Biography

Dr. Razia Khanam holds a position of Associate Professor at Department of Pharmacology, Gulf Medical University, Ajman, UAE. She earned her PhD in Pharmacology from Jamia Hamdard (Hamdard University), New Delhi. Dr. Razia is having 15 years research and teaching experience. Previously she was appointed as Lecturer and Senior Assistant Professor at Faculty of Pharmacy Jamia Hamdard, New Delhi. Her main area of research interest focuses on rodent behavioral testing (depression associated with diabetes, anxiety, memory, inflammation, epilepsy etc.) and neurotransmitter estimations in rodents and she is involve in studying depression and its association with other diseases like diabetes, epilepsy, status of newer antidepressants on glucose homeostasis, diabetes-induced depression, oxidative stress and the augmentation and combination strategies in treating treatment-resistant depression. She has completed 2 research projects as principal investigator. Dr. Razia is also serving as reviewer for journals such as Psychoneuroendocrinology, Neuroscience Letters, Basic & Clinical Pharmacology & Therapeutics, Nutrition & Metabolism, Indian Journal of Experimental Biology, and Human and Experimental Therapeutics. Dr. Razia has published 47 research articles in journals, 1 book, and 24 abstracts contributed as author/co-author. She has supervised/co-supervised number of student’s thesis. She also participated in various national and international conferences.

Area of Interest:

