Biography

Dr. Afaf H. Alnadaf holds a position of Associate Professor at Mutah University, Jordan. She obtained her Ph.D. in Organic Chemistry from same University. Her main area of interest related to Computer-Aided Molecular Design Techniques, Organic/Green Chemistry and Drug Analysis. Her area of expertise includes Computer-Aided Molecular Design, 3D-QSAR, Drug Analysis, Polymer Chemistry, Anti-Alzheimers Leads, Multi-Targets, Synthetic Modifications, Traditional QSAR Models, and Green Approaches in Synthetic Chemistry, Microwave Synthesis, Anti-Hypertensive Leads, and Cyclodextrin Complexes. She is author/co-author of 6 journal papers.

Area of Interest:

Chemistry

100%

Organic Chemistry

62%

Green Chemistry

90%

Drug Analysis

75%

Synthetic Modifications

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
24

Abstracts
0

Selected Publications

Al-Nadaf, A.H., S.A. Salah and M.O. Taha, 2018. Discovery of new Gyrase β inhibitors via structure based modeling. Comput. Biol. Chem., 74: 263-272.
Al-Nadaf, A.H., N.J. Seder and W. Abu Rayyan, 2018. Wound healing; antimicrobial and anti-oxidant activity for Jordanian Juglans regia L. unripe fruits. J. Innovations Pharm. Biol. Sci., 5: 26-34.
Direct Link |
Al-Nadaf, A.H., H.M. Bastoni and D.F. Hamdan, 2018. Microwave-assisted efficient extraction of phenolics from Juglans regia L.: Pellicle; kernel unripe fruits and leaves in different solvents. Int. J. Green Pharm., 12: 182-190.
Direct Link |
Thiab, S.H., I.I. Hamdan, D. El-Sabawi and A.H. Al-Nadaf, 2016. Effect of loratadine on the dissolution and bioavailability of gliclazide from its hydroxypropyl-β-cyclodextrin complex. J. Inclusion Phenomena Macrocyclic Chem., 85: 203-216.
CrossRef | Direct Link |
Al-Nadaf, A.H., M.O. Taha and H.K. Aldal'in, 2015. Haloperidol inhibits Memapsin 2: Innovation by docking simulation and in vitro assay. Pak. J. Pharm. Sci3, 28: 139-146.
Al-Nadaf, A.H. and M.O. Taha, 2015. Identification of small molecule memapsin inhibitors via computation-based virtual screening. Adv. Pharmacol. Pharm., 3: 53-63.
Taha, M.O., M.A. Al-Sha'er, M.A. Khanfar and A.H. Al-Nadaf, 2014. Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis. Eur. J. Med. Chem., 84: 454-465.
CrossRef | Direct Link |
Al-Shawabkeh, J.D., A.H. Al-Nadaf, L.A. Dahabiyeh and M.O. Taha, 2014. Design, synthesis and structure-activity relationship of new HSL inhibitors guided by pharmacophore models. Med. Chem. Res., 23: 127-145.
CrossRef | Direct Link |
Al-Nadaf, A. and M.O. Taha, 2013. Ligand-based pharmacophore exploration and QSAR analysis of transition state analogues followed by in silico screening guide the discovery of new sub-micromolar β-secreatase inhibitors. Med. Chem. Res., 22: 1979-1997.
CrossRef | Direct Link |
Aldal'in, H.K.H., A.H. Al-Nadaf and A.W.R. Hamad, 2012. Study the effect of photoperiod duration on dynamic carbohydrates composition and enzymes activity in soybean leaves. Pak. J. Nutr., 11: 1166-1176.
CrossRef | Direct Link |
Al-Nadaf, A.H. and M.O. Taha, 2011. Discovery of new renin inhibitory leads via sequential pharmacophore modeling, QSAR analysis, in silico screening and in vitro evaluation. J. Mol. Graphics Modell., 29: 843-864.
CrossRef | PubMed | Direct Link |
Mohammad, M.K., I.M. Almasri, K. Tawaha, A. Issa and A. Al-Nadaf et al., 2010. Antioxidant, antihyperuricemic and xanthine oxidase inhibitory activities of Hyoscyamus reticulatus. Pharm. Biol., 48: 1376-1383.
CrossRef | PubMed | Direct Link |
Al-Nadaf, A., G.A. Sheikha and M.O. Taha, 2010. Elaborate ligand-based pharmacophore exploration and QSAR analysis guide the synthesis of novel pyridinium-based potent β-secretase inhibitory leads. Bioorg. Med. Chem., 18: 3088-3115.
CrossRef | PubMed | Direct Link |