Dr. Gianluca Serafini
Research ScientistSapienza University of Rome, Italy
Highest Degree
Ph.D. in Psychiatry from Sapienza University of Rome, Italy
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Biography
Dr. Gianluca Serafini is currently working at Sant’Andrea Hospital, Sapienza University of Rome. He has completed his Ph.D. in Psychiatry from Sapienza University of Rome, Italy. His main area of interest focuses on Pharmacology and Toxicology, Biomedical Sciences, and Molecular Sciences. His area of expertise includes Neurobiology of Major Affective Disorders, Suicide and Suicide Prevention, Psychopharmacology, and Early Interventions in Psychosis. He has published 68 research articles in international journals, 7 articles in national journals, 33 chapters in national and international books, and 92 presentations contributed as author/co-author.
Area of Interest:
Selected Publications
- Serafini, G., M. Pompili, M. Innamorati, Y. Dwivedi, G. Brahmachari and P. Girardi, 2013. Pharmacological properties of glutamatergic drugs targeting NMDA receptors and their application in major depression. Curr. Pharm. Des., 19: 1898-1922.
CrossRef | PubMed | - Pompili, M., D. Lester, G. Dominici, L. Longo and G. Marconi et al., 2013. Indications for electroconvulsive treatment in schizophrenia: A systematic review. Schizophr Res., 146: 1-9.
CrossRef | PubMed | Direct Link | - Pompili, M., A. Pennica, G. Serafini, M. Battuello and M. Innamorati et al., 2013. Depression and affective temperaments are associated with poor health-related quality of life in patients with HIV infection. J. Psychiatr Pract., 19: 109-117.
CrossRef | PubMed | Direct Link | - Innamorati, M., M. Pompili, G. Martinotti, G. Serafini and M. Amore et al., 2013. Trends in alcohol-related deaths in the EU countries in 1980-2003. Int. J. Soc. Psychiatry, 59: 443-451.
CrossRef | PubMed | Direct Link | - Innamorati, M., G. Serafini, D. Lester, M. Amore, P. Girardi and M. Pompili, 2013. Violent deaths among Russian and EU male older adults. Int. J. Soc. Psychiatry, 10.1177/0020764012467261.
CrossRef | PubMed | Direct Link | - Iliceto, P., M. Pompili, G. Candilera, G. Borges and D.A. Lamis et al., 2013. Suicide risk and psychopathology in immigrants: a multi-group confirmatory factor analysis. Soc. Psychiatry Psychiatr. Epidemiol., 48: 1105-1114.
CrossRef | PubMed | Direct Link | - Serafini, G., M. Pompili, M. Innamorati, Z. Rihmer, L. Sher and P. Girardi, 2012. Can cannabis increase the suicide risk in psychosis? A critical review. Curr. Pharm. Des., 18: 5165-5187.
CrossRef | PubMed | - Serafini, G., M. Pompili, M. Innamorati, G. Giordano and F. Montebovi et al., 2012. The role of microRNAs in synaptic plasticity, major affective disorders and suicidal behavior. Neurosci. Res., 73: 179-190.
CrossRef | PubMed | Direct Link | - Serafini, G., M. Pompili, M. Innamorati, G. Gentile and M. Borro, 2012. Gene variants with suicidal risk in a sample of women with chronic migraine and affective temperamental dysregulation. Eur. Rev. Med. Pharmacol. Sci., 16: 1389-1398.
PubMed | Direct Link | - Serafini, G., M. Pompili, M. Innamorati, A. Negro and M. Fiorillo et al., 2012. White matter hyperintensities and self-reported depression in a sample of patients with chronic headache. J. Headache Pain, 13: 661-667.
CrossRef | PubMed | Direct Link | - Serafini, G., 2012. Neuroplasticity and major depression, the role of modern antidepressant drugs. World J. Psychiatr., 2: 49-57.
CrossRef | Direct Link | - Pompili, M., Z. Rihmer, X. Gonda, G. Serafini, L. Sher and P. Girardi, 2012. Early onset of action and sleep-improving effect are crucial in decreasing suicide risk: The role of quetiapine XR in the treatment of unipolar and bipolar depression. Riv. Psichiatr., 47: 489-497.
CrossRef | PubMed | Direct Link | - Pompili, M., Z. Rihmer, H. Akiskal, M. Amore and X. Gonda et al., 2012. Temperaments mediate suicide risk and psychopathology among patients with bipolar disorders. Compr. Psychiatry, 53: 280-285.
