Dr. Haroon Khan
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Dr. Haroon Khan

Professor
Department of Pharmacy, Abdul Wali Khan University Mardan, Pakistan

Highest Degree
Ph.D. in Pharmaceutical Sciences from University of Peshawar, Pakistan

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Area of Interest:

Biomedical Sciences
100%
Phytochemical Property
62%
Pharmaceutical Sciences
90%
Bioassays
75%
Therapeutics
55%

Research Publications in Numbers

Books
9
Chapters
13
Articles
405
Abstracts
0

Selected Publications

  1. Sharifi, S., H. Khan, E.D. Abdolahinia, S. Ahmadian and S. Bohlouli et al., 2023. Effect of curcumin on the head and neck squamous cell carcinoma cell line HN5. Curr. Mol. Pharmacol., 16: 374-380.
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  2. Saleem, U., S. Iman, B. Ahmad, M.A. Shah and S. Bibi et al., 2023. Antidepressant activity of phytochemicals of Mangifera indica seeds assisted by integrated computational analysis. Metab. Brain Dis., 38: 483-505.
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  3. Khan, H., S. Sabreen, S. Niaz, A. Hussain and I. Muhammad et al., 2023. Antifungal potential of selected medicinal plants against Candida albicans and HPLC analysis. Curr. Bioact. Compd., Vol. 19. 10.2174/1573407218666220620114814.
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  4. Bishayee, A., S. Mirzaei, M.H. Gholami, A. Zabolian and H. Saleki et al., 2023. Resveratrol augments doxorubicin and cisplatin chemotherapy: A novel therapeutic strategy. Curr. Mol. Pharmacol., 16: 280-306.
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  5. Tobeiha, M., A. Jafari, S. Fadaei, S.M.A. Mirazimi and F. Dashti et al., 2022. Evidence for the benefits of melatonin in cardiovascular disease. Front. Cardiovasc. Med., Vol. 9. 10.3389/fcvm.2022.888319.
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  6. Shahcheraghi, S.H., F. Salemi, W. Alam, H. Ashworth, L. Saso, H. Khanc and M. Lotfi, 2022. The role of NRF2/KEAP1 pathway in glioblastoma: Pharmacological implications. Med Oncol., Vol. 39. 10.1007/s12032-022-01693-0.
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  7. Shah, M.J., A. Hamid, H.I. Faheem, A. Rasul and T.A.S. Baokbah et al., 2022. Uncovering the anticancer potential of polydatin: A mechanistic insight. Molecules, Vol. 27. 10.3390/molecules27217175.
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  8. Salemi, F., W. Alam, M.S. Hassani, S.Z. Hashemi and A.A. Jafari, 2022. Neuroblastoma: Essential genetic pathways and current therapeutic options. Eur. J. Pharmacol., Vol. 926. 10.1016/j.ejphar.2022.175030.
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  9. Sadrkhanloo, M., M. Entezari, S. Orouei, A. Zabolian and A. Mirzaie et al., 2022. Targeting Nrf2 in ischemia-reperfusion alleviation: From signaling networks to therapeutic targeting. Life Sci., Vol. 300. 10.1016/j.lfs.2022.120561.
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  10. Rauf, A., M. Akram, H. Anwar, M. Daniyal and N. Munir et al., 2022. Therapeutic potential of herbal medicine for the management of hyperlipidemia: Latest updates. Environ. Sci. Pollut. Res., 29: 40281-40301.
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  11. Rahman, N., S. Begum, A. Khan, S.G. Afridi and M.U.K. Sahibzada et al., 2022. An insight in Salmonella typhi associated autoimmunity candidates prediction by molecular mimicry. Comput. Biol. Med., Vol. 148. 10.1016/j.compbiomed.2022.105865.
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  12. Mahabady, M.K., S. Mirzaei, H. Saebfar, M.H. Gholami and A. Zabolian et al., 2022. Noncoding RNAs and their therapeutics in paclitaxel chemotherapy: Mechanisms of initiation, progression, and drug sensitivity. J. Cell. Physiol., 237: 2309-2344.
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  13. Hussain, Y., H. Khan, W. Alam, M. Aschner, Abdullah, K.F. Alsharif and L. Saso, 2022. Flavonoids targeting the mTOR signaling cascades in cancer: A potential crosstalk in anti-breast cancer therapy. Oxid. Med. Cell. Longevity, Vol. 2022. 10.1155/2022/4831833.
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  14. Hussain, Y., H. Khan, K.F. Alsharif, A.H. Khan, M. Aschner and L. Saso, 2022. The therapeutic potential of kaemferol and other naturally occurring polyphenols might be modulated by Nrf2-ARE signaling pathway: Current status and future direction. Molecules, Vol. 27. 10.3390/molecules27134145.
