Dr. Chukwunonso ECC Ejike

Senior Lecturer
Federal University Ndufu-Alike, Nigeria

Highest Degree
PostDoc. in Molecular Nutrition from University of Guelph, Canada

My URL
https://livedna.org/234.16212

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Biography

I have an avid interest in diseases linked to the metabolic syndrome, and the use of medicinal foods to ameliorate chronic diseases.

Area of Interest:

Pharmacology and Toxicology
Pharmaceutical Biology
Clinical Nutritionist
Ethnopharmacology
Obesity Research

Selected Publications

  1. Ukegbu, P.O., A.C. Uwaegbute, C.A. Echendu, C.E.C.C. Ejike and J.U. Anika-Elekeh et al., 2017. Obesity and associated factors in young adults attending tertiary institutions in South-Eastern Nigeria. South Afr. J. Clin. Nutr., 30: 43-48.
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  2. Rajendran, S.R.C.K., C.E.C.C. Ejike, M. Gong, W. Hannah and C.C. Udenigwe, 2017. Preclinical evidence on the anticancer properties of food peptides. Protein Peptide Lett., 24: 126-136.
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  3. Ejike, C.E.C.C., S.A. Collins, N. Balasuriya, A.S. Swanson, M. Beth and C.C. Udenigwe, 2017. Prospects of microalgae proteins in producing peptide-based functional foods for promoting cardiovascular health. Trends Food Sci. Technol., 59: 30-36.
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  4. Ejike, C.E.C.C., C.O. Eferibe and F.O. Okonkwo, 2017. Concentrations of some heavy metals in underground water samples from a Nigerian crude oil producing community. Environ. Sci. Pollut. Res., 24: 8436-8442.
    CrossRef  |  

  5. Ejike, C.E.C.C., 2017. Prevalence of hypertension in Nigerian children and adolescents: A systematic review and trend analysis of data from the last four decades. J. Trop. Paediatr., 63: 229-241.
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  6. Ejike, C.E.C.C. and P.O. Ukegbu, 2017. Not a straitjacket affair: Anthropometrically-derived obesity index-correlates of elevated blood pressure among University undergraduates. Med. Sci., Vol. 5. 10.3390/medsci5020009.
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  7. Tittikpina, N.K., C.E.C.C. Ejike, E. Castelluci-Estevam, M.J. Nasim and S. Griffin et al., 2016. Togo to go: Products and compounds derived from local plants for the treatment of diseases endemic in sub-Saharan Africa. Afr. J. Trad. Complement. Altern. Med., 13: 85-94.
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  8. Ijeh, I.I., I.N. Eke, C.C. Ugwu and C.E.C.C. Ejike, 2016. Myco-nourishment from the wild: Chemical analyses of the nutritional and amino acid profile of Termitomyces robustus harvested from Uzuakoli, Nigeria. Nat. Prod. Chem. Res., Vol. 4. 10.4172/2329-6836.1000225.
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  9. Ejike, C.E.C.C., 2016. Malnutrition affects the urban-poor disproportionately: A study of Nigerian children of different socioeconomic statuses. Children, Vol. 3. 10.3390/children3040017.
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  10. Egedigwe, C.A., I.I. Ijeh, P.N. Okafor and C.E.C.C. Ejike, 2016. Aqueous and methanol extracts of Vernonia amygdalina leaves exert their anti-obesity effects through the modulation of appetite-regulatory hormones. Pharm. Biol., 54: 3232-3236.
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  11. Egedigwe, C.A., C.E.C.C. Ejike, I.I. Ijeh, G.I. Onwuka, U. Herbert and A. Asumugha, 2016. Anti- obesity potentials of aqueous and methanol extracts of Vernonia amygdalina Del. leaves in high-fat diet fed rats. Afr. J. Trad. Complement. Altern. Med., 13: 86-93.
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  12. Al-Marby, A., C.E.C.C. Ejike, M.J. Nasim, N.A. Awadh-Ali, R.A. Al-Badani, G.M.A. Alghamdi and C. Jacob, 2016. Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula. J. Intercultural Ethnopharmacol., 5: 114-121.
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  13. Ejike, C.E.C.C., N.K. Uka and S.O. Nwachukwu, 2015. Diabetes and pre-diabetes in adult Nigerians: Prevalence, and correlations of blood glucose concentrations with measures of obesity. Afr. J. Biochem. Res., 9: 55-60.
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  14. Ejike, C.E.C.C., K.C. Eze and C.E. Okpan, 2015. Erectile dysfunction and hypertension among adult males in Umudike, Nigeria: A study of prevalence and relationships. Asian J. Scient. Res., 8: 315-323.
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  15. Ejike, C.E.C.C., E.O. Mbaraonye and E. Enyinnaya, 2015. Fatty acid saturation profiles and lipid contents of muscles from six popular culinary fish species sold in Umuahia, Nigeria. J. Med. Nutr. Nutraceuticals, 4: 91-94.
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  16. Ejike, C.E.C.C., A.K. Okezie, E.V. Opara and F.C. Oche, 2015. Glycaemic indexes of selected carbohydrate-based staple foods, and the effects of some culinary vegetables on post-prandial glycaemia. Niger. J. Biochem. Mol. Biol., 30: 36-43.

