Dr. Hazem Mohammed Ebraheem Shaheen
ProfessorDepartment of Pharmacology, Faculty of Veterinary Medicine, Damanhour University, ElGomhoreia street, Damanhour, Egypt
Highest Degree
Ph.D. in Veterinary Pharmacology from Zagazig University, Egypt
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Biography
Dr. Hazem Mohammed Ebraheem Shaheen is currently working as Associate Professor of Veterinary Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhur University, El-Behera Governorate, Egypt. He obtained his PhD in Veterinary Pharmacology from Zagazig University in 2003. In past he worked as Researcher at Animal Health Research Institute, Tanta Provincial Laboratory, Egypt, Lecturer and Associate Professor at South Valley University, Qena, Egypt. He has published 3 books, and 21 papers/abstracts/and presentations contributed as author/co-author. His principal research interests lie in the field of Pharmacokinetics and Pharmacodynamic of Chemotherapeutic Agents. His future research plans are to investigate about Bacterial Resistance to Antimicrobials. He is member of editorial board in number of journals. He is also serving as reviewer in number of journals. He also supervised 4 Masters Degree thesis and 1 PhD thesis. He is member of Egyptian Society of Pharmacology and Experimental Therapeutics, Cairo, Egypt, Egyptian Veterinary Association of Epidemiology, Cairo, Egypt and Chnum Society for Sheep, Goat and Camel, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt.
Area of Interest:
Selected Publications
- Wasef, L., A.M.K. Nassar, Y.S. El-Sayed, D. Samak and A. Noreldin et al., 2021. The potential ameliorative impacts of cerium oxide nanoparticles against fipronil-induced hepatic steatosis. Sci. Rep., Vol. 11. 10.1038/s41598-020-79479-5.
CrossRef | Direct Link | - Saleh, H., A.M.K. Nassar, A.E. Noreldin, D. Samak and N. Elshony et al., 2020. Chemo-protective potential of cerium oxide nanoparticles against fipronil-induced oxidative stress, apoptosis, inflammation and reproductive dysfunction in male white albino rats. Molecules, Vol. 25. 10.3390/molecules25153479.
CrossRef | Direct Link | - Nassar, A.M.K., Y.M.M. Salim, K.S.A. Eid, H.M. Shaheen and A.A. Saati et al., 2020. Ameliorative effects of honey, propolis, pollen, and royal jelly mixture against chronic toxicity of sumithion insecticide in white albino rats. Molecules, Vol. 25. 10.3390/molecules25112633.
CrossRef | Direct Link | - Farag, M.R., M. Alagawany, M. Bin-Jumah, S.I. Othman and A.F. Khafaga et al., 2020. The toxicological aspects of the heat-borne toxicant 5-hydroxymethylfurfural in animals: a review. Molecules, 10.3390/molecules25081941.
CrossRef | Direct Link | - Elgeddawy, S.A., H.M. Shaheen, Y.S. Elu2010Sayed, M.A. Elaziz and A. Darwish et al., 2020. Effects of the dietary inclusion of a probiotic or prebiotic on florfenicol pharmacokinetic profile in broiler chicken. J. Anim. Physiol. Anim. Nutr., 104: 549-557.
CrossRef | Direct Link | - El-Saber Batiha, G., A. Alqahtani, O.A. Ojo, H.M. Shaheen and L. Wasef et al., 2020. Biological properties, bioactive constituents, and pharmacokinetics of some Capsicum spp. and capsaicinoids. Int. J. Mol. Sci., Vol. 21. 10.3390/ijms21155179.
CrossRef | Direct Link | - El-Hack, M.E.A., M. Alagawany, H. Shaheen, D. Samak and S.I. Othman et al., 2020. Ginger and its derivatives as promising alternatives to antibiotics in poultry feed. Animals, Vol. 10. 10.3390/ani10030452.
CrossRef | Direct Link | - Bin-Jumah, M., M.E.A. El-Hack, S.A. Abdelnour, Y.A. Hendy and H.A. Ghanem et al., 2020. Potential use of chromium to combat thermal stress in animals: a review. Sci. Total Environ., 10.1016/j.scitotenv.2019.135996.
