Dr. Isaac Uzoma Asuzu

Professor
Department of Veterinary Physiology & Pharmacology, University of Nigeria, Nsukka, Nigeria


Highest Degree
Ph.D. in Veterinary Pharmacology and Toxicology from University of Nigeria, Nigeria

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Area of Interest:

Animal and Veterinary Sciences
Veterinary Pharmacology
Phytochemical Screening
Toxicology
Veterinary Medicine

Selected Publications

  1. Madubuike, K.G., A.O. Anaga and I.U. Asuzu, 2021. Effect of methanol leaf extract of Pterocarpus santalidoides L’ Herit ex DC on the antioxidant and lipid profile of Wistar rats. Trop. J. Nat. Prod. Res., 5: 1295-1299.
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  2. Ihedioha, T.E., I.U. Asuzu and J.A. Nwanta, 2021. Retrospective survey of the patterns of prescription and request for vitamins, minerals and vitamin-mineral formulations for dogs in a veterinary hospital in Nigeria. Thai J. Vet. Med., 51: 605-611.
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  3. Ihedioha, T.E., I.U. Asuzu and J.A. Nwanta, 2021. Retrospective evaluation of the patterns of clinical use of anti-parasitic agents on animals presented for veterinary care at an animal hospital in Nigeria. Thai J. Vet. Med., 51: 75-83.
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  4. Ihedioha, T., I. Asuzu, A. Anaga and J. Ihedioha, 2021. Blood cellular, serum biochemical and organosomatic alterations in albino rats following sub-acute oral administration of varied doses of Pterocarpus santalinoides methanolic leaf extract. J. Complementary Med. Res., 12: 62-69.
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  5. Ihedioha, T., A.O. Anaga, I.U. Asuzu and J. Ihedioha, 2021. Comparative evaluation of the hepatoprotective activity of methanol leaf extracts of Pterocarpus santalinoides DC obtained by cold maceration and Soxhlet extraction techniques. Thai J. Pharm. Sci., 4: 442-450.
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  6. Attama, S.C., P.E. Aba, C.U. Asuzu and I.U. Asuzu, 2021. Comparative studies on the hypoglycemic and antioxidant activities of Vernonia amygdalina delile and Baccharoides tenoreana olive in alloxan-induced hyperglycemic rats. Clin. Phytosci., Vol. 7. 10.1186/s40816-021-00330-z.
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  7. Aba, P.E., J.I. Ihedioha and I.U. Asuzu, 2021. A review of the mechanisms of anti-cancer activities of some medicinal plants biochemical perspectives. J. Basic Clin. Physiol. Pharmacol., 10.1515/jbcpp-2021-0257.
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  8. Madubuike, K.G., A.O. Anaga and I.U. Asuzu, 2020. Chronic toxicity study of Pterocarpus santalinoides leaf extract in albino rats. Trop. J. Pharm. Res., 19: 2407-2413.
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  9. Madubuike, K.G., A.O. Anaga and I.U. Asuzu, 2020. Assessment of the antidiabetic potential of Pterocarpus santalinoides extract in alloxan-induced diabetic rats. Trop. J. Pharm. Res., 19: 2401-2406.
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  10. Ihedioha, T.E., A.E. Nnadozie, I.U. Asuzu, A.O. Anaga and J.I. Ihedioha, 2020. Effects of methanolic leaf extract of Pterocarpus santalinoides on the recovery from gentamicin-induced nephrotoxicity in albino rats. Comp. Clin. Pathol., 29: 1209-1217.
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  11. Uwagie-Ero, E.A., C.O. Nwaehujor, C.N. Abiazute, O.B. Ocheja, O.K. Ekeolu and I.U. Asuzu, 2018. D-3-0-methylchiroinositol (from Piliostigmathonningii) ameliorates Cadmium chloride (CdCl2)-induced toxicity in male reproduction. J. Appl. Sci. Environ. Manage., 22: 853-856.

  12. Udeh, N.E., A.O. Anaga and I.U. Asuzu, 2018. Protective effect of Gnetum africanum methanol leaf extract on pancreatic islet cells in rats. Comp. Clin. Pathol., 27: 649-654.
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  13. Udeh, N.E., A.O. Anaga and I.U. Asuzu, 2018. Fasting blood sugar and clinical biochemistry profiles of diabetic rats treated with methanol leaf extract of Gnetumafricanum Welw. Indian J. Tradit. Knowl., 17: 445-450.