  17. Ejike, C.E.C.C., 2015. Body shape dissatisfaction is a normative discontent in a young-adult Nigerian population: A study of prevalence and effects on health-related quality of life. J. Epidemiol. Global Health, 5: S19-S26.
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  18. Ejike, C.E.C.C., 2015. An unholy triad: Coexistence of symptoms of benign prostatic hyperplasia and erectile dysfunction in an overweight/obese population. J. Obesity, Vol. 1. .
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  19. Ejike, C.E.C.C. and K.C. Eze, 2015. Prevalence of symptoms of benign prostatic hyperplasia in Umudike and its relationship with measures of obesity. Asian J. Clin. Nutr., 7: 1-8.
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  20. Ejike, C.E.C.C. and I.C. Ohanenye, 2015. Validation of the Ejike-Ijeh equations for the estimation of body fat percentage: A random cross-sectional study in adult Nigerians. Biokemistri, 27: 63-67.
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  21. Chukwunonso E.C.C. Ejike, Chinwendu E. Ikwuegu, Ruth C. Abalogu 2015. Obesity Determined by Different Measures and its Impact on the Health-Related Quality of Life of Young-Adult Nigerians Asian J. Clin. Nutr., 7: 64-75.
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  22. Ukegbu, P.O., A.A. Iwelumor, C.A. Echendu, J.U. Anyika-Elekeh and V.U. Asumugha et al., 2014. Assessment of lipid profile of a group of undergraduates in Michael Okpara university of agriculture, Umudike, Abia State, Nigeria. Niger. J. Nutr. Sci., 35: 11-18.

  23. Okonkwo, F.O., C.E.C.C. Ejike, U. Berger, C. Schmaling, R. Schierl and K. Radon, 2014. Workplace exposure to polycyclic aromatic hydrocarbons (PAHs): A review and discussion of regulatory imperatives for Nigeria. Res. J. Environ. Toxicol., 8: 98-109.
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  24. Ejike, C.E.C.C., 2014. This stroke was sent…: Stroke-related illness concepts and attendant health-seeking behaviours of educated Nigerians. Biokemistri, 26: 69-75.
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  25. Ejike, C.E.C.C., 2014. Child and adolescent obesity in Nigeria: A narrative review of prevalence data from three decades (1983-2013). J. Obes. Metab. Res., 1: 171-179.
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  26. Okonkwo, F.O., C.E.C.C. Ejike, A.N. Anoka and I.N.E. Onwurah, 2013. Toxicological studies on the short term exposure of Clarias albopunctatus (Lamonte and Nichole 1927) to sub-lethal concentrations of Roundup. Pak. J. Biol. Sci., 16: 939-944.
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  27. Ijeh, I.I., A.P. Amadi and C.E.C.C. Ejike, 2013. Improvement of glucose tolerance in rats fed diets incorporated with Vernonia amygdalina leaves. Biokemistri, 25: 1-5.
    Direct Link  |  

  28. Ejike, C.E.C.C., S.O. Awazie, P.A. Nwangozi and C.D. Godwin, 2013. Synergistic postprandial blood glucose modulatory properties of Vernonia amygdalina (Del.), Gongronema latifolium (Benth.) and Occimum gratissimum (Linn.) aqueous decoctions. J. Ethnopharmacol., 149: 111-116.
    CrossRef  |  PubMed  |  Direct Link  |  

