Dr. Venugopal P. Menon
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Dr. Venugopal P. Menon

Former Professor and Head
Annamalai University, India

Highest Degree
Ph.D. in Biochemistry from University of Kerala, India

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Biography

Dr. Venugopal P. Menon is currently working as Former Professor & Head, Department of Biochemistry & Biotechnology, Former Dean (Faculty of Science), Former Director of Research at Annamalai University, AnnamalaiNagar, Chidambaram, TamilNadu, India. He obtained his Ph.D. in Biochemistry from University of Kerala, India in 1976. His area of interest focuses on Dietary Factors in Health and Diseases, Role of Different Spices in Hepatic Fibrosis and Colon Cancer, Micronutrient Interventions in Humans, Connective Tissue Metabolism in Health and Diseases, Role of Medicinal Plants their Active Principles and Analogues in Health and Diseases, and Role of Active Principles and Synthetic Analogues as Radioprotectors. He is having 36 years of Post Doctoral experience, and teaching experience. He successfully guided 27 PhD students, and 15 M.Phil students. He is member of 13 professional societies. He is also serving as reviewer for several journals. He also completed 5 national and international projects funded by different agencies. He also delivered 92 guest lectures. He also presented 102 papers at national and international conferences. He has published 222 research articles in journals contributed as author/co-author.

Area of Interest:

Chemistry
100%
Hepatic Fibrosis
62%
Colon Cancer
90%
Micronutrient Interventions
75%
Connective Tissue Metabolism
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Srinivasan, M., K.B. Kalpana, N. Devipriya and V.P. Menon, 2014. Protective effect of lycopene on whole body irradiation induced liver damage of Swiss albino mice: Pathological evaluation. Biomed. Prevent. Nutr., 4: 87-94.
    Direct Link  |  
  2. Sivagami, G., R. Vinothkumar, C.P. Preethy, A. Riyasdeen, M.A. Akbarsha, V.P. Menon and N. Nalini, 2012. Role of hesperetin (a natural flavonoid) and its analogue on apoptosis in HT-29 human colon adenocarcinoma cell line-A comparative study. Food Chem. Toxicol., 50: 660-671.
    Direct Link  |  
  3. Kalpana, K.B., K. Thayalan and V.P. Menon, 2012. Evaluating the radioprotective efficacy of dendrodoine analog against the formation of dicentric aberration frequency in cultured human peripheral blood lymphocytes. Open Nutraceuticals J., 5: 101-106.
    CrossRef  |  Direct Link  |  
  4. Kalpana, K.B., N. Devipriya, M. Srinivasan, P. Vishwanathan, K. Thayalan and V.P. Menon, 2011. Evaluating the radioprotective effect of hesperidin in the liver of Swiss albino mice. Eur. J. Pharmacol., 658: 206-212.
    Direct Link  |  
  5. Sazawal, S., U. Dhingra, P. Dhingra, G. Hiremath and A. Sarkar et al., 2010. Micronutrient fortified milk improves iron status, anemia and growth among children 1-4 years: A double masked, randomized, controlled trial. PloS One, Vol. 5. 10.1371/journal.pone.0012167.
    CrossRef  |  
  6. Sazawal, S., U. Dhingra, G. Hiremath, A. Sarkar and P. Dhingra et al., 2010. Prebiotic and probiotic fortified milk in prevention of morbidities among children: Community-based, randomized, double-blind, controlled trial. PLoS One, Vol. 5. 10.1371/journal.pone.0012164.
    CrossRef  |  
  7. Sazawal, S., U. Dhingra, G. Hiremath, A. Sarkar and P. Dhingra et al., 2010. Effects of bifidobacterium lactis HN019 and prebiotic oligosaccharide added to milk on iron status, anemia and growth among children 1 to 4 years old. J. Pediatr. Gastroenterol. Nutr., 51: 341-346.
    CrossRef  |  Direct Link  |  
  8. Reddy, B.V., J.S. Sundari, E. Balamurugan and V.P. Menon, 2010. Antihyperlipidemic effect of bis-1, 7-(2-hydroxyphenyl)-hepta-1, 6-diene-3, 5-dione, a curcumin analog, on nicotine and streptozotocin treated rats. Mol. Cell. Biochem., 335: 249-254.
    CrossRef  |  PubMed  |  
  9. Rajagopalan, R., S. Sridharana and V.P. Menon, 2010. Hepatoprotective role of bis-demethoxy curcumin analog on the expression of matrix metalloproteinase induced by alcohol and polyunsaturated fatty acid in rats. Toxicol. Mech. Methods, 20: 252-259.
    CrossRef  |  
  10. Pari, L., K. Karthikesan and V.P. Menon, 2010. Comparative and combined effect of chlorogenic acid and tetrahydrocurcumin on antioxidant disparities in chemical induced experimental diabetes. Mol. Cell. Biochem., 341: 109-117.
    CrossRef  |  PubMed  |  
  11. Karthikesan, K., L. Pari and V.P. Menon, 2010. Combined treatment of tetrahydrocurcumin and chlorogenic acid exerts potential antihyperglycemic effect on streptozotocin-nicotinamide-induced diabetic rats. Gen. Physiol. Biophys., 29: 23-30.