  14. Udeh, N.E., A. Anaga and I.U. Asuzu, 2018. Effects of Gnetum africanum (Welw) methanol leaf extract on weight and haematological profile of wistar rats following chronic oral administration. Sokoto J. Vet. Sci., 16: 49-54.
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  15. Onoja, S.O., S.C. Udem, A.O. Anaga and I.U. Asuzu, 2018. Acute and chronic toxicity studies of hydromethanol leaf extract of Helianthus annuus Linn. in rats. Asian Pac. J. Trop. Med., 11: 534-539.
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  16. Aba, P.E. and I.U. Asuzu, 2018. Mechanisms of action of some bioactive antidiabetic principles from phytochemicals of medicinal plants: A review. Indian J. Nat. Prod. Resour., 9: 85-96.
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  17. Aba, P.E. and I.U. Asuzu, 2018. Glycosylated haemoglobin values of alloxan-induced diabetic rats treated with graded doses of Cussonia arborea extract. J. Applied Anim. Res., 46: 1478-1482.
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  18. Omoja, V.U., I.U. Asuzu and S.M. Anika, 2017. Haematological changes in albino wister rats exposed to sub-chronic administration of sub-lethal doses of Zamitraz®(12.5% amitraz). J. Applied Anim. Res., 45: 76-79.

  19. Onakpa, M.M., J.O. Ode, O.P. Ajagbonna and I.U. Asuzu, 2016. In vivo and in vitro antioxidant fffects of Icacina trichantha tuber extract. Niger. Vet. J., 37: 148-154.
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  20. Omoja, V.U., S.M. Anika and I.U. Asuzu, 2016. The effects of sub-chronic administration of sub-lethal doses of amitraz/xylene on selected reproductive parameters of male Wistar rats. Iran. J. Vet. Res., 17: 277-280.
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  21. Omoja, V.U., I.U. Asuzu and S.M. Anika, 2016. Assessment of the hepatic and renal effects of sub-chronic administration of sub-lethal doses of amitraz/xylene in albino Wistar rats. Comp. Clin. Pathol., 25: 203-209.
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  22. Nnaji, T. and R. Kene, 2016. Evaluation of the osteogenic potentials of the platelet-rich plasma and autologous cancellous bone grafts on ulna ostectomies of Nigerian local dogs. Comp. Clin. Pathol., 25: 225-230.

  23. Bosha, J.A., V.M. Ahur and I.U. Asuzu, 2016. Assessment of antidiabetic and antioxidant activities of Newbouldia leavis in alloxan-induced diabetes in albino rats. West Afr. J. Pharmacol. Drug Res., 31: 14-20.
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  24. Bosha, J.A., A.Y. Adenkola and I.U. Asuzu, 2016. Erythrocyte stability, membrane protective and haematological activities of Newbouldia laevis in alloxan–induced diabetic rats. Sokoto J. Vet. Sci., 14: 16-25.
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  25. Aba, P.E. and I.U. Asuzu, 2016. Effect of administration of methanol root bark extract of Cussonia arborea on serum lipid profile and oxidative biomarker parameters in alloxan-induced diabetic rats. Indian J. Anim. Res., 53: 1006-1013.
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  26. Aba, P.E. and I.U. Asuzu, 2016. Ameliorative Effects of Cussonia arborea methanol root bark extract on histomorphology of pancreas of alloxan-induced diabetic rats. Notulae Sci. Biol., 8: 277-280.
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  27. Aba, P.E. and I.U. Asuzu, 2016. 1H-proton NMR spectra of anti- hyperglycemic triterpenoid isolated from Cussoniaar borea. J. Nat. Prod., 9: 5-13.
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  28. Zhao, M., M.M. Onakpa, W.L. Chen, B.D. Santarsiero and S.M. Swanson et al., 2015. 17-Norpimaranes and (9βH)-17-norpimaranes from the tuber of Icacina trichantha. J. Nat. Prod., 78: 789-796.
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  29. Nwaehujor, C.O., R.I. Udegbunam and I.U. Asuzu, 2015. Analgesic, anti-inflammatory and anti-pyretic activities of D-3-O-methylchiroinositol isolated from stem bark of Piliostigma thonningii. Med. Chem. Res., 24: 4139-4145.
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  30. Ezeja, M.I., A.O. Anaga and I.U. Asuzu, 2015. Antidiabetic, antilipidemic, and antioxidant activities of Gouania longipetala methanol leaf extract in alloxan-induced diabetic rats. Pharm. Boil., 53: 605-614.
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  31. Bosha, J.A., A.A. Ottah and I.U. Asuzu, 2015. Bioassay-Guided Isolation and structural elucidation of antidiabetic principle of methanol leaf extract of newbouldia laevis (P. Beauv). J. Pharm. Pharmacol., 3: 516-526.
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  32. Aba, P.E. and I.U. Asuzu, 2015. Haematological profile of alloxan-induced diabetic rats treated with methanol root bark extract of Cussonia arborea. Int. Blood Res. Rev., 4: 1-10.
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  33. Aba, P.E. and I.U. Asuzu, 2015. Effects of administration of methanol root bark extract of Cussonia arborea on serum biochemical markers of liver damage and histo-morphology of liver of alloxan-induced diabetic rats. Br. J. Pharm. Res., 8: 1-10.
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  34. Aba, P.E. and I.U. Asuzu, 2015. Effects of administration of methanol root bark extract of Cussonia arborea on serum biochemical markers of kidney damage and renal histomorphology of alloxan-induced diabetic rats. J. Adv. Med. Pharm. Sci., 5: 1-9.

