Dr. Doha Abdou Mohamed

Professor
Department of Nutrition and Food Sciences, National Research Centre, Egypt

Highest Degree
Ph.D. in Biochemistry from Cairo University, Egypt

My URL
https://livedna.org/20.18316

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Area of Interest:

Food Science and Technology
Food Processing
Phytochemicals
Food Chemistry
Biochemistry

Selected Publications

  1. Mohamed, D., M. El-Shamarka, S. Abdelgayed and R. Mohamed, 2021. Protective effect of dietary supplements against streptozotocin-induced alzheimer`s disease in mice. J. Herbmed Pharmacol., 10: 426-435.
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  2. Mohamed, D., I. Hamed and S. Mohammed, 2021. Utilization of grape and apricot fruits by-products as cheap source for biologically active compounds for health promotion. Egypt. J. Chem., 64: 2037-2045.
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  3. Hussein, A., G. Ibrahim, M. Kamil, M. El-Shamarka, S. Mostafa and D. Mohamed 2021. Spirulina-enriched pasta as functional food rich in protein and antioxidant. Biointerface Res. Applied Chem., 11: 14736-14750.
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  4. Doha, M., M. Hoda, A. Sherein and E. Hagar, 2021. Cardioprotective potency of anthocyanin-rich extract of red cabbage against isoproterenol-induced myocardial infarction in experimental animals. J. Applied Pharm. Sci., 11: 22-30.
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  5. Al-Okbi, S.Y., D.A. Mohamed and H.F.H. Elbakry, 2021. Amelioration of oxidative stress, inflammation and liver function by nutraceuticals in rat model of hepatic cancer initiation induced by n-nitrosodiethylamine. J. Herbmed Pharmacol., 10: 194-201.
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  6. Ramadan, N.S., L.A. Wessjohann, A. Mocan, D.C. Vodnar and N.H. El-Sayed et al., 2020. Nutrient and sensory metabolites profiling of Averrhoa carambola L. (starfruit) in the context of its origin and ripening stage by GC/MS and chemometric analysis. Molecules, Vol. 25. 10.3390/molecules25102423.
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  7. Mohamed, D.A., R.S. Mohamed and K. Fouda, 2020. Anti-inflammatory potential of chia seeds oil and mucilage against adjuvant-induced arthritis in obese and non-obese rats. J. Basic Clin. Physiol. Pharmacol., Vol. 31. 10.1515/jbcpp-2019-0236.
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  8. Hussein, A.M.S., K. Fouda, F.M. Mehaya, D.A. Mohamed, A.A. Mohammad, S.S. Abdelgayed and R.S. Mohamed, 2020. Fortified vegetarian milk for prevention of metabolic syndrome in rats: impact on hepatic and vascular complications. Heliyon, Vol. 6. 10.1016/j.heliyon.2020.e04593.
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  9. Al-Okbi, S.Y., D.A. Mohamed, T.E. Hamed and E.S.K. Al-Siedy, 2020. Rice bran as source of nutraceuticals for management of cardiovascular diseases, cardio-renal syndrome and hepatic cancer. J. Herbmed Pharmacol., 9: 68-74.
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  10. Yaseen, A.A., S.Y. Al-Okbi, A.M. Hussein, D.A. Mohamed, A.A. Mohammad, K.A. Fouda and F.M. Mehaya, 2019. Potential protection from Alzheimer’s disease by wheat germ and rice bran nano-form in rat model. J. Appl. Pharm. Sci., 9: 67-76.
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  11. Mostafa, D.M., S.H.A. El-Alim, M.H. Asfour, S.Y. Al-Okbi, D.A. Mohamed, T.E.S. Hamed and G. Awad, 2019. Transdermal fennel essential oil nanoemulsions with promising hepatic dysfunction healing effect: in vitro and in vivo study. Pharm. Dev. Technol., 24: 729-738.
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  12. Mohamed, D.A., S.S. Abdelgayed, R.S. Mohamed and H.A. Essa, 2019. Impact of safflower petals and Moringa leaves extracts in experimental hyper and hypothyroidism in rats. Int. J. Pharmacol., 15: 219-228.
