Dr. Mahmoud Kandeel

Lecturer
Kafrelshiekh University, Egypt


Highest Degree
Ph.D. in Biomolecular Science from Gifu University, Gifu, Japan

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Area of Interest:

Pharmacology and Toxicology
Molecular Pharamcology
Drug Discovery
Molecular Parasitology
Molecular Biochemistry

Selected Publications

  1. Kandeel, M. and Y. Kitade, 2011. The substrate binding preferences of Plasmodium thymidylate kinase. Biol. Pharm. Bull., 34: 173-176.
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  2. Kandeel, M. and Y. Kitade, 2010. Substrate specificity and nucleotides binding properties of NM23H2/nucleoside diphosphate kinase homolog from Plasmodium falciparum. J. Bioenergetics Biomembr., 42: 361-369.
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  3. Kandeel, M. and Y. Kitade, 2010. Binding dynamics and energetic insight into the molecular forces driving nucleotide binding by guanylate kinase. J. Mol. Recognit., 24: 322-332.
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  4. Kandeel, M., Y. Kitamura and Y. Kitade, 2009. The exceptional properties of Plasmodium deoxyguanylate pathways as a potential area for metabolic and drug discovery studies. Nucleic Acids Symp. Ser., 53: 39-40.
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  5. Kandeel, M., T. Miyamoto and Y. Kitade, 2009. Bioinformatics, enzymologic properties and comprehensive tracking of Plasmodium falciparum nucleoside diphosphate kinase. Biol. Pharm. Bull., 32: 1321-1327.
    CrossRef  |  PubMed  |  

  6. Kandeel, M., T. Ando, Y. Kitamura, M. Abdel-Aziz and Y. Kitade, 2009. Mutational, inhibitory and microcalorimetric analyses of Plasmodium falciparum TMP kinase. Implications for drug discovery. Parasitology, 136: 11-25.
    CrossRef  |  PubMed  |  

  7. Kandeel, M., A. Kato and Y. Kitade, 2009. Thymidylate kinase: The lost chemotherapeutic target. Nucleic Acids Symp. Ser. (Oxf.), 53: 283-284.
    CrossRef  |  PubMed  |  

  8. Kandeel, M., M. Nakanishi, T. Ando, K. El-Shazly, T. Yosef, Y. Ueno and Y. Kitade, 2008. Molecular cloning, expression, characterization and mutation of Plasmodium falciparum guanylate kinase. Mol. Biochem. Parasitol., 159: 130-133.
    CrossRef  |  PubMed  |  

  9. Kandeel, M. and Y. Kitade, 2008. Molecular characterization, heterologous expression and kinetic analysis of recombinant Plasmodium falciparum thymidylate kinase. J. Biochem., 144: 245-250.
    CrossRef  |  PubMed  |  

  10. Ando, T., H. Shinohara, X. Luo, M. Kandeel and Y. Kitade, 2007. Facile synthesis of 1',2'-cis-beta-pyranosyladenine nucleosides. Carbohydr. Res., 342: 2641-2648.
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