1. Zin, S.R.M., M.A. Alshawsh and Z. Mohamed, 2022. Multiple skeletal anomalies of sprague dawley rats following prenatal exposure to Anastatica Hierochuntica, as delineated by a modified double-staining method. Children, Vol. 9. 10.3390/children9050763.
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2. Suaidi, N.A., M.A. Alshawsh, S.Zi. Hoe, M.H. Mokhtar and S.R.M. Zin, 2022. Toxicological effects of technical xylene mixtures on the female reproductive system: A systematic review. Toxics, Vol. 10. 10.3390/toxics10050235.
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3. Lim, S.Y.M., M. Alshagga, C. Kong, M. Abdullah Alshawsh, S. AbdulRazak Alshehade and Y. Pan, 2022. CYP35 family in Caenorhabditis elegans biological processes: fatty acid synthesis, xenobiotic metabolism, and stress responses. Arch. Toxicol., 96: 3163-3174.
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4. Lim, S.Y.M., J.S.E. Loo, M. Alshagga, M.A. Alshawsh, C.E. Ong and Y. Pan, 2022. Protein-ligand identification and in vitro inhibitory effects of cathine on 11 major human drug metabolizing cytochrome P450s. Int. J. Toxicol., 41: 355-366.
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5. Lim, S.Y.M., J.S.E. Loo, M. Alshagga, M.A. Alshawsh, C.E. Ong and Y. Pan, 2022. In vitro and in silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5. Toxicol. Rep., 9: 759-768.
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6. Kamran, S., A. Sinniah, Z. Chik and M.A. Alshawsh, 2022. Diosmetin exerts synergistic effects in combination with 5-fluorouracil in colorectal cancer cells. Biomedicines, Vol. 10. 10.3390/biomedicines10030531.
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7. Kamran, S., A. Sinniah, M.A.M. Abdulghani and M.A. Alshawsh, 2022. Therapeutic potential of certain terpenoids as anticancer agents: A scoping review. Cancers, Vol. 14. 10.3390/cancers14051100.
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8. Dikeocha, I.J., A.M. Al‐Kabsi, M. Miftahussurur and M.A. Alshawsh, 2022. Pharmacomicrobiomics: Influence of gut microbiota on drug and xenobiotic metabolism. FASEB J., Vol. 36. 10.1096/fj.202101986R.
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9. Dikeocha, I.J., A.M. Al-Kabsi, H.T. Chiu and M.A. Alshawsh, 2022. Faecalibacterium prausnitzii ameliorates colorectal tumorigenesis and suppresses proliferation of HCT116 colorectal cancer cells. Biomedicines, Vol. 10. 10.3390/biomedicines10051128.
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10. Alshehade, S., M. Abdullah Alshawsh, V. Murugaiyah, M. Asif, O. Alshehade, H. Almoustafa and R.H. Al Zarzour, 2022. The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions. Life Sci., 10.1016/J.LFS.2022.120732.
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11. Al-Sayaghi, A.M., A.M. Al-Kabsi, M.S. Abduh, S.A.M. Saghir and M.A. Alshawsh, 2022. Antibacterial mechanism of action of two types of honey against Escherichia coli through interfering with bacterial membrane permeability, inhibiting proteins, and inducing bacterial DNA damage. Antibiotics, Vol. 11. 10.3390/antibiotics11091182.
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12. Al-Masawa, M.E., M.A. Alshawsh, C.Y. Ng, A.M.H. Ng and J.B. Foo et al., 2022. Efficacy and safety of small extracellular vesicle interventions in wound healing and skin regeneration: A systematic review and meta-analysis of animal studies. Theranostics, 12: 6455-6508.
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13. Abdullah Alshawsh, M., Abdulsamad Alsalahi, S. Abdalrazak Alshehade, S.A.M. Saghir, A.F. Ahmeda, R.H. Al Zarzour and A.M. Mahmoud, 2022. A comparison of the gene expression profiles of non-alcoholic fatty liver disease between animal models of a high-fat diet and methionine-choline-deficient diet. Molecules, 10.3390/molecules27030858.
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14. Abdulghani, M.A.M., S. Abdulrazak Alshehade, S. Kamran and M. Abdullah Alshawsh, 2022. Effect of monosodium glutamate on serum sex hormones and uterine histology in female rats along with its molecular docking and in-silico toxicity. Heliyon, 10.1016/j.heliyon.2022.e10967.