    CrossRef  |  Direct Link  |  
  12. Karthikesan, K., L. Pari and V.P. Menon, 2010. Antihyperlipidemic effect of chlorogenic acid and tetrahydrocurcumin in rats subjected to diabetogenic agents. Chemico-Biol. Interact., 188: 643-650.
    CrossRef  |  Direct Link  |  
  13. Kalpana, K.B., N. Devipriya, K. Thayalan and V.P. Menon, 2010. Protection against X-ray radiation-induced cellular damage of human peripheral blood lymphocytes by an aminothiazole derivative of dendrodoine. Chem. Biol. Interact., 186: 267-274.
    CrossRef  |  PubMed  |  Direct Link  |  
  14. Balamurugan, E., B.V. Reddy and V.P. Menon, 2010. Antitumor and antioxidant role of Chrysaora quinquecirrha (sea nettle) nematocyst venom peptide against ehrlich ascites carcinoma in Swiss Albino mice. Mol. Cell. Biochem., 338: 69-76.
    CrossRef  |  PubMed  |  
  15. Srinivasan, M., N. Devipriya, K.B. Kalpana and V.P. Menon, 2009. Lycopene: An antioxidant and radioprotector against γ-radiation-induced cellular damages in cultured human lymphocytes. Toxicology, 262: 43-49.
    CrossRef  |  PubMed  |  Direct Link  |  
  16. Reddy, B.V., J.S. Sundari, E. Balamurugan and V.P. Menon, 2009. Prevention of nicotine and streptozotocin treatment induced circulatory oxidative stress by bis-1, 7-(2-hydroxyphenyl)-hepta-1, 6-diene-3, 5-dione in diabetic rats. Mol. Cell. Biochem., 331: 127-133.
    CrossRef  |  PubMed  |  Direct Link  |  
  17. Manoharan, S., S. Balakrishnan, V.P. Menon, L.M. Alias and A.R. Reena, 2009. Chemopreventive efficacy of curcumin and piperine during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. Singapore Med. J. 50: 139-146.
    Direct Link  |  
  18. Manoharan, S., K. Panjamurthy, V.P. Menon, S. Balakrishnan and L.M. Alias, 2009. Protective effect of Withaferin-A on tumour formation in 7, 12-dimethylbenz [a] anthracene induced oral carcinogenesis in hamsters. Indian J. Exp. Biol., 47: 16-23.
    Direct Link  |  
  19. Kalpana, K.B., N. Devipriya, M. Srinivasan and V.P. Menon, 2009. Investigation of the radioprotective efficacy of hesperidin against γ-radiation induced cellular damage in cultured human peripheral blood lymphocytes. Mutat. Res. Genet. Toxicol. Environ. Mutagene., 676: 54-61.
    CrossRef  |  PubMed  |  Direct Link  |  
  20. Kalpana, K.B., M. Srinivasan and V.P. Menon, 2009. Evaluation of antioxidant activity of hesperidin and its protective effect on H2O2 induced oxidative damage on pBR322 DNA and RBC cellular membrane. Mol. Cell. Biochem., 323: 21-29.
    CrossRef  |  PubMed  |  Direct Link  |  
  21. Dhingra, U., G. Hiremath, V.P. Menon, P. Dhingra, A. Sarkar and S. Sazawal, 2009. Zinc deficiency: Descriptive epidemiology and morbidity among preschool children in Peri-urban population in Delhi, India. J. Health Popul. Nutr., 27: 632-639.
    PubMed  |  
  22. Thirunavukkarasu, M., Z. Han, L. Zhan, S.V. Penumathsa, V.P. Menon and N. Maulik, 2008. Adeno-sh-beta-catenin abolishes ischemic Preconditioning-mediated cardioprotection by downregulation of its target genes VEGF, Bcl-2 and survivin in ischemic rat myocardium. Antioxid. Redox. Signal., 10: 1475-1484.
    CrossRef  |  PubMed  |  
  23. Thirunavukkarasu, M., S. Addya, B. Juhasz, R. Pant, L. Zhan, S. Surrey, G. Maulik, V.P. Menon and N. Maulik, 2008. Heterozygous disruption of Flk-1 receptor leads to myocardial ischaemia reperfusion injury in mice: Application of affymetrix gene chip analysis. J. Cell. Mol. Med., 12: 1284-1302.
    CrossRef  |  
  24. Sudheer, A.R., S. Muthukumaran, N. Devipriya, H. Devaraj and V.P. Menon, 2008. Influence of ferulic acid on nicotine-induced lipid peroxidation, DNA damage and inflammation in experimental rats as compared to N-acetylcysteine. Toxicology, 243: 317-329.
    Direct Link  |  
  25. Ramachandran, S., N. Rajendra Prasad, K.V. Pugalendi and V.P. Menon, 2008. Modulation of UVB-induced oxidative stress by ursolic acid in human blood lymphocytes. Asian J. Biochem., 3: 11-18.
