Dr. Balazs Sarkadi

Research Professor
Hungarian Academy of Sciences, Hungary


Highest Degree
PostDoc. in Cell Biology from University of Toronto, Canada

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Area of Interest:

Biomedical Sciences
Tissue Biomechanics
Membrane Protein
Pharmacology
Stem Cell

Selected Publications

  1. Klawitter, S., N.V. Fuchs, K.R. Upton, M. Munoz-Lopez and R. Shukla et al., 2016. Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells. Nat. commun., Vol. 7. 10.1038/ncomms10286.
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  2. Apáti, A., T. Berecz and B. Sarkadi, 2016. Calcium signaling in human pluripotent stem cells. Cell calcium, 59: 117-123.
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  3. Apati, A., K. Szebenyi, Z. Erdei, G. Varady, T.I. Orban and B. Sarkadi, 2016. The importance of drug transporters in human pluripotent stem cells and in early tissue differentiation. Expert Opin. Drug Metab. Toxicol., 12: 77-92.
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  4. Szebenyi, K., A. Furedi, O. Kolacsek, E. Pergel and Z. Bosze et al., 2015. Generation of a homozygous transgenic rat strain stably expressing a calcium sensor protein for direct examination of calcium signaling. Sci. Rep., Vol. 5. 10.1038/srep12645.
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  5. Pomozi, V., O.L. Saux, C. Brampton, A. Apana and A. Ilias et al., 2013. ABCC6 is a basolateral plasma membrane protein. Circulation Res., 112: 148-151.
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  6. Brozik, A., C. Hegedus, Z. Erdei, T. Hegedus, C. Ozvegy-Laczka, G. Szakacs and B. Sarkadi, 2011. Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: Substrates, chemosensitizers or inducers of acquired multidrug resistance. Expert Opinion Drug Metab. Toxicol., 7: 623-642.
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  7. Schneider, C.K., B. Sarkadi and P. Celis, 2010. Challenges with advanced therapy medicinal products and how to meet them. Nat. Rev. Drug Discov, 9: 195-201.
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  8. Sarkadi, B. and G. Szakacs, 2010. Understanding transport through pharmacological barriers-are we there yet. Nat. Rev. Drug Discovery, 9: 897-898.

  9. Orban, T.I., A. Apati, A. Nemeth, N. Varga and V. Krizsik et al., 2009. Applying a “Double‐Feature” promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon‐based gene delivery. Stem cells, 27: 1077-1087.
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  10. Szakacs, G., A. Varadi, C. Ozvegy-Laczka and B. Sarkadi, 2008. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox). Drug Dscovery Today, 13: 379-393.
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  11. Sarkadi, B., L. Homolya, G. Szakacs and A. Varadi, 2006. Human multidrug resistance ABCB and ABCG transporters: Participation in a chemoimmunity defense system. Physiol. Rev., 86: 1179-1236.
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  12. Elkind, N.B., Z. Szentpetery, A. Apati, C. Ozvegy-Laczka and G. Varady et al., 2005. Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib). Cancer Res., 65: 1770-1777.
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