Mr. Zeyad  Nassar
My Social Links

Mr. Zeyad Nassar

Ph.D. Student
University of Queensland, Australia


Highest Degree
Ph.D. Student in Pharmacology from University of Queensland, Australia

Share this Profile

Biography

Mr. Zeyad Nassar is Ph.D. Student in Pharmacology from University of Queensland, Australia. His main area of interest related to Pharmacology and Toxicology, Biomedical Sciences, and Molecular Sciences. His area of expertise includes Cancer, Angiogenesis, and Molecular Targets. He has published 10 research articles in journals.

Area of Interest:

Pharmacology and Toxicology
100%
Cancer Biology
62%
Lymphangiogenesis
90%
Angiogenesis
75%
Apoptosis
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Dighe, S.N., E. De la Mora, S. Chan, S. Kantham and G. McColl et al., 2019. Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model. Commun. Chem., Vol. 2. 10.1038/s42004-019-0133-4.
    Caenorhabditis elegans model.' target='_blank'>CrossRef  |  Caenorhabditis elegans model.' target='_blank'>Direct Link  |  
  2. Balaban, S., Z.D. Nassar, A.Y. Zhang, E. Hosseini-Beheshti and M.M. Centenera et al., 2019. Extracellular fatty acids are the major contributor to lipid synthesis in prostate cancer. Mol. Cancer Res., 17: 949-962.
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Xie, N., N. Matigian, T. Vithanage, K. Gregory and Z.D. Nassar et al., 2018. Effect of perioperative opioids on cancer-relevant circulating parameters: Mu opioid receptor and toll-like receptor 4 activation potential, and proteolytic profile. Clin. Cancer Res., 24: 2319-2327.
    CrossRef  |  PubMed  |  Direct Link  |  
  4. Nassar, Z.D., A.T. Aref, D. Miladinovic, C.Y. Mah, G.V. Raj, A.J. Hoy and L.M. Butler, 2018. Peri-prostatic adipose tissue: The metabolic microenvironment of prostate cancer. BJU Int., 121: 9-21.
    CrossRef  |  PubMed  |  Direct Link  |  
  5. Armstrong, H.K., J.L. Gillis, I.R. Johnson, Z.D. Nassar and M. Moldovan et al., 2018. Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion. Scient. Rep., Vol. 8. 10.1038/s41598-018-19871-4.
    CrossRef  |  Direct Link  |  
  6. Xie, N., S. Khabbazi, Z.D. Nassar, K. Gregory and T. Vithanage et al., 2017. Morphine alters the circulating proteolytic profile in mice: Functional consequences on cellular migration and invasion. FASEB J., 31: 5208-5216.
    CrossRef  |  Direct Link  |  
  7. Xie, N., F.P. Gomes, V. Deora, K. Gregory and T. Vithanage et al., 2017. Activation of μ-opioid receptor and toll-like receptor 4 by plasma from morphine-treated mice. Brain Behav. Immunity, 61: 244-258.
    CrossRef  |  Direct Link  |  
  8. Habib-Martin, Z.A., H.M. Hammad, F.U. Afifi, M. Zihlif and H.J. Al-Ameer et al., 2017. In vitro and in vivo evaluation of the antiangiogenic activities of Trigonella foenum-graecum extracts. Asian Pac. J. Trop. Biomed., 7: 732-738.
    CrossRef  |  Direct Link  |  
  9. Al-Aqtash, R.A., M.A. Zihlif, H. Hammad, Z.D. Nassar, J. Al Meliti and M.O. Taha, 2017. Ligand-based computational modelling of platelet-derived growth factor beta receptor leading to new angiogenesis inhibitory leads. Comput. Biol. Chem., 71: 170-179.