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  15. Hussain, Y., Abdullah, K.F. Alsharif, M. Aschner and A. Theyab et al., 2022. Therapeutic role of carotenoids in blood cancer: Mechanistic insights and therapeutic potential. Nutrients, Vol. 14. Vol. 2022. 10.3390/nu14091949.
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  16. Ashrafizadeh, M., H. Saebfar, M.H. Gholami, K. Hushmandi and A. Zabolian et al., 2022. Doxorubicin-loaded graphene oxide nanocomposites in cancer medicine: Stimuli-responsive carriers, co-delivery and suppressing resistance. Expert Opin. Drug Delivery, 19: 355-382.
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  17. Ali, A., T.L. Sampaio, H. Khan, P. Jeandet, E.K. Akkol, H. Bahadar and A.M.C. Martins, 2022. Plants with therapeutic potential for ischemic acute kidney injury: A systematic review. Evidence-Based Complementary Altern. Med., Vol. 2022. 10.1155/2022/6807700.
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  18. Akkol, E.K., H. Bardakci, T.H. Barak, M. Aschner, G.Ş. Karatoprak, H. Khan and Y. Hussain, 2022. Herbal ingredients in the prevention of breast cancer: Comprehensive review of potential molecular targets and role of natural products. Oxid. Med. Cell. Longevity, Vol. 2022. 10.1155/2022/6044640.
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  19. Ahmed, S., H. Khan, S. Fakhri, M. Aschner and W.S. Cheang, 2022. Therapeutic potential of marine peptides in cervical and ovarian cancers. Mol. Cell. Biochem., 477: 605-619.
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  20. Ahmad, S.S., K. Younis, J. Philippe, M. Aschner and H. Khan, 2022. Strategic approaches to target the enzymes using natural compoundsfor the management of Alzheimer's disease: A review. CNS Neurol. Disord. Drug Targets, 21: 610-620.
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  21. Rehman, S. and H. Khan, 2017. Advances in antioxidant potential of natural alkaloids. Curr. Bioact. Compd. 13: 101-108.
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  22. Rauf, A., T.B. Hadda, G. Uddin, J.P. Cerón-Carrasco and J. Peña-García et al., 2017. Sedative-hypnotic-like effect and molecular docking of di-naphthodiospyrol from Diospyros lotus in an animal model. Biomed. Pharmacother., 88: 109-113.
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  23. Rauf, A., S. Uysal, T.B. Hadda, G. Uddin and M.A. Nawaz et al., 2017. In vivo and in silico sedative-hypnotic like activity of 7-methyljuglone isolated from Diospyros lotus L. Biomed. Pharmacother., 87: 678-682.
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  24. Rauf, A., S. Uysal, T.B. Hadda, B.S. Siddiqui and H. Khan et al., 2017. Antibacterial, cytotoxicity, and phytotoxicity profiles of three medicinal plants collected from Pakistan. Marmara Pharm. J., 21: 261-261.
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  25. Rauf, A., I.E. Orhan, A. Ertas, H. Temel and T.B. Hadda et al., 2017. Elucidation of phosphodiesterase-1 inhibitory effect of some selected natural polyphenolics using in vitro and in silico methods. Curr. Top. Med. Chem., 17: 412-417.
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  26. Patel, S., A. Rauf, H. Khan, S. Khalid and M.S. Mubarak, 2017. Potential health benefits of natural products derived from truffles: A review. Trends Food Sci. Technol., 70: 1-8.
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  27. Patel, S., A. Rauf, H. Khan, B.R. Meher and S.S. ul Hassan, 2017. A holistic review on the autoimmune disease vitiligo with emphasis on the causal factors. Biomed. Pharmacother., 92: 501-508.
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  28. Patel, S., A. Rauf, H. Khan and T. Abu-Izneid, 2017. Renin-angiotensin-aldosterone (RAAS): The ubiquitous system for homeostasis and pathologies. Biomed. Pharmacother., 94: 317-325.
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  29. Naz, S., U. Farooq, A. Khan, H. Khan and N. Karim et al., 2017. Antidepressent Effect of Two New Benzyl Derivatives from Wild Strawberry Fragaria vesca var. nubicola Lindl. ex Hook.f. Front. Pharmacol., Vol. 8. 10.3389/fphar.2017.00469.