CrossRef | Direct Link | - Batiha, G.E.S., L.M. Alkazmi, E.H. Nadwa, E.K. Rashwan, A.M. Beshbishy, H. Shaheen and L. Wasef, 2020. Physostigmine: a plant alkaloid isolated from physostigma venenosum: a review on pharmacokinetics, pharmacological and toxicological activities. J. Drug Delivery Ther., 10: 187-190.
CrossRef | Direct Link | - Amer, A.M. and M.M. Amer, 2020. Efficacy and safety of natural essential oils mixture on tick infestation in dogs. Adv. Anim. Vet. Sci., 10.17582/journal.aavs/2020/8.4.398.407.
CrossRef | Direct Link | - Alagawany, M., M.E.A. El-Hack, M.R. Farag, H.M. Shaheen, M.A. Abdel-Latif, A.E. Noreldin and A.F. Khafaga, 2020. The applications of origanum vulgare and its derivatives in human, ruminant and fish nutrition-a review. Ann. Anim. Sci., 20: 389-407.
CrossRef | Direct Link | - Wasef, L.G., H.M. Shaheen, Y.S. El-Sayed, T.I.A. Shalaby and D.H. Samak et al., 2019. Effects of silver nanoparticles on burn wound healing in a mouse model. Bio. Trace Element Res., 193: 456-465.
CrossRef | Direct Link | - Samak, D.H., Y.S. El-Sayed, H.M. Shaheen, H. Ali and M.E.A. El-Hack et al., 2019. Developmental toxicity of carbon nanoparticles during embryogenesis in chicken. Environ. Sci. Pollut. Res., (In Press). 10.1007/s11356-018-3675-6.
CrossRef | Direct Link | - El-Far, A.H., B.E. Oyinloye, M. Sepehrimanesh, M.A.G. Allah and I. Abu-Reidah et al., 2019. Date palm (phoenix dactylifera): novel findings and future directions for food and drug discovery. Curr. Drug Discovery Technol., 16: 2-10.
CrossRef | Direct Link | - Batiha, G.E.S., A.M. Beshbishy, D.S. Tayebwa, O.S. Adeyemi, H. Shaheen, N. Yokoyama and I. Igarashi, 2019. The effects of trans-chalcone and chalcone 4 hydrate on the growth of babesia and theileria. PLoS Negl. Trop. Dis., 10.1371/journal.pntd.0007030.
CrossRef | Direct Link | - Batiha, G.E.S., A.M. Beshbishy, D.S. Tayebwa, H.M. Shaheen, N. Yokoyama and I. Igarashi, 2019. Inhibitory effects of Syzygium aromaticum and Camellia sinensis methanolic extracts on the growth of Babesia and Theileria parasites. Ticks Tick-borne Dis., 10: 949-958.
CrossRef | Direct Link | - Batiha, G.E., A.H. El-Far, A.A. El-Mleeh, A.A. Alsenosy and E.K. Abdelsamei et al., 2019. In vitro study of ivermectin efficiency against the cattle tick, rhipicephalus (boophilus) annulatus, among cattle herds in El-beheira, Egypt. Vet. World, 12: 1319-1326.
CrossRef | Direct Link | - Abd El-Hack, M.E., S.A. Abdelnour, A.E.M.E. Abd El-Moneim, M. Arif and A. Khafaga et al., 2019. Putative impacts of phytogenic additives to ameliorate lead toxicity in animal feed. Environ. Sci. Pollut. Res., 26: 23209-23218.
CrossRef | Direct Link | - Umezawa, M., M. Nakamura, A.A. El-Ghoneimy, A. Onoda and H.M. Shaheen et al., 2018. Impact of diesel exhaust exposure on the liver of mice fed on omega-3 polyunsaturated fatty acids-deficient diet. Food Chem. Toxicol., 111: 284-294.
CrossRef | Direct Link | - Samak, D.H., Y.S. El-Sayed, H.M. Shaheen, H. Ali, A. Onoda, M.M. Abdel-Daim and M. Umezawa, 2018. In-ovo exposed carbon black nanoparticles altered mRNA gene transcripts of antioxidants, proinflammatory and apoptotic pathways in the brain of chicken embryos. Chem.-Biol. Interact., 295: 133-139.
