Dr. Rajeev  Mishra

Dr. Rajeev Mishra

Assistant Professor
Manipal University Jaipur Rajasthan, India

Highest Degree
Ph.D. in Life Science from Central Drug Research Institute, India

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Area of Interest:

Biomedical Sciences
Cancer Science
Food Toxicology
Biological Chemistry

Selected Publications

  1. Mishra, R., S. Haldar, V. Placencio, A. Madhav and K. Rohena-Rivera et al., 2018. Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming. J. Clin. Investig., 128: 4472-4484.
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  2. Madhav, A., A. Andres, F. Duong, R. Mishra, S. Haldar, Z. Liu, et al., 2018. Antagonizing CD105 enhances radiation sensitivity in prostate cancer. Oncogene, 37: 4385-4397.
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  3. Kato, M., V. Placencio, A. Madhav, S. Haldar and K. Rohena-Rivera et al., 2018. Heterogeneous cancer-associated fibroblast population potentiates neuroendocrine differentiation and castrate resistance in a CD105-dependent manner. Oncogene, 38: 716-730.
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  4. Tripathi, M., S. Nandana, S. Billet, K.A. Cavassani and R. Mishra et al., 2017. Modulation of cabozantinib efficacy by the prostate tumor microenvironment. Oncotarget, 8: 87891-87902.
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  5. Nandana, S., M. Tripathi, P. Duan, C.Y. Chu and R. Mishra et al., 2017. Bone metastasis of prostate cancer can be therapeutically targeted at the TBX2-WNT signaling axis. Cancer Res., 77: 1331-1344.
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  6. Minciacchi, V.R., C. Spinelli, M. Reis-Sobreiro, L. Cavallini and S. You et al., 2017. MYC mediates large oncosome-induced fibroblast reprogramming in prostate cancer. Cancer Res., 77: 2306-2317.
  7. Haldar, S., C. Dru, R. Mishra, M. Tripathi and F. Duong et al., 2016. Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis. Scient. Rep., Vol. 6. .
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  8. Mishra, R., T. Watanabe, M.T. Kimura, N. Koshikawa and M. Ikeda et al., 2015. Identification of a novel E‐box binding PI polyamide inhibiting MYC‐driven cell‐proliferation. Cancer Sci., 106: 421-429.
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  9. Haldar, S., C. Dru, D. Choudhury, R. Mishra and A. Fernandez et al., 2015. Inflammation and pyroptosis mediate muscle expansion in an interleukin-1β (IL-1β)-dependent manner. J. Biol. Chem., 290: 6574-6583.
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  10. Banerjee, J., R. Mishra, X. Li, R.S. Jackson, A. Sharma and N.A. Bhowmick, 2014. A reciprocal role of prostate cancer on stromal DNA damage. Oncogene, 33: 4924-4931.
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  11. Qi, J., M. Tripathi, R. Mishra, N. Sahgal and L. Fazil et al., 2013. The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity. Cancer Cell, 23: 332-346.
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  12. Kawashima, H., K. Sugito, S. Yoshizawa, S. Uekusa and T. Furuya et al., 2012. DNA hypomethylation at the ZNF206-exon 5 CpG island associated with neuronal differentiation in mice and development of neuroblastoma in humans. Int. J. Oncol., 40: 31-39.
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  13. Mishra, R., S. Bhadauria, P.K. Murthy and P.S.R. Murthy, 2011. Glycine soya diet synergistically enhances the suppressive effect of tamoxifen and inhibits tamoxifen-promoted hepatocarcinogenesis in 7, 12-dimethylbenz [α] anthracene-induced rat mammary tumor model. Food Chem. Toxicol., 49: 434-440.
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  14. Wang, X., H. Nagase, T. Watanabe, H. Nobusue and T. Suzuki et al., 2010. Inhibition of MMP‐9 transcription and suppression of tumor metastasis by pyrrole‐imidazole polyamide. Cancer Sci., 101: 759-766.
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  15. Mishra, R., A. Tiwari, S. Bhadauria, J. Mishra, P.K. Murthy and P.S.R. Murthy, 2010. Therapeutic effect of centchroman alone and in combination with glycine soya on 7, 12-dimethylbenz [α] anthracene-induced breast tumor in rat. Food Chem. Toxicol., 48: 1587-1591.
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  16. Cao, S., R. Mishra, S. Pilla, S. Tripathi and M.K. Pandey et al., 2010. Novel chitosan/gold-MPA nanocomposite for sequence-specific oligonucleotide detection. Carbohydr. Polym., 82: 189-194.
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  17. Bhadauria, S., R. Mishra, R. Kanchan, C. Tripathi, A. Srivastava, A. Tiwari and S. Sharma, 2010. Isoniazid-induced apoptosis in HepG2 cells: generation of oxidative stress and Bcl-2 down-regulation. Toxicol. Mech. Methods, 20: 242-251.
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  18. Srivastava, A.K., R. Sharma, R. Mishra, A.K. Balapure, P.S. Murthy and G. Panda, 2006. Substituted phenanthrenes with basic amino side chains: A new series of anti-breast cancer agents. Bioorgan. Med. Chem., 14: 1497-1505.
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