Dr. Afonne, Onyenmechi Johnson
LecturerNnamdi Azikiwe University, Nigeria
Highest Degree
Ph.D. in Pharmacology from Nnamdi Azikiwe University, Awka, Nigeria
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Area of Interest:
Selected Publications
- Oluboyo, A.O., C.C. Onyenekwe, O.J. Afonne, B.O. Oluboyo, D.A. Orji and M. Nwankwo, 2010. Some biochemical parameters in pre and post menopausal women in Nnewi, Nigeria. Afr. J. Med. Sci., 3: 11-16.
- Afonne, O., O. Orisakwe and I. Onyiaorah, 2010. Reproductive effects of two crude oils in male guinea pig. Abstr. Toxicol. Lett., 196S: S185-S186.
CrossRef | - Oluboyo, A.O., O.J. Afonne, B.O. Oluboyo, A.C. Okeke, R.C. Chukwuanukwu and T.O. Chukwuanukwu, 2009. Pattern of lipid profiles in HIV seropositive subjects on antiretroviral therapy. J. Adv. Med. Pharmaceut. Sci., 3: 40-42.
- Orisakwe, O.E., E. Nwachukwu, H.B. Osadolor, O.J. Afonne and C.E. Okocha, 2007. Liver and kidney function tests amongst paint factory workers in Nkpor, Nigeria. Toxicol. Ind. Health, 23: 161-165.
CrossRef | - Chiroma, H.D., G.T. Ayinla, O.E. Orish, O.O. Emmanuel and A.A. Jigam et al., 2007. Seasonal nitrate content of stream water, soil and some Foodstuffs samples in Abuja municipal area of Federal Capital Territory,Nigeria. J. Health Sci., 53: 359-364.
Direct Link | - Orisakwe, O.E., I.O. Igwilo, J.O. Afonne, J.U. Maduabuchi and J.C. Nduka, 2006. Heavy metal hazards of sachet water in Nigeria. J. Arch. Environ. Occup. Health, 61: 209 -213.
CrossRef | PubMed | Direct Link | - Igwilo, I.O., J.O. Afonne, U.J. Maduabuchi and O.E. Orisakwe, 2006. Toxicological study of the Anam River in Otuocha, Anambra State, Nigeria. J. Arch. Environ. Occup. Health, 61: 205-208.
CrossRef | PubMed | Direct Link | - Orisakwe, O.E., D.D. Akumka, A.A. Njan, O.J. Afonne and O.O. Okechi, 2005. Hepatotoxic and haematologic effects of Nigerian bonny light crude oil in male albino rats. Toxicol. Environ. Chem., 87: 215-221.
CrossRef | Direct Link | - Asomugha, R., O.E. Orisakwe, O.J. Afonne, E. Obi, J.C. Nduka and C.E. Dioka, 2005. Impact of effluents from cable manufacturing plant on food, water and soil qualities in nnewi, Nigeria. Pak. J. Biol. Sci., 8: 744-747.
CrossRef | Direct Link | - Ugwoke, C.C., E.D. Nwobodo, P. Unekwe, S.T. Chukwuma, M.A.C. Odike and O.J. Afonne, 2004. Fuel vapour disrupts the histoarchitecture of reproductive organs in albino rats (Wistar). J. Sci. Indust. Stud., 2: 72-74.
- Orisakwe, O.E., R. Asomugha, O.J. Afonne, C.N. Anisi, E. Obi and C.E. Dioka, 2004. Impact of effluents from a car battery manufacturing plant in Nigeria on water, soil and food qualities. Arch Environ. Health, 59: 31-36.
CrossRef | Direct Link | - Orisakwe, O.E., D.D. Akumka, A.A. Njan and O.J. Afonne, 2004. Testicular toxicity of Nigerian bonny light crude oil in male albino rats. Reprod. Toxicol., 18: 439-442.
PubMed | - Orisakwe, O.E., D.C. Husaini and O.J. Afonne, 2004. Testicular effects of sub-chronic administration of Hibiscus sabdariffa calyx aqueous extract in rats. Reprod. Toxicol., 18: 295-298.
CrossRef | PubMed | Direct Link | - Orisakwe, O.E., O.J. Afonne, M.A. Chude, E. Obi and C.E. Dioka, 2003. Sub-chronic toxicity studies of the aqueous extract of Boerhavia diffusa leaves. J. Health Sci., 49: 444-447.
Direct Link | - Ofoefule, S.I., C.E. Obodo, O.E. Orisakwe, O.J. Afonne and N.A. Ilondu et al., 2002. Salivary and urinary excretion and plasma-saliva concentration ratio of isoniazid (INH) in the presence of co-administered ciprofloxacin. Am. J. Ther., 9: 15-18.
Direct Link | - Dioka, C., O.E. Orisakwe, O.J. Afonne, P.U. Agbasi, D.D. Akumka, C.J. Okonkwo and N. Ilondu, 2002. Investigation into the haematologic and hepatic effects of rinbacin in rats. J. Health Sci., 48: 393-398.