CrossRef | Direct Link | - Mansour, R., M. Ibrahim and H. Shaheen, 2018. In vitro synergistic and/or antagonistic studies of norfloxacin with some disinfectants against Salmonella enteritidis. Alexandria J. Vet. Sci., 10.5455/ajvs.275828.
CrossRef | Direct Link | - Khafaga, A.F., H.M. Abu-Ahmed, A.N. El-Khamary, I.M. Elmehasseb and H.M. Shaheen, 2018. Enhancement of equid distal limb wounds healing by topical application of silver nanoparticles. J. Equine Vet. Sci., 61: 76-87.
CrossRef | Direct Link | - Elu2011Far, A., S. Munesue, A. Harashima, A. Sato and M. Shindo et al., 2018. In vitro anticancer effects of a RAGE inhibitor discovered using a structure-based drug design system. Oncol. Lett., 15: 4627-4634.
CrossRef | Direct Link | - El-Far, A., H. Shaheen, A. Alsenosy, Y. El-Sayed, S.A. Jaouni and S. Mousa, 2018. Costus speciosus: traditional uses, phytochemistry, and therapeutic potentials. Pharmacogn. Rev., 10.4103/phrev.phrev_29_17.
CrossRef | Direct Link | - Abdel-Daim, M.M., H.M. Shaheen, A.I. Abushouk, E.A. Toraih and M.S. Fawzy et al., 2018. Thymoquinone and diallyl sulfide protect against fipronil-induced oxidative injury in rats. Environ. Sci. Pollut. Res., 25: 23909-23916.
CrossRef | Direct Link | - Shaheen, H.M., A. Onoda, Y. Shinkai, M. Nakamura and A.A. El-Ghoneimy et al., 2016. The ceramide inhibitor fumonisin B1 mitigates the pulmonary effects of low-dose diesel exhaust inhalation in mice. Ecotoxicol. Environ. Saf., 132: 390-396.
CrossRef | PubMed | Direct Link | - Shaheen, H.M., 2016. Wound healing and silver nanoparticles. Global Drugs Ther., 10.15761/gdt.1000105.
CrossRef | Direct Link | - Khalil, W.F., M.S. Hazem and H.A. Rania, 2016. Ceftiofur pharmacokinetics in nile tilapia oreochromis niloticus after intracardiac and intramuscular administrations. Dis. Aquat. Org., 121: 29-35.
CrossRef | Direct Link | - Khalil, W., H. Shaheen and R. Abdou, 2016. Ceftiofur pharmacokinetics in nile tilapia Oreochromis niloticus after intracardiac and intramuscular administrations. Dis. Aquat. Org., 121: 29-35.
CrossRef | Direct Link | - El-Far, A.H., M.S. Hazem, M.M. Abdel-Daim, S.K. Al Jaouni and A.M. Shaker, 2016. Date palm (phoenix dactylifera): Protection and remedy food. Curr. Trends Nutraceuticals, .
Direct Link | - El-Far, A.H., H.A. Ahmed and H.M. Shaheen, 2016. Dietary supplementation of Phoenix dactylifera seeds enhances performance, immune response and antioxidant status in broilers. Oxidative Med. Cell. Longevity, Vol. 2016. 10.1155/2016/5454963.
CrossRef | - El-Far, A.H., A.B. Faried and M.S. Hazem, 2016. Possible anticancer mechanisms of some costus speciosus active ingredients concerning drug discovery. Curr. Drug Discovery Technol., 10.2174/1570163813666160802154403.
CrossRef | Direct Link | - Sadek, K.M. and H.M. Shaheen, 2015. The biochemical effects of ivermectin on reproductive hormones and mineral homeostasis in Baladi cows post parturition. Veterinarski Arhiv., 85: 95-103.
Direct Link | - El-Bahy, N.M., E.K. Bazh and H.M. Shaheen, 2015. Efficacy of deltamethrin, diazinon and ivermectin on Boophilus annulatus ticks (in vitro and in vivo study). Parasitol. Res., 114: 29-36.