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  13. Mohamed, D.A., R.S. Mohamed, H.A. Essa and S.S. Abdelgayed, 2019. Protection efficiency of red radish seeds and roots against paracetamol mediated hepatotoxicity in rats. J. Herbmed. Pharmacol., 8: 302-307.
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  14. Mohamed, D.A., K.A. Fouda and R.S. Mohamed, 2019. In vitro anticancer activity of quinoa and safflower seeds and their preventive effects on non-alcoholic fatty liver. Pak. J. Biol. Sci., 22: 383-392.
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  15. Mohamed, D.A., K. Fouda, I.M. Hamed and S. s Abdelgayed, 2019. Protective effect of kumquat fruits and carrot seeds extracts against brain aging in rats. J. Herbmed Pharmacol., 8: 287-294.
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  16. Mohamed, D.A., H.A. Essa, R.S. Mohamed, 2019. Purslane and garden cress seeds as source of unconventional edible oils for prevention of hyperlipidemia. Pak. J. Biol. Sci., 22: 537-544.
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  17. Mabrok, H.B., D.A. Mohamed, O. Sytar and I. Smetanska, 2019. Biological evaluation of golden delicious apples exposure to UV lights in rats. Pak. J. Biol. Sci., 22: 564-573.
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  18. Al-Okbi, S.Y., D.A. Mohamed, T.E.S. Hamed, A.B.A. El Khalek and S.E. Mohammed, 2019. Role of probiotic mixture with and without green tea extract in prevention of hepatorenal syndrome in rat model. Pak. J. Biol. Sci., 22: 21-27.
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  19. Al-Okbi, S.Y., D.A. Mohamed, T.E. Hamed, A.M.M. Gabr and H.B. Mabrok et al., 2019. Buckwheat treatment ameliorates transforming growth factor beta-1, its receptor gene expression and biochemical parameters in experimental steatohepatitis. Int. J. Bot., 15: 5-13.
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  20. Al-Okbi, S.Y., D.A. Mohamed, T.E.S. Hamed, S.H.A. El-Alim, A.A. Kassem and D.M. Mostafa, 2018. Application of liquisolid technology for promoting the renoprotective efficacy of walnut extracts in chronic renal failure rat model. Drug Dev. Ind. Pharm., 45: 32-42.
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  21. Al-Okbi, S.Y., D.A. Mohamed, T.E. Hamed, A.A. Kassem, S.H. Abd El-Alim and D.M. Mostafa, 2017. Enhanced prevention of progression of non alcoholic fatty liver to steatohepatitis by incorporating pumpkin seed oil in nanoemulsions. J. Mol. Liq., 225: 822-832.
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  22. Al-Okbi, S.Y., D.A. Mohamed, E. Kandil, M.A. Abo-Zeid, S.E. Mohammed and E.K. Ahmed, 2017. Anti-inflammatory activity of two varieties of pumpkin seed oil in an adjuvant arthritis model in rats. Grasas y Aceites, 10.3989/gya.0796161.
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  23. Al-Okbi, S.Y., D.A. Mohamed, A.M.M. Gabr, H.B. Mabrok and T.E. Hamed, 2017. Potential Hepato- and Reno-Protective effect of artichoke callus culture and its alcohol extract in galactosamine hydrochloride treated rats. Int. J. Pharmacogn. Phytochem. Res., 9: 415-423.
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  24. Al-Okbi, S.Y., A.M. Doha, M. Abdel Fatah, K. Abdel Aal and E.M. Shaimaa, 2017. Evaluation of plant food extracts in experimental model of Alzheimer`s like disease induced by aluminum lactate in rats. J. Appl. Pharm. Sci., 7: 70-76.
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  25. Mohamed, D.A., M.M. Rashed, M. Shallan, K. Fouda and L.M. Hanna, 2016. Amelioration of benign prostate hyperplasia in rats through plant foods. Int. J. Pharmacogn. Phytochem. Res., 8: 2063-2070.

