Dr. Ojochenemi Ejeh Yakubu

Reader
Federal University Wukari, Nigeria

Highest Degree
Ph.D. in Pharmacological Biochemistry from University of Nigeria, Nigeria

My URL
https://livedna.org/234.24862

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Biography

Ojochenemi Yakubu currently works in the Department of Biochemistry, Federal University Wukari. Their current project is 'Bioassay-guided fractionation, Purification of active ingredients and Determination antioxidant, hepatoprotective and antidiabetic activities of some indigenous medicinal plants.

Area of Interest:

Molecular Sciences
Pharmacological Biochemistry
Plant Extract
Antioxidants
Medical Biochemistry

Selected Publications

  1. Yakubu, O.E., V.O. Nwaneri-Ch, P.N. Ibuzo, R.E. Yohanna and O.M. Aledu et al., 2020. Ethanol extract of senna occidentalis leaves may ameliorate haematological damages induced by diethylnitrosamine in wistar rats. J. Plant Sci., 15: 33-38.
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  2. Yakubu, O.E., E. Ojogbane, V.O. Nwaneri-Chidozie, P.N. Ibuzo, Ale, E. M. and S.S. Awudu, 2020. Ameliorative effects of ethanol extract of ficus sur on diethylnitrosamine-induced hepatotoxicity in wistar rats. Am. J. Biochem. Mol. Bio., 10: 6-11.
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  3. Yakubu, O.E., E. Ojogbane, M.S. Abu, C.O. Shaibu and W.E. Ayegba, 2020. Haematinic effects of ethanol extract of Ficus sur leaves on diethylnitrosamine-induced toxicity in wistar rats. J. Pharmacol. Toxicol., 15: 16-21.
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  4. Yakubu, O.E., C. Imo, C. Shaibu, J. Akighir and D.S. Ameh, 2020. Effects of ethanolic leaf and stem-bark extracts of Adansonia digitata in alloxan-induced diabetic wistar rats. J. Pharmacol. Toxicol., 15: 1-7.
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  5. John, U.I., A.U. Hauwa, Y. Ojochenemi and U.K. Isaac, 2020. Isolation and characterization of chemical constituents, cytotoxicity, antibacterial and antioxidant activity of the isolates, crude extract from hornstedtia scyphifera var leaf. GSC Biol. Pharm. Sci., 10: 70-98.
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  6. Yakubu, O.E., R.H.N. Boyi, C. Shaibu, M.A. Abah and J. Akighir, 2019. Antioxidant parameters and GC-MS phytochemical analysis of Hymenocardia acida stem bark ethanolic extract. Trends Appl. Sci. Res., 14: 263-270.
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  7. Yakubu, O.E., K.A. Arowora, C.O. Shaibu and I. Osagie, 2019. Aflatoxins and their effects on the biological system. Eur. J. Biomed. Pharm. Sci., 6: 97-501.

  8. Otitoju, O., O.E. Yakubu, G.T.O. Otitoju and U.D. Okwara, 2019. A review of impact of recurrent bush burning on the climate change paradigm: The Nigerian experience. Int. J. Biol. Res., 4: 92-101.

  9. Imo, C., K.A. Arowora, C.S. Ezeonu, O.E. Yakubu, C.D. Nwokwu, N.C. Azubuike and Y.G. Sallah, 2019. Effects of ethanolic extracts of leaf, seed and fruit of Datura metel L. on kidney function of male albino rats. J. Traditional Complement. Med., 9: 271-277.
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  10. Imarenezor, E.P.K., N.P. Ofiri , O.E. Yakubu, S.T.C. Brown, F.U. Ebuara and S. Sani, 2019. CD4, CD8 T-lymphocytes and WBC profiles during pregnancy among HIV-seronegative women in Wukari, North East, Nigeria. FUW Trends Sci. Technol. J., 4 : 930-933.

  11. Arowora, K.A., O.J. Yakubu, C. Shaibu, T.J. Iornenge and K.C. Ugwuoke, 2019. Chemical composition of baobab leaves and fractionation of its ethanolic extract using column chromatography. Int. J. Sci. Res., 8: 812-821.
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  12. 9. Shaibu, C.O., O.E. Yakubu, V.E. Shaibu and O.A. Eze, 2019. Effect of crude cellulase from aspergillus fumigatus on extraction 0f shea fat. Adv. Biotech. Micro., Vol. 13. .
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  13. Yakubu, O.E., O. Otitoju, E.P.K. Imarenezor, V.S. Tatah and H. Bilyaminu, 2018. Fractionation and determination of antioxidant activities, of the leaves of Senna occidentalis ethanol extract. Open Sci. J. Pharm. Pharmacol., 6: 26-30.

