Dr. Lamiaa Ahmed Ahmed Attia

Assistant Professor
Cairo University, Egypt


Highest Degree
Ph.D. in Pharmacology and Toxicology from Cairo University, Egypt

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Area of Interest:

Pharmacology and Toxicology
Pharmaceutical Analysis
Toxicology
Pharmacodynamic
Drug Analysis

Selected Publications

  1. Al-Massri, K.F., L.A. Ahmed and H.S. El-Abhar, 2019. Mesenchymal stem cells therapy enhances the efficacy of pregabalin and prevents its motor impairment in paclitaxel-induced neuropathy in rats: Role of Notch1 receptor and JAK/STAT signaling pathway. Behav. Brain Res., 360: 303-311.
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  2. Mohamed, Y.S., L.A. Ahmed, H.A. Salem and A.M. Agha, 2018. Role of nitric oxide and KATP channel in the protective effect mediated by nicorandil in bile duct ligation-induced liver fibrosis in rats. Biochem. Pharmacol., 151: 135-142.
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  3. Kandil, E.A., R.H. Sayed, L.A. Ahmed, M.A.A. El Fattah and B.M. El-Sayeh, 2018. Modulatory role of Nurr1 activation and thrombin inhibition in the neuroprotective effects of dabigatran etexilate in rotenone-induced Parkinson's disease in rats. Mol. Neurobiol., 55: 4078-4089.
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  4. Attalla, D.M., L.A. Ahmed, H.F. Zaki and M.M. Khattab, 2018. Paradoxical effects of atorvastatin in isoproterenol-induced cardiotoxicity in rats: Role of oxidative stress and inflammation. Biomed. Pharmacother., 104: 542-549.
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  5. Al-Massri, K.F., L.A. Ahmed and H.S. El-Abhar, 2018. Pregabalin and lacosamide ameliorate paclitaxel-induced peripheral neuropathy via inhibition of JAK/STAT signaling pathway and Notch-1 receptor. Neurochem. Int., 120: 164-171.
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  6. Abdel Rasheed, N.O., L.A. Ahmed, D.M. Abdallah and B.M. El-Sayeh, 2018. Paradoxical cardiotoxicity of intraperitoneally-injected epigallocatechin gallate preparation in diabetic mice. Scient. Rep., Vol. 8. 10.1038/s41598-018-25901-y.
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  7. Ahmed, L.A., S.M. Rizk and S.A. El-Maraghy, 2017. Pinocembrin ex vivo preconditioning improves the therapeutic efficacy of endothelial progenitor cells in monocrotaline-induced pulmonary hypertension in rats. Biochem. Pharmacol., 138: 193-204.
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  8. Abdel Rasheed, N.O., L.A. Ahmed, D.M. Abdallah and B.M. El-Sayeh, 2017. Nephro-toxic effects of intraperitoneally injected EGCG in diabetic mice: Involvement of oxidative stress, inflammation and apoptosis. Scient. Rep., Vol. 7. 10.1038/srep40617.
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  9. Abd El Aal, H.A., L.A. Ahmed, W.A. Hassan, H.M. Fawzy and H. Moawad, 2017. Combination of carvacrol with simvastatin improves the lipid-lowering efficacy and alleviates simvastatin side effects. J. Biochem. Mol. Toxicol., Vol. 31, No. 12. 10.1002/jbt.21981.
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  10. Ahmed, L.A., H.A. Darwish, R.M. Abdelsalam and H.A. Amin, 2016. Role of Rho kinase inhibition in the protective effect of fasudil and simvastatin against 3-nitropropionic acid-induced striatal neurodegeneration and mitochondrial dysfunction in rats. Mol. Neurobiol., 53: 3927-3938.
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  11. Mohamed, S.S., L.A. Ahmed, W.A. Attia and M.M. Khattab, 2015. Nicorandil enhances the efficacy of mesenchymal stem cell therapy in isoproterenol-induced heart failure in rats. Biochem. Pharmacol., 98: 403-411.
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  12. Ahmed, L.A., S.A. El-Maraghy and S.M. Rizk, 2015. Role of the KATP channel in the protective effect of nicorandil on cyclophosphamide-induced lung and testicular toxicity in rats. Scient. Rep., Vol. 5. 10.1038/srep14043.
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  13. El-Sawalhi, M.M. and L.A. Ahmed, 2014. Exploring the protective role of apocynin, a specific NADPH oxidase inhibitor, in cisplatin-induced cardiotoxicity in rats. Chemico-Biol. Interact., 207: 58-66.
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  14. El Sawalhi, M.M., L.A. Ahmed, M.A. Fouad and S.A. Shouman, 2014. The role of autophagy, angiogenesis and inflammatory pathways in resveratrol-induced cytotoxicity in MCF7 human breast cancer cells. Arab J. Lab. Med., 40: 21-34.