CrossRef | PubMed | Direct Link | - Pompili, M., S. Gibiino, M. Innamorati, G. Serafini and A. Del Casale et al., 2012. Prolactin and thyroid hormone levels are associated with suicide attempts in psychiatric patients. Psychiatry Res., 200: 389-394.
CrossRef | PubMed | Direct Link | - Pompili, M., P. Venturini, S. Campi, M.E. Seretti and F. Montebovi et al., 2012. Do stroke patients have an increased risk of developing suicidal ideation or dying by suicide? An overview of the current literature. CNS Neurosci. Ther., 18: 711 -721.
CrossRef | PubMed | Direct Link | - Pompili, M., M. Innamorati, Z. Rihmer, X, Gonda and G. Serafini, 2012. Cyclothymic-depressive-anxious temperament pattern is related to suicide risk in 346 patients with major mood disorders. J. Affect Disord., 136: 405-411.
CrossRef | PubMed | Direct Link | - Pompili, M., M. Innamorati, G. Serafini, X. Gonda and S. Campi et al., 2012. How does subjective experience of pain relate to psychopathology among psychiatric patients? Gen. Hosp. Psychiatry, 34: 534-540.
CrossRef | PubMed | Direct Link | - Pompili, M., M. Innamorati, D. Lester, G. Serafini and D. Erbuto e tla., 2012. Suicide attempts in acute psychiatric referrals with substance use disorders. Riv. Psichiatr., 47: 313 -318.
CrossRef | PubMed | Direct Link | - Pompili, M., G. Serafini, M. Innamorati, F. Montebovi and M. Palermo et al., 2012. Car accidents as a method of suicide: A comprehensive overview. Forensic Sci. Int., 223: 1-9.
CrossRef | PubMed | Direct Link | - Pompili, M., G. Serafini, M. Biondi, M. Biondi and A. Siracusano et al., 2012. Substance abuse and suicide risk among adolescents. Eur. Arch. Psychiatry Clin. Neurosci., 262: 469-485.
CrossRef | PubMed | Direct Link | - Pompili, M., A. Forte, M. Palermo, H. Stefani and D.A. Lamis et al., 2012. Suicide risk in multiple sclerosis: A systematic review of current literature. J. Psychosom Res., 73: 411-417.
CrossRef | PubMed | Direct Link | - Iliceto, P., M. Pompili, G. Candilera, M.A. Natali and H. Stefani et al., 2012. Gender-related differences concerning anger expression and interpersonal relationships in a sample of overweight/obese subjects. Clin. Ter., 163: e279-e285.
PubMed | Direct Link | - Gonda, X., M. Pompili, G. Serafini, F. Montebovi and S. Campi et al., 2012. Suicidal behavior in bipolar disorder: Epidemiology, characteristics and major risk factors. J. Affect Disord., 143: 16-26.
CrossRef | PubMed | Direct Link | - Fusar-Poli, P., R. Smieskova, G. Serafini, P. Politi and S. Borgwardt, 2012. Neuroanatomical markers of genetic liability to psychosis and first episode psychosis: A voxelwise meta-analytical comparison. World J. Biol. Psychiatry, 10.3109/15622975.2011.630408.
PubMed | Direct Link | - Tatarelli, R., G. Serafini, M. Innamorati, D. Lester, P. Girardi and M. Pompili, 2011. Psychiatric diagnoses during institutionalization: An investigation of 1334 psychiatric patients hospitalized in an Italian asylum during the 20th Century. Wien Klin Wochenschr, 123: 135-144.
CrossRef | PubMed | Direct Link | - Serafini, G., M. Pompili, R. Haghighat, D. Pucci and M. Pastina et al., 2011. Stigmatization of schizophrenia as perceived by nurses, medical doctors, medical students and patients. J. Psychiatr Ment Health Nurs., 18: 576-585.
CrossRef | PubMed | Direct Link | - Serafini, G., M. Pompili, M. Innamorati, P. Fusar-Poli and H.S. Akiskal et al., 2011. Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders. J. Affect Disord., 129: 47-55.
CrossRef | PubMed | Direct Link | - Serafini, G., M. Pompili, M. Innamorati, G. Giordano and R. Tatarelli et al., 2011. Glycosides, depression and suicidal behaviour: The role of glycoside-linked proteins. Molecules, 16: 2688-2713.
CrossRef | PubMed | Direct Link | - Serafini, G., M. Pompili, M. Fusar-Poli, G. Porfiri and G. Giordano et al., 2011. Bupropion and panic disorder: Case report and review of the literature. J. Neuropsychiatr Clin. Neurosci., 23: E47-E50.
