Dr. Simona Perga
Research FellowUniversity of Turin, Italy
Highest Degree
Ph.D. in Molecular and Experimental Pathology from University of Turin, Italy
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Area of Interest:
Selected Publications
- Spadaro, M., F. Montarolo, S. Perga, S. Martire, F. Brescia, S. Malucchi and A. Bertolotto, 2017. Biological activity of glatiramer acetate on Treg and anti-inflammatory monocytes persists for more than 10years in responder multiple sclerosis patients. Clin. Immunol., 181: 83-88.
CrossRef | Direct Link | - Perga, S., S. Martire, F. Montarolo, N.D. Navone and A. Calvo et al., 2017. A20 in multiple sclerosis and parkinson's disease: clue to a common dysregulation of anti-inflammatory pathways? Neurotoxic. Res., 32: 1-7.
CrossRef | Direct Link | - Martire, S., N.D. Navone, F. Montarolo, S. Perga and A. Bertolotto, 2016. A gene expression study denies the ability of 25 candidate biomarkers to predict the interferon-beta treatment response in multiple sclerosis patients. J. Neuroimmunol., 15: 29-34.
CrossRef | Direct Link | - Perga, S., F. Montarolo, S. Martire, P. Berchialla, S. Malucchi and A. 2015. Anti-inflammatory genes associated with multiple sclerosis: A gene expression study. J. Neuroimmunol, 279: 75-78.
CrossRef | Direct Link | - Perga, S., A.A. Giuliano, K. Lis, N. Minari and S. Falvo et al., 2015. Vitamin D Binding Protein Isoforms and Apolipoprotein E in Cerebrospinal Fluid as Prognostic Biomarkers of Multiple Sclerosis. PLoS One 10.1371/journal.pone.0129291.
CrossRef | Direct Link | - Montarolo, F., S. Perga, Martire S. and A. Bertolotto, 2015. Nurr1 reduction influences the onset of chronic EAE in mice. Inflamm. Res., 64: 841-844.
Direct Link | - Navone, N.D., S. Perga, S. Martire, P. Berchialla, S. Malucchi and A. Bertolotto, 2014. Monocytes and CD4+ T cells contribution to the under-expression of NR4A2 and TNFAIP3 genes in patients with multiple sclerosis. J. Neuroimmunol., 272: 99-102.
CrossRef | Direct Link | - Montarolo, F., C. Raffaele, S. Perga, S. Martire and A. Finardi et al., 2014. Effects of isoxazolo-pyridinone 7e, a potent activator of the Nurr1 signaling pathway, on experimental autoimmune encephalomyelitis in mice. PLoS One, 10.1371/journal.pone.0108791.
CrossRef | Direct Link | - Navone, N.D., S. Perga, S. Martire, F. Montarolo, P. Berchialla and A. Bertolotto, 2013. Expression of six inflammation-related genes in monocytes and CD4+ T lymphocytes from patients with multiple sclerosis. Multiple Sclerosis J., .
Direct Link | - Perga, S., A.G. Albo, K. Lis, N. Minari and F. Marnetto et al., 2012. Extracellular Actin Scavenger System as a diagnostic/prognosis tool in multiple sclerosis. J. Neuroimmunol., 253 : 21-22.
- Montarolo, F., S. Perga, S. Martire, A. Bertolotto, 2012. Altered nr4a subfamily gene expression level in peripheral blood of parkinson’s and alzheimer’s disease patients. Neurotoxic. Res., 30: 338-344.
Direct Link | - Gilli, F., N.D. Navone, S. Perga, C. Cosentino and C. Barlassina et al., 2012. The microRNAs miR-183 and miR-9-2 target Nurr1 and SOCS2 genes, establishing a negative feedback loop that inhibits inflammation in multiple sclerosis. J. Neuroimmunol., 253: 62-62.
- Robotti, A., M. Natale, A.A. Giuliano, K. Lis and S. Perga et al., 2011. Acute-phase proteins investigation based on lectins affinity capture prior to 2-DE separation: Application to serum from multiple sclerosis patients. Electrophoresis, 31: 2882-2893.
CrossRef | Direct Link | - Martin, M.G., L. Trovò, S. Perga, A. Sadowsk, A. Rasola, F. Chiara and C.G. Dotti, 2011. Cyp46-mediated cholesterol loss promotes survival in stressed hippocampal neurons. Neurobiol. Aging., 32: 933-943.
CrossRef | Direct Link | - Gilli, F., N.D. Navone, S. Perga, F. Marnetto and M. Caldano et al., 2011. Loss of braking signals during inflammation: a factor affecting the development and disease course of multiple sclerosis. Arch. Neurol., 68: 879-888.
CrossRef | Direct Link | - Bertolotto, A., N.D. Navone, S. Perga, A. Pulizzi, F. Marnetto, F. Gilli, 2011. Dysregulated gene expression pattern of anti-inflammatory transcripts in monocytes and t-lymphocytes from patients with multiple sclerosis. Neurology, .
- Bertolotto, A., N.D. Navone, P. Valentino, M. Caldano, S. Perga, S. Malucchi and F. Gilli, 2011. Clinical response to glatiramer acetate correlates with the ex vivo GA induced IFN gamma and IL4 mRNA response in patients with multiple sclerosis. Neurology, .
- Gilli, F., N.D. Navone, P. Valentino, L. Granieri, S. Perga, S. Malucchi and A. Bertolotto, 2010. Classification of individuals based on ex-vivo glatiramer acetate-induced interferon-γ and interleukin-4 response. Mult. Scler., 18: 1484-1492.
Direct Link | - Bertolotto, A., N.D. Navone, S. Perga, A. Pulizzi and F. Gilli, 2010. Dysregulated expression pattern of anti-inflammatory transcripts in monocytes and T lymphocytes from patients with Multiple Sclerosis. Neurology, .
- Bertolotto, A., N.D. Navone, S. Malucchi, P. Valentino and A. di Sapio et al., 2010. Overlapping molecular mechanisms of protection during pregnancy and disease-modifying therapies in patients with multiple sclerosis. Neurology, 74: 158-159.
- Gilli, F., N.D. Navone, P. Valentino, S. Perga, F. Marnetto and A. Bertolotto, 2009. Overlapping Molecular mechanisms of protection during pregnancy and disease-modifying therapies in patients with multiple sclerosis. Multiple Sclerosis, .
- Perga, S., M.G. Martin, L. Trovò, A. Rasola and P. Holm et al., 2008. Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro. Mol. Biol. Cell. 19: 2101-2112.
CrossRef | Direct Link | - Crameri, A., E. Biondi, K. Kuehnle, D. Lutjohann and K.M. Thelen et al., 2006. The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Aβ generation in vivo. EMBO J., 25: 432-443.
Direct Link | - Abad-Rodriguez, J., Ledesma M.D., Craessaerts K., Perga S. and M. Medina et al., 2004. Neuronal membrane cholesterol loss enhances amyloid peptide generation. J. Cell Biol., 167: 953-960.
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