  35. Onakpa, M.M., M. Zhao, T. Godecke, W. Chen, C. Che, B.D. Santarsiero and I.U. Asuzu, 2014. Cytotoxic (9βH)‐Pimarane and (9βH)‐17‐norpimarane diterpenes from the tuber of Icacina trichantha. Chem. Biodivers., 11: 1914-1922.
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  36. Ode, O.J. and I.U. Asuzu, 2014. Luteolin isolate from the methanol extract identified as the single-carbon compound responsible for broad antiulcer activities of Cassia singueana leaves. IOSR J. Pharm., 4: 17-23.
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  37. Nwaehujor, C.O., O.V. Asuzu and IU. Asuzu, 2014. Membrane stability of red blood cells in diabetic mice treated with D-3-O-methylchiroinositol. Amer. J. Pharmac. Sci., 2: 24-26.

  38. Ezeja, M.I., A.O. Anaga and I.U. Asuzu, 2014. Acute and sub-chronic toxicity profile of methanol leaf extract of Gouania longipetala in rats. J. Ethnopharmacol., 151: 1155-1164.
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  39. Ezeja, M.I., A.O. Anaga and I.O. Asuzu, 2014. Effect of Gouania longipetala (Hemsl.) methanolic leaf extract on the kidney and hematology of alloxan-induced hyperglycemic Wistar rats. Comp. Clin. Pathol., 23: 1697-1702.
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  40. Aba, P.E., C.U. Nwaigwe, F.O. Okwuagwu, S.C. Udem and I.U. Asuzu, 2014. Effect of aqueous extract of Hibiscus sabdariffa on some biochemical parameters in alloxan-induced diabetic rats. Comp. Clin. Pathol., 23: 1675-1680.
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  41. Udegbunam, R.I., I.U. Asuzu, R.O.C. Kene and S.O. Udegbunam, 2013. Evaluation of local anaesthetic efficacy of the crude extract of Sterculia tragacantha using West African Dwarf Goats. Sokoto J. Vet. Sci., 11: 13-21.
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  42. Udegbunam, R.I., I.U. Asuzu, R.O. Kene, C.T. Oyiga, S.O. Udegbunam and C.C. Nwaehujor, 2013. Anti-inflammatory and anti-oxidant effects of Sterculia tragacantha fractions in mice. Afr. J. Biotechnol., 12: 592-597.
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  43. Onakpa, M.M., T. Godecke, M. Zhao, B.D. Santarsiero, I.U. Asuzu and C.T. Che, 2013. 9β-pimarane diterpenes from the tuber of icacina trichantha. Plant Med., Vol. 79. 10.1055/s-0033-1348684.
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  44. Ogbu, S.O., K.K. Agwu and I.U. Asuzu, 2013. Gongronema latifolium delays gastric emptying of semi-solid meals in dogs. Afr. J. Tradit. Comp. Altern. Med., 10: 325-331.
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  45. Ogbu, S.A., K.K. Agwu and I.U. Asuzu, 2013. Effect of Gongronema latifolium on gastric emptying in healthy dogs. World J. Gastroenterol., 19: 897-902.
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  46. Asuzu, I.U. and C.O. Nwaehujor, 2013. The Anti-diabetic, hypolipidemic and anti-oxidant activities of D-3-O-methylchiroinositol in alloxan-induced diabetic rats. Hygeia J. Drugs Med., 5: 27-33.
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  47. Adiele, R.C., B.B. Fakae and I.U. Isuzu, 2013. Anthelmintic activity of Securidaca longepedunculata (Family: Polygalaceae) root extract in mice, in vitro and in vivo. Asian Pac. J. Trop. Med., 6: 841-846.
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  48. . Ihedioha, T.E., V.U. Omoja and I.U. Asuzu, 2013. Acute toxicity, phytochemical constituents and in vitro anti-oxidant activity of crude methanolic stem bark extract of Cassia sieberiana dc. J. Vet. Applied Sci., 3: 1-9.

