Dr. Lucky Lebgbosi Nwidu

Senior Lecturer
University of Port Harcourt, Nigeria

Highest Degree
Ph.D. in Pharmacology from University of Uyo, Nigeria

My URL
https://livedna.org/234.15121

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Area of Interest:

Pharmacology and Toxicology
Natural Product Pharmacology
Public Health Pharmacy
Acetylcholinesterase
Hepatotoxicity

Selected Publications

  1. Nwidu, L.L. and Y.I. Oboma, 2019. Telfairia occidentalis (cucurbitaceae) pulp extract mitigates rifampicin-isoniazid-induced hepatotoxicity in an in vivo rat model of oxidative stress. J. Integr. Med., 17: 46-56.
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  2. Nwidu, L.L. and Y.I. Oboma, 2019. Nauclea latifolia stem-bark extract protects the prefrontal cortex from valproic acid - induced oxidative stress in rats: effect on b-cell lymphoma and neuron specific enolase protein expression. GSC Bio. Pharm. Sci., 7: 44-61.
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  3. Nwidu, L.L. and Y.I. Oboma, 2019. Nauclea latifolia (rubiaceae) stem-bark hydromethanolic extract abrogates a histone deacetylase inhibitor - induced multifocal toxicity in albino rats. Eur. J. Medic. Plants, 10.9734/ejmp/2019/v27i430121.
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  4. Nwidu, L.L. and Y.I. Oboma, 2019. Musanga cecropioides (urticaceae) stem-bark mitigates sodium valproate-induced pantoxicity derangement in albino rats. GSC Bio. Pharm. Sci., 7: 6-27.
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  5. Nwidu, L., P. Alikwe, E. Elmorsy and W. Carter, 2019. An investigation of potential sources of nutraceuticals from the Niger Delta areas, Nigeria for attenuating oxidative stress. Medicines, 10.3390/medicines6010015.
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  6. Nwidu, L.Y., Y.I. Oboma, E. Elmorsy and W.G. Carter, 2018. Hepatoprotective effect of hydromethanolic leaf extract of Musanga cecropioides (Urticaceae) on carbon tetrachloride-induced liver injury and oxidative stress. J. Taibah Univ. Med. Sci., 13: 344-354.
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  7. Nwidu, L.L., Y.I. Oboma, E. Elmorsy and W.G. Carter, 2018. Alleviation of carbon tetrachloride-induced hepatocellular damage and oxidative stress with a leaf extract of Glyphae brevis (Tiliaceae). J. Basic Clin. Physiol. Pharmacol.,Vol 29 10.1515/jbcpp-2017-0058.
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  8. Nwidu, L.L., E. Elmorsy, Y.I. Oboma and W.G. Carter, 2018. Hepatoprotective and antioxidant activities of spondias mombin leaf and stem extracts against carbon tetrachloride-induced hepatotoxicity. J. Taibah Uni. Med. Sci., 13: 262-271.
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  9. Nwidu, L.L., E. Elmorsy and W.G. Carter, 2018. In vitro anti-cholinesterase and anti-oxidant activity of three standardised polyherbal products used for memory enhancing in ethnomedicine of south-east Nigeria. Malaysian J. Med. Sci., 25: 27-39.
    CrossRef  |  Direct Link  |  