CrossRef | Direct Link | - Abdulgayeid, M., H. Shahin, S. Foad and M.S. Ibrahim, 2015. Molecular characterization of escherichia coli isolated from buffalo calves in El-Behera governorate. Alexandria J. Vet. Sci., 47: 90-96.
CrossRef | Direct Link | - Sadek, K.M. and H.M. Shaheen, 2014. Purification and characterization of brain acetylcholinesterase of Nile tilapia Oreochromis niloticus anesthetized with clove oil or lidocaine. Jokull J., 64: 309-327.
- Sadek, K.M. and H.M. Shaheen, 2014. Biopharmacodynamical effect of clindamycin and spectinomycin combination in experimentally E. coli infected broilers. J. October 6 Univ., 2: 166-174.
Direct Link | - Sadek, K.M. and H.M. Shaheen, 2014. Biochemical efficacy of vitamin D in ameliorating endocrine and metabolic disorders in diabetic rats. Pharmaceut. Biol., 52: 591-596.
CrossRef | Direct Link | - El-Far, A.H., N.A. Bakeir and H.M. Shaheen, 2014. Anti-oxidant status for the oxidative stress in blood of Babesia infested buffaloes. Global Veterinaria, 12: 517-522.
CrossRef | Direct Link | - Shaheen, H.M., S. Morad and A. El-Goneimy, 2013. Alterations in difloxacin pharmacokinetic parameters after furosemide co-administration in goats. Int. J. Pharmacol. Clin. Trials, 25: 1122-1128.
- Shaheen, H.M. and S.H. Mohammed, 2013. Biological Evaluation of Some Chemotherapeutic Agents: Pharmacokinetic and Pharmacodynamic Interaction(s) Between Fluoroquinolones and Nonsteroidal Antiinflammatory Drugs. LAP Lambert Academic Publishing, Germany, ISBN: 9783659435324, Pages: 176.
- Shaheen, H.M. and A.H. El-Far, 2013. Evaluation the therapeutic efficacy of pefloxacin and florfenicol combination in broilers experimentally challenged by Escherichia coli. Int. J. Pharmaceut. Sci. Rev. Res., 23: 396-404.
Direct Link | - Shaheen, H., K.M. Sadek and E.K. Bazh, 2013. Evaluation of oxyclozanide and niclosamide combination as alternative antiparamphistomal therapy in buffaloes. Afr. J. Pharm. Pharmacol., 7: 2157-2166.
CrossRef | Direct Link | - Abdel-Aziz, M.I., A.A. El-Ghoneimy, H.M. Shaheen and R.S. Ahmed, 2013. Pharmacokinetic interaction of pefloxacin with diclofenac in healthy adult goats. Proceedings of the 20th International Congress of Mediterranean Federation for Health and Production of Ruminants, February 19-22, 2013, Assiut University, Egypt -.
- Abd Al-Azeem, M.W., H.M. Shaheen, K.G. Abdel Hameed and M.M. Helmy, 2013. Penicillin resistance against Staphylococcal isolates recovered from subclinical mastitis in Sohag City, Egypt. Am. J. Res. Commun., 1: 116-130.
Direct Link | - Zaki, M.M., S.A. El-Midany, H.M. Shaheen and L. Rizzi, 2012. Mycotoxins in animals: Occurrence, effects, prevention and management. J. Toxicol. Environ. Health Sci., 4: 13-28.
CrossRef | Direct Link | - Shaheen, H.M. and E.K. Bazh, 2012. Morphological response of Paramphistomum cervi to treatment with oxyclozanide and niclosamide in vitro. Egyp. J. Vet. Med. Assoc., 72: 561-574.
- El-Ghoneimy, A. A. and H.M. Shaheen, 2012. Evaluation of hematological and biochemical effects of pefloxacin/diclofenac interaction in goat. Life Sci. J., 9: 4847-4854.
- Shaheen, H.M. and M.W. El-Sheikh, 2011. Pharmacokinetics of ciprofloxacin and its interaction with diclofenac after intravenous injection in healthy rabbits. Kafrelsheikh Vet. Med. J., 9: 189-209.