  49. Udegbunam, R.I., I.U. Asuzu, R.O.C. Kene, S.O. Udegbunam and C.O. Nwaehujor, 2012. Local anesthetic and tissue effects of the leaf extract and fractions of Sterculia tragacantha Lindl. J. Pharmacol. Toxicol., 7: 192-198.
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  50. Odo, R.I., I.U. Asuzu and P.E. Aba, 2012. The antidiabetic activities of the methanolic root bark extract of Afzelia africana in alloxan-induced diabetic mice. J. Complem. Integ. Med., 9: 1553-3840.
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  51. Nweze, N.E., B.M. Anene, I.U. Asuzu and W.S. Ezema, 2012. Subacute toxicity study of the methanolic seed extract of Buchholzia coriacea (Capparaceae) in rats. Comp. Clin. Pathol., 21: 967-974.
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  52. Madubunyi, I.I., S.O. Onoja and I.U. Asuzu, 2012. In vitro antioxidant and in vivo antidiabetic potential of the methanol extract of Ficus glumosa Del (Moraceae) stem bark in alloxan-induced diabetic mice. Comp. Clin. Pathol., 21: 389-394.
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  53. Ezeigbo, I.I. and I.U. Asuzu, 2012. Anti-diabetic activities of the methanol leaf extracts of Hymenocardia acida (Tul.) in alloxan-induced diabetic rats. Afr. J. Tradit. Complem. Altern. Med., 9: 204-209.

  54. Aba, P.E., I.U. Asuzu and R.I. Odo, 2012. Antihyperglycaemic and antioxidant potentials of Cussonia arborea in alloxan-induced diabetic rats. J. Comp. Clin. Pathol., 23: 451-458.
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  55. Udegbunam, R.I., I.U. Asuzu, R.O.C. Kene, S.O. Udegbunam and C. Nwaehujor, 2011. Antinociceptive, anti-inflammatory and anti-oxidant effects of the methanol leaf extract of Sterculia tragacantha Lindl. J. Pharmacol. Toxicol., 6: 516-524.
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  56. Omoja, V.U., A.O. Anaga, I.R. Obidike, P.U. Umeakuana and L.I. Mhomga et al., 2011. The effects of combination of methanolic leaf extract of Azadirachta indica and diminazene diaceturate in the treatment of experimental Trypanosoma brucei brucei infection in rats. Asia Pac. J. Trop. Med. Sci., 4: 337-341.
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  57. Ode, O.J., I.U. Asuzu and I.E.Ajayi, 2011. Bioassay-guided fractionation of the crude methanol extract of cassia singueana leaves. J. Adv. Sci. Res., 2: 81-86.
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  58. Nweze, N.E., B.M. Anene and I.U. Asuzu, 2011. Investigation of the anti-trypanosomal activity of Buchholzia coriacea seed extract against a field strain of Trypanosoma congolense. Afr. J. Tradit. Comp. Altern. Med., 8: 175-180.