Direct Link | - Afonne, O.J., O.E. Orisakwe, S.I. Ofoefule, S. Tsalha, E. Obi, N.A. Ilondu and O. Okorie, 2002. Saline cathartics and adsorptive capacity of activated charcoal for doxycycline. Acta Poloniae Pharmaceutica-Drug Res., 59: 177-179.
PubMed | Direct Link | - Afonne, O.J., O.E. Orisakwe, E. Obi, C.E. Dioka and G.I. Ndubuka, 2002. Nephrotoxic actions of low-dose mercury in mice: Protection by zinc. Arch. Environ. Health., 57: 98 -102.
PubMed | - Afonne, O.J., O.E. Orisakwe, C.E. Dioka, E. Obi, T. Ezejiofor, L. Asomugha and U. Ukoha, 2002. Effects of rinbacin on rat kidney. Biol. Pharm. Bull., 28: 1022-1025.
- Afonne, O.J., O.E. Orisakwa, O.A. Ekanem and D.D. Akumka, 2002. Zinc protects chromium-induced testicular injury in mice. Indian J. Pharmacol., 34: 26-31.
Direct Link | - Orisakwe, O.E., O.J. Afonne, E. Nwobodo, L. Asomugha and C.E. Dioka, 2001. Low-dose mercury induces testicular damage protected by zinc in mice. Eur. J. Obstet. Gynecol. Reprod. Biol., 95: 92-96.
CrossRef | PubMed | - Ofoefule, S.I., C.E. Obodo, O.E. Orisakwe, N.A. Ilondu and O.J. Afonne et al., 2001. Some plasma pharmacokinetic parameters of isoniazid (INH) in the presence of a fluoroquinolone antibacterial agent. Am. J. Ther., 8: 243-246.
PubMed | - Chude, M.A., O.E. Orisakwe, O.J. Afonne, K.S. Gamaniel, O.H. Vongtau and E. Obi, 2001. Hypoglycaemic effect of the aqueous extract of Boerhavia diffusa leaves. Indian J. Pharm., 33: 215-216.
Direct Link | - Agbasi, P.U., O.E. Orisakwe, E. Obi, S.I. Ofoefule, N.A. Ilondu and O.J. Afonne, 2001. Effect of sulphate cathartics on the adsorption of rifampicin to activated charcoal. Indian J. Pharmac. Sci., 63: 328-330.
Direct Link | - Orisakwe, O.E., N.A. Ilondu, O.J. Afonne, S.I. Ofoefule and C.N. Orish, 2000. Acceleration of body clearance of diethylcarbamazine by oral activated charcoal. Pharm. Res., 42: 167-170.
PubMed | - Orisakwe, O.E., K.C. Chilaka, O.J. Afonne, E. Obi and N. Ilondu, 2000. Evaluation of the developmental toxicity of amlodipine besylate in mice. J. Health Sci., 46: 42-45.
Direct Link | - Orisakwe, O.E., D.D. Akumka, O.J. Afonne and K.S. Gamaniel, 2000. Investigation into the pharmacological basis for some of the folkoric uses of bonny light crude oil in Nigeria. Indian J. Pharm., 32: 231-234.
Direct Link | - Obi, E., J.K. Emeh, O.E. Orisakwe, O.J. Afonne, N.A. Ilondu and P.U. Agbasi, 2000. Investigation of the biochemical evidence for the antiulcerogenic activities of Synclisia scabrida. Indian J. Phamcol., 32: 381-383.
Direct Link | - Ilondu, N., O.E. Orisakwe, S.I. Ofoefule, O.J. Afonne, E. Obi, K.C. Chilaka and C. Orish, 2000. Pharmacokinetics of diethylcarbamazine: Prediction by concentration in saliva. Biol. Pharm.. Bull., 23: 443-445.
Direct Link | - Afonne, O.J., O.E. Orisakwe, G.I. Ndubuka, D.D. Akumka and N. Ilondu, 2000. Zinc protection of mercury-induced hepatic toxicity in mice. Biol. Pharm. Bull., 23: 305-308.
PubMed | - Afonne, O.J., O.E. Orisakwe, E. Obi, C. Orish and D.D. Akumka, 2000. Some pharmacological properties of Synclisia scabrida III. Indian J. Pharmacol., 32: 239-241.
Direct Link | - Orisakwe, O.E., R. Asomugha, O.J. Afonne, E. Obi, K.C. Chilaka and C.E. Dioka, 1999. Effect of industrial effluents on water and soil qualities in Nnewi, Nigeria. J. Health Sci., 45: 177-183.
Direct Link | - Afonne, O.J. and O.E. Orisakwe, 1999. Cytokines in environmental toxicology Trop. J. Med. Res., 3: 1-8.
- Orisakwe, O.E., O.J. Afonne, C.F. Dioka and C.S. Ufearo, 1996. Investigation into the oestrogen-like activity of Synclisia scabrida. Fitoterapia, 67: 469-471.
Direct Link | - Orisakwe, O.E., O.J. Afonne, C.E. Dioka, C.S. Ufearo, A.N. Okpogba and S.I. Ofoefule, 1996. Some pharmacological properties of Synclisia scabrida II. Indian J. Med. Res., 103: 282-284.
PubMed |