Mr. Ambuj  Kumar
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Mr. Ambuj Kumar

Research Scientist
University of Florida, USA


Highest Degree
B. Tech. in Bioinformatics from Vellore Institute of Technology University, Tamil Nadu, India

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Biography

Mr. Ambuj Kumar obtained his B. Tech. in Bioinformatics from Vellore Institute of Technology University, Tamil Nadu, India. Currently he is student of PhD at University of Florida, USA. His main area of interest related to Pharmacology and Toxicology, Computational Biology, Biomedical Sciences, and Molecular Sciences. His area of expertise includes Machine Learning, Molecular Dynamics Simulation, Proteomics, Computational Biology, Stististics, Evolution, Phylogeny, Artificial Intelligence, Molecular Modelling and Docking, Chemoinformatics, Protein Thermodynamics, Biological Database, Centrosome, Centromere, Kinetochore, Cell division, Single Nucleotide Polymorphism, Cloud Computing, Cancer, Aneuploidy, Cell Membrane, Receptor Proteins, Gromacs, Genome Sequencing, Gene Expression, Oncogene, Protein Scaffold, and Gene Network. He has published 16 articles in journals as author/co-author.

Area of Interest:

Pharmacology and Toxicology
100%
Computational Biology
62%
Machine Learning
90%
Molecular Dynamics Simulation
75%
Proteomics
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Kumar, A., V. Rajendran, R. sethumadhavan and R. Purohit, 2013. Insight into Nek2A activity regulation and its pharmacological prospects. Egypt. J. Med. Human Genet., 14: 213-219.
    CrossRef  |  Direct Link  |  
  2. Kumar, A., V. Rajendran, R. Sethumadhavan and R. Purohit, 2013. Roadmap to determine the point mutations involved in cardiomyopathy disorder: A bayesian approach. Gene, 519: 34-40.
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Kumar, A., V. Rajendran, R. Sethumadhavan and R. Purohit, 2013. Relationship between a point mutation S97C in CK1δ protein and its affect on ATP-binding affinity. J. Biomol. Struct. Dyn., 10.1080/07391102.2013.770373.
    CrossRef  |  PubMed  |  Direct Link  |  
  4. Kumar, A., V. Rajendran, R. Sethumadhavan and R. Purohit, 2013. Evidence of colorectal cancer-associated mutation in MCAK: A computational report. Cell Biochem. Biophys., 10.1007/s12013-013-9572-1.
    CrossRef  |  PubMed  |  Direct Link  |  
  5. Kumar, A., V. Rajendran, R. Sethumadhavan and R. Purohit, 2013. Computational investigation of cancer-associated molecular mechanism in aurora a (S155R) mutation. Cell Biochem. Biophys., 66: 787-796.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Kumar, A., V. Rajendran, R. Sethumadhavan and R. Purohit, 2013. CEP proteins: The knights of centrosome dynasty. Protoplasma, 10.1007/s00709-013-0488-9.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Kumar, A., B. Kamaraj, R. Sethumadhavan and R. Purohit, 2013. Evolution driven structural changes in CENP-E motor domain. Interdisc. Sci.: Comput. Life Sci., 5: 102-111.
    CrossRef  |  PubMed  |  Direct Link  |  
  8. Kumar, A. and R. Purohit, 2013. Cancer Associated E17K mutation causes rapid conformational drift in AKT1 pleckstrin homology (PH) domain. PLoS ONE, 10.1371/journal.pone.0064364.
    CrossRef  |  PubMed  |  Direct Link  |  
  9. Pandey, A., A. Kumar and R. Purohit, 2012. Sequencing Closterium moniliferum: Future prospects in nuclear waste disposal. Egypt. J. Med. Hum. Genet, 14: 113-115.
    CrossRef  |  Direct Link  |  
  10. Kumar, A., V. Rajendran, R. Sethumadhavan and R. Purohit, 2012. In Silico Prediction of a Disease-Associated STIL Mutant and its Affect on the Recruitment of Centromere Protein J (CENPJ). FEBS Open Bio, 2: 285-293.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Kumar, A., 2012. Computational Prioritization of NsSNP's Involved in causing breast cancer in human. Eur. J. Cancer, 48: S119-S119.
    CrossRef  |  Direct Link  |  
  12. Kumar, A. and R. Purohit, 2012. Computational screening and molecular dynamics simulation of disease associated nsSNPs in CENP-E. Mutat. Res., 738-739: 28-37.
    CrossRef  |  PubMed  |  Direct Link  |  
  13. Kumar, A. and R. Purohit, 2012. Computational Investigation of Pathogenic nsSNPs in CEP63 Protein. Gene, 503: 75-82.
    CrossRef  |  PubMed  |  Direct Link  |  
  14. Kumar A. and R. Purohit, 2012. Computational Centrosomics: An Approach to Understand the Dynamic Behaviour of Centrosome. Gene, 511: 125-126.
    CrossRef  |  PubMed  |  Direct Link  |  
  15. Gulati, G., K.S. Gaonkar, B. Kamraj, A. Kumar and R. Purohit, 2012. Structure based energy calculation to determine the regulation of G protein signalling by RGS and RGS-G protein interaction specificity. Interdiscip. Sci., 4: 173-182.
    CrossRef  |  PubMed  |  Direct Link  |  
  16. Mishra, M. and A. Kumar, 2011. Computational analysis of genetic network involved in pancreatic cancer in human. BMC Bioinformatics, 10.1186/1471-2105-12-S11-A11.
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