Dr. Erika Di Zazzo

Adjunct Professor
Department of Biochemistry, Biophysics and General Pathology, Faculty of Medicine and Surgery, University of Naples, Italy


Highest Degree
Ph.D. in Signal Transduction Pathology from Second University of Naples, Naples, Italy

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Area of Interest:

Biomedical Sciences
Signal Transduction
Breast Cancer
Cell Proliferation
Cell Biology

Selected Publications

  1. Santacroce, L., C. Imbimbo, A. Ballini, F. Crocetto and S. Scacco et al., 2022. Testicular immunity and its connection with the microbiota. Physiological and clinical implications in the light of personalized medicine. J. Pers. Med., Vol. 12. 10.3390/jpm12081335.
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  2. Pagano, C., E. di Zazzo, G. Avilia, B. Savarese and G. Navarra et al., 2022. Advances in “adiponcosis”: insights in the inner mechanisms at the base of adipose and tumour tissues interplay. Int. J. Cancer, 10.1002/ijc.34355.
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  3. Iacovino, M.L., C.C. Miceli, M. de Felice, B. Barone and L. Pompella et al., 2022. Novel therapeutic opportunities in neoadjuvant etting in urothelial cancers: A new horizon opened by molecular classification and immune checkpoint inhibitors. Int. J. Mol. Sci., Vol. 23. 10.3390/ijms23031133.
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  4. Crocetto, F., G. Russo, E.D. Zazzo, P. Pisapia and B.F. Mirto et al., 2022. Liquid biopsy in prostate cancer management-current challenges and future perspectives. Cancers, Vol. 14. 10.3390/cancers14133272.
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  5. Boccellino, M., P. Ambrosio, A. Ballini, D. de Vito and S. Scacco et al., 2022. The role of curcumin in prostate cancer cells and derived spheroids. Cancers, Vol. 14. 10.3390/cancers14143348.
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  6. Bifulco, M., E.D. Zazzo, S. Pisanti, M. Martini and D. Orsini, 2022. The nineteenth-century experience of the kingdom of the two Sicilies on mandatory vaccination: An Italian phenomenon? Vaccine, 40: 3452-3454.
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  7. Bifulco, M., E.D. Zazzo, F. Napolitano, A.M. Malfitano and G. Portella, 2022. History of how viruses can fight cancer: From the miraculous healings to the approval of oncolytic viruses. Biochimie, 10.1016/j.biochi.2022.10.008.
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  8. Barone, B., A. Calogero, L. Scafuri, M. Ferro and G. Lucarelli et al., 2022. Immune checkpoint inhibitors as a neoadjuvant/adjuvant treatment of muscle-invasive bladder cancer: A systematic review. Cancers, Vol. 14. 10.3390/cancers14102545.
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  9. Aveta, A., C. Cacciapuoti, B. Barone, E.D. Zazzo and F.D. Giudice et al., 2022. The impact of meat intake on bladder cancer incidence: Is it really a relevant risk? Cancers, Vol. 14. 10.3390/cancers14194775.
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  10. Rienzo, M., E.D. Zazzo, A. Casamassimi, P. Gazzerro, G. Perini, M. Bifulco and C. Abbondanza, 2021. PRDM12 in health and diseases. Int. J. Mol. Sci., Vol. 22. 10.3390/ijms222112030.
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  11. Donato, M.D., A. Zamagni, G. Galasso, E.D. Zazzo and P. Giovannelliet al., 2021. The androgen receptor/filamin A complex as a target in prostate cancer microenvironment. Cell Death Dis. Vol. 12. 10.1038/s41419-021-03402-7.
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  12. Crocetto, F., E.d. Zazzo, C. Buonerba, A. Aveta and S.D. Pandolfoet al., 2021. Kaempferol, myricetin and fisetin in prostate and bladder cancer: A systematic review of the literature. Nutrients, Vol. 13. 10.3390/nu13113750.