    CrossRef  |  Direct Link  |  
  26. Penumathsa, S.V., S. Koneru, L. Zhan, S. John, V.P. Menon, K. Prasad and N. Maulik, 2008. Secoisolariciresinol diglucoside induces neovascularization-mediated cardioprotection against ischemia-reperfusion injury in hypercholesterolemic myocardium. J. Mol. Cell. Cardiol., 44: 170-179.
    CrossRef  |  Direct Link  |  
  27. Penumathsa, S.V., M. Thirunavukkarasu, L. Zhan, G. Maulik, V.P. Menon, D. Bagchi and N. Maulik, 2008. Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium. J. Cell. Mol. Med., 12: 2350-2361.
    CrossRef  |  
  28. Panjamurthy, K., S. Manoharan, V.P. Menon, M.R. Nirmal and N. Senthil, 2008. Protective role of withaferin-A on 7,12-dimethylbenz(a)anthracene-induced genotoxicity in bone marrow of Syrian golden hamsters. J. Biochem. Mol. Toxicol., 22: 251-258.
    CrossRef  |  PubMed  |  
  29. Muthukumaran, S., A.R. Sudheer, V.P. Menon and N. Nalini, 2008. Protective effect of quercetin on nicotine-induced prooxidant and antioxidant imbalance and DNA damage in wistar rats. Toxicology, 243: 207-215.
    CrossRef  |  PubMed  |  Direct Link  |  
  30. Muthukumaran, S., A.R. Sudheer, N. Nalini and V.P. Menon, 2008. Effect of quercetin on nicotine-induced biochemical changes and DNA damage in rat peripheral blood lymphocytes. Redox Rep., 13: 217-224.
    CrossRef  |  Direct Link  |  
  31. Kalpana, K.B., M. Srinivasan and V.P. Menon, 2008. Antioxidant potential of aminothiazole derivative and its protective effect on H2O2-induced oxidative damage on pBR322 DNA and RBC cellular membrane. Mol. Cell. Biochem., 314: 95-103.
    CrossRef  |  Direct Link  |  
  32. Juhasz, B., M. Thirunavukkarasu, R. Pant, L. Zhan and S.V. Penumathsa et al., 2008. Bromelain induces cardioprotection against Ischemia-reperfusion injury through Akt/FOXO pathway in rat myocardium. Am. J. Physiol. Heart Circulat. Physiol., 294: H1365-H1370.
    CrossRef  |  
  33. Devipriya, N., A.R. Sudheer, P. Vishwanathan and V.P. Menon, 2008. Modulatory potential of ellagic acid, a natural plant polyphenol on altered lipid profile and lipid peroxidation status during alcohol-induced toxicity: A pathohistological study. J. Biochem. Mol. Toxicol., 22: 101-112.
    CrossRef  |  Direct Link  |  
  34. Devipriya, N., A.R. Sudheer, M. Srinivasan and V.P. Menon, 2008. Quercetin ameliorates gamma radiation-induced DNA damage and biochemical changes in human peripheral blood lymphocytes. Mutat. Res., 654: 1-7.
    Direct Link  |  
  35. Devipriya, N., A.R. Sudheer and V.P. Menon, 2008. Caffeic acid protects human peripheral blood lymphocytes against gamma radiation-induced cellular damage. J. Biochem. Mol. Toxicol., 22: 175-186.
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  36. De, S., S. Adhikari, J. Tilak-Jain, V.P. Menon and T.P.A. Devasagayam, 2008. Antioxidant activity of an aminothiazole compound: Possible mechanisms. Chem. Biol. Interact., 173: 215-223.
    Direct Link  |  
  37. Balakrishnan, S., V.P. Menon and S. Manoharan, 2008. Ferulic acid inhibits 7, 12-dimethylbenz [α] anthracene-induced hamster buccal pouch carcinogenesis. J. Med Food, 11: 693-700.
    CrossRef  |  Direct Link  |  
  38. Balakrishnan, S., S. Manoharan, A.L. Mary, K. Panjamurthy, L. Vellaichamy and V.P. Menon, 2008. Protective effects of curcumin and ferulic acid on circadian pattern of lipid peroxidation and antioxidants in 7,12-dimethylbenz[a] anthracene-induced oral carcinogenesis. J. Cell. Tissue Res., 8: 1525-1530.
    Direct Link  |  
  39. Balakrishnan, S., L. Vellaichamy, V.P. Menon and S. Manoharan, 2008. Antigenotoxic effects of curcumin and piperine alone or in combination against 7,12-dimethylbenz(a)anthracene induced genotoxicity in bone marrow of golden Syrian hamsters. Toxicol. Mech. Methods, 18: 691-696.
    Direct Link  |  
  40. Balaji, T., M. Ramanathan, M. Srinivasan and V.P. Menon, 2008. Distribution of cyclooxygenase-1 and cyclooxygenase-2 in the mouse seminal vesicle. J. Applied Biomed., 6: 97-104.
    Direct Link  |  
  41. Thirunavukkarasu, M., B. Juhasz, L. Zhan, V.P. Menon, A. Tosaki, H. Otani and N. Maulik, 2007. VEGFR1 (Flt-1+/−) gene knockout leads to the disruption of VEGF-mediated signaling through the nitric oxide/heme oxygenase pathway in ischemic preconditioned myocardium. Free Radical Biol. Med., 42: 1487-1495.