  29. Ejike, C.E.C.C., N.H. Onwuka and O.G. Onyemelie, 2013. Added-on salt, socio-economic status and blood pressure in Nigerian adolescents. J. Pharm. Allied Sci., 10: 1863-1872.
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  30. Ejike, C.E.C.C., M. Gong and C.C. Udenigwe, 2013. Phytoalexins from the Poaceae: Biosynthesis, function and prospects in food preservation. Food Res. Int., 52: 167-177.
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  31. Ejike, C.E.C.C., J.N. Onyemairo and I.A. Onukogu, 2013. Co-existence of child and adolescent obesity and thinness in a city in Nigeria: Comparison of results derived from different reference standards. Int. J. Nutr. Pharmacol. Neurol. Dis., 3: 276-281.
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  32. Ejike, C.E.C.C., A.J. Amadi, N.R. Nnabuko, O.O. Kalu and N.S. Egbom, 2013. Concentrations of sodium in and moisture content of, retail bread samples sold in Umuahia metropolis, Nigeria. Int. J. Curr. Biochem. Res., 1: 1-8.
    Direct Link  |  

  33. Ejike, C.E.C.C., 2013. Obesity and hypertension in children and adolescents: Developing new tools for the diagnosis of two global pediatric challenges. J. Med. Sci., 13: 151-159.
    CrossRef  |  

  34. Ejike, C.E.C.C., 2013. Cardio-metabolic and prostatic diseases in Nigeria: Isn’t what’s good for the goose good for the gander? Biokemistri, 25: 140-145.
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  35. Ejike, C.E.C.C., 2013. Association between anxiety and obesity: A study of a young-adult Nigerian population. J. Neurosci. Rural Pract., 4: S13-S18.
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  36. Ejike, C.E.C.C. and F.Z. Yin, 2013. Blood pressure-to-height ratio simplifies the diagnosis of hypertension in Nigerian children. J. Trop. Pediatr., 59: 160-161.
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  37. Ahaiwe, U.E., I.I. Ijeh and C.E.C.C. Ejike, 2013. Methanolic extract of Vernonia amygdalina may protect against experimental benign prostatic hyperplasia in an albino Wistar rat model. J. Med. Aromatic Plant Sci., 35: 115-120.

  38. Ejike, C.E.C.C., I.P. Aireku, P.C. Attah, I.I. Ijeh and C.E. Ugwu, 2012. Digging a little below the surface of the relationship between blood pressure and obesity: Dichotomous correlations in young-adult Nigerians. Continental J. Biomed. Sci., 6: 12-21.
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  39. Ejike, C.E.C.C. and L.U.S. Ezeanyika, 2012. A Telfairia occidentalis seeds-incorporated diet may be useful in inhibiting the induction of experimental andropause. Ann. Med. Health Sci. Res., 2: 41-45.
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  40. Ejike, C.E.C.C. and I.I. Ijeh, 2012. Hypertension and anxiety in young Nigerian adults: A study of an undergraduate population. J. Pharm. Allied Sci., 9: 1564-1573.
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  41. Ejike, C.E.C.C. and C.E. Ugwu, 2012. Association between blood pressure and urinary electrolytes in a population of non-urban-dwelling Nigerians. Niger. J. Clin. Pract., 15: 258-264.
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  42. Ejike, C.E.C.C. and I.I. Ijeh, 2012. Obesity in young-adult Nigerians: Variations in prevalence determined by anthropometry and bioelectrical impedance analysis, and the development of % body fat prediction equations. Int. Arch. Med., Vol. 5. 10.1186/1755-7682-5-22.
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  43. Udenigwe, C.C., C.E.C.C. Ejike, J.K. Quansah and M.O. Eze, 2011. Towards the management of hypertension: Modulation of the renin-angiotensin system by food protein hydrolysates and peptides. Biokemistri, 23: 106-117.
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  44. Okonkwo, F.O. and C.E.C.C. Ejike, 2011. Simulation of heavy metal contamination of fresh water bodies: Toxic effects in the catfish and its amelioration with co-contamination with glyphosate. J. Applied Sci. Environ. Manage., 15: 341-345.
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  45. Ijeh, I.I., O.W. Nwokohuru and C.E.C.C. Ejike, 2011. Oxidative stability of red palm oil from two oil palm varieties-Elaeis guineensis and Elaeis oleifera: Comparative effects of storage temperature and duration. Continental J. Food Sci. Technol., 5: 18-22.
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  46. Ijeh, I.I., K.K. Igwe and C.E.C.C. Ejike, 2011. Effect of leaf aqueous extracts of Vernonia amygdalina Del on contraction of mammary gland and uterus of guinea pig dams. Am. J. Trop. Med. Public Health, 1: 107-116.
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  47. Ijeh, I.I. and C.E.C.C. Ejike, 2011. Current perspectives on the medicinal potentials of Vernonia amygdalina Del. J. Med. Plant Res., 5: 1051-1061.
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  48. Ejike, C.E.C.C., 2011. Towards the prevention and management of prostatic diseases in Nigeria: A framework. Malaysian J. Med. Sci., 18: 65-70.
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  49. Ejike, C.E.C.C., 2011. Self-reported history of sexually transmitted infection and chronic prostatitis symptoms: A cross-sectional study of a Nigerian undergraduate population. Int. J. STD AIDS, 22: 91-94.
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  50. Ejike, C.E.C.C., 2011. Blood pressure to height ratios as simple, sensitive and specific diagnostic tools for adolescent (pre)hypertension in Nigeria. Ital. J. Pediatr., Vol. 37. 10.1186/1824-7288-37-30.
    CrossRef  |  Direct Link  |  