Pharmacology and Toxicology

100%

Pharmaceutical Sciences

62%

Depression

90%

Drug Delivery

75%

Pharmacology

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
0

Abstracts
0

Selected Publications

Thomas, J., R. Khanam and D. Vohora, 2016. Augmentation of effect of venlafaxine by folic acid in behavioural paradigms of depression in mice: Evidence of serotonergic and pro-inflammatory cytokine pathways. Pharmacol. Rep., 68: 396-403.
CrossRef | PubMed | Direct Link |
Hass, C., B.P. Panda, R. Khanam, A.K. Najmi and M. Akhtar, 2016. Histamine H3 receptor agonist imetit attenuated isoproterenol induced renin angiotensin system and sympathetic nervous system overactivity in myocardial infarction of rats. Drug Res., .
Yadav, C.H., A.K. Najmi, M. Akhtar and R. Khanam, 2015. Cardioprotective role of H3R agonist imetit on isoproterenol-induced hemodynamic changes and oxidative stress in rats. Toxicol. Mech. Methods, 25: 235-240.
CrossRef | PubMed | Direct Link |
Thomas, J., R. Khanam and D. Vohora, 2015. A validated HPLC-UV method and optimization of sample preparation technique for norepinephrine and serotonin in mouse brain. Pharm. Biol., 53: 1539-1544.
CrossRef | PubMed | Direct Link |
Rohilla, A., A. Ahmad, M.U. Khan and R. Khanam, 2015. A comparative study on the cardioprotective potential of atorvastatin and simvastatin in hyperhomocysteinemic rat hearts. Eur. J. Pharmacol., 764: 48-54.
CrossRef | PubMed | Direct Link |
Mahmood, D., K.K. Pillai, R. Khanam, K. Jahan, D. Goswami and M. Akhtar, 2015. The Effect of subchronic dosing of ciproxifan and clobenpropit on dopamine and histamine levels in rats. J. Exp. Neurosci., 9: 73-80.
CrossRef | PubMed | Direct Link |
Kwatra, M., V. Kumar, A. Jangra, M. Mishra and S. Ahmed et al., 2015. Ameliorative effect of naringin against doxorubicin-induced acute cardiac toxicity in rats. Pharm. Biol., 54: 637-647.
CrossRef | PubMed | Direct Link |
Dubey, V.K., F. Ansari, D. Vohora and R. Khanam, 2015. Possible involvement of corticosterone and serotonin in antidepressant and antianxiety effects of chromium picolinate in chronic unpredictable mild stress induced depression and anxiety in rats. J. Trace Elem. Med. Biol., 29: 222-226.
CrossRef | PubMed | Direct Link |
Bhowmik, M., R. Khanam, N. Saini and D. Vohora, 2015. Activation of AKT/GSK3β pathway by TDZD-8 attenuates kainic acid induced neurodegeneration but not seizures in mice. Neurotoxicol., 46: 44-52.
CrossRef | PubMed | Direct Link |
Agarwal, A.K., S.I. Shehnaz, R. Khanam and M. Arifulla, 2015. Coffee in class: An alternative to animal experiments in pharmacology? Altern. Lab. Anim., 43: 17-21.
PubMed | Direct Link |
Shahzad, N., J. Ahmad, W. Khan, S.S. Al-Ghamdi and M.R. Ain et al., 2014. Interactions of atenolol with alprazolam/escitalopram on anxiety, depression and oxidative stress. Pharmacol. Biochem. Behav., 117: 79-84.
CrossRef | PubMed | Direct Link |
Ahmad, M.A., P. Kapur, R. Khanam, M. Akhtar, G.H. Khan, M.J. Anwar and D. Vohora, 2014. Comparative effect of antihypertensive therapy on blood glucose level in hypertensive patients in an Indian population. Drug Res., 64: 276-280.
CrossRef | Direct Link |
Saraogi, P., D. Vohora, R. Khanam and K.K. Pillai, 2013. Combination therapy of piperine and phenytoin in maximal electroshock induced seizures in mice: Isobolographic and biochemical analysis. Drug Res., 63: 311-318.
CrossRef | Direct Link |
Arora, T., M. Bhowmik, R. Khanam and D. Vohora, 2013. Oxcarbazepine and fluoxetine protect against mouse models of obsessive compulsive disorder through modulation of cortical serotonin and creb pathway. Behav. Brain Res., 247: 146-152.
CrossRef | Direct Link |
Akhtar, M., A.M. Maikiyo, A.K. Najmi, R. Khanam, M. Mujeeb and M. Aqil, 2013. Neuroprotective effects of chloroform and petroleum ether extracts of Nigella sativa seeds in stroke model of rat. J. Pharm. Bioallied Sci., 5: 119-125.
CrossRef | PubMed | Direct Link |
Singh, G., M.U. Khan and R. Khanam, 2012. Protective role of fibrates in cardiac ischemia/reperfusion. J. Adv. Pharm. Technol. Res., 3: 188-192.
CrossRef | PubMed | Direct Link |
Rohilla, A., M.U. Khan and R. Khanam, 2012. Cardioprotective potential of simvastatin in the hyperhomocysteinemic rat heart. J. Adv. Pharm. Technol. Res., 3: 193-198.
CrossRef | PubMed | Direct Link |
Nasir, S.A., A. Sharma, R. Khanam and D. Vohora, 2012. Effect of medroxyprogesterone on development of pentylenetetrazole-induced kindling in mice. Neurosci., 207: 283-287.
CrossRef | PubMed | Direct Link |
Mahmood, D., R. Khanam, K.K. Pillai and M. Akhtar, 2012. Reversal of oxidative stress by histamine H_₃ receptor-ligands in experimental models of schizophrenia. Arzneim.-Forsch., 62: 222-229.
CrossRef | PubMed | Direct Link |
Khanam, R., H. Najfi, M. Akhtar and D. Vohora, 2012. Evaluation of venlafaxine on glucose homeostasis and oxidative stress in diabetic mice. Human Exp. Toxicol., 31: 1244-1250.
CrossRef | PubMed | Direct Link |
Haroon, A., M. Tripathi, R. Khanam and D. Vohora, 2012. Antiepileptic drugs prescription utilization behavior and direct costs of treatment in a national hospital of India. Ann. Indian Acad. Neurol., 15: 289-293.