  26. Ammar, N.M., S.S. El-Hawary, D.A. Mohamed, A.M. El-Halawany and A. A. El-Anssaryet al., 2016. Estrogenic activity including bone enhancement and effect on lipid profile of luteolin-7-o-glucoside isolated from trifolium alexandrinum l. in ovariectomized rats. Phytother. Res., 30: 768-773.
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  27. Al-Okbi, S.Y., S.I. Shalaby, D.A. Mohamed, T.E. Hamed and A.M.S. Hussein, 2016. Nutrition intervention by functional foods and dietary regimen for management of nonalcoholic fatty liver disease. Der Pharma Chem., 8: 591-599.
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  28. Al-Okbi, S.Y., I.M. Hamed, D.A. Mohamed, A.M.S. Hussein and A.M. Helal, 2016. Physiochemical, sensory and biological properties of wheat-rice bran composite biscuits, crackers and pasta. Res. J. Pharm. Biol. Chem. Sci., 7: 1201-1214.

  29. Al-Okbi, S.Y., D.A. Mohamed, T.E. Hamed, M.S. Mohamed, E.M. El-Sayed and H.B. Mabrok, 2016. Prevention of hepatorenal syndrome by green tea, branched chain amino acids and mannitol in rat model. Res. J. Pharmaceut. Biol. Chem. Sci., 7: 1852-1864.
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  30. Al-Okbi, S.Y., A.M. Doha, K. Eman, K.A. Emad and E.M. Shaimaa, 2016. Antioxidant and anticancer effect of Egyptian and European pumpkin seed oil. Res. J. Pharm. Biol. Chem. Sci., 7: 574-580.

  31. Mostafa, D.M., S.H. Abd El-Alim, M.H. Asfour, S.Y. Al-Okbi, A.M. Doha and A. Gamal, 2015. Transdermal nanoemulsions of Foeniculum vulgare Mill. essential Oil: Preparation, characterization and evaluation of antidiabetic potential. J. Drug Deliv. Sci. Technol., 29: 99-106.
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  32. Mostafa, D.M., A.A. Kassem, M.H. Asfour, S.Y. Al Okbi, D.A. Mohamed and T.E.S. Hamed, 2015. Transdermal cumin essential oil nanoemulsions with potent antioxidant and hepatoprotective activities: In-vitro and in-vivo evaluation. J. Mol. Liq., 212: 6-15.
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  33. Al-Okbi, S.Y., H.H.M. Fadel and D. Mohamed, 2015. Phytochemical constituents, antioxidant and anticancer activity of Mentha citrate and Mentha longifolia. Res. J. Pharm. Biol. Chem. Sci., 6: 739-751.

  34. Al-Okbi, S.Y., D.A. Mohamed, T.E. Hamed, E.M. El-Sayed, M.S. Mohamed and H.B. Mabrok, 2015. Protective role of Nigella sativa seed meal and its alcohol extract in hepatorenal syndrome model in rats. Res. J. Pharmaceut. Biol. Chem. Sci., 6: 1355-1363.
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  35. Al-Okbi, S.Y., D.A. Mohamed and T.E. Hamed, 2015. Protection from steatohepatitis and its risk factors by plants food mixtures. Res. J. Pharm. Biol. Chem. Sci., 6: 1602-1613.
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  36. Al-Okbi, S.Y., A.M. Doha, E.H. Thanaa and E.E. Amr, 2015. Evaluation of the therapeutic effect of Nigella sativa crude oil and its blend with omega-3 fatty acids-rich oils in a modified hepatorenal syndrome model in rats. Grasas Aceites, Vol. 66, No. 4. 10.3989/gya.0245151.
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  37. Rashed, M.M., M. Shallan, D.A. Mohamed, K. Fouda and L.M. Hanna, 2014. Biological evaluation of anti-androgenic effect of some plant foods. J. Food Nutr. Res., 2: 645-651.
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  38. Mansour, S.A., D.A. Mohamed and L. Gamet-Payrastre, 2014. Effects of indirect exposure of mice pups to endosulfan via their dams during gestation and lactation periods and the ameliorative effect of vitamin E. Hum. Exp. Toxicol., 33: 911-927.
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  39. Mansour, S A., D.A. Mohamed and J.F. Sutra, 2014. Which exposure stage (gestation or lactation) is more vulnerable to atrazine toxicity? Studies on mouse dams and their pups. Toxicol. Rep., 1: 53-68.
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  40. Ammar, N.M., S.H. Mohammed, S.Y. Al-Okbi, A.M. Doha, N.K. El-Sayed, A.A. El -Anssary and M. Tom, 2014. Phytochemical and biological studies of Butia capitata Becc. Leaves cultivated in Egypt. Asian Pac. J. Trop. Biomed., 4: 456-462.
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  41. Al-Okbi, S.Y., M.A. Nagwa, A.M. Doha, M.H. Ibrahim, H.D. Ahmad, H.F. El-Bakry and M.H. Amr, 2014. Egyptian rice bran oil: Chemical analysis of the main phytochemicals. La Rivista Italiana delle Sostanze Grasse, 91: 47-58.