- El-Sheikh, M.W. and H.M. Shaheen, 2011. Comparative pharmacokinetic studies on tulathromycin and enrofloxacin in feedlot calves. Egyp. J. Vet. Med. Assoc., 71: 543-556.
- Shaheen, H., S. El-Sheikh and A. Alkelch, 2010. Studies on Some Side Effects of Cephalosporins: Some Teratological, Male Fertility and Mutagenicity Studies in Albino Rats. LAP Lambert Academic Publishing GmbH & Co. KG., Germany, ISBN-13: 978-3-8433-8693-7, Pages: 84.
- Shaheen, H., S. El-Sheikh and A. Alkelch, 2010. Pharmacological Studies Of Some Antiseptics in Chickens: Benefits, Adverse Effects. LAP Lambert Academic Publishing GmbH & Co. KG., Germany, ISBN-13: 978-3-8433-7849-9, Pages: 128.
- El-Sheikh, W.M.A., H.M. Shaheen and A. El-Ghoneimy, 2009. Comparative pharmacokinetics of florfenicol after intravenous, intramuscular and subcutaneous injection in sheep. Assiut Vet. Med. J., 55: 100-109.
Direct Link | - El-Midany, S.A. and H.M. Shaheen, 2009. Evaluation of adding ethylene diamine tetra-acetic acid (EDTA) to iodophor on their microbicidal efficacy. Kafrelsheikh Vet. Med. J., 7: 112-128.
- Abed El Hady, A.A., A. El-Ghoneimy, H. Shaheen and O. El-Gazzar, 2009. Comparative study between butorphanol and ketamine as adjuncts for total intravenous anaesthesia in donkeys. Egyp. J. Vet. Med. Assoc., 69: 17-30.
- Abed El Hady, A.A., A. El-Ghoneimy and H. Shaheen, 2009. Comparative study of epidural anaesthesia with lidocaine, bupivacaine and lodocaine/bupivacaine mixture in donkeys. Egyp. J. Vet. Med. Assoc., 69: 19-27.
- Hassan, S.A., H. Shaheen and A. Al-Ghonamy, 2008. Characterization of some bacteria isolated from African catfish in Qena, Egypt, with studying of their antibiotic resistance. Kafrelsheikh Vet. Med. J., 6: 284-297.
- El-Ghoneimy, A., H.M. Shaheen, M.M. Mouchira, M.W. El-Sheikh and T.M. Ramadan, 2008. Some adverse effects of interaction between furosemide and enrofloxacin in albino rats. Kafrelsheikh Vet. Med. J., 6: 298-324.
- Soad, S.B., S.A. Haggag and H.M. Shaheen, 2007. The effect of prebiotic and probiotic on Clostridium perfringens infection in broiler chickens. Alexandria J. Vet. Sci., 25: 197-206.
- Shaheen, M.H., A. Hanafy and G.M. Gomaa, 2007. Interaction between probiotic and butylated hydroxytoluene in modulating aflatoxicosis in rats. Zagazig Vet. J. 35: 125-133.
Direct Link | - El-Sheikh, W.M.A. and H.M. Shaheen, 2007. Pharmacokinetic and therapeutic studies on Danofloxacin and Marbofloxacin in lactating cows. Assiut Vet. Med. J., 53: 249-261.
- Abed El Hady, A.A., A. El-Ghoneimy, H. Shaheen and O. El-Gazzar, 2007. Evaluation of some anaesthetics in catfish (Clarias gariepinus) anaesthesia: A preliminary study. Assiut Vet. Med. J., 53: 179-190.
- Haggag, S.A., S.B. Soad and H.M. Shaheen, 2005. Study the effect of probiotic on growth, serum biochemical analysis and immunity in chickens. Benha Vet. Med. J., 16: 262-271.
- Nagwa, A.S., M.A. El-Kahky, S.E. Zahran, S.S. Belih, A.M. Eisa and H.M. Shaheen, 1997. Effect of electrolyte (Almaril plus)® on broiler exposure to high environmental temperature. Proceedings of the Annual Meeting of Poultry Science Association, August 3-6, 1997, University of Georgia, Athens, Georgia, USA -.