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  13. Boccellino, M., G. Galasso, P. Ambrosio, P. Stiuso and S. Lamaet al., 2021. H9c2 Cardiomyocytes under Hypoxic Stress: Biological Effects Mediated by Sentinel Downstream Targets. Oxid. Med. Cell. Longevity, Vol. 2021. 10.1155/2021/6874146.
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  14. Zuchegna, C., E.D. Zazzo, B. Moncharmont and S. Messina, 2020. Dual-specificity phosphatase (DUSP6) in human glioblastoma: epithelial-to-mesenchymal transition (EMT) involvement. BMC Res. Notes, Vol. 13. 10.1186/s13104-020-05214-y.
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  15. Crocetto, F., M. Boccellino, B. Barone, E.D. Zazzo and A. Sciarraet al., 2020. The Crosstalk between Prostate Cancer and Microbiota Inflammation: Nutraceutical Products Are Useful to Balance This Interplay?. Nutrients, Vol. 12. 10.3390/nu12092648.
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  16. Casamassimi, A., M. Rienzo, E.D. Zazzo, A. Sorrentino and D. Fioreet al., 2020. Multifaceted Role of PRDM Proteins in Human Cancer. Int. J. Mol. Sci. Vol. 21. 10.3390/ijms21072648.
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  17. Di Zazzo, E., G. Galasso, P. Giovannelli, M. Di Donato and A. Di Santi et al., 2016. Prostate cancer stem cells: The role of androgen and estrogen receptors. Oncotarget, 7: 193-208.
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  18. Giovannelli, P., M. Di Donato, G. Cernera, A. Di Santi and G. Galasso et al., 2015. The dual role of androgen receptor in mesenchymal cells. Receptors Clin. Investigat., Vol. 2. .
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  19. Porcile, C., E. Di Zazzo, M.L. Monaco, G. D'Angelo and D. Passarella et al., 2014. Adiponectin receptors as novel regulators of cell proliferation in human glioblastoma. J. Cell. Physiol., 229: 1444-1454.
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  20. Di Zazzo, E., A. Feola, C. Zuchegna, A. Romano and C.F. Donini et al., 2014. The p85 regulatory subunit of PI3K mediates cAMP-PKA and insulin biological effects on MCF-7 cell growth and motility. Scient. World J., Vol. 2014. 10.1155/2014/565839.
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  21. Di Zazzo, E., C. De Rosa, C. Abbondanza and B. Moncharmont, 2013. PRDM proteins: Molecular mechanisms in signal transduction and transcriptional regulation. Biology, 2: 107-141.
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  22. Donini, C.F., E. Di Zazzo, C. Zuchegna, M. Di Domenico and S. D'Lnzeo et al., 2012. The p85α regulatory subunit of P13K mediates cAMP-PKA and retinoic acid biological effects on MCF7 cell growth and migration. Int. J. Oncol., 40: 1627-1635.
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  23. Abbondanza, C., C. De Rosa, A. D'Arcangelo, M. Pacifico and C. Spizuoco et al., 2012. Identification of a functional estrogen-responsive enhancer element in the promoter 2 of PRDM2 gene in breast cancer cell lines. J. Cell. Physiol., 227: 964-975.
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  24. Messina, S., C. Leonetti, C. Zuchegna, E. Di Zazzo, A. Calogero, L. Frati and A. Porcellini, 2011. Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas. Oncogene, 30: 3813-3820.
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  25. Di Zazzo, E. and B. Moncharmont, 2009. PRDM2 (PR domain containing 2, with ZNF domain). Atlas Genet. Cytogenet. Oncol. Haematol., 13: 24-27.

  26. Chambery, A., M. Pisante, A. Di Maro, E. Di Zazzo and M. Ruvo et al., 2007. Invariant Ser211 is involved in the catalysis of PD-L4, type I RIP from Phytolacca dioica leaves. PROTEINS: Struct. Funct. Bioinform., 67: 209-218.
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