    CrossRef  |  Direct Link  |  
  10. Khabbazi, S., Z.D. Nassar, Y. Goumon and M.O. Parat, 2016. Morphine decreases the pro-angiogenic interaction between breast cancer cells and macrophages in vitro. Scient. Rep., Vol. 6. 10.1038/srep31572.
    CrossRef  |  Direct Link  |  
  11. Armstrong, H.K., Y.C. Koay, S. Irani, R. Das and Z.D. Nassar et al., 2016. A novel class of Hsp90 C-terminal modulators have pre-clinical efficacy in prostate tumor cells without induction of a heat shock response. Prostate, 76: 1546-1559.
    CrossRef  |  Direct Link  |  
  12. Nassar, Z.D., M.M. Hill, R.G. Parton, M. Francois and M.O. Parat, 2015. Non-caveolar caveolin-1 expression in prostate cancer cells promotes lymphangiogenesis. Oncoscience, 2: 635-645.
    CrossRef  |  PubMed  |  Direct Link  |  
  13. Moon, H., J.E. Ruelcke, E. Choi, L.J. Sharpe and Z.D. Nassar et al., 2015. Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1. Oncotarget, 6: 7438-7453.
    CrossRef  |  PubMed  |  Direct Link  |  
  14. Shafaei, A., N.S. Muslim, Z.D. Nassar, A.F.A. Aisha, A.M.S.A. Majid and Z. Ismail, 2014. Antiangiogenic effect of Ficus deltoidea Jack standardised leaf extracts. Trop. J. Pharm. Res., 13: 761-768.
    Direct Link  |  
  15. Jafari, S.F., M.B.K. Ahamed, M.A. Iqbal, F.S.R. Al Suede and S.H. Khalid et al., 2014. Increased aqueous solubility and proapoptotic activity of potassium koetjapate against human colorectal cancer cells. J. Pharm. Pharmacol., 66: 1394-1409.
    CrossRef  |  Direct Link  |  
  16. Hassan, L.E.A., M.B.K. Ahmed, A.S. Abdul Majid, H.M. Baharetha, N.S. Muslim, Z.D. Nassar and A.M.S. Abdul Majid, 2014. Correlation of antiangiogenic, antioxidant and cytotoxic activities of some Sudanese medicinal plants with phenolic and flavonoid contents. BMC Complem. Altern. Med., Vol. 2014. 10.1186/1472-6882-14-406.
    CrossRef  |  Direct Link  |  
  17. Al-Suede, F.S.R., M.A.K. Ahmed, A.S. Abdul Majid, H.M. Baharetha and L.E.A. Hassan et al., 2014. Optimization of cat's whiskers tea (Orthosiphon stamineus) Using supercritical carbon dioxide and selective chemotherapeutic potential against prostate cancer Evid.-Based Complem. Altern. Med., Vol. 2014. 10.1155/2014/396016.
    Orthosiphon stamineus) Using supercritical carbon dioxide and selective chemotherapeutic potential against prostate cancer ' target='_blank'>CrossRef  |  Orthosiphon stamineus) Using supercritical carbon dioxide and selective chemotherapeutic potential against prostate cancer ' target='_blank'>Direct Link  |  
  18. Zihlif, M., F. Afifi, R. Abu-Dahab, A.M. Abdul Majid and H. Somrain et al., 2013. The antiangiogenic activities of ethanolic crude extracts of four salvia species. BMC Complement Altern. Med., Vol. 13. 10.1186/1472-6882-13-358.
    CrossRef  |  PubMed  |  Direct Link  |  
  19. Nassar, Z.D., M.M. Hill, R.G. Parton and M.O. Parat, 2013. Caveola-forming proteins caveolin-1 and PTRF in prostate cancer. Nat. Rev. Urol., 10: 529-536.
    CrossRef  |  Direct Link  |  
  20. Nassar, Z.D., H. Moon, T. Duong, L. Neo and M.M. Hill et al., 2013. PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis. Oncotarget, 4: 1844-1855.