  42. Al-Okbi, S.Y., D.A. Mohamed, T.E. Hamed, R.S. Esmail and S.M. Donya, 2014. Plant food extracts as a source of bioactive compounds for prevention of cisplatin-induced kidney dysfunction in rats. Polish J. Food Nutr. Sci., 64: 49-57.
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  43. Al-Okbi, S.Y., D.A. Mohamed, T.E. Hamed and R.S.H. Esmail, 2014. Rice bran oil and pumpkin seed oil alleviate oxidative injury and fatty liver in rats fed high fructose diet. Pol. J. Food Nutr. Sci., 64: 127-133.
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  44. Al-Okbi, S.Y., A.M. Doha, K. Eman, K.A. Emad and E.M. Shaimaa, 2014. Functional ingredients and cardiovascular protective effect of pumpkin seed oils. Grasasy Aceites, 10.3989/gya.062813.
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  45. Al-Okbi, S.Y., A.M. Doha, E.H. Thanaa, S.H.E. Reham and M.D. Souria, 2014. Prevention of renal dysfunction by nutraceuticals prepared from oil rich plant foods. Asian Pac. J. Trop. Biomed., 4: 618-627.
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  46. Al-Okbi, S.Y., A.M. Doha, E.H. Thanaa and E.E. Amr, 2014. Protective effect of clove oil and eugenol microemulsions on fatty liver and dyslipidemia as components of metabolic syndrome. J. Med. Food, 17: 764-771.
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  47. Al‐Okbi, S.Y., A.M.S. Hussein, I.M. Hamed, D.A. Mohamed and A.M. Helal, 2014. Chemical, rheological, sensorial and functional properties of gelatinized corn-rice bran flour composite corn flakes and tortilla chips. J. Food Process. Preserv., 38: 83-89.
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  48. Mohamed, D.A., E.A. Mahmoud, S. Abdel-Moniem and M. Hassan, 2013. Anti-inflammatory and anti-arthritic activity of some spices extracts on adjuvant induced arthritis in rats. J. Applied Sci. Res., 9: 5303-5312.
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  49. Mansour, S.A., L. Gamet-Payrastre, D.A. Mohamed and M.F. Gad, 2013. Ameliorative effect of vitamin E to mice dams and their pups following exposure of mothers to atrazine during gestation and lactation periods. Sci. Lett. J., Vol. 2. .
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  50. Ammar, N.M., M.S. Hefnawy, D.A. Mohamed, F.S. Agoor and A.H. Afifi, 2013. Antiandrogenic and phytochemical evaluation of solvent and supercritical CO2 extracts of Sabal yaba fruit cultivated in Egypt. La Rivista Italiana delle Sostanze Grasse, 90: 229-235.

  51. Al‐Okbi, S.Y., D.A. Mohamed, T.E. Hamed and A.E. Edris, 2013. Potential protective effect of Nigella sativa crude oils towards fatty liver in rats. Eur. J. Lipid Sci. Technol., 115: 774-782.
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  52. Al-Okbi, S.Y., D.A. Mohamed, T.E. Hamed and A.M. Hussein, 2013. Cereals` products with red grape and walnut extracts as functional foods for prevention of kidney dysfunction. Int. J. Biol. Vet. Agric. Food Eng., 7: 289-295.
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  53. Al-Okbi, S.Y., D.A. Mohamed, A.M.S. Hussein, S. Sabry, T.E. Hamed and N.H. Ahmed, 2013. Functional foods for reduction of cardiovascular risk in type 2 diabetic patients. J. Applied Sci. Res., 9: 2072-2084.