  14. Umaru, I.J., F. Abadruddin, H. Aumaru, E.C. Stephen and O. Yakubu, 2018. APBVariation in the functional properties of barringtonia asiatica extract on selected pathogens. J. Pharmacol. Clin. Res., Vol. 6, No. 3 10.19080/JPCR.2018.06.555686.
    CrossRef  |  ASCI  |  Direct Link  |  

  15. Mamma, E., M.H. Mayel and O.E. Yakubu, 2018. Determination of glycemic indices of flour and starch components of selected maize and millet cereal varieties in diabetic rats. Innovative J. Med. Health Sci., 8: 198-202.
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  16. Kenneth1, I.E.P., B.S.T. Cockeye, Y.O. Ejeh, E.P. Ajakaiye, M.S. Peter and J.T. Ugye, 2018. Effectiveness of some selected toothpastes sold in wukari North East Nigeria on oral microflora. Am. J. Chem. Mater. Sci., 5: 20-27.

  17. Imo, C., O.E. Yakubu, N.G. Imo, I.S. Udegbunam, S.V. Tatah and O.J. Onukwugha, 2018. Proximate, mineral and phytochemical composition of Piper guineense seeds and leaves. J. Biol. Sci., 18: 329-337.
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  18. Imo, C., O.E. Yakubu, N.G. Imo, I.S. Udegbunam, S.V. Tatah and O.J. Onukwugha, 2018. Proximate, mineral and phytochemical composition of Piper guineense seeds and leaves. J. Biol. Sci., 10.3923/jbs.2018.
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  19. Imo, C., O.E. Yakubu, N.G. Imo, I.S. Udegbunam and O.J. Onukwugha, 2018. Chemical composition of Xylopia aethiopica fruits. Am. J. Physiol. Biochem. Pharmacol., 7: 48-53.
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  20. Imo, C., K.A. Arowora, C.S. Ezeonu, O.E. Yakubu, C.D. Nwokwu, N.C. Azubuike and Y.G. Sallah, 2018. Effects of ethanolic extracts of leaf, seed and fruit of Datura metel L. on kidney function of male albino rats. J. Tradit. Complement. Med., (In Press). 10.1016/j.jtcme.2017.09.001.
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  21. Imarenezor, E.P.K., S.T.C. Brown, O.E. Yakubu, P.A. Egwaikhide, S.P. Malu and T.U. Joseph, 2018. Efficiency of chickweed (Stellaria citrifolia) isolated from primary school pupils in Wukari North East Nigeria on oral microflora. FUW Trends Sci. Technol. J., 3: 615-618.

  22. Idoko, A., U.G. Emmanuel, O.E. Yakubu, P.O. Ugwudike and N.A. Patricia, 2018. Hepatocurative and gluco-stabilizing potentials of ethanol extract of stem bark of Flacourtia indica in aluminium chloride induced toxicity in Albino Wistar rats. Curr. Trends Biomed. Eng. Biosci., Vol. 17. .
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  23. Yakubu, O.E., O.F.C. Nwodo, C. Imo and H.A. Ogwoni, 2017. Spermatogenic and haematological effects of aqueous and ethanolic extracts of hymenocardia acida stem bark on aluminium-induced toxicity in male wistar rats. Insights Biomed., 2: 1-5.

  24. Yakubu, O.E., O. Otitoju and D. Okwara, 2017. Comparative hepatoprotective and haematological effects of the ethanol extracts of the leaves of Vitex doniana and Senna occidentalis in alloxan-induced diabetes in male wistar rats. J Anal. Pharm. Res., Vol. 4. 10.15406/japlr.2017.04.00099.
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  25. Yakubu, O.E., O. Olawale, K.A. Arowora and C. Imo, 2017. Biochemical changes in haematological and liver function parameters in intoxicated male albino rats treated with Hymenocardiaacida leaves ethanolic extract. Insights Biomed., 2: 10-14.
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  26. Yakubu, O.E., 2017. Amelioration of some indices of diabetic complications using Senna occidentalis leaf extract in alloxan-induced diabetes in rats. AASCIT J. Biosci., 3: 24-28.
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  27. Yakubu, O.E. and O.F.C. Nwodo, 2017. Changes in haematological parameters arising from alloxan-induced diabetes in rats treated withethanol extract Senna occidentalis leaves. Biochem. Mol. Biol., 2: 16-19.