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  30. Khan, H., Z. Khan, S. Amin, Y.N. Mabkhot, M.S. Mubarak, T.B. Hadda and F. Maione, 2017. Plant bioactive molecules bearing glycosides as lead compounds for the treatment of fungal infection: A review. Biomed. Pharmacother., 93: 498-509.
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  31. Khan, H., S. Patel and M.A. Kamal, 2017. Pharmacological and toxicological profile of harmane-β-carboline alkaloid: Friend or foe. Curr. Drug Metab., 18: 853-857.
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  32. Jawad, M., H. Khan, S. Pervez, S.S. Bawazeer, T. Abu-Izneid, M. Saeed and M.A. Kamal, 2017. Pharmacological validation of the anxiolytic, muscle relaxant and sedative like activities of Capsicum annuum in animal model. Bangladesh J. Pharmacol., 12: 439-437.
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  33. Gupta, M., V. Sharma and S.P. Vyas, 2017. Editorial: Structured nanosystems for dermal delivery of therapeutics: Options, opportunities and clinical implications. Curr. Drug Metabo., 18: 402-403.
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  34. Ghaffar, R., M. Saeed, M. Ahmad, H. Khan and S. Ahmad, 2017. In vivo anti-inflammatory characterization of crude extract and solvent fractions of Viola serpens. Pure Appl. Biol., 6: 18-31.
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  35. Ali, M., A. Rauf, T. Hadda, S. Bawazeer and T. Abu-Izneid et al., 2017. Mechanisms underlying anti-hyperalgesic properties of kaempferol-3,7- di-O-α-L-rhamnopyranoside isolated from dryopteris cycadina. Curr. Top. Med. Chem., 17: 383-390.
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  36. Zafar, M., H. Khan, A. Rauf, A. Khan amd M.A. Lodhi, 2016. In silico study of alkaloids as α-glucosidase inhibitors: Hope for the discovery of effective lead compounds. Front. Endocrinol., Vol. 7. 10.3389/fendo.2016.00153.
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  37. Uddin, G., Ismail, A. Rauf, M. Raza and H. Khan et al., 2016. Urease inhibitory profile of extracts and chemical constituents of Pistacia atlantica ssp. cabulica stocks. Nat. Prod. Res., 30: 1411-1416.
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  38. Rauf, A., J. Ali, H. Khan, M.S. Mubarak and S. Patel, 2016. Emerging CAM Ziziphus nummularia with in vivo sedative-hypnotic, antipyretic and analgesic attributes. 3 Biotech, Vol. 6. 10.1007/s13205-015-0322-5.
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  39. Rauf, A., G. Uddin, H. Khan, M. Raza, M. Zafar and H. Tokuda, 2016. Anti-tumour-promoting and thermal-induced protein denaturation inhibitory activities of β-sitosterol and lupeol isolated from Diospyros lotus L. Nat. Prod. Res., 30: 1205-1207.
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  40. Rauf, A., F. Maione, G. Uddin, M. Raza and B.S. Siddiqui et al., 2016. Biological evaluation and docking analysis of daturaolone as potential cyclooxygenase inhibitor. Evidence-Based Complementary Altern. Med., Vol. 2016. 10.1155/2016/4098686.
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  41. Perviz, S., H. Khan and A. Pervaiz, 2016. Plant alkaloids as an emerging therapeutic alternative for the treatment of depression. Front. Pharmacol., Vol. 7. 10.3389/fphar.2016.00028.
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  42. Khan, H., M.A. Khan, S. Hussain, R. Gaffar and N. Ashraf, 2016. In vivo antinociceptive and anticonvulsant activity of extracts of Heliotropium strigosum. Toxicol. Ind. Health, 32: 860-865.
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  43. Khan, H., M. Saeed, N. Muhammad and S. Perviz, 2016. Phytochemical analysis, antibacterial, and antifungal assessment of aerial parts of Polygonatumverticillatum. Toxicol. Ind. Health, 32: 841-847.
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  44. Raziq, N., M. Saeed, M. Shahid, N. Muhammad, H. Khan and F. Gul, 2015. Pharmacological basis for the use of Hypericum oblongifolium as a medicinal plant in the management of pain, inflammation and pyrexia. BMC Complement Altern. Med., Vol. 16. 10.1186/s12906-016-1018-z.
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  45. Khan, H., M. Saeed, N. Muhammad, A. Rauf, A.Z. Khan and R. Ullah, 2015. Antioxidant profile of constituents isolated from Polygonatumverticillatum rhizomes. Toxicol. Ind. Health, 32: 138-142.
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