  51. Ejike, C.E.C.C. and O.C. Ezebuiro, 2011. Cardiometabolic risk factors’ prevalence in a population of geriatrics with elevated serum prostate specific antigen levels. Continental J. Med. Res., 5: 6-13.
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  52. Ejike, C.E.C.C. and L.U.S. Ezeanyika, 2011. Management of experimental benign prostatic hyperplasia in rats using a food-based therapy containing Telfairia occidentalis seeds. Afr. J. Trad. Complement. Altern. Med., 8: 398-404.
    CrossRef  |  

  53. Ejike, C.E.C.C. and L.U.S. Ezeanyika, 2011. Inhibition of the experimental induction of benign prostatic hyperplasia: A possible role for fluted pumpkin (Telfairia occidentalis Hook f.) seeds. Urol. Int., 87: 218-224.
    CrossRef  |  

  54. Ejike C.E.C.C., 2011. Lipid accumulation product and waist-to-height ratio are predictors of the metabolic syndrome in a Nigerian male geriatric population. J. Rural Trop. Public Health, 10: 101-105.
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  55. Ugwu, C.E., C.E.C.C. Ejike, E.O. Alumanah and L.U.S. Ezeanyika, 2010. Effect of dietary incorporation of Gongronema latifolium, Vernonia amygdalina and Telfairia occidentalis leaves at various levels, on the lipid profile of rats. Indian J. Anim. Nutr., 27: 303-308.
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  56. Ijeh, I.I., U. Okorie and C.E.C.C. Ejike, 2010. Obesity, metabolic syndrome and BMI-metabolic-risk sub-phenotypes: A study of an adult Nigerian population. J. Med. Med. Sci., 1: 254-260.
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  57. Ijeh, I.I., C.E.C.C. Ejike and U. Okorie, 2010. Serum lipid profile and lipid pro-atherogenic indices of a cohort of Nigerian adults with varying glycemic and blood pressure phenotypes. Int. J. Biol. Chem. Sci., 4: 2102-2112.

  58. Ijeh, I., C.E.C.C. Ejike, O.M. Nkwonta and B.C. Njoku, 2010. Effect of traditional processing techniques on the nutritional and phytochemical composition of African bread-fruit (Treculia africana) Seeds. J. Applied Sci. Environ. Manage., 14: 169-173.
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  59. Ezeigbo, I.I., C.E.C.C. Ejike, M.I. Ezeja and O. Eneh, 2010. Antioxidant and antidiarrhoeal activity of Manniophyton africanum leaf extract in mice. Continental J. Anim. Vet. Res., 2: 41-47.
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  60. Ejike, E.C.C.C., E.C. Ugwu and U.S.L. Ezeanyika, 2010. Physical growth and nutritional status of a cohort of semi-urban Nigerian adolescents. Pak. J. Nutr., 9: 392-397.
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  61. Ejike, C.E.C.C., P.C. Ugboaja and L.U.S. Ezeanyika, 2010. Dietary incorporation of boiled fluted pumpkin (Telfairia occidentalis Hook F.) seeds 1: Growth and toxicity in rats. Res. J. Biol. Sci., 5: 140-145.

  62. Ejike, C.E.C.C., O.O. Nwankwo and I.I. Ijeh, 2010. Consumption of coconut milk did not increase cardiovascular disease risk in mice. Int. J. Curr. Res., 6: 63-64.

