Dr. Surajit Ganguly
Senior ScientistHamdard University, India
Highest Degree
Ph.D. in Biochemistry from Jadavpur University, India
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Hamdard University, India
Biography
Dr. Surajit Ganguly is currently working as Team Lead Scientist; Institute of Molecular Medicine, New Delhi, India. He obtained his Ph.D. in Chemical Biology from Jadavpur University, India. He also appointed as Research Associate in Dr. G. Nucifora’s Lab at Cardinal Bernadine Cancer Center, Loyola University Medical center, Maywood, Illinois, USA, Staff Scientist, Adjunct Scientist and Visiting Postdoctoral Fellow at National Institutes of Health, Bethesda, Maryland, USA, and Research Faculty, Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA. He also delivered number of invited lectures at different Institutes. Dr. Surajit received honors includes DHR/ICMR (Government of India) short-term fellowship award, award of Merit for Productivity and Cutting-edge Research U.S. Public Health Services, National Institutes of Health, Maryland, USA, award of Post-Doctoral research fellowship from Fogarty International Center, and award of Research Fellowship from CSIR to conduct Doctoral research in India. He is member of International Society for Neurochemistry, European Pineal and Biological Rhythm Society, former member of the NIH Cognitive Neuroscience Consortium, life member of Indian Society for Chronobiology, and committee member of International Congress on Chronobiology. He is also serving as reviewer for Neurochemical Research, Journal of Circadian Rhythm, and Phytochemistry. Currently he is working on 3 research projects funded by different agencies. He is author and co-author of 18 journal papers.
Area of Interest:
Molecular Sciences
100%
Metabolic Pathways
62%
Neurodevelopmental Diseases
90%
Complex Neurological Disorders
75%
Molecule Interventions
55%
Research Publications in Numbers
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0
Chapters
0
0
Articles
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Abstracts
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Selected Publications
- Ganguly, S. and D.C. Klein, 2017. The Timezyme and Melatonin: Essential Elements of Vertebrate Timekeeping. In: Biological Timekeeping: Clocks, Rhythms and Behaviour, Kumar, V. (Ed.)., Springer, India, pp: 503-20.
- Singh, S., A. Choudhury, P. Gusain, S. Parvez, G. Palit, S. Shukla and S. Ganguly, 2016. Oral acetate supplementation attenuates N-methyl D-aspartate receptor hypofunction-induced behavioral phenotypes accompanied by restoration of acetyl-histone homeostasis. Psychopharmacology, 233: 1257-1268.
CrossRef | Direct Link | - Choudhury, A., S. Singh, G. Palit, S. Shukla and S. Ganguly, 2016. Administration of N-acetylserotonin and melatonin alleviate chronic ketamine-induced behavioural phenotype accompanying BDNF-independent and dependent converging cytoprotective mechanisms in the hippocampus. Behav. Brain Res., 297: 204-212.
CrossRef | Direct Link | - Bose, S., S. Ganguly, S. Kumar and F.R. Boockfor, 2016. A pit-1 binding site adjacent to E-box133 in the rat PRL promoter is necessary for pulsatile gene expression activity. Neurochem. Res., 41: 1390-1400.
CrossRef | Direct Link | - Chatterjee, M., R. Verma, S. Ganguly and G. Palit, 2012. Neurochemical and molecular characterization of ketamine-induced experimental psychosis model in mice. Neuropharmacology, 63: 1161-1171.
CrossRef | Direct Link | - Chatterjee, M., S. Ganguly, M. Srivastava and G. Palit, 2011. Effect of 'chronic' versus 'acute' ketamine administration and its 'withdrawal' effect on behavioural alterations in mice: Implications for experimental psychosis. Behav. Brain Res., 216: 247-254.
CrossRef | Direct Link | - Klein, D.C., M.J. Bailey, D.A. Carter, J.S. Kim and Q. Shi et al., 2010. Pineal function: Impact of microarray analysis. Mol. Cell. Endocrinol., 314: 170-183.
CrossRef | Direct Link | - Bailey, M.J., S.L. Coon, D.A. Carter, A. Humphries, J. Kim and Q. Shi et al., 2009. Night/day changes in pineal expression of >600 genes: Central role of adrenergic/cAMP signaling. J. Biol. Chem., 284: 7606-7622.