  59. Nweze, N.E., B.M. Anene and I.U. Asuzu, 2011. In vitro anti-trypanosomal activities of crude extracts, β-sitosterol and α-sulphur from Buchholzia coriacea seed. Afr. J. Biotechnol., 10: 15626-15632.
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  60. Nwaehujor,C., I.I. Ezeigbo, N.E. Ude, M.I. Ezeja and I.U. Asuzu, 2011. Anti-inflammatory and antioxidant activities of the methanolic extracts of the stalk of Parkia biglobosa (JACQ.) BENTH. Hygeia J. Drugs Med., 3: 34-40.

  61. Bosha, J.A. and I.U. Asuzu, 2011. Some aspects of the pharmacology of the methanolic extract of Prosopis Africana (Fruit)(Guill and Peer) Taub. Trop. Vet., 29: 1-11.
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  62. Anaga, A.O. and I.U. Asuzu, 2011. Glucose uptake-enhancing activity of the ethyl acetate extract of Dennettia tripetala in 3T3-L1 adipocytes. J. Compl. Integ. Med., 8: 1-14.
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  63. Igboeli, O.O. and I.U. Asuzu, 2010. Sub-chronic toxicity of Senilia senilis hepatopancreas in albino Wistar mice. Bull. Environ. Contam. Toxicol., 84: 657-661.
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  64. Ezeigbo, I.I and I.U. Asuzu, 2010. Preliminary evaluation of the antihyperglycaemic properties of medicinal plants in Nsukka Area, Enugu State, Nigeria. Int. J. Curr. Res., 5: 006-008.

  65. Bosha, J.A., I.U. Asuzu and P.A. Onyeyili, 2010. Pharmacological effects of a fraction of the methanolic extract of prosopis africana fruit (Guill and Perr) Taub. Niger. Vet. J., 31: 235-241.
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  66. Adika, O.A., I.I. Madubunyi and I.U. Asuzu, 2010. Antidiabetic and antioxidant effects of the methanol extract of Bridelia micrantha (Hochst) Baill. (Euphorbiaceae) leaves on alloxan-induced diabetic albino mice. Comp. Clin. Pathol., .
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  67. Nweze, N.E., N.E. Fakae and I.U. Asuzu, 2009. Trypanocidal activity of the ethanolic extract of Buchholzia coriacea seed. Niger. Vet. J., 29: 1-6.
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  68. Igboeli, O.O. and I.U. Asuzu, 2009. Diarrhetic type shellfish poisoning in Nigeria. Bull. Environ. Contam. Toxicol., 84: 15-18.

  69. Anaga, A.O. and I.U. Asuzu, 2009. Antihyperglycaemic properties of the ethyl acetate extract of Dennetia tripetala in diabetic rats. J. Complem. Integ. Med., 7: 1-11.

  70. Ode, O.J. and I.U. Asuzu, 2006. The anti-snake venom activities of the methanolic extract of the bulb of Crinum jagus (Amaryllidaceae). Toxicon, 48: 331-342.
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  71. Nweze, N.E. and I.U. Asuzu, 2006. The anthelmintic effects of Buchholzia coriacea seed. Niger. Vet. J., 27: 60-65.

  72. Anaga, A.O., S.V.O. Shoyinka and I.U. Asuzu, 2006. Toxic effects of Dennettia tripetala. root extract. Pharm. Boil., 44: 451-461.
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  73. Asuzu, I.U., 2005. A Review on Croton penduliflorus seed extract. Recent Progress in Medicinal Plants. Stadium Press LLC, USA, Pages: 32.

  74. Anaga, A.O., C.J. Njoku, E.S. Ekejiuba, M.N. Esiaka and I.U. Asuzu, 2004. Investigations of the methanolic leaf extract of Costus afer. Ker for pharmacological activities in vitro and in vivo. Phytomedicine, 11: 242-248.
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  75. Asuzu, I.U. and A.L. Harvey, 2003. The antisnake venom activities of Parkia biglobosa (Mimosaceae) stem bark extract. Toxicon, 42: 763-768.
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  76. Uchendu, C.N., T.N. Kamalu and I.U. Asuzu, 2000. A preliminary evaluation of antifertility activity of a triterpenoid glycoside (DSS) from Dalbergia saxatilis in female Wistar rats. Pharmacol. Res., 41: 521-525.
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  77. Asuzu, I.U., S. Sossa and R.D. Loggia, 1999. The anti-inflammatory activity of the extracts of Icacina trichantha tuber. Phytomedicine, 6: 267-272.

