Dr. Allah Nawaz
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Dr. Allah Nawaz

Assistant Professor
University of Toyama, Japan

Highest Degree
Ph.D. in Internal Medicine from Toyama University, Japan

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Area of Interest:

Pharmacology and Toxicology
100%
Obesity
62%
Metabolic Disorder
90%
Insulin Resistance
75%
Advanced Pharmacology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
51
Abstracts
9

Selected Publications

  1. Jeelani, I., M. Bhosale, A. Nawaz, H. Abe and S. Padhye, 2022. Site-specific binding of anti-cancer drugs to human serum albumin. Anti-Cancer Agents Med. Chem., 22: 2876-2884.
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  2. Alam, M.W., S.I. Bhat, H.S. Al Qahtani, M. Aamir and M.N. Amin, et al., 2022. Recent progress, challenges, and trends in polymer-based sensors: A review. Polymers, 10.3390/polym14112164.
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  3. Watanabe, Y., S. Fujisaka, K. Ikeda, M. Ishikawa and T. Yamada et al., 2021. Gut microbiota, determined by dietary nutrients, drive modification of the plasma lipid profile and insulin resistance. iScience, 10.1016/j.isci.2021.102445.
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  4. Ono, Y., O. Yoshino, T. Hiraoka, E. Sato and A. Furue et al., 2021. CD206+?macrophage is an accelerator of endometriotic-like lesion via promoting angiogenesis in the endometriosis mouse model. Sci. Rep., Vol. 11. 10.1038/s41598-020-79578-3.
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  5. Nishida, Y., A. Nawaz, K. Hecht and K. Tobe, 2021. Astaxanthin as a novel mitochondrial regulator: A new aspect of carotenoids, beyond antioxidants. Nutrients. 10.3390/nu14010107.
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  6. Nawaz, A., Y. Nishida, A. Takikawa, S. Fujisaka and T. Kado, et al., 2021. Astaxanthin, a marine carotenoid, maintains the tolerance and integrity of adipose tissue and contributes to its healthy functions. Nutrients, 10.3390/nu13124374.
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  7. Kuwano, T., H. Izumi, M.R. Aslam, Y. Igarashi and M. Bilal et al., 2021. Generation and characterization of a meflin-creert2 transgenic line for lineage tracing in white adipose tissue. PLoS ONE, Vol. 16, 10.1371/journal.pone.0248267.
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  8. Bilal, M., A. Nawaz, T. Kado, M.R. Aslam and Y. Igarashi et al., 2021. Fate of adipocyte progenitors during adipogenesis in mice fed a high-fat diet. Mol. Metab., Vol. 54. 10.1016/j.molmet.2021.101328.
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  9. Nishida, Y., A. Nawaz, T. Kado, A. Takikawa, Y. Igarashi, Y. Onogi, T. Wada, T. Sasaoka, S. Yamamoto, M. Sasahara, J. Imura, K. Tokuyama, I. Usui, T. Nakagawa, S. Fujisaka, Y. Kunimasa and K. Tobe, 2020. Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway. J. Cachexia Sarcopenia Muscle, 11: 241-258.
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  10. Fujisaka, S., I. Usui, A. Nawaz, Y. Igarashi, K. Okabe, Y. Furusawa, S. Watanabe, S. Yamamoto, M. Sasahara, Y. Watanabe, Y. Nagai, K. Yagi, T. Nakagawa and K. Tobe, 2020. Bofutsushosan improves gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in mice with diet-induced obesity. Sci. Rep., 10.1038/s41598-020-62506-w.
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  11. Takikawa, A., I. Usui, S. Fujisaka, K. Tsuneyama, K. Okabe, T. Nakagawa, A. Nawaz, T. Kado, T. Jojima, Y. Aso, Y. Hayakawa, K. Yagi and K. Tobe, 2019. Macrophage‐specific hypoxia‐inducible factor‐1α deletion suppresses the development of liver tumors in high‐fat diet‐fed obese and diabetic mice. J. Diabetes Investig., 10: 1411-1418.
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  12. Okabe, K., A. Nawaz, S. Fujisaka, K. Yagi, T. Kado, I. Sui, T. Nakagawa and K. Tobe, 2019. 1987-P: Nampt deletion changes metabolism in adipose tissue and prevents diet-induced obesity. Diabetes, 10.2337/db19-1987-p.
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  13. Nawaz, A., T. Nakagawa, K. Yagi, S. Fujisaka, K. Tobe, K. Okabe, T. Kado, J. Liu and M. Bilal, 2019. 188-OR: Partial depletion of CD206 M2-like macrophages enhances preadipocyte differentiation via reduction of Wnt signaling. Diabetes, 10.2337/db19-188-or.
