Dr. Ruxandra Mckinnon

Post-doctoral Fellow
University of Vienna, Austria

Highest Degree
Doctorate in Natural Sciences from University of Vienna, Austria

My URL
https://livedna.org/40.5933

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Area of Interest:

Biomedical Sciences
Cell Culture
Cell Biology
Molecular Biology
Natural Products

Selected Publications

  1. Unger, C., R. Popescu, B. Giessrigl, D. Laimer and S. Heider et al., 2013. The dichloromethane extract of the ethnomedicinal plant Neurolaena lobata inhibits NPM/ALK expression which is causal for anaplastic large cell lymphomagenesis. Int. J. Oncol., 42: 338-348.
    CrossRef  |  PubMed  |  Direct Link  |  

  2. Popescu, R. and B. Kopp, 2013. The genus Rhododendron: An ethnopharmacological and toxicological review. J. Ethnopharmacol., 147: 42-62.
    CrossRef  |  PubMed  |  Direct Link  |  

  3. Unger, C., R. Popescu, B. Giessrigl, L. Rarova and I. Herbacek et al., 2012. An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis. Int. J. Oncol., 40: 2131-2139.
    CrossRef  |  PubMed  |  Direct Link  |  

  4. Seelinger, M., R. Popescu, P. Seephonkai, J. Singhuber and B. Giessrigl et al., 2012. Fractionation of an extract of Pluchea odorata separates a property indicative for the induction of cell plasticity from one that inhibits a neoplastic phenotype. Evid. Based Complement. Alternat. Med. 10.1155/2012/701927.
    CrossRef  |  PubMed  |  Direct Link  |  

  5. Seelinger, M., R. Popescu, B. Giessrigl, K. Jarukamjorn and C. Unger et al., 2012. Methanol extract of the ethnopharmaceutical remedy Smilax spinosa exhibits anti-neoplastic activity. Int. J. Oncol., 41: 1164-1172.
    CrossRef  |  PubMed  |  Direct Link  |  

  6. Rozema, E., R. Popescu, H. Sonderegger, C.W. Huck and J. Winkler et al., 2012. Characterization of glucocerebrosides and the active metabolite 4,8-sphingadienine from Arisaema amurense and Pinellia ternate by NMR and CD spectroscopy and ESI-MS/CID-MS. J. Agric. Food Chem., 60: 7204-7210.
    CrossRef  |  PubMed  |  Direct Link  |  

  7. Kizaibek, M., R. Popescu, S. Prinz, H. Upur, J. Singhuber, M. Zehl and B. Kopp, 2012. Towards modernization of the formulation of the traditional uighur medicine herbal preparation Abnormal Savda Munziq. Evid. Based Complement. Alternat. Med 10.1155/2012/863101.
    CrossRef  |  Direct Link  |  

  8. Vlashi, E., C. Lagadec, L. Vergnes, T. Matsutani and K. Masui et al., 2011. Metabolic state of glioma stem cells and nontumorigenic cells. Proc. Nat. Acad. Sci. United States Am., 108: 16062-16067.
    CrossRef  |  Direct Link  |  

  9. Seephonkai, P., R. Popescu, M. Zehl, G. Krupitza, E. Urban and B. Kopp, 2011. Ferruginenes A-C from Rhododendron ferrugineum and their cytotoxic evaluation. J. Nat. Prod., 74: 712-717.
    CrossRef  |  PubMed  |  Direct Link  |  

  10. Popescu, R., E.H. Heiss, F. Ferk, A. Peschel and S. Knasmueller et al., 2011. Ikarugamycin induces DNA damage, intracellular calcium increase, p38 MAP kinase activation and apoptosis in HL-60 human promyelocytic leukemia cells. Mutat. Res./Fundamen. Mol. Mech. Mutagen., 709-710: 60-66.
    CrossRef  |  PubMed  |  Direct Link  |  

  11. Gao, H., R. Popescu, B. Kopp and Z. Wang, 2011. Bufadienolides and their antitumor activity. Nat. Prod. Rep., 28: 953-969.
    CrossRef  |  PubMed  |  Direct Link  |  

  12. Bauer, S., J. Singhuber, M. Seelinger, C. Unger and K. Viola et al., 2011. Separation of anti-neoplastic activities by fractionation of a Pluchea odorata extract. Front. Biosci., (Elite Ed.), 3: 1326-1336.
    PubMed  |  Direct Link  |  

  13. Madlener, S., P. Saiko, K. Viola, N. Huttary and N. Stark et al., 2010. Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest and inhibition of lymphendothelial gap formation In Vitro. Br. J. Can., 102: 1361-1370.
    PubMed  |  Direct Link  |  

  14. Gridling, M., R. Popescu, B. Kopp, K.H. Wagner, L. Krenn and G. Krupitza, 2010. Anti-leukaemic effects of two extract types of Lactuca sativa correlate with the activation of Chk2, induction of p21, downregulation of cyclin D1 and acetylation of α-tubulin. Oncol. Rep., 23: 1145-1151.

  15. Stark, N., M. Gridling, S. Madlener, S. Bauer and A. Lackner et al., 2009. A polar extract of the Maya healing plant Anthurium schlechtendalii (Aracea) exhibits strong In vitro anticancer activity. Int. J. Mol. Med., 24: 513-521.
    CrossRef  |  PubMed  |  

  16. Kizaibek, M., B. Kopp, S. Prinz, R. Popescu and H. Upur, 2009. Antiproliferative activity of individual herbs of abnormal savda Munziq on HL-60 cells. Sci. Technol. Rev., 27: 94-98.
    Direct Link  |  

  17. Gridling, M., N. Stark, S. Madlener, A. Lackner and R. Popescu et al., 2009. In vitro anti-cancer activity of two ethno-pharmacological healing plants from Guatemala Pluchea odorata and Phlebodium decumanum. Int. J. Oncol., 34: 1117-1128.
    CrossRef  |  PubMed  |  Direct Link  |  

  18. Bader, Y., S. Madlener, S. Strasser, S. Maier and P. Saiko et al., 2008. Stilbene analogues affect cell cycle progression and apoptosis independently of each other in an MCF-7 array of clones with distinct genetic and chemoresistant backgrounds. Oncol. Rep., 19: 801-810.
    PubMed  |  Direct Link  |  

  19. Popescu, R. and C.E. Gard, 2005. Phytochemical research on Rhododendron kotschyi Simk. (Ericaceae) homeopathic tincture. Timisoara Med. J., 55: 346-347.
Member since December, 2013