  78. Asuzu, I.U and A.L. Harvey, 1999. The anti-snake venom activity of UNST4, an extract from the leaves of a Nigerian plant. Toxicon, 37: 291-296.

  79. Njoku, C.J and I.U. Asuzu, 1998. The anthelmintic effects of the leaf extract of Ocimum gratissimum (L.). Phytomedicine, 5: 485-488.
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  80. Asuzu, I.U., S. Ezejiofor and C.J. Nioku, 1998. The pharmacological activities of Olax viridis root bark extract on central nervous system. Fitoterapia, 69: 260-264.

  81. Asuzu, I.U. and C.U. Aforonwa, 1998. The pharmacological effects of Icacina trichantha leaf methanol extract. J. Herbs Spices Med. Plant, 6: 49-56.
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  82. Asuzu, I.U. and A.L. Harvey, 1998. Screening of some Nigerian medicinal plants for antisnake venom activity. Naunyn-Schmiedebergs Arch. Pharmacol., 358: 5169-5169.

  83. Njoku, C.J., L. Zeng, I.U. Asuzu, N.H. Oberlies and J.L. Mclaughlin, 1997. Oleanolic acid, a bioactive component of the leaves of Ocimum gratissimum (lamiaceae). Pharma. Biol., 35: 134-137.
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  84. Njoku, C.J., D.C. Hopp, F. Alali, I.U. Asuzu and J.L. McLaughlin, 1997. Dihydroguaiaretic acid: A bioactive component of the stem bark of pycnanthus angolensis. Planta Med., 63: 580-581.

  85. Asuzu, I.U. and R.I. Adimorah, 1997. The anti-inflammatory activity of extracts from the root of Combretum dolichopetalum. Phytomedicine, 4: 331-357.

  86. Asuzu, I.U. and O.K. Egwu, 1997. Search for the centrally active component of Icacina trichantha tuber. Phytomedicine, 4: 335-357.

  87. Udem, S.C., I. Madubunyi, I.U. Asuzu and S.M. Anika, 1996. The trypanocidal action of the root extract of Combretum dolichopetalum. Fitoterapia, 67: 31-37.

  88. Njoku, C.J., O.E. Okeyode, I.U. Asuzu and B.B. Fakae, 1996. The anthelmintic activities of Pleiocarpa bicarpellata leaf aqueous extract. Fitoterapia, 67: 339-343.

  89. Madubunyi, I.I. and I.U. Asuzu, 1996. Pharmacological screening of Anthocleista nobilis root bark. Int. J. Pharmacog., 34: 28-33.
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  90. Asuzu, I.U. and S.N. Shetty, 1996. Acute aflatoxicosis in broiler chicken in Nsukka, Nigeria. Trop. Vet., 4: 79-80.

  91. Asuzu, I.U. and J.C. Njoku, 1996. The anthelmintic effect of Alstonia boonei bark and Nauclea latifolia leaf aqueous extracts on Trychostrongylus infective larvae. Fitoterapia, 67: 220-222.
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  92. Asuzu, I.U. and I.I. Abubaker, 1996. The emetic antihepatotoxic and antinephrotoxic effects of an extract from Icacina trichantha. J. Herbs Spices Med. Plants, 3: 9-20.
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  93. Asuzu, I.U. and A.O. Anaga, 1996. The antiulcer effect of the methanolic extract of Triclisia subcordata leaves in rats. J. Herbs, Spices Med. Plants, 3: 45-53.
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  94. Odika, I.E., I.U. Asuzu and S.M. Anika, 1995. The effects of hyperosmolar agents lithium chloride and sucrose on the brain concentration of diminazene aceturate in rats. Acta Trop., 60: 119-125.
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  95. Odika, I.E., I.U. Asuzu and S.M. Anika, 1995. The chemotherapeutic efficacy of diminazene aceturate and lithium chloride against relapse infection of Trypanosoma brucei brucei in rats. Trop. Med. Parasitol., 46: 99-102.
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  96. Asuzu, I.U., U.O. Okoro and A.O. Anaga, 1995. The effects of the methanolic leaf extract of Triclisia subcordata Oliv. on smooth muscles. J. Herbs, Spices Med. Plants, 2: 11-18.
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  97. Asuzu, I.U. and I.I. Abubakar, 1995. The effects of Icacina trichantha tuber extract on the nervous system. Phytother. Res., 9: 21-25.
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  98. Anaga, A.O. and I.U. Asuzu, 1995. The methanolic extract of Triclisia subcordata leaves on the nervous system of mice. J. Herbs Spices Med. Plants, 3: 45-53.