    PubMed  |  Direct Link  |  
  42. Sudheer, A.R., S. Muthukumaran, N. Devipriya and V.P. Menon, 2007. Ellagic acid, a natural polyphenol protects rat peripheral blood lymphocytes against nicotine-induced cellular and DNA damage in vitro: With the comparison of N-acetylcysteine. Toxicology, 230: 11-21.
    CrossRef  |  Direct Link  |  
  43. Sudheer, A.R., S. Muthukumaran, C. Kalpana, M. Srinivasan and V.P. Menon, 2007. Protective effect of ferulic acid on nicotine-induced DNA damage and cellular changes in cultured rat peripheral blood lymphocytes: A comparison with N-acetylcysteine. Toxicol. In Vitro, 21: 576-585.
    CrossRef  |  
  44. Srinivasana, M., A.R. Sudheera, K.R. Pillaib, P.R. Kumarc, P.R. Sudhakarand and V.P. Menon, 2007. Lycopene as a natural protector against γ-radiation induced DNA damage, lipid peroxidation and antioxidant status in primary culture of isolated rat hepatocytes in vitro. Biochim. Biophys. Acta-Gen. Subjects, 1770: 659-665.
    CrossRef  |  Direct Link  |  
  45. Srinivasan, M., A.R. Sudheer, K.R. Pillai, P.R. Kumar, P.R. Sudhakaran and V.P. Menon, 2007. Modulatory effects of curcumin on γ-radiation-induced cellular damage in primary culture of isolated rat hepatocytes. Environ. Toxicol. Pharmacol., 24: 98-105.
    Direct Link  |  
  46. Srinivasan, M., A.R. Sudheer and V.P. Menon, 2007. Ferulic acid: Therapeutic potential through its antioxidant property. J. Clin. Biochem. Nutr., 40: 92-100.
    CrossRef  |  Direct Link  |  
  47. Sazawal, S., U. Dhingra, S. Deb, M.K. Bhan, V.P. Menon and R.E. Black, 2007. Effect of zinc added to multivitamin supplementation containing Low-dose Vitamin A on plasma retinol level in children: A Double-blind randomized, controlled trial. J. Health, Popul. Nutr., 25: 62-66.
    Direct Link  |  
  48. Sazawal, S., U. Dhingra, P. Dhingra, G. Hiremath, J. Kumar, A. Sarkar, V.P. Menon and R.E. Black, 2007. Effects of fortified milk on morbidity in young children in north India: Community based, randomised, double masked placebo controlled trial. BMJ., Vol. 334. 10.1136/bmj.39035.482396.55.
    CrossRef  |  
  49. Prasad, N.R., S. Ramachandran, K.V. Pugalendi and V.P. Menon, 2007. Ferulic acid inhibits UV-B-induced oxidative stress in human lymphocytes. Nutr. Res., 27: 559-564.
    Direct Link  |  
  50. Penumathsa, S.V., M. Thirunavukkarasu, S. Koneru, B. Juhasz and L. Zhan et al., 2007. Statin and resveratrol in combination induces cardioprotection against myocardial infarction in hypercholesterolemic rat. J. Mol. Cell. Cardiol., 42: 508-516.
    Direct Link  |  
  51. Kode, A., R. Rajagopalan, S.V. Penumastha and V.P. Menon, 2007. Role of an aminothiazole derivative on ethanol-induced toxicity. Toxicol. Mech. Methods, 17: 33-40.
    Direct Link  |  
  52. Kalpana, C., A.R. Sudheer, K.N. Rajasekharan and V.P. Menon, 2007. Comparative effects of curcumin and its synthetic analogue on tissue lipid peroxidation and antioxidant status during nicotine-induced toxicity. Singapore Med. J., 48: 124-130.
    Direct Link  |  
  53. Dhingra, P., S. Sazawal, V.P. Menon, U. Dhingra and R.E. Black, 2007. Validation of visual estimation of portion size consumed as a method for estimating food intake by young Indian children. J. Health Popul. Nutr., 25: 112-115.
    Direct Link  |  
  54. Devipriya, N., M. Srinivasan, A.R. Sudheer and V.P. Menon, 2007. Effect of ellagic acid, a natural polyphenol, on alcohol-induced prooxidant and antioxidant imbalance: A drug dose dependent study. Singapore Med. J., 48: 311-318.
    PubMed  |  Direct Link  |  
  55. Devipriya, N., A.R. Sudheer and V.P. Menon, 2007. Dose-response effect of ellagic acid on circulatory antioxidants and lipids during alcohol-induced toxicity in experimental rats. Fundam. Clin. Pharmacol., 21: 621-630.
    CrossRef  |  Direct Link  |  
  56. Balakrishnan, A. and V.P. Menon, 2007. Protective effect of hesperidin on nicotine induced toxicity in rats. Indian J. Exp. Biol., 45: 194-202.