  28. Yakubu, O.E, O. Otitoju and J. Onwuka, 2017. Gas chromatography-mass spectrometry (GC-MS) analysis of aqueous extract of Daniellia oliveri Stem Bark. Pharm. Acta, Vol.8. 10.4172/2153-2435.1000568.
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  29. Utubaku, A.B., O.E. Yakubu and D.U. Okwara, 2017. Comparative phytochemical analysis of fermented and unfermented seeds of Dialium giuneense. J. Tradit. Med. Clin. Natur., Vol. 6. .
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  30. Ojogbane, E., J.E. Olajide, O.E. Yakubu, D.A. Musa and P.I. Awodi, 2017. Phytochemical, anti-oxidant properties and lipid lowering effect of the aqueous extract of Dennettia tripetala fruits on Wistar rats. FUW Trend Sci. Technol. J., 2: 751-754.

  31. Yakubu, O.E., O.F.C. Nwodo, S.M.C. Udeh and M. Abdulrahman, 2016. The effects of aqueous and ethanolic extracts of Vitex doniana leaf on postprandial blood sugar concentration in wister rats. Int. J. Biochem. Res. Rev., 11: 1-7.
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  32. Yakubu, O.E., O.F.C. Nwodo, C. Imo, S.M.C. Udeh, M. Abdulrahaman and M.O. Ogri, 2016. Modulation of some biochemical complications arising from alloxan-induced diabetic conditions in rats treated with Senna occidentalis leaf extract. J. Applied Biol. Biotechnol., 4: 51-56.
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  33. Yakubu, O.E., O.F.C. Nwodo, C. Imo, M. Abdulrahaman and L.B. Uyeh, 2016. Effects of Vitex doniana leaf extract on aluminium-induced toxicity in male albino Wistar rats. J. Applied Biol. Biotechnol., 4: 37-40.
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  34. Yakubu, O.E., O.F.C. Nwodo and E.P.K. Imarenezor, 2016. Nephroprotective effects of leaves of Vitex doniana aqueous extract on streptozotocin-induced diabetic rats. FUW Trend Sci. Technol. J., 1: 288-291.

  35. Yakubu, O.E., E.P.K. Imarenezor and S.M.C. Udeh, 2016. Total antioxidant capacity, phenolic and flavonoids contents of partially purified aqueous extract of Vitex doniana leaves. FUW Trend Sci. Technol. J., 1: 221-224.
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  36. Yakubu, O.E., A.C. Obot and Y. Dawoye, 2016. Effects of aqueous extract of Hymenocardia acida leaves on aluminium chloride-induced toxicity in male albino rats. J. Anal. Pharm. Res., Vol. 3. 10.15406/japlr.2016.03.00049.
    CrossRef  |  Direct Link  |  

  37. Yakubu, O.E., 2016. Liver function status in male Wister rats treated with ethanol extract of the leaves of Nauclea latifolia owing to aluminum chloride-induced oxidative stress. J. Anal. Pharm. Res., Vol. 3. 10.15406/japlr.2016.03.00072.
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  38. Ojogbane, E.B., J.E. Olajide, O.E. Yakubu, A.D. Musa and P.I. Awodi, 2016. Proximate composition, anti-inflammatory and effects of aqueous extracts of Dennettiatripetala fruit on indomethacine and ethanol induced ulcer in albino rats. FUW Trends Sci. Technol. J., 1: 360-362.
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  39. Imarenezor, E.P.K., S.T.C. Brown, O.E. Yakubu and D.C. Soken, 2016. Survey of hepatitis b and c among students of federal university wukari, taraba state, Nigeria. Int. Res. J. Med. Med. Sci., 4: 31-37.
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  40. Imarenezor, E.P.K, O.P.G. Nmorsi, S.T.C. Brown, O.E. Yakubu and O.A. Abhadionmhen, 2016. Interleukin (il)-10 and tumour necrosis factor-alpha (Tnf –α) profiles of individuals with chistosoma haematobium infection in ewan community, edo state, Nigeria. FUW Trend Sci. Technol. J., 1: 24-25.
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  41. Yakubu, O.E. and O.F.C. Nwodo, 2015. Histopathological examination and changes in serum electrolytes in streptozotocin-induced diabetic rats owing to treatment with ethanol extract of Vitex doniana leaves. Int. J. Pharma Sci. Res., 6: 830-835.
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  42. Ojogbane., E., O.F.C. Nwodo, O.E. Yakubu and O. Abbah, 2015. Antioxidant capacity and phytochemical content of Cyphostemma glaucophilla aqueous leaf extract. Int. J. Pharma Sci. Res., 6: 512-516.
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  43. Yakubu, O.E., O.F.C. Nwodo, P.E. Joshua, M.N. Ugwu, A.D. Odu and F. Okwo, 2014. Fractionation and determination of total antioxidant capacity, total phenolic and total flavonoids contents of aqueous, ethanol and n-hexane extracts of Vitex doniana leaves. Afr. J. Biotechnol., 13: 693-698.
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  44. Ojogbane, E., O.F.C. Nwodo, J. Omale and O.E. Yakubu, 2014. Anti-microbial studies and the effect of the aqueous extract of Cyphostemma glaucophilla leaves on the oncentration of total plasma proteins and albumin in corn-meal induced kwashiorkor rats. Biolife, 2: 1008-1013.
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  45. Nwaneri-Chidozie, V.O., O.E. Yakubu, J.O. Sidikat, P. Phebe and K.C. Lele, 2014. Lipid profile status of streptozotocin-induced diabetic rats treated with ethanol, N-hexane and aqueous extracts of Vitex Doniana leaves. Res. J. Pharm., Biol. Chem. Sci., 5: 40-49.

