Dr. Ayyakkannu Purushothaman
Assistant Professor and HeadMohamed Sathak College of Arts and Science, India
Highest Degree
Ph.D. in Medical Biochemistry from University of Madras, Chennai, India
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Mohamed Sathak College of Arts and Science, India
Biography
Dr. Ayyakkannu Purushothaman is currently working as Assistant Professor & Head of PG & Research Department of Biochemistry at Mohamed Sathak College of Arts and Science, Chennai, India. He completed his Ph.D. in Medical Biochemistry (Cancer Biology). His main area of interest is in Pharmacology and Toxicology, Biomedical Sciences and Molecular Sciences. He has published more than 20 peer reviewed national/international journals. He has also invited as reviewer for the Journal Medicinal Chemistry Research of SPRINGER and reviewed couple of research papers. His Ph.D. Research article published in Asian Pacific Journal of tropical Medicine (ELSEVIER) Ranked 7th on the TOP 25 Hottest most downloaded articles. He is also the member of Indian Science Congress Association (ISCA).
Area of Interest:
Pharmacology and Toxicology
100%
Antioxidants
62%
Herbal Extract
90%
Apoptosis
75%
HPLC
55%
Research Publications in Numbers
Books
0
0
Chapters
0
0
Articles
17
17
Abstracts
0
0
Selected Publications
- Purushothaman, A., E. Nandhakumar, P. Shanthi and P. Sachdanandam, 2015. Antiproliferative and apoptotic effects of Shemamruthaa, a herbal preparation, in 7,12-dimethylbenz(a)anthracene-induced breast cancer rats. J. Evidence-Based Complement. Altern. Medic. 10.1177/2156587215580434.
CrossRef | Direct Link | - Nandhakumar, E., A. Purushothaman, S. Palanivelu and P. Sachdanandam, 2015. In vitro antioxidant potential of Shemamruthaa (a herbal formulation) and its anticancer activity in the MCF-7 cell line. RSC Adv., 5: 23125-23133.
CrossRef | Direct Link | - Purushothaman, A., E. Nandhakumar, P. Shanthi and P. Sachdanandam, 2014. Shemamruthaa, a herbal formulation modulates xenobiotic and carbohydrate metabolizing enzymes in 7,12-dimethylbenz[a]anthracene induced breast cancer in rats. J. Biochem. Technol., 5: 801-807.
Direct Link | - Nandhakumar, E., A. Purushothaman, S. Palanivelu and P. Sachdanandam, 2014. Free radical quenching effect of Shemamruthaa- a Siddha drug in 7,12-dimethylbenz(a)anthracene-induced experimental breast cancer rats. Compa. Clin. Pathol., 23: 1703-1713.
CrossRef | Direct Link | - Nandhakumar, E., A. Purushothaman and P. Sachdanandam, 2014. Protective effect of Shemamruthaa on lipids anomalies in 7, 12-dimethylbenz(a)anthracene induced mammary carcinoma bearing rats. Medic. Chem. Res., 23: 3491-3502.
CrossRef | Direct Link | - Nandhakumar, E., A. Purushothaman and P. Sachdanandam, 2014. Acute and subacute toxicity studies with Shemamruthaa, a modified indigenous siddha preparation in sprague-dawley rats. Food Sci. Biotechnol., 23: 299-306.
CrossRef | Direct Link | - Purushothaman, A., E. Nandhakumar and P. Sachdanandam, 2013. Phytochemical analysis and anticancer capacity of Shemamruthaa, an herbal formulation against DMBA- induced mammary carcinoma in rats. Asian Pacific J. Trop. Medic., 6: 925-933.
CrossRef | Direct Link | - Shahjahan, M., A. Purushothaman, M. Nadarajan, K.P. Meenatchi, S. Saravanan and A. Thangaraj, 2012. Synergistic effects of Solanum trilobatum and Solanum melongena extract against β-galactosamine induced hepatic damage in rats. Am. J. Bio-Pharmacol. Biochem. Life Sci., 1(Suppl 1): A32-A32.
- Saratha, K., M. Packirisamy, M.N. Kathiravan and A. Purushothaman, 2012. Isolation and characterisation of Cr(VI) reducing Bacillus sp. from tannery effluents contaminated soil and its potential use in bioremediation of chromium containing wastewater. J. Modern Sci. (J. Tamil Nadu State Council Higher Educ.), 4: 24-35.
- Purushothaman, A., T. Ahmad, P. Meenatchi, M.N. Kathiravan and M. Shahjahan, 2012. Combined effects of Solanum trilobatum and Solanum melongena against β-galactosamine induced hepatic damage in rats with reference to marker enzymes and antioxidants status. BioChemistry: Indian J., 6: 49-56.
Direct Link | - Purushothaman, A., E. Nandhakumar and P. Sachdanandam, 2012. Modulation of lipid peroxidation and antioxidant status upon administration of Shemamruthaa in 7,12-dimethylbenz[a]anthracene induced mammary carcinoma bearing rats. Asian Pacific J. Trop. Biomedic., 2: S765-S771.
CrossRef | Direct Link | - Purushothaman, A., E. Nandhakumar and P. Sachdanandam, 2012. Anticancer effect of Shemamruthaa (a phytochemical formulation) on 7, 12-dimethylbenz(a)anthracene induced mammary carcinoma in rats. Asian J. Pharm. Clin. Res., 5: 101-107.
Direct Link | - Deepalakshmi, J., K. Ambika, A. Purushothaman and M.N. Kathiravan, 2012. Investigation of the antioxidant and antimicrobial activity of methanolic extracts of raw and cooked scallion (Allium wakegi). Am. J. Bio-Pharmacol. Biochem. Life Sci., 1(Suppl 1): A62-A62.
- Sarjoon, M.J.M.H., P. Meenatchi, M.N. Kathiravan, M. Shahjahan and A. Purushothaman, 2011. Optimization of operating parameters and kinetic studies on removal of hexavalent chromium from aqueous solutions using Citrus limetta peel biomass. Int. J. Environ. Biol., 1: 8-14.
Direct Link | - Purushothaman, A., P. Meenatchi, M.N. Kathiravan, M. Shahjahan and J. Deepalakshmi, 2011. Investigation of cadmium and lead induced phytotoxicity on seed germination, seedling growth and antioxidant metabolism of chick pea (Cicer arietinum L.). Int. J. Curr. Res., 33: 18-23.
Direct Link | - Purushothaman, A., P. Meenatchi, G. Suganya and J. Deepalakshmi, 2011. Amelioration of cytotoxic effects of methylparaben by Hibiscus rosasinensis L. flowers: An in vitro study on erythrocytes. J. Pharmacy Res., 4: 2047-2050.
- Meenatchi, P., A. Purushothaman, J. Deepalakshmi, M.N. Kathiravan and M. Shahjahan, 2011. Protective effect of Hibiscus polyphenol-rich extract against H2O2 induced oxidative damage of human erythrocytes. J. Cell Tissue Res., 11: 2545-2550.