomics, 15: 517-537.
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  4. Singh, D. and H.R. Siddique, 2023. Epithelial-to-mesenchymal transition in cancer progression: Unraveling the immunosuppressive module driving therapy resistance. Cancer Metastasis Rev., 10.1007/s10555-023-10141-y.
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  5. Mishra, A., S.K. Maurya, A. Singh, H. Siddique, S.K. Samanta and N. Mishra, 2023. Neolamarckia cadamba (Roxb.) Bosser (Rubiaceae) extracts: Promising prospects for anticancer and antibacterial potential through in vitro and in silico studies. Med. Oncol., Vol. 40. 10.1007/s12032-023-01971-5.
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  6. Liu, G.L., J.T. Zheng, C.Z. Huang, S.F. Sun and X.F. Liu et al., 2023. Coupling effect of micro-textured tools and cooling conditions on the turning performance of aluminum alloy 6061. Adv. Manuf., 11: 663-681.
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  7. Khan, M.A., D. Singh, M. Jameel, S.K. Maurya, S. Singh, K. Akhtar and H.R. Siddique, 2023. Lupeol, an androgen receptor inhibitor, enhances the chemosensitivity of prostate cancer stem cells to antiandrogen enzalutamide-based therapy. Toxicol. Appl. Pharmacol., Vol. 478. 10.1016/j.taap.2023.116699.
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  8. Khan, M.A., D. Singh, H. Fatma, K. Akhtar, F. Arjmand, S. Maurya and H.R. Siddique, 2023. Antiandrogen enzalutamide induced genetic, cellular, and hepatic damages: Amelioration by triterpene Lupeol. Drug Chem. Toxicol., 46: 380-391.
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  9. Jameel, M., M.F. Alam, H. Fatma, D. Singh and M.A. Khan et al., 2023. Flubendiamide induced genetic and cellular damages directly influence the life cycle of the oriental leaf worm, Spodoptera litura. Pestic. Biochem. Physiol., Vol. 193. 10.1016/j.pestbp.2023.105448.
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  10. Jameel, M., H. Fatma, L.A. Nadtochii and H.R. Siddique, 2023. Molecular insight into prostate cancer: Preventive role of selective bioactive molecules. Life, Vol. 13. 10.3390/life13101976.
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  11. Gupta, M., D. Singh, S. Rastogi, H.R. Siddique and Noura Al-Dayan et al., 2023. Anti-cancer activity of guggulsterone by modulating apoptotic markers: A systematic review and meta-analysis. Front. Pharmacol., Vol. 14. 10.3389/fphar.2023.1155163.
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  12. Fatma, H., M. Jameel, K. Akhtar, M.A. Ansari and H.R. Siddique, 2023. Implication of lupeol in compensating sorafenib-induced perturbations of redox homeostasis: A preclinical study in mouse model. Life Sci., Vol. 322. 10.1016/j.lfs.2023.121647.
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  13. Fatma, H., M. Jameel and H.R. Siddique, 2023. An update on phytochemicals in redox homeostasis: “Virtuous or Evil” in cancer chemoprevention? Chemistry, Vol. 5. 10.3390/chemistry5010017.
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  14. Fatma, H. and H.R. Siddique, 2023. Research and patents status of selected phytochemicals against cancer: How close and how far? Recent Pat. Anti-Cancer Drug Discovery, 18: 428-447.
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  15. Fatma, H. and H.R. Siddique, 2023. Cancer cell plasticity, stem cell factors, and therapy resistance: How are they linked? Cancer Metastasis Rev., 10.1007/s10555-023-10144-9.
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  16. Fatma, H. and H.R. Siddique, 2023. Aurora Kinase A and Related Downstream Molecules: A Potential Network for Cancer Therapy. In: Advances in Protein Chemistry and Structural Biology, Donev, R. (Ed.), Academic Press, Cambridge, Massachusetts, ISBN: 9780443131813, pp: 115-145.
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  17. Yousuf, S., H.R. Siddique, F. Arjmand and S. Tabassum, 2022. Functionalized graphene oxide loaded GATPT as rationally designed vehicle for cancer-targeted drug delivery. J. Drug Delivery Sci. Technol., Vol. 71. 10.1016/j.jddst.2022.103281.