PubMed | Direct Link | - Serafini, G., M. Pompili, M. Angelone, D. Lester, R. Tatarelli and P. Girardi, 2011. Clinical and functional outcome in a subject with bipolar disorder and severe white matter hyperintensities. Eur. J. Psychiatry, 25: 41-45.
CrossRef | Direct Link | - Scuderi, G., M. Pompili, M. Innamorati, N. Pasquale and S. Pontremolesi et al., 2011. Affective temperaments are associated with higher hopelessness and perceived disability in patients with open-angle glaucoma. Int. J. Clin. Pract., 65: 976-984.
CrossRef | PubMed | Direct Link | - Pompili, M., P. Venturini, M. Innamorati, G. Serafini and L. Telesforo et al., 2011. The role of asenapine in the treatment of manic or mixed states associated with bipolar I disorder. Neuropsychiatr Dis. Treat., 7: 259-265.
CrossRef | PubMed | Direct Link | - Pompili, M., P. Iliceto, D. Luciano, M. Innamorati and G. Serafini et al., 2011. Higher hopelessness and suicide risk predict lower self-deception among psychiatric patients and non-clinical individuals. Riv. Psichiatr., 46: 24-30.
CrossRef | PubMed | Direct Link | - Pompili, M., M. Innamorati, P. Venturini, G. Serafini, D. Lester and P. Girardi, 2011. Child abuse as a risk factor for suicide in life: A selective overview. Min Psichiatr., 52: 61-69.
Direct Link | - Pompili, M., M. Innamorati, M. Vichi, M. Masocco and N. Vanacore et al., 2011. Inequalities and impact of socioeconomic-cultural factors in suicide rates across Italy. Crisis, 32: 178-185.
CrossRef | PubMed | Direct Link | - Pompili, M., M. Innamorati, G. Serafini, A. Forte and A. Cittadini et al., 2011. Suicide attempters in the emergency department before hospitalization in a psychiatric ward. Perspect. Psychiat. Care, 47: 23-34.
CrossRef | PubMed | Direct Link | - Pompili, M., G. Serafini, M. Innamorati, E. Ambrosi and L. Telesforo et al., 2011. Unmet treatment needs in schizophrenia patients: Is asenapine a potential therapeutic option? Expert Rev. Neurother., 11: 989-1006.
CrossRef | PubMed | Direct Link | - Pompili, M., G. Serafini, M. Innamorati, D. Lester and A. Shrivastava et al., 2011. Suicide risk in first episode psychosis: A selective review of the current literature. Schiz Res., 129: 1-11.
CrossRef | PubMed | Direct Link | - Innamorati, M., M. Pompili, X. Gonda, M. Amore and G. Serafini et al., 2011. Psychometric properties of the Gotland Scale for Depression in Italian psychiatric inpatients and its utility in the prediction of suicide risk. J. Affective Disorders, 132: 99-103.
CrossRef | PubMed | Direct Link | - Innamorati, M., M. Pompili, G. Serafini, D. Lester and D. Erbuto et al., 2011. Psychometric properties of the suicidal history self-rating screening scale. Arch. Suicide Res., 15: 87-92.
CrossRef | PubMed | Direct Link | - Innamorati, M., D. De Leo, Z. Rihmer, G. Serafini and D. Lester et al., 2011. Tobacco smoking and suicidal ideation in school-aged children 12-15 years old: Impact of cultural differences. J. Addict Dis., 30: 359-367.
CrossRef | PubMed | Direct Link | - Girardi, P., M. Pompili, M. Innamorati, G. Serafini and C. Berrettoniet al., 2011. Temperament, post-partum depression, hopelessness, and suicide risk among women soon after delivering. Women Health, 51: 511-524.
CrossRef | PubMed | Direct Link | - Serafini, G., M. Pompili, M. Innamorati, P. De Rossi, S. Ferracuti, P. Girardi and R. Tatarelli, 2010. Deep white matter hyperintensities as possible predictor of poor prognosis in a sample of patients with late-onset bipolar II disorder. Bipolar Disord., 12: 755-756.
CrossRef | PubMed | Direct Link | - Serafini, G., M. Pompili, M. Innamorati, G. Iacorossi and I. Cuomo et al., 2010. The impact of anxiety, depression, and suicidality on quality of life and functional status of patients with congestive heart failure and hypertension: an observational cross-sectional study. Prim Care Compan. J. Clin. Psychiatry, 12: e1-e9.
CrossRef | PubMed | Direct Link | - Serafini, G., M. Pompili, L. Bancheri, D. Pucci and S. Rigucci et al., 2010. Personality profiles in patients with bulimia and obesity: an investigation with the MMPI-2. Quaderni italiani di Psichiatria, 29: 59-65.