  99. Asuzu, I.U. and O.U. Onu, 1994. The evaluation of the ethanolic bark extract of Piliostigma thonningii as an anthelmintic in Ascaridia galli infected chickens. Fitoterapia, 64: 291-297.

  100. Asuzu, I.U., A.O. Nwele and A.O. Anaga, 1993. The pharmacological activities of the bark methanolic extract of Berlinia grandiflora. Fitoterapia-Milano, 64: 529-534.

  101. Asuzu, I.U. and O.U. Onu, 1993. The in vitro acute toxicity of Piliostigma thonningii bark extract of Berlinia grandiflora. Fitoterapia., 60: 524-528.

  102. Asuzu, I.U. and J.C. Njoku, 1992. The pharmacological properties of the ethanolic root extract of Combretum dolichopetalum. Phytother. Res., 6: 125-128.
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  103. Shetty, S.N., I.U. Asuzu, S.M. Anika and D.N. Ezeasor, 1991. Drug metabolising enzyme activity in rapidly prepared liver microsomes of West African Dwarf (WAD) goats. Indian Vet. J., 68: 23-27.

  104. Asuzu, I.U. and A.O. Anaga, 1991. Pharmacological screening of the aqueous extract of Alstonia boonei stem bark. Fitoterapia, 63: 411-417.

  105. Asuzu, J.U., S.W. Shelty and S.M. Anika, 1990. Effects of chronic oral administration in mice of the gut-stimulating crystals of Croton penduliflorus seed oil. J. Ethnopharmacol., 30: 135-143.
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  106. Asuzu, I.U. and E.E. Ugwueze, 1990. Screening of Icacina trichantha extracts for pharmacological activity. J. Ethnopharmacol., 28: 151-156.
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  107. Asuzu, I. U. and C.N. Chineme, 1990. Effects of Morinda lucida leaf extract on Trypanosoma brucei brucei infection in mice. J. Ethnopharmacol., 30: 307-313.
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  108. Shetty, S.N. and I.U. Asuzu, 1989. Some pharmacokinetic aspects of sulphacetamide, sulphadimidine and sulphanilamide in West-African Dwarf (WAD) goats. Indian J. Pharmacol., 21: 73-80.
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  109. Shetty, S.N. and I.U. Asuzu, 1989. Distribution and excretion of sulfacetamide, sulfadimidine and sulfanilamide in West-African dwarf goats. Indian Vet. J., 66: 928-932.

  110. Asuzu, I.U., S.N. Shetty and S.M. Anika, 1989. The toxic effects of a chronic administration of the gut-stimulating principle in Croton penduliflorus Hutch. Seeds in mice. Drug Chem. Toxicol., 12: 85-93.
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  111. Asuzu, I.U., S.N. Shetty and S.M. Anika, 1989. Effects of the gut-stimulating principle in Croton penduliflorus seed oil on the central nervous system. J. Ethnopharmacol., 26: 111-119.
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  112. Asuzu, I.U. and O.U. Onu, 1989. Screening of the ethanolic root extract of Combretum dolichopetalum (Family: Combretaceae) for anti-ulcer activity. Int. J. Crude Drug Res., 28: 27-32.

  113. Asuzu, I.U. and M.O. Ugwuja, 1989. A preliminary study of the biological activities of the bark extract of Piliostigma thonningii (Schum) in mice. Phytother. Res., 3: 209-211.
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  114. Okoye, J.A., I.U. Asuzu and H.A. Gugnani, 1988. Two cases of aflatoxicosis characterised by paralysis and lameness in broilers. Avian pathol., 17: 731-734.