  46. Atawodi, S.E.O., O.E. Yakubu, M.L. Liman and D.U. Iliemene, 2014. Effect of methanolic extract of Tetrapleura tetraptera (Schum and Thonn) Taub leaves on hyperglycemia and indices of diabetic complications in alloxan-induced diabetic rats. Asian Pac. J. Trop. Biomed., 4: 272-278.
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  47. Yakubu, O.E., E. Ojogbane, O.F.C. Nwodo, V.O. Nwaneri-Chidozie and M.N. Ugwu, 2013. Study of lipid profile and lipid peroxide in diabet es mellitus treated with Vitex doniana ethanol leaf extract. Eur. J. Exp. Bio., 3: 624-629.
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  48. Yakubu, O.E., E. Ojogbane, O.F.C. Nwodo, V.O. Nwaneri-Chidozie and K. Dasofunjo, 2013. Effect of Vitexdoniana ethanol leaf extract on renal function in diabetic rats. Euro. J. Exp. Bio., 3: 630-634.
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  49. Yakubu, O.E., E. Ojogbane, O.F.C. Nwodo, V.O. Nwaneri-Chidozie and K. Dasofunjo, 2013. Comparative antioxidant and hypoglycaemic effects of aqueous, ethanol and n-hexane extracts of leaf of Vitex doniana on streptozotocin-induced diabetes in albino rats. Afr. J. Biotech., 12: 5933-5940.
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  50. Ugwu, M.N., I.A. Umar, A.B. Utu-Baku, K. Dasofunjo, R.U. Ukpanukpong, O.E. Yakubu and A.O. Okafor, 2013. Antioxidant Status and Organ Function in Sreptozotocin- induced Diabetic Rats Treated with Aqueous, Methanolic and Petroleum Ether Extracts of Ocinum basilicum Leaf. J. Appl. Pharm. Sci., 3: 75-79.
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  51. Ugwu, M.N., I.A. Umar, A.B. Utu-Baku, K. Dasofunjo, R.U. Ukpanukpong, O.E. Yakubu and A.I. Okafor, 2013. Antioxidant status and organ function in streptozotocin-induced diabetic rats treated with aqueous, methanolic and petroleum ether extracts of Ocimum basilicum leaf. J. Applied Pharm. Sci., 3: S75-S79.
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  52. Dasofunjo, K., O.F.C. Nwodo, O.E. Yakubu, R. Ejoba and R.U. Ukpanukpong et al., 2013. Toxicological implication of ethanol leaf extract of Piliostigma thonningii on renal function indices of male wistar albino rats. Eur. J. Exp. Biol., 3: 652-655.
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  53. Dasofunjo, K., O.F.C. Nwodo, O.E. Yakubu, R. Ejoba and R.U. Ukpanukpong et al., 2013. Hepactoprotective effect of Piliostigma thonningii leaves on male wistar albino rats. Asian J. Plant Sci. Res., 3: 13-17.
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  54. Atawodi, S.E., O.E. Yakubu and I.A. Umar, 2013. Antioxidant and hepatoprotective effects of Parinari curatellifolia root. Int. J. Agric. Biol., 15: 523-528.

  55. Yakubu, O.E., S.E. Atawodi, E. Ojogbane and V.O. Nwaneri-Chidozie, 2012. Acute toxicity and antioxidant activity of Parinari curatellifollia root methanolic extract in carbon tetrachloride-induced toxicity in wistar rats. Int J. Basic Appl. Chem. Sci., 2: 82-89.
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  56. Yakubu, O.E., O.F. Nwodo, V.O. Nwaneri-Chidozie and E. Ojogbane, 2012. Amelioration of lipid peroxidation and oxidative stress in hepatocytes of streptozotocin-induced diabetic rats treated with aqueous extract of Vitex doniana leaves. Int. J. Basic Applied Chem. Sci., 2: 89-98.

  57. Atawodi, S.E., L.M.D. Yusufu, J.C. Atawodi, O. Asuko and O.E. Yakubu, 2011. Phenolic compounds and potential of Nigerian red palm oil (Elais guinensis). Int. J. Biol., Vol. 3. 10.5539/ijb.v3n2p153.
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