  54. Al-Okbi, S.Y., A.M. Doha, M.H. Ibrahim, S.A. Fatma, A.M.R. Asmaa, S. El-Saed and M.H. Amr, 2013. Comparative study on Egyptian rice bran extracted by solvents and supercritical CO2. Adv. Food Sci., 35: 23-29.

  55. Mohamed, D.A., S.Y. Al-Okbi, D.M. El-Hariri and I.M. Ismael, 2012. Potential health benefits of bread supplemented with defatted flaxseeds under dietary regimen in normal and type 2 diabetic subjects. Pol. J. Food Nutr. Sci., 62: 103-108.
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  56. Al-Okbi, S.Y and A.M. Doha, 2012. Preparation and evaluation of functional foods in adjuvant arthritis. Grasasy Aceites, 63: 394-402.
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  57. Mohamed, D.A., N.M. Ammar and M.S. Hefnawy, 2011. Phytochemical and Biological studies of Butea frondosa Roxb. leaves growing in Egypt. Med. J. Islamic World Acad. Sci., 19: 173-180.
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  58. Al-Okbi, S.Y., D.A. Mohamed, S.M. Donya and A.B. Abd El Khalek, 2011. Role of Bifidobacterium bifidum and plant food extracts in improving microflora and biochemical and cytogenetic parameters in adjuvant arthritis. Grasasy Y Aceites, 62: 308-320.
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  59. Al-Okbi, S.Y and A.M. Doha, 2011. Evaluation of the anticancer effect of nutraceuticals. Adv. Food Sci., 33: 230-236.

  60. Abdel-Moein, N.M., E.A. Abdel-Moniem, D.A. Mohamed and E.A. Hanfy, 2011. Evaluation of the anti-inflammatory and anti-arthritic effects of some plant extracts. Grasas y Aceites, 62: 365-374.
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  61. Rashed, M.M., M. Shallan, D.A. Mohamed, K. Fouda and L.M. Hanna, 2010. Hypolipidemic effect of vegetable and cereal dietary mixtures from Egyptian sources. Grasas Y Aceites, 61: 261-270.

  62. Mohamed, D.A., T.E. Hamed and S.Y. Al-Okbi, 2010. Reduction in hypercholesterolemia and risk of cardiovascular diseases by mixtures of plant food extracts: A study on plasma lipid profile, oxidative stress and testosterone in rats. Grasas Aceites, 61: 378-389.
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  63. Karawya, M.S., N.M. Ammar, M.S. Hefnawy, S.Y. Al-Okbi, D.A. Mohamed and El- A.A. Ansary, 2010. Phytochemical study and evaluation of the anti-inflammatory activity of some medicinal plants growing in Egypt. Med. J. Islamic World Acad. Sci., 18: 139-150.
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  64. Hamed, T.E., D.A. Mohamed, A.A. Afifi and S.Y. Al-Okbi, 2010. Impact of intake of plant foods iron on the recovery from iron deficiency in rats. Med. J. Islamic World Acad. Sci., 18: 13-20.
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  65. Hamed, I.M., D.A. Mohamed, M.M. Hussein and S.T. El-Damhugy, 2010. Preparation and evaluation of the hypocholesterolemic effect of fermented formula. Med. J. Cairo Univ., 78: 59-66.

  66. Al-Okbi, S.Y., S.I. Shalaby, A.M. Doha and E.H. Thanaa, 2010. Evaluation of potential health benefits of two novel special foods in liver cirrhotic patients. Pol. J. Food Nutr. Sci., 60: 63-70.
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  67. Al-Okbi, S.Y., D.A. Mohamed, T.E. Hamed, A.A. Afifi and S.H.S. Mohamed, 2010. Reduction of the risk of cardiovascular diseases through dietary mixtures and probiotic. Med. J. Cairo Univ., 78: 129-137.
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  68. Mohamed, D.A and S.Y. Al-Okbi, 2009. Preparation and evaluation of two special foods in rats with liver cirrhosis. Med. J. Islamic World Acad. Sci., 17: 45-52.
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  69. El-Salam, M.H.A. and D.A. Mohamed, 2009. The protective effect of processed cheese against hyperlipidemia in rats. Dairy Sci. Technol., 89: 437-447.