CrossRef | Direct Link | - Serafini, G., M. Pompili, A. Del Casale, M. Mancini and M. Innamorati et al., 2010. Duloxetine versus venlafaxine in the treatment of unipolar and bipolar depression. Clin Ter., 161: 321-327.
PubMed | Direct Link | - Rigucci, S., G. Serafini, M. Pompili, G.D. Kotzalidis and R. Tatarelli, 2010. Anatomical and functional correlates in major depressive disorder: The contribution of neuroimaging studies. World J. Biol. Psychiatry, 11: 165-180.
CrossRef | PubMed | Direct Link | - Pompili, M., M. Innamorati, M. Vichi, M. Masocco and N. Vanacore et al., 2010. Suicide prevention among youths. Systematic review of available evidence-based interventions and implications for Italy. Minerva Pediatr., 62: 507-535.
PubMed | Direct Link | - Pompili, M., M. Innamorati, G. Giupponi, R. Pycha and G. Serafini et al., 2010. Patients with mood disorders admitted for a suicide attempt to an emergency ward. Neuropsychiatrie, 24: 56-63.
PubMed | - Pompili, M., G. Serafini, M. Innamorati, G. Serra and G. Dominici et al., 2010. Patient outcome in migraine prophylaxis: The role of psychopharmacological agents. Patient Related Outcome Measures, 1: 107-118.
CrossRef | PubMed | Direct Link | - Pompili, M., G. Serafini, M. Innamorati, G. Serra and A. Forte et al., 2010. White matter hyperintensities, suicide risk and late-onset affective disorders: An overview of the current literature. Clin Ter., 161: 555-563.
PubMed | Direct Link | - Pompili, M., G. Serafini, M. Innamorati, G. Dominici and S. Ferracuti et al., 2010. Suicidal behavior and alcohol abuse. Int. J. Environ. Res. Public Health, 7: 1392-1431.
CrossRef | PubMed | Direct Link | - Pompili, M., G. Serafini, M. Innamorati, E. Ambrosi and G. Giordano et al., 2010. Antidepressants and suicide risk: A comprehensive overview. Pharmaceuticals, 3: 2861-2883.
CrossRef | Direct Link | - Pompili, M., G. Serafini, M. Innamorati, A.M. Moller-Leimkuhler and G. Giupponi et al., 2010. The hypothalamic-pituitary-adrenal axis and serotonin abnormalities: A selective overview for the implications of suicide prevention. Eur. Arch. Psychiatry Clin. Neurosci., 260: 583-600.
CrossRef | PubMed | Direct Link | - Pompili, M., G. Serafini, D. Di Cosimo, G. Dominici and M. Innamorati et al., 2010. Psychiatric comorbidity and suicide risk in patients with chronic migraine. Neuropsychiat. Dis. Treatment, 6: 81-91.
CrossRef | PubMed | Direct Link | - Girardi, P., G. Serafini, M. Pompili, M. Innamorati, R. Tatarelli and R.J. Baldessarini, 2010. Prospective, open study of long-acting injected risperidone versus oral antipsychotics in 88 chronically psychotic patients. Pharmacopsychiatry, 43: 66-72.
CrossRef | PubMed | Direct Link | - Pompili, M., M. Innamorati, A. Del Casale, G. Serafini and A. Forte et al., 2009. No cathartic effect in suicide attempters admitted to the emergency department. J. Psychiatric Pract., 15: 433-441.
CrossRef | PubMed | Direct Link | - Pompili, M., I. Cuomo, I. Innamorati, D. Lester and A. Forte et al., 2009. High lethality suicide attempts among chronic schizophrenia patients. Clin. Neuropsychiatry, 6: 202-207.
Direct Link | - Pompili, M., G. Serafini, A. Del Casale, S. Rigucci and M. Innamorati et al., 2009. Improving adherence in mood disorders: The struggle against relapse, recurrence and suicide risk. Expert Rev. Neurother., 9: 985-1004.
CrossRef | PubMed | Direct Link | - Girardi, P., M. Pompili, M. Innamorati, G. Serafini and A. Del Casale et al., 2009. Duloxetine: A metanalysis of a most recent studies. Human Phychopharmacol., 24: 177-190.
- Pompili, M., M. Innamorati, J.J. Mann, M.A. Oquendo and D. Lester et al., 2008. Periventricular white matter hyperintensities as predictors of suicide attempts in bipolar disorders and unipolar depression. Prog. Neuropsychopharmacol. Biol. Psychiatry, 32: 1501-1507.
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