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  14. Nawaz, A. and K. Tobe, 2019. M2‐like macrophages serve as a niche for adipocyte progenitors in adipose tissue. J. Diabetes Investig., 10: 1394-1400.
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  15. Kado, T., A. Nawaz, A. Takikawa, I. Usui and K. Tobe, 2019. Linkage of CD8+ T cell exhaustion with high-fat diet-induced tumourigenesis. Sci. Rep., 10.1038/s41598-019-48678-0.
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  16. Ono, Y., M. Nagai, O. Yoshino, K. Koga and A. Nawaz et al., 2018. CD11c+ M1-like macrophages(MΦs) but not CD206+ M2-like MΦare involved in folliculogenesis inmice ovary. Sci. Rep., 10.1038/s41598-018-25837-3.
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  17. Nawaz, A., S. Fujisaka, I. Usui, K. Yagi, T. Nakagawa, T. Kado, K. Tobe, Y. Igarashi, K. Okabe, anda K. Seki 2018. Depletion of CD2M2-Like macrophages promotes the browning of the white adipose tissue. Diabetes, 10.2337/db18-1749-P.
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  18. Nawaz, A., A. Mehmood, Y. Kanatani, T. Kado, Y. Igarashi, A. Takikawa, S. Yamamoto, K. Okabe, T. Nakagawa, K. Yagi, S. Fujisaka and K. Tobe, 2018. Sirt1 activator induces proangiogenic genes in preadipocytes to rescue insulin resistance in diet-induced obese mice. Sci. Rep., 10.1038/s41598-018-29773-0.
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  19. Igarashi, Y., A. Nawaz, T. Kado, M. Bilal, T. Kuwano, S. Yamamoto, M. Sasahara, Xu. Jiuxiang, A. Inujima, K. Koizumi, J. Imura, N. Shibahara, I. Usui, S. Fujisaka and K. Tobe, 2018. Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation. Sci. Rep., 10.1038/s41598-018-32803-6.
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  20. Fujisaka, S., I. Usui, A. Nawaz, Y. Igarashi, T. Kado, K. Okabe, K. Yagi, T. Nakagawa and K. Tobe 2018. Bofutsushosan improves gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in diet-induced obese mice. Diabetes, 10.2337/db18-1990-P.
    CrossRef  |  Direct Link  |  
  21. Okabe, K., I. Usui, A. Nawaz, S. Fujisaka, T. Kado, Y. Igarashi, K. Yagi, K. Tobe and T. Nakagawa 2018. NAD-Mediated metabolic reprogramming epigenetically regulates gene expression to promote preadipocyte differentiation. Diabetes, 10.2337/db18-360-OR.
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  22. Nawaz, A., T. Kado, Y. Igarashi, Y. Kunimasa, I. Usui, S. Fujisaka and K. Tobe, 2017. Adipose tissue-resident macrophages and obesity. RADS J. Pharm. Pharm. Sci., 5: 57-62.
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  23. Nawaz, A., A. Aminuddin, T. Kado, A. Takikawa and S. Yamamoto et al., 2017. CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors. Nat. Commun., Vol. 8, No. 1. 10.1038/s41467-017-00231-1.
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  24. Akram, M. and A. Nawaz, 2017. Effects of medicinal plants on Alzheimer’s disease and memory deficits. Neural Regen. Res., 12: 660-670.
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  25. Akram, M. and A. Nawaz, 2017. Effects of medicinal plants on Alzheimer's disease and memory deficits. Neural Regen. Res., 12: 660-670.
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  26. Takikawa, A., A. Mahmood, A. Nawaz, T. Kado and K. Okabe et al., 2016. HIF-1α in myeloid cells promotes adipose tissue remodeling toward insulin resistance. Diabetes, 10.2337/db16-0012.
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  27. Sultana, T., S. Naveed, A. Nawaz, J.S. Muhammad and S.F. Zaidi et al., 2016. The use of cissus quadrangularis in the management of left tibia fracture: A case report. Rad. J. Pharm. Pharm. Sci., 4: 117-122.
  28. Siddiqui, M.S.A., A. Saeed, A. Nawaz, S. Naveed and K. Usmanghani, 2016. The effects of new polyherbal Unani formulation AJMAL06 on serum creatinine level in chronic renal failure. Pak. J. Pharm. Sci., 29: 657-661.
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  29. Nawaz, A., H. Nazar, K. Usmanghani, Z.A. Sheikh, M.A. Chishti and I. Ahmad, 2016. Ways to manage hepatitis C without cirrhosis: Treatment by comparison of coded eastern medicine hepcinal with interferon alpha 2b and ribavirin. Pak. J. Pharm. Sci., 29: 919-927.
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  30. Toseef, M.U., A. Saeed, E. Mohi-ud-Din, K. Usmanghani and H. Nazar et al., 2015. Comparative clinical evaluation on herbal formulation pepsil, safoof-e-katira and omeprazole in gastro esophageal reflux disease. Pak. J. Pharm. Sci., 28: 863-870.