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  18. Singh, D., M.A. Khan, K. Akhtar, F. Arjmand and H.R. Siddique, 2022. Apigenin alleviates cancer drug Sorafenib induced multiple toxic effects in Swiss albino mice via anti-oxidative stress. Toxicol. Appl. Pharmacol., Vol. 447. 10.1016/j.taap.2022.116072.
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  19. Singh, D., M.A. Khan and H.R. Siddique, 2022. Specific targeting of cancer stem cells by immunotherapy: A possible stratagem to restrain cancer recurrence and metastasis. Biochem. Pharmacol., Vol. 198. 10.1016/j.bcp.2022.114955.
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  20. Singh, D., M.A. Khan and H.R. Siddique, 2022. Role of p53-miRNAs circuitry in immune surveillance and cancer development: A potential avenue for therapeutic intervention. Sem. Cell Dev. Biol., 124: 15-25.
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  21. Singh, D., M. Gupta, M. Sarwat and H.R. Siddique, 2022. Apigenin in cancer prevention and therapy: A systematic review and meta-analysis of animal models. Crit. Rev. Oncol. Hematol., Vol. 176. 10.1016/j.critrevonc.2022.103751.
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  22. Maurya, S.K., H. Fatma, A.K. Maurya, N. Mishra and H.R. Siddique, 2022. Role of lupeol in chemosensitizing therapy-resistant prostate cancer cells by targeting MYC, β-catenin and c-FLIP: In silico and In vitro studies. In Silico Pharmacol., Vol. 10. 10.1007/s40203-022-00131-3.
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  23. Khursheed, S., H.R. Siddique, S. Tabassum and F. Arjmand, 2022. Water soluble transition metal [Ni(ii), Cu(ii) and Zn(ii)] complexes of N-phthaloylglycinate bis(1,2-diaminocyclohexane). DNA binding, pBR322 cleavage and cytotoxicity. Dalton Trans., 51: 11713-11729.
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  24. Khan, M.A., D. Singh, A. Arif, K.K. Sodhi and D.K. Singh et al., 2022. Protective effect of green synthesized selenium nanoparticles against doxorubicin induced multiple adverse effects in swiss albino mice. Life Sci., Vol. 305. 10.1016/j.lfs.2022.120792.
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  25. Singh, S., A. Numan, H.H. Somaily, B. Gorain and S. Ranjan et al., 2021. Nano-enabled strategies to combat methicillin-resistant Staphylococcus aureus. Mater. Sci. Eng.: C, Vol. 129. 10.1016/j.msec.2021.112384.
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  26. Singh, D., P. Kesharwani, N.A. Alhakamy and H.R. Siddique, 2021. Accentuating circRNA-miRNA-transcription factors axis: A conundrum in cancer research. Front. Pharmacol., Vol. 12. 10.3389/fphar.2021.784801.
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  27. Singh, D., M.A. Khan and H.R. Siddique, 2021. Therapeutic implications of probiotics in microbiota dysbiosis: A special reference to the liver and oral cancers. Life Sci., Vol. 285. 10.1016/j.lfs.2021.120008.
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  28. Fatma, H. and H.R. Siddique, 2021. Pluripotency inducing Yamanaka factors: Role in stemness and chemoresistance of liver cancer. Expert Rev. Anticancer Ther., 21: 853-864.
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  29. Arshad, F., M.P. Sk, S.K. Maurya and H.R. Siddique, 2021. Mechanochemical synthesis of sulfur quantum dots for cellular imaging. ACS Appl. Nano Mater., 4: 3339-3344.
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  30. Yousuf, S., F. Arjmand, H.R. Siddique, M.S. Ali, H.A. Al-Lohedan and S. Tabassum, 2020. Biophysical binding profile with ct-DNA and cytotoxic studies of a modulated nanoconjugate of umbelliferone cobalt oxide loaded on graphene oxide (GO) as drug carrier. J. Biomol. Struct. Dyn., 40: 4558-4569.
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  31. Fatma, H., S.K. Maurya and H.R. Siddique, 2020. Epigenetic modifications of c-MYC: Role in cancer cell reprogramming, progression and chemoresistance. Sem. Cancer Biol., 83: 166-176.
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