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15. Dikeocha, I.J., A.M. Al-Kabsi, E.E.M. Eid, S. Hussin and M.A. Alshawsh, 2021. Probiotics supplementation in patients with colorectal cancer: a systematic review of randomized controlled trials. Nutr. Rev., 10.1093/nutrit/nuab006.
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16. Chai, J.Y., V. Sugumar, M.A. Alshawsh, W.F. Wong, A. Arya, P.P. Chong and C.Y. Looi, 2021. The role of smoothened-dependent and -independent hedgehog signaling pathway in tumorigenesis. Biomedicines, Vol. 9. 10.3390/biomedicines9091188.
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17. Alshawsh, M.A., A. Alsalahi, Z. Mohamed, N. Giribabu and Z. Chik, 2021. Khat (Catha edulis) exacerbate insulin resistance in a high-fat diet/streptozotocin-induced rat model of type 2 diabetes mellitus. Metabolism, Vol. 116. 10.1016/j.metabol.2020.154546.
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18. Alsalahi, A., Z. Chik, Z. Mohamed, N. Giribabu and M.A. Alshawsh, 2021. Cathinone: An alkaloid of Catha edulis (Khat) exacerbated hyperglycemia in diabetes-induced rats. Saudi J. Biol. Sci., 28: 4633-4643.
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19. Almoustafa, H.A., M.A. Alshawsh and Z. Chik, 2021. Targeted polymeric nanoparticle for anthracycline delivery in hypoxia-induced drug resistance in metastatic breast cancer cells. Anti-Cancer Drugs, 10.1097/cad.0000000000001065.
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20. Al-Namnam, N.M., S.N. Jayash, F. Hariri, Z.A.A. Rahman and M.A. Alshawsh, 2021. Insights and future directions of potential genetic therapy for apert syndrome: a systematic review. Gene Ther., 10.1038/s41434-021-00238-w.
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21. Ganesan T., A. Sinniah, Z.A. Ibrahim, Z. Chik and M.A. Alshawsh, 2020. Annexin a1: a bane or a boon in cancer? a systematic review. Molecules 25: 3700-3700.
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22. Ganesan T., A. Sinniah, Z. Chik and M.A. Alshawsh, 2020. Punicalagin regulates apoptosis-autophagy switch via modulation of annexin a1 in colorectal cancer. Nutrients 12: 2430-2430.
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23. El-Ishaq, A., M.A. Alshawsh, K.S. Mun and Z. Chik, 2020. Biochemical and toxicological effects of methanolic extract of Asparagus africanus Lam in Sprague-Dawley rats. Biochem. Biophys. Mol. Biol., 10.7717/peerj.9138.
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24. Dikeocha I.J., A.k.M. Al-Kabsi, S. Hussin and M.A. Alshawsh, 2020. Role of probiotics in patients with colorectal cancer: a systematic review protocol of randomised controlled trial studies. BMJ Open 10.1136/bmjopen-2020-038128 http://dx.doi.org/10.1136/bmjopen-2020-038128.
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25. Cheng, K.J., M.A. Alshawsh, E.H.M. Mohamed, S. Thavagnanam, A. Sinniah and Z.A. Ibrahim, 2020. HMGB1: An overview of its versatile roles in the pathogenesis of colorectal cancer. Cell Oncol., 43: 177-193.
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26. Badroon, N., N.A. Majid, F. Al-Suede, M.N.V. and N. Giribabu et al., 2020. Cardamonin exerts antitumor effect on human hepatocellular carcinoma xenografts in athymic nude mice through inhibiting NF-κβ pathway. Biomedicines, Vol. 8. 10.3390/biomedicines8120586.
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27. Badroon N.A., N.A. Majid and M.A. Alshawsh, 2020. Antiproliferative and apoptotic effects of cardamonin against hepatocellular carcinoma hepg2 cells. Nutrients 12: 1757-1757.
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28. Alshagga M.A., Z. Mohamed, A. Seyedan, F.J.P. Ebling and M.A. Alshawsh, 2020. Khat (catha edulis) upregulates lipolytic genes in white adipose tissue of male obese mice (c57bl/6j). Journal of Ethnopharmacology 262: 113187-113187.
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29. Al-Khdhairawi, A.A.Q., Y.Y. Low, N. Manshoor, A. Arya and M. Jelecki et al., 2020. Asperginols A and B, diterpene pyrones, from an Aspergillus sp. and the structure revision of previously reported analogues. J. Nat. Prod., 83: 3564-3570.
