Dr. Anthony E. Archibong

Associate Professor
Meharry Medical College, USA

Highest Degree
Ph.D. in Reproductive Endocrinology from Oregon State University, USA

My URL
https://livedna.org/1.9095

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Biography

Dr. Anthony Archibong received a Ph.D. from Oregon State University, in the area of Reproductive Endocrinology and conducted Post-Doctoral Research in the Department of Animal Science, North Carolina State University, Raleigh, in Embryo Physiology. He subsequently conducted another Postdoctoral Research at the Oregon National Primate Research Center, in Gamete Science. Dr. Archibong is currently an Associate Professor and Director of the Core Endocrine Laboratory in the Department of Obstetrics and Gynecology at Meharry Medical College and a Visiting Scholar in the Department of Cell and Developmental Biology at Vanderbilt University. Dr. Archibong’s expertise is in Mammalian Reproductive Biology and the Molecular Mechanism(s) of Environmental influence on Reproductive function. He is particularly interested in the adverse effects of Environmental Pollutants on the Hormones that regulate male and female Gonadal function, Gamete interaction and Preimplantation Embryo development. He served on the editorial boards, of Biology of Reproduction, Archives of Andrology and Advances in Reproduction and had served as a reviewer for Journal of Animal Science. He is currently on the editorial board of Andrology Update and a reviewer for the Biology of Reproduction, Theriogenology, Fertility Sterility, Journal of Endocrinology and Asian Journal of Andrology. He has served two terms in the UDSA Animal Reproduction Study Panel. Dr. Archibong has authored 44 peer-reviewed manuscripts, a book chapter and more than 81 abstracts in the area of Reproductive Biology/Reproductive Toxicology. He has been able to maintain continuous extramural funding for his research from federal and private sources, including a minority supplement from NIH to study sperm function in fertilization events. Dr. Archibong has served as a mentored/preceptor to Ph.D. graduate students and has supervised 10 medical students in research whose data presentations have won both Institutional and National awards. He is member of Society for the Study of Reproduction, American Society of Reproductive Medicine, National Medical Association, and member of American Association of Bioanalysts.

Area of Interest:

Animal and Veterinary Sciences
Primate Sperm Cryopreservation
Primate Sperm Physiology
Animal Biotechnology
Reproductive Physiology

Selected Publications

  1. Rekhadevi, P.V., D.L. Diggs, A.C. Huderson, K.L. Harris, A.E. Archibong and A. Ramesh, 2014. Metabolism of the environmental toxicant benzo(a)pyrene by subcellular fractions of human ovary. Hum. Exp. Toxicol., 33: 196-202.
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  2. Bruner-Tran, K.L., T. Ding, K.B. Yeoman, A. Archibong, J.A. Arosh and K.G. Osteen, 2014. Developmental exposure of mice to dioxin promotes transgenerational testicular inflammation and an increased risk of preterm birth in unexposed mating partners. PLoS ONE, Vol. 9. 10.1371/journal.pone.0105084.
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  3. Ramesh, A., A.E. Archibong, A.C. Huderson, D.L. Diggs and J.N. Myers et al., 2012. Polycyclic Aromatic Hydrocarbons. In: Veterinary Toxicology, Second Edition: Basic and Clinical Principles, Gupta, R.C. (Ed.). Elsevier Publishers, Amsterdam, The Netherlands, ISBN-13: 978-0123859266, pp: 797-809.

  4. Ghadami, M., E. El-Demerdash, D. Zhang, S.A. Salama and A.A. Binhazim et al., 2012. Bone marrow transplantation restores follicular maturation and steroid hormones production in a mouse model for primary ovarian failure. PLoS ONE, Vol. 7. 10.1371/journal.pone.0032462.
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  5. Archibong, A.E., A. Ramesh, F. Inyang, M.S. Niaz, D.B. Hood and P. Kopsombut, 2012. Endocrine disruptive actions of inhaled benzo(a)pyrene on ovarian function and fetal survival in fisher F-344 adult rats. Reprod. Toxicol., 34: 635-643.
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  6. Ramesh, A., A. Archibong, D.B. Hood, Z. Guo and B.G. Loganathan, 2011. Global Environmental Distribution and Human Health Effects of Polycyclic Aromatic Hydrocarbons. In: Global Contamination Trends of Persistent Organic Chemicals, Loganathan, B.G. and P.K.S. Lam (Eds.). Chapter 5, Taylor & Francis Publishers, Boca Raton, FL., USA., ISBN-13: 978-1439838303, pp: 97-126.