CrossRef | Direct Link | - Pavlicek, J., S.L. Coon, S. Ganguly, J.L. Weller, S.A. Hassan, D.L. Sackett and D.C. Klein, 2008. Evidence that proline focuses movement of the floppy loop of arylalkylamine N-acetyltransferase (EC 2.3. 1.87). J. Biol. Chem., 283: 14552-14558.
CrossRef | Direct Link | - Szewczuk, L.M., S.A. Saldanha, S. Ganguly, E.M. Bowers and M. Javoroncov et al., 2007. De novo discovery of serotonin N-acetyltransferase inhibitors. J. Med. Chem., 50: 5330-5338.
CrossRef | Direct Link | - Hwang, Y., S. Ganguly, A.K. Ho, D.C. Klein and P.A. Cole, 2007. Enzymatic and cellular study of a serotonin N-acetyltransferase phosphopantetheine-based prodrug. Bioorg. Med. Chem., 15: 2147-2155.
CrossRef | Direct Link | - Ganguly, S., C. Grodzki, D. Sugden, M. Moller and S. Odom et al., 2007. Neural adrenergic/cyclic AMP regulation of the immunoglobulin E receptor α-subunit expression in the mammalian pinealocyte: A neuroendocrine/immune response link? J. Biol. Chem., 282: 32758-32764.
CrossRef | Direct Link | - Rath, M.F., E. Munoz, S. Ganguly, F. Morin, Q. Shi, D.C. Klein and M. Moller, 2006. Expression of the Otx2 homeobox gene in the developing mammalian brain: Embryonic and adult expression in the pineal gland. J. Neurochem., 97: 556-566.
CrossRef | Direct Link | - Ganguly, S., J.L. Weller, A. Ho, P. Chemineau, B. Malpaux and D.C. Klein, 2005. Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205. Proc. Natl. Acad. Sci. USA., 102: 1222-1227.
PubMed | - Zheng, W., Z. Zhang, S. Ganguly, J.L. Weller, D.C. Klein and P.A. Cole, 2003. Cellular stabilization of the melatonin rhythm enzyme induced by nonhydrolyzable phosphonate incorporation. Nat. Struct. Mol. Biol., 10: 1054-1057.
CrossRef | Direct Link | - Klein, D.C., S. Ganguly, S.L. Coon, Q. Shi and P. Gaildrat et al., 2003. 14-3-3 proteins in pineal photoneuroendocrine transduction: How many roles? J. Neuroendocrinol., 15: 370-377.
CrossRef | - Klein, D.C., S. Ganguly, S. Coon, J.L. Weller, T. Obsil, A. Hickman and F. Dyda, 2002. 14-3-3 proteins and photoneuroendocrine transduction: Role in controlling the daily rhythm in melatonin. Biochem. Soc. Trans., 30: 365-373.
CrossRef | PubMed | Direct Link | - Ganguly, S., S.L. Coon and D.C. Klein, 2002. Control of melatonin synthesis in the mammalian pineal gland: The critical role of serotonin acetylation. Cell Tissue Res., 309: 127-137.
CrossRef | Direct Link | - Obsil, T., R. Ghirlando, D.C. Klein, S. Ganguly and F. Dyda, 2001. Crystal structure of the 14-3-3ζ:serotonin N-acetyltransferase complex: A role for scaffolding in enzyme regulation. Cell, 105: 257-267.
CrossRef | Direct Link | - Ganguly, S., P. Mummaneni, P.J. Steinbach, D.C. Klein and S.L. Coon, 2001. Characterization of the Saccharomyces cerevisiae homolog of the melatonin rhythm enzyme arylalkylamine N-acetyltransferase (EC 2.3. 1.87). J. Biol. Chem., 276: 47239-47247.
CrossRef | Direct Link | - Ganguly, S., J.A. Gastel, J.L. Weller, C. Schwartz and H. Jaffe et al., 2001. Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis. Proc. Natl. Acad. Sci. USA., 98: 8083-8088.
PubMed | - Chakrabarti, S.R., R. Sood, S. Ganguly, S. Bohlander, Z. Shen and G. Nucifora, 1999. Modulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9. Proc. Natl. Acad. Sci. USA., 96: 7467-7472.
PubMed |