  70. Ammar, N.M., S.Y. Al-Okbi, A.M. Doha and L.T. Abou El-Kassem, 2009. Antioxidant and estrogen like activity of the seed of Phoenix dactylifera palm growing in egyptian oases. Rep. Opin., 1: 1-8.

  71. Abdel Fatah, M.M., S.Y. Okbi, K.S. Ramadan, D.A. Mohamed and S.E. Mohammed, 2009. Potential beneficial effect of functional food components in Alzheimer's disease. Academia Arena, 1: 55-68.

  72. Mohamed, D.A., I.M. Hamed and S.Y. Al-Okbi, 2008. Ceratonia siliqua pods as a cheap source of functional food components. Deutsche Lebensmittel-Rundschau, 104: 25-29.

  73. Mohamed, D.A. and S.Y. Al-Okbi, 2008. Evaluation of anti-gout activity of some plant food extracts. Polish J. Food Nutr. Sci., 58: 389-395.
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  74. Mohamad, D.A., 2006. Hypotriglyceridemic effect of flaxseed in rats. Med. J. Cairo Univ., 74: 565-570.

  75. Mohammed, D.A., D.M. El-Hariri and S.Y. Al-Okbi, 2005. Impact of feeding bread enriched with flaxseed on plasma profile of hyperlipidemic rats. Pol. J. Food Nutr. Sci., 14: 431-436.
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  76. Mohamed, D.A., A.I. Ismael and A.R. Ibrahim, 2005. Studying the anti-inflammatory and biochemical effects of wheat germ oil. Deutsche Lebensmittel-Rundschau, 101: 66-72.
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  77. Mohamed, D.A. and S.Y. Al-Okbi, 2005. In vitro evaluation of antioxidant activity of different extracts of Phoenix dactylifera L. fruits as functional foods. Deutsche Lebensmittel-Rundschau, 101: 305-308.

  78. Mohamed, D.A. and S.Y. Al-Okbi, 2004. In vivo evaluation of antioxidant and anti-inflammatory activity of different extracts of date fruits in adjuvant arthritis. Pol. J. Food Nutr. Sci., 13: 397-402.
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  79. Mohamed, D.A., A.I. Ismael and H.E.A. Ibrahim, 2003. Evaluation of the anti-inflammatory and biochemical effect of flaxseed oil in inflamed rats. Kaser ElAini Med. J., 9: 79-79.

  80. Al-Okbi, S.Y., S. Kh, A.M. Abdel-Samed, M.M. Rashed and D.A. Mohamed, 2000. Nutritional status and blood anti-oxidant levels of Egyptian rheumatoid arthritis patients. Kasr El Aini Med. J., 6: 43-64.

  81. Al-Okbi, S.Y., N.M. Ammar, K.A. Soroor and D.A. Mohammed, 2000. Impact of natural oils supplements on disease activity and antioxidant state of egyptian patients with rheumatiod arthritis. Med. J. Islamic Acad. Sci., 13: 161-171.
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  82. Al-Okbi, S.Y., N.M. Ammar and D.A. Mohamed, 1999. Assessment of the safety of use of certain natural anti-inflammatory agents and their effects on nutritional status in adult and growing rats. Med. J. Islamic Acad. Sci., 12: 13-24.
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  83. Al-Okbi, S.Y., N.M. Ammar, A.M. Abdel Samed, M.M. Rashed and D.A. Mohamed, 1998. Biochemical, nutritional and pharmacological evaluation of the anti-arthritic activity of some Egyptian plants. J. Drug Res. Cairo, 22: 321-340.

  84. Ammar, N.M., S.Y. Al-Okbi and D.A. Mohamed, 1997. Study of the anti-inflammatory activity of some medicinal edible plants growing in Egypt. J. Islamic Acad. Sci., 10: 113-122.
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