    PubMed  |  Direct Link  |  
  57. Balakrishnan, A. and V.P. Menon, 2007. Effect of hesperidin on matrix metalloproteinases and antioxidant status during nicotine-induced toxicity. Toxicology, 238: 90-98.
    CrossRef  |  Direct Link  |  
  58. Balakrishnan, A. and V.P. Menon, 2007. Antioxidant properties of hesperidin in nicotine-induced lung toxicity. Fundam. Clin. Pharmacol., 21: 535-546.
    CrossRef  |  
  59. Balakrishnan, A. adn V.P. Menon, 2007. Effect of hesperidin on nicotine toxicity and histopathological studies. Toxicol. Mech. Methods, 17: 233-239.
    Direct Link  |  
  60. Balaji, T., M. Ramanathan and V.P. Menon, 2007. Localization of cyclooxygenase-2 in mice vas deferens and its effects on fertility upon suppression using nimesulide: A preferential cyclooxygenase-2 inhibitor. Toxicology, 234: 135-144.
    Direct Link  |  
  61. Srinivasan, M., N.R. Prasad and V.P. Menon, 2006. Protective effect of curcumin on γ-radiation induced DNA damage and lipid peroxidation in cultured human lymphocytes. Mutat. Res./Genet. Toxicol. Environ. Mutagen., 611: 96-103.
    CrossRef  |  PubMed  |  Direct Link  |  
  62. Srinivasan, M., A.R. Sudheer, K.R. Pillai, P.R. Kumar, P.R. Sudhakaran and V.P. Menon, 2006. Influence of ferulic acid on γ-radiation induced DNA damage, lipid peroxidation and antioxidant status in primary culture of isolated rat hepatocytes. Toxicology, 228: 249-258.
    Direct Link  |  
  63. Sarkar, A., A. Dutta, U. Dhingra, P. Dhingra and P. Verma et al., 2006. Development and use of behavior and social interaction software installed on Palm handheld for observation of a child's social interactions with the environment. Behav. Res. Methods, 38: 407-415.
    CrossRef  |  Direct Link  |  
  64. Prasad, N.R., M. Srinivasan, K.V. Pugalendi and V.P. Menon, 2006. Protective effect of ferulic acid on γ-radiation-induced micronuclei, dicentric aberration and lipid peroxidation in human lymphocytes. Mutat. Res., 603: 129-134.
    Direct Link  |  
  65. Penumathsa, S.V., A. Kode, R. Rajagopalan and V.P. Menon, 2006. Changes in activities of MMP in alcohol and thermally oxidized sunflower oil-induced liver damage: NAC antioxidant therapy. Toxicol. Mech. Methods, 16: 267-274.
    Direct Link  |  
  66. Nalini, N., V. Manju and V.P. Menon, 2006. Effect of spices on lipid metabolism in 1, 2-dimethylhydrazine-induced rat colon carcinogenesis. J. Med. Food, 9: 237-245.
    CrossRef  |  Direct Link  |  
  67. Devasena, T., V.P. Menon and K.N. Rajasekharan, 2006. Prevention of 1, 2-dimethylhydrazine-induced circulatory oxidative stress by bis-1, 7-(2-hydroxyphenyl)-hepta-1, 6-diene-3, 5-dione during colon carcinogenesis. Pharmacol. Rep., 58: 229-235.
    Direct Link  |  
  68. Balasubashini, M.S., S. Karthigayan, S.T. Somasundaram, T. Balasubramanian, V. Viswanathan, P. Raveendran and V.P. Menon, 2006. Fish venom (Pterios volitans) peptide reduces tumor burden and ameliorates oxidative stress in Ehrlich's ascites carcinoma xenografted mice. Bioorgan. Med. Chem. Lett., 16: 6219-6225.
    Direct Link  |  
  69. Balasubashini, M.S., S. Karthigayan, S.T. Somasundaram, T. Balasubramanian, R. Rukkumani and V.P. Menon, 2006. FV peptide induces apoptosis in HEp 2 and HeLa cells: An insight into the mechanism of induction. J. Carcinogenesis, Vol. 5. 10.1186/1477-3163-5-27.
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  70. Balasubashini, M.S., S. Karthigayan, S.T. Somasundaram, T. Balasubramanian, P. Viswanathan and V.P. Menon, 2006. In vivo and in vitro characterization of the biochemical and pathological changes induced by lionfish (Pterios volitans) venom in mice. Toxicol. Mech. Methods, 16: 525-531.
    Direct Link  |  
  71. Aruna, K., R. Rukkumani, P.S. Varma and V.P. Menon, 2006. Role of Cuminum cyminum on ethanol and preheated sunflower oil induced lipid peroxidation. J. Herbs Spices Med. Plants, 11: 103-114.
    CrossRef  |  
  72. Sudheer, A,R., C. Kalpana, M. Srinivasan and V.P. Menon, 2005. Ferulic acid modulates altered lipid profiles and prooxidant/antioxidant status in circulation during nicotine-induced toxicity: A dose-dependent study. Toxicol. Mechanisms Methods, 15: 375-381.