  63. Ejike, C.E.C.C., C.E. Ugwu and L.U.S. Ezeanyika, 2010. Variations in the prevalence of point (pre)hypertension in a Nigerian school-going adolescent population living in a semi-urban and an urban area. BMC Pediatr., Vol. 10. 10.1186/1471-2431-10-13.
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  64. Ejike, C.E.C.C., A.H. Udensi and L.U.S. Ezeanyika, 2010. Dietary incorporation of boiled fluted pumpkin (Telfairia occidentalis Hook F.) seeds 2: Alterations in serum lipid profile and blood glucose concentration of rats. Res. J. Biol. Sci., 5: 146-149.
    CrossRef  |  Direct Link  |  

  65. Ejike, C.E.C.C. and L.U.S. Ezeanyika, 2010. Hormonal induction of benign prostatic hyperplasia in rats: Effects on serum macromolecular metabolism. Int. J. Curr. Res., 6: 65-67.

  66. Ejike, C.E.C.C. and C.E. Ugwu, 2010. The plateau effect of high blood pressure on the blood pressure versus body mass index curves of adult Nigerians. Niger. J. Biochem. Mol. Biol., 25: 72-77.
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  67. Ejike, C.E.C.C. and C.E. Ugwu, 2010. Hyperbolic relationship between blood pressure and body mass index in a Nigerian adolescent population. WMC Hypertension, Vol. 1. .
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  68. Ejike, C.E.C.C., C.E. Ugwu and L.U.S. Ezeanyika, 2009. Nutritional status, prevalence of some metabolic risk factors for cardiovascular disease and BMI-metabolic-risk sub-phenotypes in an adult Nigerian population. Biokemistri, 21: 17-24.
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  69. Ejike, C.E.C.C., C.E. Ugwu and L.U.S. Ezeanyika, 2009. Association between blood pressure and some other cardiovascular disease risk factors in a lean black population. Biokemistri, 21: 85-93.
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  70. Ejike, C.E.C.C. and N.T. Emmanuel, 2009. Cholesterol concentration in different parts of bovine meat sold in Nsukka, Nigeria: Implications for cardiovascular disease risk. Afr. J. Biochem. Res., 3: 95-97.

  71. Ejike, C.E.C.C. and L.U.S. Ezeanyika, 2009. Lifestyle changes in Nsukka metropolis in relation to prostate cancer and benign prostate hyperplasia. Niger. J. Biochem. Mol. Biol., 24: 55-59.
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  72. Ejike, C.E.C.C., E.O. Alumanah, L.U.S. Ezeanyika, A.A. Ngene and E.E. Ojefua, 2008. Antibiotics administration and its possible liver damage. Bio-Research, 6: 351-354.
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  73. Ejike, C.E.C.C., C.E. Ugwu, L.U.S. Ezeanyika and A.T. Olayemi, 2008. Blood pressure patterns in relation to geographic area of residence: A cross-sectional study of adolescents in Kogi state, Nigeria. BMC Public Health, Vol. 8. 10.1186/1471-2458-8-411.
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  74. Ejike, C.E.C.C. and L.U.S. Ezeanyika, 2008. Prevalence of chronic prostatitis symptoms in a randomly surveyed adult population of urban-community-dwelling Nigerian males. Int. J. Urol., 15: 340-343.
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  75. Ejike, C.E.C.C. and L.U.S. Ezeanyika, 2008. Metabolic syndrome in sub-Saharan Africa: Smaller twin of a region's prostatic diseases? Int. Urol. Nephrol., 40: 909-920.
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  76. Ejike, C.E.C.C. and L.U.S. Ezeanyika, 2007. Usefulness of the American urological association’s benign prostate hyperplasia symptom index in Nigeria: Validation using biochemical markers. J. Pharm. Allied Sci., 4: 461-466.
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  77. Ejike, C.E.C.C. and L.U.S. Ezeanyika, 2007. Prostatic acid phosphatase discriminates between chronic pelvic pain syndrome and lower urinary tract symptoms in elderly men. Bio-Research, 5: 247-250.
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  78. Ezeanyika, L.U.S., C.E.C.C. Ejike, O. Obidoa and S.O. Elom, 2006. Prostate disorders in an apparently normal Nigerian population 2: Relationship with some biochemical parameters. Biokemistri, 18: 133-139.
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  79. Ezeanyika, L.U.S., C.E.C.C. Ejike, O. Obidoa and S.O. Elom, 2006. Prostate disorders in an apparently normal Nigerian population 1: Prevalence. Biokemistri, 18: 127-132.
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