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30. Zin, S.R.M., N.M. Kassim, Z. Mohamed, A.H. Fateh and M.A. Alshawsh, 2019. Potential toxicity effects of Anastatica hierochuntica aqueous extract on prenatal development of sprague-dawley rats. J. Ethnopharmacol., Vol. 245, No. 112180. 10.1016/j.jep.2019.112180.
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31. Seyedana, A., Z. Mohamed, M.A. Alshaggaa S. Kooshaa and M.A. Alshawsha, 2019. Cynometra cauliflora Linn. Attenuates metabolic abnormalities in high-fat diet-induced obese mice. J. Ethnopharmacol., 236: 173-182.
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32. Lim, S.Y.M., A.R.B. Azidin, Y.T. Ung, M. Al-Shagga and M.A. Alshawsh et al., 2019. Effect of 95% ethanol khat extract and cathinone on In vitro human recombinant cytochrome P450 (CYP) 2C9, CYP2D6, and CYP3A4 activity. Eurpeon. J. Drug Metab. Pharmacokinet., 44: 423-431.
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33. Koosha, S., Z. Mohamed, A. Sinniah, Z.A. Ibrahim, A. Seyedan and M.A. Alshawsh, 2019. Antiproliferative and apoptotic activities of 8-prenylnaringenin against human colon cancer cells. Life Sci., Vol. 232, No. 116633. 10.1016/j.lfs.2019.116633.
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34. Koosha, S., Z. Mohamed, A. Sinniah and M.A. Alshawsh, 2019. Investigation into the molecular mechanisms underlying the anti-proliferative and anti-tumorigenesis activities of diosmetin against HCT-116 human colorectal cancer. Sci. Rep., Vol. 9, No. 5148. 10.1038/s41598-019-41685-1.
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35. Koosha, S., Z. Mohamed, A. Sinniah and M.A. Alshawsh, 2019. Evaluation of anti-tumorigenic effects of diosmetin against human colon cancer xenografts in athymic nude mice. Molecules, Vol. 24, No. 2522. 10.3390/molecules24142522.
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36. Fateh, A.H., Z. Mohamed, Z. Chik, A. Alsalahi, S.R.M. Zin and M.A. Alshawsh, 2019. Prenatal developmental toxicity evaluation of Verbena officinalis during gestation period in female Sprague-dawley rats. Chemico-Biol. Interact., 304: 28-42.
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37. Fateh, A.H., Z. Mohamed, Z. Chik, A. Alsalahi, S.R.M. Zain and M.A. Alshawsh, 2019. Mutagenicity and genotoxicity effects of Verbena officinalis leaves extract in sprague-dawley rats. J. Ethnopharmacol., 235: 88-99.
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38. El-Ishaq, A., M.A. Alshawsh, K.S. Mun and Z. Chik, 2019. Phytochemical screening and anti-implantation activity of Asparagus africanus root extract in female sprague–dawley rats. Revista Brasileira de Farmacognosia, 29: 621-630.
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39. El-Ishaq, A., M.A. Alshawsh and Z.B. Chik, 2019. Evaluating the oestrogenic activities of aqueous root extract of Asparagus africanus Lam in female sprague-dawley rats and its phytochemical screening using gas chromatography-mass spectrometry (GC/MS). Peer J., Vol. 7, No. e7254. 10.7717/peerj.7254.
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40. Eid, E.E.M., A.S. Alanazi, S. Koosha, A.A. Alrasheedy and F. Azam et al., 2019. Zerumbone induces apoptosis in breast cancer cells by targeting αvβ3 integrin upon co-administration with TP5-iRGD peptide. Molecules, Vol. 24, No. 14. 10.3390/molecules24142554.
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41. Alsalahi, A., M.A. Alshawsh, Z. Chik and Z. Mohamed, 2018. Effect of Catha edulis (Khat) on pancreatic functions in streptozotocin-induced diabetes in male sprague-dawley rats. Exp. Anim., 67: 517-526.
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42. Al-Zarzour, R., M. Alshawsh, M. Asif, M. Al-Mansoub and Z. Mohamed et al., 2018. Adipocytokine regulation and antiangiogenic activity underlie the molecular mechanisms of therapeutic effects of Phyllanthus niruri against non-alcoholic fatty liver disease. Nutrients, Vol. 24, No. 1057. 10.3390/nu10081057.
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43. Zin, S.R.M., Z. Mohamed, M.A. Alshawsh, W.F. Wong and N.M. Kassim, 2017. Mutagenicity evaluation of Anastatica hierochuntica L. aqueous extract In vitro and In vivo., Exp. Biol. Med. (Maywood), 243: 375-385.