    Direct Link  |  
  21. Baharetha, H.M., Z.D. Nassar, A.F. Aisha, M.B. Ahamed and F.S. Al-Suede et al., 2013. Proapoptotic and antimetastatic properties of supercritical CO2 extract of Nigella sativa Linn. against breast cancer cells. J. Med. Food, 16: 1121-1130.
    CrossRef  |  PubMed  |  Direct Link  |  
  22. Piaru, S.P., R. Mahmud, A.M.S.A. Majid and Z.D.M. Nassar, 2012. Antioxidant and antiangiogenic activities of the essential oils of Myristica fragrans and Morinda citrifolia. Asian Pac. J. Trop. Med., 5: 294-298.
    CrossRef  |  Direct Link  |  
  23. Nassar, Z.D., A.F. Aisha, F.S. Al Suede, A.S. Abdul Majid and A.M. Abdul Majid, 2012. In vitro antimetastatic activity of koetjapic acid against breast cancer cells. Biol. Pharm. Bull., 35: 503-508.
    CrossRef  |  PubMed  |  Direct Link  |  
  24. Muslim, N.S., Z.D. Nassar, A.F. Aisha, A. Shafaei, N. Idris, A.M.S.A. Majid and Z. Ismail, 2012. Antiangiogenesis and antioxidant activity of ethanol extracts of Pithecellobium jiringa. BMC Complement. Altern. Med., Vol. 12. 10.1186/1472-6882-12-210.
    CrossRef  |  Direct Link  |  
  25. Ahamed, M.B.K., A.F. Aisha, Z.D. Nassar, J.M. Siddiqui and Z. Ismail et al., 2012. Cat's whiskers tea (Orthosiphon stamineus) extract inhibits growth of colon tumor in nude mice and angiogenesis in endothelial cells via suppressing VEGFR phosphorylation. Nutr. Cancer, 64: 89-99.
    CrossRef  |  PubMed  |  Direct Link  |  
  26. Nassar, Z.D., A.F.A. Aisha, M.B.K. Ahamed, Z. Ismail, K.M. Abu-Salah, S.A. Alrokayan and A.M. Abdul Majid, 2011. Antiangiogenic properties of Koetjapic acid, a natural triterpene isolated from Sandoricum koetjaoe Merr. Cancer Cell Int., Vol. 11. 10.1186/1475-2867-11-12.
    CrossRef  |  Direct Link  |  
  27. Nassar, Z.D., A. Aisha, N. Idris, A. Khadeer and Z. Ismail et al., 2011. Koetjapic acid, a natural triterpenoid induces apoptosis in colon cancer cells. Oncol. Rep., 27: 727-733.
    CrossRef  |  PubMed  |  
  28. Aisha, A.F.A., Z.D. Nassar, M.J. Siddiqui, K.M. Abu-Salah, S.A. Alrokayan, Z. Ismail and A.M.S.A. Majid, 2011. Evaluation of antiangiogenic, cytotoxic and antioxidant effects of Syzygium aromaticum L. extracts. Asian J. Biol. Sci., 4: 282-290.
    CrossRef  |  Direct Link  |  
  29. Aisha, A.F.A., K.M. Abu-Salah, Z.D. Nassar, M.J. Siddiqui, Z. Ismail and A.M.S.A. Majid, 2011. Antitumorigenicity of xanthones-rich extract from Garcinia mangostana fruit rinds on HCT 116 human colorectal carcinoma cells. Revista Brasileira de Farmacognosia, 21: 1025-1034.
    CrossRef  |  Direct Link  |  
  30. Nassar, Z.D., A.F.A. Aisha, A.M.S. Abdul-Majid, C.S. Yeap and H.K. Fun, 2010. Koetjapic acid chloroform hemisolvate. Acta Cryst., 66: 1301-1302.
    CrossRef  |  PubMed  |  Direct Link  |  
  31. Muslim, N.S., K.W. Ng, A. Itam, Z.D. Nassa, Z. Ismail and A.M.S.A. Majid, 2010. Evaluation of cytotoxic, anti-angiogenic and antioxidant properties of standardized extracts of Strobilanthes crispus leaves. Int. J. Pharmacol., 6: 591-599.
    CrossRef  |  Direct Link  |