Dr. Augustine Ocloo

Research Scientist
University of Ghana, Ghana


Highest Degree
Ph.D. in Biomedical Sciences from University of Cambridge, UK

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Area of Interest:

Biomedical Sciences
Human Nutrition
Molecualar Biology
Biochemistry
Cell Biology

Selected Publications

  1. Yeboah, R., K.P. Thomford, R. Mensah, A.A. Appiah, A.K. Thomford and A. Ocloo, 2019. A pilot study on the efficacy of an Antiaris toxicaria subsp. africana (Engl.) CC Berg based Ghanaian herbal product in the management of peripheral neuropathy. J. Pharm. Pharmacogn. Res., 7: 59-66.
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  2. Ohta, T., T. Tilkanont, F. Ayertey, M. Nakagawa and N.H. Tung et al., 2019. Establishment of a quantitative and qualitative analysis and isolation method for tetracyclic iridoids from Morinda lucida Bentham leaves. J. Pharmaceut. Biomed. Anal., 164: 475-480.
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  3. Mintah, S.O., T. Asafo-Agyei, M.A. Archer, P. Atta-Adjei Jr. and D. Boamah et al., 2019. Medicinal Plants for Treatment of Prevalent Diseases. In: Pharmacognosy: Medicinal Plants, Perveen, S. and A. Al-Taweel (Eds.). Chapter 9, InTech Publ., Rijeka, Croatia, ISBN: 978-1-83880-611-8.

  4. Mensah, E.A., B. Sarfo, E.Y. Bonney, P.K. Parbie and A. Ocloo, 2019. Symptoms of toxicity and plasma cytochrome c levels in human immunodeficiency virus-infected patients receiving anti-retroviral therapy in Ghana: A cross-sectional study. Infect. Disorder Drug Targets, (In Press). 10.2174/1871526518666181102112010.
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  5. Kumatia, E.K., S. Antwi, H. Brew-Daniels, A.A. Appiah and A. Ocloo, 2019. In vivo comparative anti-inflammatory and analgesic activities of root bark, stem and leaf extracts of Capparis erythrocarpus (Capparaceae). Pharmacogn. J., 11: 515-520.
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  6. Kumatia, E.K., F. Ayertey, A.A. Appiah and A. Ocloo, 2019. Analgesic, anti-inflammatory and anti-oxidant activities of Clausena anisata leaf and stem extracts and quantitative and qualitative phytochemical analysis of their contents. Der Pharma Chem., 11: 16-23.
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  7. Antwi, S., J. Asiedu-Larbi, O.N.K. Martey, O. Quasie and M. Boakye-Yiadom et al., 2019. Safety and effectiveness of Mist Antiaris, a herbal preparation for treatment of peripheral neuropathy. BioMed Res. Int., Vol. 2019. 10.1155/2019/2607872.
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  8. Oduro-Mensah, D., A. Ocloo, S.T. Lowor, E.Y. Bonney, L.K. Okine and N.A. Adamafio, 2018. Isolation and characterisation of theobromine-degrading filamentous fungi. Microbiol. Res., 206: 16-24.
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  9. Oduro-Mensah, D., A. Ocloo, S.T. Lowor, C. Mingle, L.K.A. Okine and N.A. Adamafio, 2018. Bio-detheobromination of cocoa pod husks: reduction of ochratoxin A content without change in nutrient profile. Microb. Cell Factor., Vol. 17. 10.1186/s12934-018-0931-x.
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  10. Ocloo, A., R. Kingsford-Adaboh and A.J. Murray, 2017. Inhibition of mitochondrial respiratory chain activity by O, O-dimethyl- and 4-O-methyl-alpinumisoflavones. J. Applied Pharmaceut. Sci., 7: 95-100.
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  11. Ocloo, A., 2017. Fundamentals of Bioenergetics. Lambert Academic Publishing, Germany, ISBN-13: 978-620-2-05940-4, Pages: 84.