  10. Nwidu, L.L. and R.E. Teme, 2018. Hot aqueous leaf extract of Lasianthera africana (icacinaceae) attenuates rifampicin-isoniazid-induced hepatotoxicity. J. Integr. Med., 16: 263-272.
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  11. Nwidu, L., E. Elmorsy, J. Aprioku, I. Siminialayi and W. Carter, 2018. In vitro anti-cholinesterase and antioxidant activity of extracts of Moringa oleifera plants from rivers state, niger delta, Nigeria. Medicines, 10.3390/medicines5030071.
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  12. Labisso, W., A.C. Raulin, L. Nwidu, A. Kocon and D. Wayne et al., 2018. The loss of u03b1- and u03b2-tubulin proteins are a pathological hallmark of chronic alcohol consumption and natural brain ageing. Brain Sci., 10.3390/brainsci8090175.
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  13. Nwidu, L.L., E. Elmorsy, J. Thornton, B. Wijamunige, A. Wijesekara, R. Tarbox and W.G. Carter, 2017. Anti-acetylcholinesterase activity and antioxidant properties of extracts and fractions of Carpolobia lutea. Pharm. Biol., 55: 1875-1883.
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  14. Lucky, L.N. and L.O. Temitayo, 2017. Hematotoxicity status of lead and three other heavy metals in cow slaughtered for human consumption in jos, Nigeria. J. Toxicol. Environ. Health Sci., 9: 83-91.
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  15. Okokon, J.F., K. Davis and L.L. Nwidu, 2016. Anti-inflammatory and antinociceptive activities of Solenostemon monostachyus aerial part extract in mice. Avicenna J. Phytomed., 6: 284-294.
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  16. Nwidu, L.L., E. Elmorsy and W.G. Carter, 2016. In-vitro Anticholinesterases screening and antioxidant activity of three standardized herbal products used in ethnomedicine of South-East Nigeria. Nigeria. FASEB J., .
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  17. Nwidu, L.L., B. Airhihen and A. Ahmadu, 2016. Anti-inflammatory and antinociceptive profile of Stem-bark extract and factions of C. lutea (Polygalaceae). J. Basic. Clin. Pharma., 8: 25-32.

  18. Elmorsy, E., S.M. Attalla, E. Fikry, A. Kocon and R. Turner et al., 2016. Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics. Hum. Exp. Toxicol., (In Press). 10.1177/0960327116660751.
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  19. El-Morsy, M., A. Al-Ghafari, S.M. Attalla and L.L. Nwidu, 2016. Role of oxidative stress in antituberculous drugs (individuals and combined) cytotoxicity in HepG2 cells. Malays. Appl. Biol., 45: 151-158.

  20. Okokon, J.E., L.U. Amazu and L.L. Nwidu, 2015. Antidiabetic and hypolipidaemic activities of Solenostemon monostachyus. J. Herbal Drugs, 6: 85-92.
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  21. Okokon, J.E., B.S. Antia and L.L. Nwidu, 2015. Antidiarrhoeal activity of stem extract and fractions of Homalium letestui. Int. J. Phytother., 5: 86-89.
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  22. Nwidu, L.L., P.A. Nwafor and W. Vilegas, 2015. The aphrodisiac herb Carpolobia: A biopharmacological and phytochemical review. Pharmacogn. Rev., 9: 132-139.
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  23. Nwidu, L.L., M. Bariweni and I. Kamenebali, 2015. Diarrheal protective effects of Carpolobia lutea hot aqueous stem-bark extract in rats. Eur. J. Biomed. Pharm. Res., 2: 1-19.

  24. Elmorsy, E., M.M. Salama, M. Abdelsalam, L.L. Nwidu, M.E.S. Zaki, M. El-Bendary and A.M. Aggour, 2015. Liver functions derangement among substances abusers. Int. J. Med. Phar. Sci., 6: 19-26.

  25. Ebeshi, B.U., A.I. Ifeanyi and L.L. Nwidu, 2015. The effects of A lchornea cordifolia on the pharmacokinetics of ciprofloxacin in rats. World J. Pharm. Res., 4: 58-69.

