Dr. Annoor Awadasseid

Postdoctoral Fellow
Zhejiang Univeristy of Technology, Zhejiang, China


Highest Degree
Ph.D. in Medical Chemistry from University of Chinese Academy of Sciences, Beijing, China

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Area of Interest:

Biomedical Sciences
Protein Purification
Gel Electrophoresis
Western Blot
Cell Culture

Selected Publications

  1. Wang, X., M. Zhang, X.Q. Xiong, H. Yang and P. Wang et al., 2022. Design, synthesis and bioactivity of novel naphthalimide-benzotriazole conjugates against A549 cells via targeting BCL2 G-quadruplex and inducing autophagy. Life Sci., Vol. 302. 10.1016/j.lfs.2022.120651.
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  2. Huang, Q., X. Wang, A. Chen, H. Zhang and Q. Yu et al., 2022. Design, synthesis and anti-tumor activity of novel benzothiophenonaphthalimide derivatives targeting mitochondrial DNA (mtDNA) G-quadruplex. Biochem. Pharmacol., Vol. 201. 10.1016/j.bcp.2022.115062.
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  3. Wen, X., Y. Wu, Y. Tanaka, A. Awadasseid, H. Tao and W. Zhang, 2021. Effect of 4,5-diazafluorene derivative on γδ T cell-mediated cytotoxicity against renal cell carcinoma. Life Sci., Vol. 269. 10.1016/j.lfs.2021.119066.
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  4. Wang, M., S. Jiang, M. Liu, L. Xu and S. Narva et al., 2021. Synthesis and anti-cancer activity of naphthopyrone derivatives. Tetrahedron Lett., Vol. 73. 10.1016/j.tetlet.2021.153111.
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  5. Ma, X., A. Awadasseid, K. Zhou, X. Wang and C. Shen et al., 2021. A 1,10-phenanthroline derivative selectively targeting telomeric G-quadruplex induces cytoprotective autophagy, causing apoptosis of gastric cancer cells. Life Sci., 10.1016/j.lfs.2021.120095.
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  6. Zhang, M., J. Liang, S.K. Jiang, L. Xu and Y.L. Wu et al., 2020. Design, synthesis and anti-cancer activity of pyrrole-imidazole polyamides through target-downregulation of c-kit gene expression. Eur. J. Med. Chem., Vol. 207. 10.1016/j.ejmech.2020.112704.
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  7. Jiang, S., A. Awadasseid, S. Narva, S. Cao and Y. Tanaka et al., 2020. Anti-cancer activity of benzoxazinone derivatives via targeting c-Myc G-quadruplex structure. Life Sci., Vol. 258. 10.1016/j.lfs.2020.118252.
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  8. Awadasseid, A., W. Li, Z. Liu, C. Qiao, J. Pang, G. Zhang and Y. Luo, 2020. Characterization of Camptotheca acuminata 10-hydroxygeraniol oxidoreductase and iridoid synthase and their application in biological preparation of nepetalactol in Escherichia coli featuring NADP+ - NADPH cofactors recycling. Int. J. Biol. Macromol., 162: 1076-1085.
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  9. Bakheet, A.M.H., S.A. Mahmoud, Y. Huang, J. Zhang and J. Wang et al., 2017. Ezrin as a possible diagnostic and/or prognostic biomarker in mice lymphatic metastatic hepatocellular carcinoma in vivo. BioFactors, 43: 662-672.
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  10. Awadasseid, A., K. Eugene, M. Jamal, J. Hou and A.M. Hago, et al., 2017. Effect of Coriolus versicolor glucan on the stimulation of cytokine production in sarcoma-180-bearing mice. Biomed. Rep., 7: 567-572.
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  11. Awadasseid, A., J. Hou, Y. Gamallat, S. Xueqi and K.D. Eugene et al., 2017. Purification, characterization, and antitumor activity of a novel glucan from the fruiting bodies of Coriolus versicolor. PLoS ONE, Vol. 12. 10.1371/journal.pone.0171270.
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  12. Kuugbee, E.D., X. Shang, Y. Gamallat, D. Bamba and A. Awadasseid et al., 2016. Structural change in microbiota by a probiotic cocktail enhances the gut barrier and reduces cancervia TLR2 signaling in a rat model of colon cancer. Dig. Dis. Sci., 61: 2908-2920.
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  13. Gamallat, Y., A. Meyiah, E.D. Kuugbee, A.M. Hago and G. Chiwala et al., 2016. Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model. Biomed. Pharmacother., 83: 536-541.
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