  12. Adjapong, G., F.C. Mills-Robertson, M.A. Appenteng, A. Ocloo and A. Garrill, 2017. Antimicrobial activities of six selected plants against multi-drug resistant Staphylococcus aureus. Eur. J. Med. Plants, 18: 1-12.
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  13. Kumatia, E.K., K. Annan, A.R. Dickson, Y.A. Mensah and K.I. Aponsah et al., 2016. Anti-inflammatory and analgesic activities of Annickia polycarpa stem back and its constituents. Der Pharm. Lett., 8: 42-52.
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  14. Boakye-Yiadom, M., D.O. Abrokwa, C. Sepaty, R. Yeboah and A. Ocloo, 2016. Retrospective study on Mist Diodia as an antihypertensive. J. Nat. Sci. Res., 6: 37-41.
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  15. Appiah-Opong, R., I. Tuffour, G.K. Annor, A.D. Blankson-Darku and P. Cramer et al., 2016. Antiproliferative, antioxidant activities and apoptosis induction by Morinda lucida and Taraxacum officinale in human HL-60 leukemia cells. J. Global Biosci., 5: 4281-4291.
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  16. Tettey, C.O., I. Yang, A. Ocloo and H.M. Shin, 2015. Vasorelaxant and anti-inflammatory activities of the methylene chloride fraction of Foeniculum vulgare fruit extract. J. Food Biochem., 39: 55-63.
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  17. Ofori, J.A., A. Ocloo, M. Ofori, W.P. Dorleku and W.S.K. Gbewonyo, 2015. Kombucha protects against arsenic-induced protein peroxidation in rats. J. Ghana Sci. Assoc., 16: 27-35.
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  18. Ocloo, A., R. Appiah-Opong, M.A. Chama, A.A. Appiah and A.J. Murray, 2015. An in situ study on the effects of extracts of Taraxacum officinale, Paulliniia pinnata and Thonningia sanguinea on mitochondrial function. J. Food Biochem., 39: 682-688.
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  19. Tettey, C.O., A. Ocloo, P.C.N. Nagajyothi and K.D. Lee, 2014. An in vitro analysis of antiproliferative and antimicrobial activities of solvent fractions of Taraxacum officinale (Dandelion) leaf. J. Applied Pharmaceut. Sci., 4: 41-45.
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  20. Tettey, C.O., A. Ocloo, P.C. Nagajyothi and K.D. Lee, 2014. Antioxidant activity of solvent fractions of Taraxacum officinale (dandelion) leaves. J. Herbs Spices Med. Plants, 20: 329-340.
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  21. Ocloo, A., W.E. Okpattah, O. Quasie, M.M. Sakyiamah and L.K.N. Okine, 2014. Concurrent administration of aqueous extract of Cryptolepis sanguinolenta reduces the effectiveness of Artesunate against Plasmodium berghei in rats. J. Applied Pharmaceut. Sci., 4: 24-28.
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  22. Acheampong, S.M., A. Ocloo, C.V. Wutor and N.A. Adamafio, 2014. Physico-chemical characteristics of water samples from selected water bodies in and around Accra, Ghana. Pollut. Res., 33: 835-841.
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  23. Ocloo, A., L.H. Holbech and F. Gbogbo, 2013. Mitochondrial DNA density of peripheral white blood cells as a possible bio-marker of migratory status in partially migrating bird populations. Ecol. Environ. Conserv., 19: 891-897.
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  24. Abrokwah, F.K., J. Tekamah, A. Ocloo and S.T. Sackey, 2013. Studies on factors which predispose fermented cocoa (Theobroma cacao) beans to mycotoxin contamination. J. Exp. Biol. Agric. Sci., 1: 174-180.
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  25. Tettey, C.O., P.C. Nagajyothi, S.E. Lee, A. Ocloo, T.N.M. An, T.M. Sreekanth and K.D. Lee, 2012. Anti-melanoma, tyrosinase inhibitory and anti-microbial activities of gold nanoparticles synthesized from aqueous leaf extracts of Teraxacum officinale. Int. J. Cosmet. Sci., 34: 150-154.
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  26. Sakyiamah, M.M., A. Ocloo, J.P. Adjimani and A.A. Sittie, 2012. Effect of aqueous extract of Cryptolepis sanguinolenta on pharmacokinetics of chloroquine. Int. J. Drug Res. Technol., 2: 378-387.

  27. Ocloo, A., N.C. Nwokolo and N.T.K.D. Dayie, 2012. Phytochemical characterization and comparative efficacies of crude extracts of Carica papaya. Int. J. Drug Res. Technol., 2: 399-406.
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  28. Ocloo, A., M.M. Sakyiamah, P.J. Adjimani and A.A. Sittie, 2012. Aqueous extract of Cryptolepis sanguinolenta enhance cytochrome P450 1A isozyme activity in presence of Atesunate. Global J. Med. Res., 12: 15-21.
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  29. Ocloo, A. and J.T. Dongdem, 2012. Mitochondria as pharmacological targets: The discovery of novel anti-obesity mitochondrial uncouplers from Africa's medicinal plants. Afr. J. Tradit. Complement. Altern. Med., 9: 256-256.
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  30. Sakyiamah, M.M., A. Ocloo, J.P. Adjimani and A. Sittie, 2011. Effect of aqueous extract of Cryptolepis sanguinolenta on pharmacokinetics of Artesunate. Int. J. Pharmaceut. Drug Res., 3: 313-318.
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  31. Martey, O.N.K., A. Ocloo, E. Koomson and L.K.N. Okine, 2009. Assessment of Tonica, an aqueous herbal haematinic, in the modulation of rat hepatic microsomal CYP-mediated drug metabolizing enzymes: Implications for drug interactions. J. Pharmacol. Toxicol., 4: 70-78.
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  32. Dongdem, J.T., I. Soyiri and A. Ocloo, 2009. Public health significance of viral contamination of drinking water. Afr. J. Microbiol. Res., 3: 856-861.
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  33. Ocloo, A., 2008. Higher unsaturation and peroxidizability indices in caloric restricted Drosophila melanogaster than in control. J. Ghana Sci. Assoc., 10: 62-69.
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  34. Ocloo, A., I.G. Shabalina, J. Nedergaard and M.D. Brand, 2007. Cold-induced alterations of phospholipid fatty acyl composition in brown adipose tissue mitochondria are independent of uncoupling protein-1. Am. J. Physiol.-Regul. Integr. Comp. Physiol., 293: R1086-R1093.
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  35. Ocloo, A., 2006. Dietary fatty acids alter mitochondrial phospholipid fatty acyl composition and proton leak in Drosophila melanogaster. Biokemistri, 18: 111-119.
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  36. Ocloo, A., 2005. Uncoupling proteins 2 and 3 alter mitochondrial membrane phospholipid fatty acyl composition in yeast. Biokemistri, 17: 83-94.
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  37. Brand, M.D., J.L. Pakay, A. Ocloo, J. Kokoszka, D.C. Wallace, P.S. Brookes and E.J. Cornwall, 2005. The basal proton conductance of mitochondria depends on adenine nucleotide translocase content. Biochem. J., 392: 353-362.
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  38. Brand, M., N. Turner, A. Ocloo, P. Else and A. Hulbert, 2003. Proton conductance and fatty acyl composition of liver mitochondria correlates with body mass in birds. Biochem. J., 376: 741-748.
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  39. Bishop, T., A. Ocloo and M.D. Brand, 2002. Structure and function of mitochondria in Hepatopancreas cells from metabolically depressed snails. Physiol. Biochem. Zool., 75: 134-144.
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