  26. Amazu, L.U., J.E. Okokon and L.L. Nwidu, 2015. Antiulcerogenic activity of stem extract and fractions of Homalium letestui. J. Herbal Drugs, 6: 51-57.
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  27. Nwidu, L.L., O.O. Ukiris, C.M. Rodrigues and W. Vilegas, 2014. Antidiarrheal mechanism and ionic profile of Carpolobia lutea ethanolic stem-bark extract in rats. Afr. J. Tradit. Complement. Altern. Med., 11: 257-263.
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  28. Nwidu, L.L., J.S. Aprioku and F.H. Guluye, 2014. Study on radical scavenging and gastroprotective effects of ethanolic stem-bark extract of carpolobia lutea in rodents. World J. Pharm. Res., 3: 73-88.
    Direct Link  |  

  29. Nnoli, M., N.L. Lebgbosi and C.O. Nwabuko, 2014. Toxicological investigation of acute carbon monoxide poisoning in‎ four occupants of a fuming sport utility vehicle‎. Iran. J. Toxicol., 7: 973-976.
    Direct Link  |  

  30. Baba, H., C.O. Usifoh and L.L. Nwidu, 2014. Synthesis of some long chain Fatty Acid amide derivatives with possible anti-inflammatory and anti-nociceptive effect. West Afr. J. Pharm., 25: 1-8.
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  31. Aprioku, J.S., L.L. Nwidu and C.N. Amadi, 2014. Evaluation of toxicological profile of ibuprofen in Wistar albino rats. Am. J. Biomed. Sci., 6: 32-40.
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  32. Nwidu, L.L., O.A. Victor, B. Bagbi and O. Nwolu, 2013. Primary health care status: Evaluation of MDG‘s 4, 5, and 6 in a cosmopolitan LGA in Nigeria. J. Pharm. Biomed. Sci., 26: 336-344.

  33. Nnoli, M., L.L. Nwidu, P.A. Nwafor and I. Chukwuonye, 2013. Toxicological investigation of acute cyanide poisoning of a 29-year-old man: A case report. Iran. J. Toxicol., 7: 831-835.
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  34. Nwidu, LL., P.A. Nwafor and W. Vilegas, 2012. Antiulcer effect of ethyl acetate fraction of Carpolobia lutea Leaf. J. Applied Pharm. Sci., 2: 233-242.

  35. Nwidu, L.L., P.A. Nwafor and W. Vilegas, 2012. Neuropharmacological screening and isolation of cinnamoyl-& coumaroul-glucosides from leaf fraction of Carpolobia lutea G. Don (Polygalaceae). Ind. J. Novel. Drug Delivery, 4: 28-37.

  36. Nwidu, L.L., P.A. Nwafor and W. Vilegas, 2012. Antimicrobial activity of Carpolobia lutea extracts and fractions. Afr. J. Tradit. Complement. Altern. Med., 9: 323-328.
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  37. Nwidu, L.L., M. Nnoly and P.A. Nwafor, 2012. Sub-chronic oral toxicity profile of Carpolobia lutea leaf fractions in rats. Int. J. Bioassays, 01: 42-51.

  38. Nwidu, L.L., E.M. Cilli and W. Vilegas, 2012. Amino acid, antioxidant and ion profiles of Carpolobia lutea leaf (Polygalaceae). Trop. J. Pharmaceut. Res., 11: 807-813.
    CrossRef  |  Direct Link  |  

  39. Nwidu, L.L., A.S. Oluwaseyi and P.A. Nwafor, 2012. Acute and Sub-acute Toxicity profile of Carpolobia lutea leaf extract in rats. J. Pharmacol. Toxicol., 7: 140-149.

  40. Nwidu, L.L. and P.A. Nwafor, 2012. Anti-inflammatory and antipyretic effect of Carpolobia lutea leaf extract in rodents. Int. Res. J. Pharm., 3: 154-160.

  41. Nwidu, L.L., P.A. Nwafor, V.C. da Silva, C.M. Rodrigues, L.C. dos Santos, W. Vilegas and R.L. Nunes-de-Souza, 2011. Anti-nociceptive effects of Carpolobia lutea G. Don (Polygalaceae) leaf fractions in animal models. Inflammopharmacology, 19: 215-225.
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  42. Nwidu, L.L., G.E. Essien, P.A. Nwafor and W. Vilegas, 2011. Antidiarrheal mechanism of Carpolobia lutea leaf fractions in rats. Pharmaceut. Biol., 49: 1249-1256.
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  43. Nwidu, L.L., B. Oveh and P.S.K. Abanee, 2009. The prevalence of tuberculosis and leprosy in primary health care levels in rivers state, Nigeria. Biomed. Pharmacol. J., 1: 265-274.
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  44. Nwidu, L.L. and P.A. Nwafor, 2009. Gastroprotective effects of leaf extracts of Carpolobia lutea (polygalaceae) G. Don. in rats. Afr. J. Biotechnol., 8: 12-19.
    Direct Link  |  