CrossRef | PubMed | Direct Link |
Danish, M., K. Razia, P.K. Kolappa and A. Mohd, 2012. Protective effects of histamine H3-receptor ligands in schizophrenic behaviors in experimental models. Pharmacol. Rep., 64: 191-204.
CrossRef | PubMed | Direct Link |
Bhowmik, M., R. Khanam and D. Vohora, 2012. Histamine H3 receptor antagonists in relation to epilepsy and neurodegeneration: A systemic consideration of recent progress and perspectives. Br. J. Pharmacol., 167: 1398-1414.
CrossRef | Direct Link |
Anwar, M.J., K.K. Pillai, R. Khanam, M. Akhtar and D. Vohora, 2012. Effect of alprazolam on anxiety and cardiomyopathy induced by doxorubicin in mice. Fundam. Clin. Pharmacol., 26: 356-362.
CrossRef | PubMed | Direct Link |
Akhtar, M., A.M. Maikiyo, R. Khanam, M. Mujeeb, M. Aqil and A.K. Najmi, 2012. Ameliorating effects of two extracts of Nigella sativa in middle cerebral artery occluded rat. J. Pharm. BioAllied Sci., 4: 70-75.
CrossRef | Direct Link |
Pratap, R., K.K. Pillai, R. Khanam, F. Islam and S.J. Ahmad, et al., 2011. Protective effect of irbesartan, an angiotensin II receptor antagonist, alone and in combination with aspirin on middle cerebral artery occlusion model of focal cerebral ischemia in rats. Hum. Exp. Toxicol., 30: 354-362.
CrossRef | Direct Link |
Devi, P.U., A. Manocha, R. Khanam and D. Vohora, 2011. Beneficial interaction between clobenpropit and pyridoxine in prevention of electroshock-induced seizures in mice: Lack of histaminergic mechanisms. Hum. Exp. Toxicol., 30: 84-88.
CrossRef | Direct Link |
Vohora, D., R. Khanam, S.N. Pal and K.K. Pillai, 2010. Effect of combined treatment of thioperamide with some antiepileptic drugs on methionine-sulfoximine induced convulsions in mice. Indian J. Exp. Biol., 48: 858-860.
Vohora, D., P. Saraogi, M.A.Yazdani, M. Bhowmik and R. Khanam, et al., 2010. Recent advances in adjunctive therapy for epilepsy: focus on sodium channel blockers as third-generation antiepileptic drugs. Drugs Today, 46: 265-277.
PubMed | Direct Link |
Rathod, V.P.S., P. Kapoor, K.K. Pillai and R. Khanam, 2010. Assessment of asthma and chronic obstructive pulmonary disorder in relation to reversibility, IgE, eosinophil, and neutrophil count in a University Teaching Hospital in South Delhi, India. J. Pharm. BioAllied Sci., 2: 337-340.
CrossRef | Direct Link |
Mahmood, D., M. Akhtar, D. Vohora and R. Khanam, 2010. Comparison of antinociceptive and antidiabetic effects of sertraline and amitriptyline on streptozotocin-induced diabetic rats. Hum. Exp. Toxicol., 29: 881-886.
PubMed |
Ain, M.R., N. Shahzad, M. Aqil, M.S. Alam and R. Khanam, 2010. Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India J. Pharm. BioAllied Sci., 2: 8-12.
CrossRef | PubMed | Direct Link |
Ansari, M.A., S.J. Ahmad, R. Khanum, and M. Akhtar, 2009. Pharmacological investigation of protective effects of Nigella sativa oil in experimental diabetic neuropathy in rats. Indian J. Pharm. Educ. Res., 43: 166-176.
Khanam, R., A. Faraha, M. Akhtar and D. Vohora, 2008. Interactions of alprazolam and propranolol on depression, anxiety and oxidative stress. Indian J. Pharmacol., 40: 133-133.
Anwar, M.J., K.K. Pillai, R. Khanam, M. Akhtar and D. Vohora, 2008. Effect of alprazolam on anxiety and cardiomyopathy induced by doxorubicin in mice. Indian J. Pharmacol., Vol. 40. .
Akhtar, M., R. Pratap, K.K. Pillai, R. Khanan and F. Islam, 2008. Irbesartan an angiotensin II receptor antagonist protects focal cerebral ischemia in rats. Indian J. Pharmacol., 40: 102-103.
Khanam, R. and K.K. Pillai, 2007. Effect of chronic chromium picolinate in animal models of anxiety and memory. Fundam. Clin. Pharmacol., 21: 531-534.
CrossRef | Direct Link |
Khanam, R. and K.K. Pillai, 2006. Involvement of potassium channels in hypoglycemic effect of sertraline. Indian J. Exp. Biol., 44: 120-122.
Direct Link |
Khanam, R. and K.K. Pillai, 2006. Effect of chromium picolinate on modified forced swimming test in diabetic rats: involvement of serotonergic pathways and potassium channels. Basic Clin. Pharmacol. Toxicol., 98: 155-159.
Direct Link |
Khanam, R. and K.K. Pillai, 2005. Lack of hypo/hyperglycemic effects of reboxetine in diabetic and non-diabetic rats. Fundam. Clin. Pharmacol., 19: 657-659.
PubMed | Direct Link |
Khanam, R., M.A.A. Siddiqui, K.K. Pillai and S.N. Pal, 2002. Effect of various antidepressants and shock-induced convulsions on serotonin levels in brainstem in mice. Adv. Biosci., 21: 29-36.
Siddiqui, M.A.A., A.S. Nazmi, S. Karim, R. Khan, K.K. Pillai and S.N. Pal, 2001. Effect of melatonin and valproate in epilepsy and depression. Indian J. Pharmacol., 33: 378-381.
Razia, K., M.A.A. Siddiqui, K.K. Pillai and S.N. Pal, 2001. Antidepressant Augmentation with Buspirone: effects on seizure threshold and brain serotonin levels in mice. Indian J. Pharmacol., 33: 198-202.
Direct Link |
Siddiqui, M.A.A., A.S. Nazmi, K. Razia, S. Karim and S.N. Pal et al., 1999. Oxidative damage in mice liver induced by sodium valproate: Protection by melatonin. Indian J. Pharmacol., 31: 427-430.
Direct Link |