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44. Zin, S.R.M., Z. Mohamed, M.A. Alshawsh, W.F. Wong and N.M. Kassim, 2017. Mutagenicity evaluation of Anastatica hierochuntica L. aqueous extract In vitro and In vivo. Exp. Biol. Med. (Maywood), 243: 375-385.
    CrossRef  |  Direct Link  |  
45. Zin, S.R.M., N.M. Kassim, M.A. Alshawsh, N.E. Hashim and Z. Mohamed, 2017. Biological activities of Anastatica hierochuntica L.: A systematic review. Biomed. Pharmacother., 91: 611-620.
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46. Seyedan, A., M. Alshawsh, M. Alshagga and Z. Mohamed, 2017. Antiobesity and lipid lowering effects of Orthosiphon stamineus in high-fat diet-induced obese mice. Planta Med., 83: 684-692.
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47. Kong, W.M., Z. Mohamed, M.A. Alshawsh and Z. Chik, 2017. Evaluation of pharmacokinetics and blood-brain barrier permeability of mitragynine using in vivo microdialysis technique. J. Pharm. Biomed. Anal., 143: 43-47.
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48. Kong, W.M., Z. Chik, Z. Mohamed and M.A. Alshawsh, 2017. Physicochemical characterization of Mitragyna speciosa alkaloid extract and mitragynine using in vitro high throughput assays. Combinatorial Chem. High Throughput Screen., 20: 796-803.
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49. Almoustafa, H.A., M.A. Alshawsh and Z. Chik, 2017. Technical aspects of preparing PEG-PLGA nanoparticles as carrier for ‎chemotherapeutic ‎agents by nanoprecipitation method. Int. J. Pharm., 533: 275-284.
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50. Shwter, A.N., N.A. Abdullah, M.A. Alshawsh, H.R. El-Seedi and N.A. Al-Henhena et al., 2016. Chemopreventive effect of Phaleria macrocarpa on colorectal cancer aberrant crypt foci in vivo. J. Ethnopharmacol., 193: 195-206.
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51. Koosha, S., M.A. Alshawsh, L.C. Yeng, A. Seyedan and Z. Mohamed, 2016. An Association Map on the Effect of Flavonoids on the Signaling Pathways in Colorectal Cancer. Int. J. Med. Sci., 13: 374-385.
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52. Alshagga, M.A., M.A. Alshawsh, A. Seyedan, A. Alsalahi, Y. Pan et al., 2016. Khat (Catha edulis) and obesity: A scoping review of animal and human studies. Ann. Nutr. Metab., 69: 200-211.
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53. Alsalahi, A., M.A. Alshawsh, R. Mohamed, N.A. Alyousefi, M.A. Alshagga and A.N. Shwter et al., 2016. Conflicting Reports on the Role of the Glycemic Effect of Catha edulis (Khat): A Systematic Review and Meta-analysis. J. Ethnopharmacol., 186: 30-43.
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54. Zain, S.M., Z. Mohamed, M. Pirmohamed, H.L. Tan and M.A. Alshawsh et al., 2015. Copy number variation in exportin-4 (XPO4) gene and its association with histological severity of non-alcoholic fatty liver disease. Sci. Rep., 10.1038/srep13306.
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55. Seyedan, A., M.A. Alshawsh, M.A. Alshagga, S. Koosha and Z. Mohamed, 2015. Medicinal Plants and Their Inhibitory Activities against Pancreatic Lipase: A Review. Evidence Based Complementary Altern. Med., 10.1155/2015/973143.
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56. Amin, Z.A., H.M. Ali, M.A. Alshawsh, P.H. Darvish and M.A. Abdulla, 2015. Application of antrodia camphorata promotes rat’s wound Healing In vivo and facilitates fibroblast cell proliferation In vitro. Evidence Based Complementary Altern. Med., 10.1155/2015/317693.
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57. Shwter, A.N., N.A. Abdullah, M.A. Alshawsh, A. Alsalahi and M. Hajrezaei et al., 2014. Chemoprevention of colonic aberrant crypt foci by Gynura procumbens in rats. J. Ethnopharmacol., 151: 1194-1201.
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58. Dhiyaaldeen, S.M., M.A. Alshawsh, S.M. Salama, N.S. Alwajeeh and R. Al Batran et al., 2014. Potential activity of 3-(2-Chlorophenyl)-1-phenyl-propenonein accelerating wound healing in rats. BioMed Res. Int., Vol. 2014. 10.1155/2014/792086.