    CrossRef  |  Direct Link  |  
  73. Srinivasan, M., R. Rukkumani, A. Ram Sudheer and V.P. Menon. 2005. Ferulic acid, a natural protector against carbon tetrachloride-induced toxicity. Fundam Clin. Pharmacol., 19: 491-496.
    CrossRef  |  PubMed  |  
  74. Rukkumani, R., K. Aruna, P.S. Varma, P. Viswanathan, K.N. Rajasekaran and V.P. Menon, 2005. Protective role of a novel curcuminoid on alcohol and PUFA-induced hyperlipidemia. Toxicol. Mech. Methods, 15: 227-234.
    Direct Link  |  
  75. Prasad, N.R., V.P. Menon, V. Vasudev and K.V. Pugalendi, 2005. Radioprotective effect of sesamol on γ-radiation induced DNA damage, lipid peroxidation and antioxidants levels in cultured human lymphocytes. Toxicology, 209: 225-235.
    Direct Link  |  
  76. Prasad, N.R., T. Mahesh, V.P. Menon, R.K. Jeevanram and K.V. Pugalendi, 2005. Photoprotective effect of sesamol on UVB-radiation induced oxidative stress in human blood lymphocytes in vitro. Environ. Toxicol. Pharmacol., 20: 1-5.
    CrossRef  |  Direct Link  |  
  77. Mahesh, T., M.S. Balasubashini and V.P. Menon, 2005. Effect of photo-irradiated curcumin treatment against oxidative stress in streptozotocin-induced diabetic rats. J. Med. Food, 8: 251-255.
    PubMed  |  
  78. Kode, A., R. Rajagopalan, S.V. Penumathsa and V.P. Menon, 2005. Effect of ethanol and thermally oxidized sunflower oil ingestion on phospholipid fatty acid composition of rat liver: Protective role of Cuminum cyminum L. Ann. Nutr. Metab., 49: 300-303.
    PubMed  |  
  79. Kamalakkannan, N., R. Rukkumani, P.S. Varma, P. Viswanathan, K.N. Rajasekharan and V.P. Menon, 2005. Comparative effects of curcumin and an analogue of curcumin in carbon tetrachloride-induced hepatotoxicity in rats. Basic Clin. Pharm. Toxicol., 97: 15-21.
    CrossRef  |  PubMed  |  Direct Link  |  
  80. Aruna, K., R. Rukkumani, P.S. Varma and V.P. Menon, 2005. Therapeutic role of Cuminum cyminum on ethanol and thermally oxidized sunflower oil induced toxicity. Phytother. Res., 19: 416-421.
    CrossRef  |  
  81. Varma, P.S., K. Aruna, R. Rukkumani, P. Viswanathan and V.P. Menon, 2004. Protective effect of n-acetyl cysteine treatment on alcohol-and heated sunflower oil induced hyperlipidaemia. Alcohol. Res., 9: 266-272.
  82. Varma, P.S., K. Aruna, R. Rukkumani and V.P. Menon, 2004. Alcohol and thermally oxidized pufa induced oxidative stress: Role of N-acetyl cysteine. Italian J. Biochem., 53: 10-15.
    Direct Link  |  
  83. Sazawal, S., U. Dhingra, A. Sarkar, P. Dhingra and S. Deb et al., 2004. Efficacy of milk fortified with a probiotic Bifidobacterium lactis HN019 (DR-10TM) and prebiotic galacto-oligosaccharides in prevention of morbidity-a community based double masked randomized trail. Pediatr. Gastroenterol. Hepatol. Nutr., 88: 371-374.
    Direct Link  |  
  84. Sarkar, A., S. Sazawal, U. Dhingra, P. Dhingra and M. Sood et al., 2004. Effect of fortification of milk with probiotic bifidobacterium Lactis HN019 (DR-10TM) and Galacto-oligosaccharides on anemia, growth and development in children aged 1-4 years-a double masked randomized trail. Pediatr. Gastroenterol. Hepatol. Nutr., 88: 59-63.
  85. Rukkumani, R., K. Aruna, P.S. Varma, K.N. Rajasekaran and V.P. Menon, 2004. Comparative effects of curcumin and an analog of curcumin on alcohol and PUFA induced oxidative stress. J. Pharm. Pharmacol. Sci., 7: 274-283.
    Direct Link  |  
  86. Rukkumani, R., K. Aruna, P.S. Varma and V.P. Menon, 2004. Ferulic-acid, a natural phenolic antioxidant modulates altered lipid profiles during alcohol and thermally oxidized sunflower oil induced toxicity. J. Nutraceuticals Funct. Med. Foods, 4: 119-132.
    Direct Link  |  
  87. Rukkumani, R., K. Aruna, P.S. Varma and V.P. Menon, 2004. Curcumin influences hepatic expression patterns of matrix metalloproteinases in liver toxicity. Ital. J. Biochem., 53: 61-66.
    Direct Link  |  
  88. Rukkumani, R., K. Aruna, P. Suresh Varma and V.P. Menon, 2004. Hepatoprotective role of ferulic acid: A dose-dependent study. J. Med. Food, 7: 456-461.