  15. Ahmed, L.A., N.I. Shehata, N.F. Abdelkader and M.M. Khattab, 2014. Tempol, a superoxide dismutase mimetic agent, ameliorates cisplatin-induced nephrotoxicity through alleviation of mitochondrial dysfunction in mice. PLoS ONE, Vol. 9. 10.1371/journal.pone.0108889.
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  16. Ahmed, L.A., A.A.Z. Obaid, H.F. Zaki and A.M. Agha, 2014. Role of oxidative stress, inflammation, nitric oxide and transforming growth factor-beta in the protective effect of diosgenin in monocrotaline-induced pulmonary hypertension in rats. Eur. J. Pharmacol., 740: 379-387.
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  17. Ahmed, L.A., A.A. Obaid, H.F. Zaki and A.M. Agha, 2014. Naringenin adds to the protective effect of L-arginine in monocrotaline-induced pulmonary hypertension in rats: Favorable modulation of oxidative stress, inflammation and nitric oxide. Eur. J. Pharm. Sci., 62: 161-170.
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  18. Mehany, H.A., A.M. Abo-Youssef, L.A. Ahmed, E.S.A. Arafa and H.A. Abd El-Latif, 2013. Protective effect of vitamin E and atorvastatin against potassium dichromate-induced nephrotoxicity in rats. Beni-Suef Univ. J. Basic Applied Sci., 2: 96-102.
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  19. Ahmed, L.A., 2013. Stem cells and cardiac repair: Alternative and multifactorial approaches. J. Regener. Med. Tissue Eng., Vol. 2. 10.7243/2050-1218-2-8.
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  20. Ahmed, L.A. and S.A. El-Maraghy, 2013. Nicorandil ameliorates mitochondrial dysfunction in doxorubicin-induced heart failure in rats: Possible mechanism of cardioprotection. Biochem. Pharmacol., 86: 1301-1310.
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  21. Ahmed, L.A., H.A. Salem, M.N. Mawsouf, A.S. Attia and A.M. Agha, 2012. Cardioprotective effects of ozone oxidative preconditioning in an in vivo model of ischemia/reperfusion injury in rats. Scand. J. Clin. Lab. Invest., 72: 345-354.
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  22. Ahmed, L.A., H.A. Salem, A.S. Attia and A.M. Agha, 2012. Comparative study of the cardioprotective effects of local and remote preconditioning in ischemia/reperfusion injury. Life Sci., 90: 249-256.
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  23. Ahmed, L.A., 2012. Protective effects of magnesium supplementation on metabolic energy derangements in lipopolysaccharide-induced cardiotoxicity in mice. Eur. J. Pharmacol., 694: 75-81.
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  24. Ahmed, L.A., H.A. Salem, A.S. Attia and A.M. Agha, 2011. Pharmacological preconditioning with nicorandil and pioglitazone attenuates myocardial ischemia/reperfusion injury in rats. Eur. J. Pharmacol., 663: 51-58.
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  25. Ahmed, L.A., H.A. Salem, A.S. Attia and A.M. Agha, 2011. Effects of different preconditioning therapies on arrhythmias and aortic blood flow in an in vivo rat model of ischaemia/reperfusion injury. Heart, Vol. 97. 10.1136/hrt.2010.213496.9.
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  26. Ahmed, L.A., H.A. Salem, A.S. Attia and M.E. El-Sayed, 2009. Enhancement of amlodipine cardioprotection by quercetin in ischaemia/reperfusion injury in rats. J. Pharm. Pharmacol., 61: 1233-1241.
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  27. Ahmed, L.A., H.A. Salem, A.S. Attia and M.E. El-Sayed, 2008. Protective effects of amlodipine, coenzyme Q10 and their combination on myocardial ischemia/reperfusion injury in rats. New Egypt. J. Med., 39: 21-32.