  7. Ramesh, A. and A. Archibong, 2011. Reproductive Toxicity of Polycyclic Aromatic Hydrocarbons: Occupational Relevance. In: Reproductive and Developmental Toxicology, Gupta, R.C. (Ed.). Academic Press, London, UK., ISBN-13: 978-0123820327, pp: 577-592.

  8. Ladson, G., W.C. Dodson, S.D. Sweet, A.E. Archibong and A.R. Kunselman et al., 2011. The effects of metformin with lifestyle therapy in polycystic ovary syndrome: A randomized double-blind study. Fertil. Steril., 95: 1059-1066.
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  9. Ladson, G., W.C. Dodson, S.D. Sweet, A.E. Archibong and A.R. Kunselman et al., 2011. Racial influence on the polycystic ovary syndrome phenotype: A black and white case-control study. Fertil. Steril., 96: 224-229.
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  10. Ladson, G., W.C. Dodson, S.D. Sweet, A.E. Archibong and A.R. Kunselman et al., 2011. Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: A pilot randomized double-blind study. Fertil. Steril., 95: 2595-2598.
    CrossRef  |  PubMed  |  Direct Link  |  

  11. Hood, D.B., A. Ramesh, S. Chirwa, H. Khoshbouei and A. Archibong, 2011. Developmental Toxicity of Polycyclic Aromatic Hydrocarbons. In: Reproductive and Developmental Toxicology, Gupta, R.C. (Ed.). Academic Press, London, UK., ISBN-13: 978-0123820327, pp: 593-606.

  12. Sampson, M., A.E. Archibong, A. Powell, B. Strange, S. Roberson, E.R. Hills and P. Bourne, 2010. Perturbation of the developmental potential of preimplantation mouse embryos by hydroxyurea. Int. J. Environ. Res. Public Health, 7: 2033-2044.
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  13. Ramesh, A., A.E. Archibong and M.S. Niaz, 2010. Ovarian susceptibility to benzo[a]pyrene: Tissue burden of metabolites and DNA adducts in F-344 rats. J. Toxicol. Environ. Health Part A: Curr. Issues, 73: 1611-1625.
    CrossRef  |  PubMed  |  Direct Link  |  

  14. Ghadami, M., E. El-Demerdash, S.A. Salama, A.A. Binhazim and A.E. Archibong et al., 2010. Toward gene therapy of premature ovarian failure: Intraovarian injection of adenovirus expressing human FSH receptor restores folliculogenesis in FSHR(-/-) FORKO mice. Mol. Hum. Reprod., 16: 241-250.
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  15. Jones, K.M., M.S. Niaz, C.M. Brooks, S.I. Roberson and M.P. Aguinaga et al., 2009. Adverse effects of a clinically relevant dose of hydroxyurea used for the treatment of sickle cell disease on male fertility endpoints. Int. J. Environ. Res. Public Health, 6: 1124-1144.
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  16. Harris, D.L., A.C. Huderson, M.S. Niaz, J.J. Ford, A.E. Archibong and A. Ramesh, 2009. Comparative metabolism of benzo(a)pyrene by ovarian microsomes of various species. Environ. Toxicol., 24: 603-609.
    CrossRef  |  PubMed  |  Direct Link  |  

  17. Ramesh, A., F. Inyang, D.D. Lunstra, M.S. Niaz and P. Kopsombut et al., 2008. Alteration of fertility endpoints in adult male F-344 rats by subchronic exposure to inhaled benzo(a)pyrene. Exp. Toxicol. Pathol., 60: 269-280.
    CrossRef  |  PubMed  |  Direct Link  |  