    CrossRef  |  
  89. Prince, P.S.M., N. Kamalakkannan and V.P. Menon, 2004. Restoration of antioxidants by ethanolic Tinospora cordifolia in alloxan-induced diabetic Wistar rats. Acta Pol. Pharm., 61: 283-287.
    PubMed  |  
  90. Prince, P.S.M., N. Kamalakkannan and V.P. Menon, 2004. Antidiabetic and antihyperlipidaemic effect of alcoholic Syzigium cumini seeds in alloxan induced diabetic albino rats. J. Ethnopharmacol., 91: 209-213.
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  91. Nalini, N., V. Manju and V.P. Menon, 2004. Effect of coconut cake on the bacterial enzyme activity in 1, 2-dimethyl hydrazine induced colon cancer. Clin. Chim. Acta, 342: 203-210.
    Direct Link  |  
  92. Maureen, M., S. Sunil, K. Sonu, J. Kumar and V. Menon, 2004. Cognitive and motor development among small-for-gestational-age infants: Impact of zinc supplementation, birth weight and caregiving practices. J. Pediatr., 113: 1297-1304.
    Direct Link  |  
  93. Marwah, D., S. Sazawal, U. Dhingra, P. Verma and S. Deb et al., 2004. Efficacy of micronutrient fortification of milk in prevention of childhood morbidity in children 1-3 years of age-a community based double masked randomized trail. Pediatr. Gastroenterol. Hepatol. Nutr., 88: 367-370.
  94. Mahesh, T., M.M.S. Balasubashini and V.P. Menon, 2004. Photo-irradiated curcumin supplementation in Streptozotocin-induced diabetic rats: Effect on lipid peroxidation. Therapie, 59: 639-644.
    CrossRef  |  
  95. Mahesh, T. and V.P. Menon, 2004. Quercetin allievates oxidative stress in streptozotocin‐induced diabetic rats. Phytother. Res., 18: 123-127.
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  96. Kode, A., R. Rajagopalan, S.V. Penumathsa and V.P. Menon, 2004. Influence of a thiazole derivative on ethanol and thermally oxidized sunflower oil-induced oxidative stress. Fundam. Clin. Pharmacol., 18: 565-571.
    CrossRef  |  
  97. Kalpana, C. and V.P. Menon, 2004. Modulatory effects of curcumin on lipid peroxidation and antioxidant status during nicotine-induced toxicity. Pol. J. Pharmacol., 56: 581-586.
  98. Kalpana, C. and V.P. Menon, 2004. Inhibition of nicotine-induced toxicity by curcumin and curcumin analog: A comparative study. J. Med. Food, 7: 467-471.
    CrossRef  |  Direct Link  |  
  99. Kalpana, C. and V.P. Menon, 2004. Curcumin ameliorates oxidative stress during nicotine-induced lung toxicity in Wistar rats. Ital. J. Biochem., 53: 82-86.
    Direct Link  |  
  100. Juyal, R., M. Osmamy, R.E. Black, U. Dhingra and A. Sarkar et al., 2004. Efficacy of micronutrient fortification of milk on morbidity in pre-school children and growth-a double blind randomised controlled trial. Asia Pac. J. Clin. Nutr., 13: 137-142.
  101. Jaya, D.S. and V.P. Menon, 2004. Study on the changes in glycolipid levels during alcoholism and paracetamol toxicity in rats. Toxicol. Int., 11: 55-62.
    Direct Link  |  
  102. Dhingra, P., V.P. Menon, S. Sazawal, U. Dhingra and D. Marwah et al., 2004. Effect of fortification of milk with zinc and iron along with vitamins C, E, A and selenium on growth, iron status and development in preschool children-a community based double-masked randomized trail. Pediatr. Gastroenterol. Hepatol. Nutr., 88: 53-57.
  103. Balasubashini, M.S., R. Rukkumani, P. Viswanathan and V.P. Menon, 2004. Ferulic acid alleviates lipid peroxidation in diabetic rats. Phytother. Res., 18: 310-314.
    CrossRef  |  
  104. Aruna, K., R. Rukkumani, P. Sureshvarma and V.P. Menon, 2004. Role of an aminothiazole derivative on ethanol-and thermally oxidized sunflower oil-induced toxicity. Polish J. Pharmacol., 56: 233-240.
    Direct Link  |  
  105. Stanely, P., M. Prince and V.P. Menon, 2003. Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats. Phytother. Res., 17: 410-413.
    CrossRef  |  Direct Link  |  
  106. Srivivasan, A., V.P. Menon, V. Periaswamy and K.N. Rajasekaran, 2003. Protection of pancreatic beta-cell by the potential antioxidant bis-o-hydroxycinnamoyl methane, analogue of natural curcuminoid in experimental diabetes. J. Pharm. Pharm. Sci., 6: 327-333.
    PubMed  |  Direct Link  |  
  107. Rukkumani, R., M.S. Balasubashini and V.P. Menon, 2003. Protective effects of curcumin and photo-irradiated curcumin on circulatory lipids and lipid peroxidation products in alcohol and polyunsaturated fatty acid-induced toxicity. Phytother. Res., 17: 925-929.