  45. Essien, G.E., L.L. Nwidu and P.A. Nwafor, 2009. Anti-inflammatory and analgesic potential of methanolic extract of Emilia sonchifolia (Compositae) leaves in rodents. Afr. J. Biomed. Res., 12: 199-207.

  46. Nwidu, L.L., T. Okoriye and J.F. Eniojukan, 2008. Artisan reported efficacy outcome of ibuprofen in mild to moderate body pains in Niger delta areas, Nigeria. J. Pharm. Res., 2: 163-169.

  47. Nwidu, L.L., J.F. Eniojukan and A.C. Oparah, 2008. Patient -reported outcome of therapy with two brands of ibuprofen. Pharm. Prac., 6: 142-147.

  48. Nwidu, L.L., B. Oveh, T. Okoriye and N.A. Vaikosen, 2008. Comparative in vitro study of Ibuprofen tablets used as anti-inflammatory and analgesics in Niger Delta Areas. Asian J. Pharm. Clin. Res., 1: 27-32.

  49. Nwidu, L.L., B. Oveh, T. Okoriye and N.A. Vaikosen, 2008. Assessment of the water quality and prevalence of water borne diseases in Amassoma, Niger Delta, Nigeria. Afri. J. Biotechnol., 7: 2993-2997.
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  50. Okokon, J.E., A.L. Bassey and L.L. Nwidu, 2007. Antidiabetic and hypolipidaemic effects of ethanolic root extract of Setaria megaphylla. Int. J. Pharmacol., 3: 91-95.
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  51. Nwidu, L.L. and O.O. Ebong, 2007. Prevalence and treatment of aquagenic pruritus amongst private borehole water users in port harcourt, Nigeria. West Afr. J.. Pharm., 20: 51-57.

  52. Nwafor, P.A., L.L. Nwidu and B. Oveh, 2007. Evaluation of Potencies of some commonly anti-inflammatory and analgesic drugs in South-eastern parts of nigeria in rodents Nigerian. J. Exp. Applied Biol., 8: 105-110.

  53. Grace, A.E., E.O Jude, L.L. Nwidu and S.A. Bassey, 2007. Evaluation of in vivo antiplasmodial activity of ethanolic leaf extract of Lasianthera Africana. Res. J. Pharmacol., 1: 30-33.
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  54. Okokon, J.E., L.I. Nwidu and G.A. Essiet, 2006. Evaluation of in-vivo antiplasmodial activity of Aspilia Africana. Int. J. Pharmacol., 2: 348-351.

  55. Nwidu, L.L., O.O. Ebong and B.A. Wariso, 2006. The health implication of under-groundwater used for domestic consumption in an oil producing area (Port Harcourt City), Nigeria. J. Med. Pharm. Sci, 2: 39-45.

  56. Nwidu, L.L., O.O. Ebong and B.A. Wariso, 2006. Report of assessment of bacteria flora of health significance in private borehole water supply in Port Harcourt city, Nigeria. J. Res. Biosci, 2: 13-17.

  57. Jimmy, E.O., I.F. Usoh, O.E. Etim and L.L. Nwidu, 2006. Haematological response in comparative doses of chloroquine, fansidar, ladap, amalar and cotexcin. J. Med. Pharm. Sci., 2: 1-4.

  58. Antia, B.S., J.E. Okokon, L.L. Nwidu and C.L. Jackson, 2006. Effect of subchronic administration of ethanolic stembark extract of Mammea africana sabine on haematological and biochemical parameters of rats. Afr. J. Biomed. Res., 9: 129-132.
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