  18. Archibong, A.E., A. Ramesh, M.S. Niaz, C.M. Brooks, S.I. Roberson and D.D. Lunstra, 2008. Effects of benzo(a)pyrene on intra-testicular function in F-344 rats. Int. J. Environ. Res. Public Health, 5: 32-40.
    CrossRef  |  PubMed  |  Direct Link  |  

  19. Smith, T.L., S.T. Merry, D.L. Harris, J.J. Ford, J. Ike, A.E. Archibong and A. Ramesh, 2007. Species-specific testicular and hepatic microsomal metabolism of benzo(a)pyrene, an ubiquitous toxicant and endocrine disruptor. Toxicol. In vitro, 21: 753-758.
    CrossRef  |  PubMed  |  Direct Link  |  

  20. Brooks, C.M., K.M. Jones, M.S. Niaz, M.P. Aguinaga, E.R. Hills, V.M. Rice and A.E. Archibong, 2007. Authentication of a transgenic sickle cell mouse model with intent to study sickle cell disease-induced hypogonadism. Androl. Update, 1: 331-340.

  21. Walker, S.A., L.B. Whitten, G.B. Seals, W.E. Lee, A.E. Archibong and A. Ramesh, 2006. Inter-species comparison of liver and small intestinal microsomal metabolism of fluoranthene. Food Chem. Toxicol., 44: 380-387.
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  22. Inyang, F., A. Ramesh, P. Kopsombut, M.S. Niaz, D.B. Hood, A.M. Nyanda and A.E. Archibong, 2003. Disruption of testicular steroidogenesis and epididymal function by inhaled benzo(a)pyrene. Reprod. Toxicol., 17: 527-537.
    CrossRef  |  PubMed  |  Direct Link  |  

  23. Ramesh, A., F. Inyang and A.E. Archibong, 2002. Altered imprinting in male rats: A toxicological perspective. Adv. Reprod., 6: 156-157.

  24. Ramesh, A., D.B. Hood, F. Inyang, M. Greenwood, A.M. Nyanda, A.E. Archibong and M.E. Knuckles, 2002. Comparative metabolism, bioavailability, and toxicokinetics of benzo[ a ]pyrene in rats after acute oral, inhalation and intravenous administration. Polycyclic Arom. Compd., 22: 969-980.
    CrossRef  |  Direct Link  |  

  25. Mukherjee, S., S.K. Das, W. Kabiru, K.R. Russell and K. Greaves et al., 2002. Acute cadmium toxicity and male reproduction. Adv. Reprod., 6: 143-155.

  26. Archibong, A.E., Ramesh, A. and F. Inyang, 2002. Endocrine/environmental factors contributing to early embryonic mortality in gilts mated at first estrus. Adv. Reprod., 6: 121-128.

  27. Archibong, A.E., F. Inyang, A. Ramesh, M. Greenwood and T. Nayyar et al., 2002. Alteration of pregnancy related hormones and fetal survival in F-344 rats exposed by inhalation to benzo(a)pyrene. Reprod. Toxicol., 16: 801-808.
    CrossRef  |  PubMed  |  Direct Link  |  

  28. Ramesh, A., F. Inyang, D.B. Hood, A.E. Archibong, M.E. Knuckles and A.M. Nyanda, 2001. Metabolism, bioavailability and toxicokinetics of Benzo(α)pyrenein F-344 rats following oral administration. Exp. Toxicol. Pathol., 53: 275-290.
    CrossRef  |  PubMed  |  Direct Link  |  

  29. Freeman, M.R., A.E. Archibong, J.J. Mrotek, C.M. Whitworth, G.A. Weitzman and G.A. Hill, 2001. Male partner screening before in vitro fertilization: Preselecting patients who require intracytoplasmic sperm injection with the sperm penetration assay. Fertil. Steril., 76: 1113-1118.
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Member since January, 2016