  115. Asuzu, I.U., S.N. Shetty and S.M. Anika, 1988. Pharmacologic actions of the gut active principles in Croton penduliflorus Hutch. Seed oil on smooth and skeletal muscles and on blood pressure. Phytother. Res., 2: 170-174.

  116. Asuzu, I.U., S.N. Shetty and S.M. Anika, 1988. Investigations of cytoprotective effects of the gut stimulating principle in Croton penduliflorus Hutch. Seed oil. Phytother. Res., 3: 33-35.

  117. Asuzu, I.U., A.I. Gray and P.G. Waterman, 1988. The extraction, isolation and identification of the purgative component of Croton penduliflorus seed oil. J. Ethnopharmacol., 23: 267-271.
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  118. Asuzu, I.U. and S.N. Shetty, 1988. Whole blood and plasma cholinesterase activity in West African Dwarf goats. Trop. Vet., 6: 39-42.

  119. Asuzu, I.U. and C.N. Chineme, 1988. Acute toxicity and gastrointestinal irritant effect of Croton penduliflorus seed oil in mice. Phytother. Res., 2: 46-50.
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  120. Asuzu, I. U., S.N. Shetty and O. Obidoa, 1988. The interaction of aflatoxin B1 with vitamin K, phenylbutazone and sulfamethoxine in rats. Biochem. Med. Metabolic Biol., 39: 158-167.
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  121. Shetty, S.N., I.U. Asuzu and S.M. Anika, 1987. Aflatoxin contamination of animal feedstuff in Anambra State. Trop. Vet., 5: 21-24.

  122. Shetty, S.N. and I.U. Asuzu, 1987. Whole blood and plasma cholinesterase activity of seven species of domestic animals in Nigeria. Indian J. An. Sci., 57: 166-170.

  123. Onyekweodiri, E.C., I.U. Asuzu and S.N. Shetty, 1987. Natural aflatoxicosis in Alsatian dogs in Nigeria. Bull. Anim. Hlth. Prod. Africa, 36: 380-384.

  124. Asuzu, I.U., 1987. The effect of Croton penduliflorus hutch. seed oil on gastric emptying in rats. Int. J. Crude Drug Res., 25: 77-80.
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  125. Asuzu, I.U., 1987. Biological assay of Croton penduliflorus Hutch. seed oil in mice. Int. J. Crude Drug Res., 25: 44-48.
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  126. Anika, S.M., S.N. Shetty, I.U. Asuzu and A.B. Chime, 1987. Effects of some trypanocides and anti-inflammatory agents in experimental Trypanosoma brucei infection in mice. Zariya Vet., 2: 9-15.

  127. Asuzu, I.U., 1986. Pharmacological evaluation of the folklore use of Sphenostylis stenocarpa. J. Ethnopharmacol., 16: 263-267.
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  128. Asuzu, I.U. and A. Undie, 1986. Some observations on the toxic effects of the seed extract of Sphenostylis stenocarpa (Hochst ex A. Rich) Harms. on intestinal muscle. Plant Foods Human Nutr., 36: 3-9.
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  129. Asuzu, I.U., S.N. Shetty and S.M. Anika, 1985. Investigations on Croton penduliflorus Hutch.: IV. Action of the seed oil on isolated smooth muscles. Int. J. Crude Drug Res., 23: 131-135.
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  130. Asuzu, I.U., S.M. Anika and S.N. Shetty, 1985. Investigations on Croton penduliflorus Hutch: V. Action of the seed oil on isolated skeletal muscles. Int. J. Crude Drug Res., 23: 185-189.

  131. Asuzu, I.U. and J.A. Orajaka, 1984. Organophosphate poisoning in cattle at the University farm of the University of Nigeria Nsukka. Nig. Vet. J., 13: 43-49.

  132. Shetty, S.N., S.M. Anika and U.I. Asuzu, 1983. Investigations on Croton penduliflorus hutch.: i. observations on pharmacognostic, physicochemical and pharmacological characteristics. Int. J. Crude Drug Res., 21: 49-58.
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