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  31. Sheikh, Z.A., K. Usmanghani, H. Nazar, A. Nawaz, L.R. Jahanzeb and I. Ahmad, 2015. Comparative clinical study on the efficacy of biocor plus compared with simvastatin for the management of hypercholesterolemia. Pak. J. Pharm. Sci., 28: 2291-2295.
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  32. Shakeel, S., K. Usmanghani, A. Nawaz, S.A. Zakki, Z.G. Cui, S. Abrahim and T.A. Mir, 2015. Evaluation of in vitro lipoxygenase inhibition and antioxidant activity of polyherbal formulation entoban. Rads J. Pharm. Pharm. Sci., 3: 82-88.
  33. Senda, S., A. Inoue, A. Mahmood, R. Suzuki and N. Kamei et al., 2015. Calorie restriction-mediated restoration of hypothalamic signal transducer and activator of transcription 3 (STAT3) phosphorylation is not effective for lowering the body weight set point in IRS-2 knockout obese mice. Diabetology Int., 6: 321-335.
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  34. Nawaz, A., Z.A. Sheikh, M. Feroz, K. Alam, H. Nazar and K. Usmanghani, 2015. Clinical efficacy of polyherbal formulation eezpain spray for muscular pain relief. Pak. J. Pharm. Sci., 28: 43-47.
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  35. Nawaz, A., S.F. Zaidi, K. Usmanghani and I. Ahmad, 2015. Concise review on the insight of hepatitis C. J. Taibah Univ. Med. Sci., 10: 132-139.
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  36. Mir, T.A., S. Abrahim, A. Nawaz, S.I. Wani and Mati-ur-Rehman, 2015. Biosensors and their biomedical applications: Invited review. Rads J. Pharm. Pharm. Sci., 3: 104-112.
  37. Daniyal, M., M. Akram, Abdul Hamid, A. Nawaz, I. Azhar, K. Usmanghani and S. Ahmed, 2015. Comprehensive review on treatment of HIV. Pak. J. Pharm. Sci., .
  38. Chishti, M.A., H. Nazar, K. Usmanghani, Rukh-e-Nasreen and A. Nawaz, 2015. Clinically evaluation of an herbal medicine acidom in hyperacidity. Rads J. Pharm. Pharm. Sci., 3: 72-77.
  39. Ayaz, S., K. Usmanghani, A. Nawaz, S. Khan and E. Mohiuddin, 2015. Evaluation of the clinical efficacy of comparison of irocibin iron polymaltose (herbal complex) and iberet for the treatment of iron deficiency anemia. Rads J. Pharm. Pharm. Sci., 3: 50-57.
  40. Akram, M., A. Nawaz, Abdul Hamid, K. Ahmed and Abdul Ghaffar et al., 2015. Plants with anti-hypertensive activity: A review. Trop. J. Pharm. Res., .
  41. Sheikh, Z.A., A.A. Khan, A. Nawaz, A. Zahoor, Z.A. Siddiqui, S.S. Khan and K. Usmanghani, 2014. Development and clinical evaluation of polyherbal laxative laxisen. J. Pharm. Pharm. Sci., 2: 63-70.
  42. Sheikh, Z.A., A. Zahoor, A. Nawaz, S.S. Khan, Z.A. Siddiqui, A.A. Khan and K. Usmanghani, 2014. Concise review: Efficacy and safety of verona in patients with oligospermia_meta analytical insight and management. J. Pharm. Pharm. Sci., 2: 35-40.
  43. Nawaz, A., Z.A. Sheikh and K. Alam, 2014. Clinical efficacy of polyherbal formulation dermidoc cream for dermatitis. Best Int. J. Humanities Arts Med. Sci., 2: 75-80.
  44. Nawaz, A., S. Bano, Z.A. Sheikh, K. Usmanghani, I. Ahmad, S.F. Zaidi, A. Zahoor and I. Ahmad 2014. Evaluation of acute and repeated dose toxicity of the polyherbal formulation linkus syrup in experimental animals. Chin. Med., 05: 179-189.
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  45. Nawaz, A., S. Bano, Z.A. Sheikh, K. Usmanghani and I. Ahmad et al., 2014. Evaluation of acute and repeated dose toxicity of the polyherbal formulation linkus syrup in experimental animals. Chin. Med., 5: 179-189.
  46. Nawaz, A., A. Iqbal, A. Ahmed, A. Mushtaq, M.A. Chishti, I. Ahmad and K. Usmanghani, 2014. Treatment of sciatica by Hijama (regimental therapy-cupping). J. Pharm. Pharm. Sci., 2: 22-25.
  47. Nawaz, A., U. Khan, M.U. Toseef, A. Saeed and I. Ahmad, 2013. Introduction of gastrointestinal reflux disease and unani concepts. Rads J. Biol. Res. Appl. Sci., 4: 36-46.
  48. Nawaz, A., K. Alam, Z.A. Sheikh, N. Khatoon and S.M. Amir et al., 2013. Design, development, and evaluation of antimicrobial activity of herbal antiseptic wound pad-neemplast. Afr. J. Pharm. Pharmacol., 7: 2341-2347.
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  49. Akram, M., A. Nawaz, H.M. Asif, K. Usmanghani and A. Hamid, 2013. Anti-nociceptive activities of medicinal plants: A review. Rads J. Biol. Res. Appl. Sci., 4: 50-58.