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59. Almagrami, A.A., M.A. Alshawsh, R. Saif-Ali, A. Shwter, S.D. Salem and M.A. Abdulla, 2014. Evaluation of chemopreventive effects of acanthus ilicifolius against azoxymethane-induced aberrant crypt foci in the rat colon. PloS one, Vol. 9. .
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60. Harmal, N.S., A. Khodavandi, M.A. Alshawsh, F. Jamal, Z. Sekawi, N.K. Peng and P.P. Chong, 2013. Identification and differentiation of Candida species using specific Polymerase Chain Reaction (PCR) amplification of the phospholipase B gene. Afr. J. Microbiol. Res., 7: 2159-2166.
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61. Amin, Z.A., M.A. Alshawsh, M. Kassim, H.M. Ali and M.A. Abdulla, 2013. Gene expression profiling reveals underlying molecular mechanism of hepatoprotective effect of Phyllanthus niruri on thioacetamide-induced hepatotoxicity in Sprague Dawley rats. BMC Complemt. Altern. Med., Vol. 13. 10.1186/1472-6882-13-160.
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62. Harmal, N.S., A. Khodavandi, M.A. Alshawsh, F. Jamal, Z. Sekawi, N.K. Peng and P.P. Chong, 2012. Simplex and triplex Polymerase Chain Reaction (PCR) for identification of three medically important Candida species. Afr. J. Biotechnol., 11: 12895-12902.
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63. Amin, Z.A., M.A. Abdulla, H.M. Ali, M.A. Alshawsh and S.W. Qadir, 2012. Assessment of in vitro antioxidant, antibacterial and immune activation potentials of aqueous and ethanol extracts of Phyllanthus niruri. J. Sci. Food Agric., 92: 1874-1877.
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64. Amin, Z.A., M. Bilgen, M.A. Alshawsh, H.M. Ali, A.H.A. Hadi and M.A. Abdulla, 2012. Protective role of Phyllanthus niruri extract against thioacetamide-induced liver cirrhosis in rat model. Evidence-Based Complement. Alternat. Med., Vol. 2012. 10.1155/2012/241583.
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65. Alshawsh, M.A., M.A. Abdulla, S. Ismail, Z.A. Amin, S.W. Qader, H.A. Hadi and N.S. Harmal, 2012. Free radical scavenging, antimicrobial and immunomodulatory activity of Orthosiphon stamineus. Molecules, 17: 5385-5395.
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66. Alsalahi, A., M.A. Abdulla, M. Al-Mamary, M.I. Noordin and S.I. Abdelwahab et al., 2012. Toxicological features of Catha edulis (khat) on livers and kidneys of male and female sprague-dawley rats: A subchronic study. Evidence-Based Complement. Altern. Med., 10.1155/2012/829401.
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67. Alnajar, Z.A.A., M.A. Abdulla, H.M. Ali, M.A. Alshawsh and A.H.A. Hadi, 2012. Acute toxicity evaluation, antibacterial, antioxidant and immunomodulatory effects of Melastoma malabathricum. Molecules, 17: 3547-3559.
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68. Wasman, S.Q., A.A. Mahmood, L.S. Chua, M.A. Alshawsh and S. Hamdan, 2011. Antioxidant and gastroprotective activities of Andrographis paniculata (Hempedu Bumi) in sprague dawley rats. Indian J. Exp. Biol., 49: 767-772.
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69. Fard, A.A., M. Hajrezaie, F.A. Kadir, F.A. Sefideh and S.M. Salama et al., 2011. The Effects of Combined Adiponectin-Metformin on Glucose and Lipids Levels in Mice and Acute Toxicity and Anti-Ulcerogenic Activity of Adiponectin Against Ethanol-Induced Gastric Mucosal Injuries in Rat. Molecules, 16: 9534-9552.
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70. Alshawsh, M.A., M.A. Abdulla, S. Ismail and Z.A. Amin, 2011. Hepatoprotective effects of Orthosiphon stamineus extract on thioacetamide-induced liver cirrhosis in rats. Evidence-Based Complementary Altern. Med., Vol. 2011. 10.1155/2011/103039.
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71. Alshawsh, M.A., R.A. Mothana, H.A. Al-Shamahy, S.F. Alsllami and U. Lindequist, 2007. Assessment of antimalarial activity against Plasmodium falciparum and phytochemical screening of some Yemeni medicinal plants. Evidence-Based Complementary Altern. Med., 6: 453-456.
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