    CrossRef  |  PubMed  |  Direct Link  |  
  108. Rukkumani, R. and V.P. Menon, 2003. Protective role of photo-irradiated curcumin on alcohol and thermally oxidised PUFA induced hyperlipidemia. Curr. Adv. Atheroscler. Res., 5: 145-156.
  109. Prince, P.S.M., N. Kamalakkannan and V.P. Menon, 2003. Syzigium cumini seed extracts reduce tissue damage in diabetic rat brain. J. Ethnopharmacol., 84: 205-209.
    Direct Link  |  
  110. Mahesh, T., M. Balasubashini and V.P. Menon, 2003. Ameliorative effect of irradiated curcumin and ferulic acid in experimental diabetes. Curr. Adv. Atheroscler. Res., 5: 184-197.
  111. Devasena, T., K.N. Rajasekaran, G. Gunasekaran, P. Viswanathan and V.P. Menon, 2003. Anticarcinogenic effect of bis-1, 7-(2-hydroxyphenyl)-hepta-1, 6-diene-3, 5-dione a curcumin analog on DMH-induced colon cancer model. Pharmacol. Res., 47: 133-140.
    Direct Link  |  
  112. Devasena, T., G. Gunasekaran, P. Viswanathan and V.P. Menon, 2003. Chemoprevention of 1,2-dimethylhydrozine-induced colon carcinogenesis by seeds of Trigonella foenum graecum L. Biol. Bratislava, 58: 357-364.
  113. Devasena, T. and V.P. Menon, 2003. Fenugreek affects the activity of beta-glucuronidase and mucinase in the colon. Phytother. Res., 17: 1088-1091.
    CrossRef  |  Direct Link  |  
  114. Balasubashini, M.S., R. Rukkumani and V.P. Menon, 2003. Protective effects of ferulic acid on hyperlipidemic diabetic rats. Acta Diabetol., 40: 118-122.
    CrossRef  |  PubMed  |  
  115. Rukkumani, R., M.S. Balasubashini, P. Vishwanathan and V.P. Menon, 2002. Comparative effects of curcumin and photo-irradiated curcumin on alcohol-and polyunsaturated fatty acid-induced hyperlipidemia. Pharmacol. Res., 46: 257-264.
    Direct Link  |  
  116. Rajakrishnan, V., S.J. Shiney, P.R. Sudhakaran and V.P. Menon, 2002. Effect of curcumin on ethanol-induced stress on mononuclear cells. Phytother. Res., 16: 171-173.
    CrossRef  |  
  117. Rajakrishnan, V. and V.P. Menon, 2002. Effect of curcumin on carbohydrate moieties of glycoprotein in alcohol-induced hepatotoxicity. J. Herbs Spices Med. Plants, 9: 19-28.
    CrossRef  |  Direct Link  |  
  118. Devasena, T., K.N. Rajasekaran and V.P. Menon, 2002. Bis-1, 7-(2-hydroxyphenyl)-hepta-1, 6-diene-3, 5-dione (a curcumin analog) ameliorates DMH-induced hepatic oxidative stress during colon carcinogenesis. Pharmacol. Res., 46: 39-45.
    Direct Link  |  
  119. Devasena, T. and V.P. Menon, 2002. Enhancement of circulatory antioxidants by fenugreek during 1, 2-dimethylhydrazine-induced rat colon carcinogenesis. J. Biochem. Mol. Biol. Biophys., 6: 289-292.
  120. Aruna, K., C. Kalpana, P. Viswanathan and V.P. Menon, 2002. Toxic effects of sunflower oil on ethanol treated rats. Hepatol. Res., 24: 125-135.
    Direct Link  |  
  121. Sazawal, S., R.E. Black, V.P. Menon, P. Dinghra, L.E. Caulfield, U. Dhingra and A. Bagati, 2001. Zinc supplementation in infants born small for gestational age reduces mortality: A prospective, randomized, controlled trial. Pediatrics, 108: 1280-1286.
  122. Prince, P.S.M. and V.P. Menon, 2001. Antioxidant action of Tinospora cordifolia root extract in alloxan diabetic rats. Phytother. Res., 15: 213-218.
    CrossRef  |  PubMed  |  Direct Link  |  
  123. Manoj, G., B.S.H. Thampi, S. Leelamma and P.V.G. Menon, 2001. Effect of dietary fiber on the activity of intestinal and fecal beta-glucuronidase activity during 1, 2-dimethylhydrazine induced colon carcinogenesis. Plant Foods Human Nutr., 56: 13-21.
    CrossRef  |  
  124. Gireesh, T., A. Jayadeep, K.N. Rajasekharan, V.P. Menon and M. Vairamany et al., 2001. Production of deuterated β-carotene by metabolic labelling of Spirulina platensis. Biotechnol. Lett., 23: 447-449.
    CrossRef  |  
  125. Akrishnan, V.R. and V.P. Menon, 2001. Potential role of antioxidants during ethanol induced changes in the fatty acid composition and arachidonic acid metabolites in male Wistar rats. Cell Biol. Toxicol., 17: 11-22.
    CrossRef  |  PubMed  |  

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