Dr. Soriano Ursua Marvin Antonio

Professor
Instituto Politecnico Nacional, Mexico

Highest Degree
Ph.D. in Medicine from Instituto Politecnico Nacional, Mexico

My URL
https://livedna.org/52.6336

Share this Profile

Area of Interest:

Medicine
Medicinal Chemistry
Molecular Modelling
Neurology
Drug Targets

Selected Publications

  1. Soriano-Ursua, M.A., M. Bello, C.F. Hernandez-Martinez, I. Santillan-Torres and R. Guerrero-Ramirez et al., 2019. Cell-based assays and molecular dynamics analysis of a boron-containing agonist with different profiles of binding to human and guinea pig beta2 adrenoceptors. Eur. Biophys. J., 48: 83-97.
    CrossRef  |  Direct Link  |  

  2. Demianenko, E., A. Rayevsky, M.A. Soriano-Ursua and J.G. Trujillo-Ferrara, 2019. Theoretical coupling and stability of boronic acid adducts with catecholamines. Lett. Drug Des. Discov., 16: 467-475.
    CrossRef  |  Direct Link  |  

  3. Correa-Basurto, A.M., A. Romero-Castro, J. Correa-Basurto, M. Hernandez-Rodriguez and M.A. Soriano-Ursua et al., 2019. Pharmacokinetics and tissue distribution of N-(2-hydroxyphenyl)-2-propylpentanamide in Wistar rats and its binding properties to human serum albumin. J. Pharmaceut. Biomed. Anal., 162: 130-139.
    CrossRef  |  Direct Link  |  

  4. Coaviche-Yoval, A., H. Luna, R. Tovar-Miranda, M.A. Soriano-Ursua and J.G. Trujillo-Ferrara, 2019. Synthesis and biological evaluation of novel 2,3-disubstituted benzofuran analogues of GABA as neurotropic agents. Med. Chem., 15: 77-86.
    CrossRef  |  Direct Link  |  

  5. Segura-Uribe, J.J., E.D. Farfan-Garcia, C. Guerra-Araiza, F.J. Cipres-Flores, P. Garcia-dela Torre and M.A. Soriano-Ursua, 2018. Differences in brain regions of three mice strains identified by label-free micro-Raman. Spectrosc. Lett., 51: 356-366.
    CrossRef  |  Direct Link  |  

  6. Pinto-Almazan, R., J.J. Segura-Uribe, M.A. Soriano-Ursua, E.D. Farfan-Garcia, J.M. Gallardo and C. Guerra-Araiza, 2018. Effect of tibolone pretreatment on kinases and phosphatases that regulate the expression and phosphorylation of Tau in the hippocampus of rats exposed to ozone. Neural Regener. Res., 13: 440-448.
    CrossRef  |  PubMed  |  Direct Link  |  

  7. Ocampo-Nestor, A.L., R.M. Lopez-Mayorga, E.F. Castillo-Henkel, I.I. Padilla-Martinez, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2018. Design, synthesis and in vitro evaluation of a Dopa-organoboron compound that acts as a bladder relaxant through non-catecholamine receptors. Mol. Diversity, (In Press). 10.1007/s11030-018-9883-7.
    CrossRef  |  Direct Link  |  

  8. Lopez-Cabrera, Y., E.L. Castillo-Garcia, J.A. Altamirano-Espino, T. Perez-Capistran, E.D. Farfan-Garcia, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2018. Profile of three boron-containing compounds on the body weight, metabolism and inflammatory markers of diabetic rats. J. Trace Elem. Med. Biol., 50: 424-429.
    CrossRef  |  Direct Link  |  

  9. Farfan-Garcia, E.D., E.L. Castillo-Garcia and M.A. Soriano-Ursua, 2018. More than boric acid: Increasing relevance of boron in medicine. World J. Transl. Med., 7: 1-4.
    CrossRef  |  Direct Link  |  

  10. Bello, M., C. Guadarrama-Garcia, L.M. Velasco-Silveyra, E.D. Farfan-Garcia and M.A. Soriano-Ursua, 2018. Several effects of boron are induced by uncoupling steroid hormones from their transporters in blood. Med. Hypotheses, 118: 78-83.
    CrossRef  |  Direct Link  |  

  11. Andrade-Jorge, E., L.A. Sanchez-Labastida, M.A. Soriano-Ursua, J.A. Guevara-Salazar and J.G. Trujillo-Ferrara, 2018. Isoindolines/isoindoline-1,3-diones as AChE inhibitors against Alzheimer's disease, evaluated by an improved ultra-micro assay. Med. Chem. Res., 27: 2187-2198.
    CrossRef  |  Direct Link  |  

  12. Andrade-Jorge, E., J. Bribiesca-Carlos, F.J. Martinez-Martinez, M.A. Soriano-Ursua, I.I. Padilla-Martinez and J.G. Trujillo-Ferrara, 2018. Crystal structure, DFT calculations and evaluation of 2-(2-(3,4-dimethoxyphenyl)ethyl)isoindoline-1,3-dione as AChE inhibitor. Chem. Cent. J., Vol. 12. 10.1186/s13065-018-0442-1.
    CrossRef  |  Direct Link  |  

  13. Andrade-Jorge, E., A.K. Garcia-Avila, A.L. Ocampo-Nestor, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2018. Advances of bioinformatics applied to development and evaluation of boron-containing compounds. Curr. Org. Chem., 22: 298-306.
    CrossRef  |  Direct Link  |  

  14. Perez-Rodriguez, M., E. Garcia-Mendoza, E.D. Farfan-Garcia, B.C. Das and F.J. Cipres-Flores et al., 2017. Not all boronic acids with a five-membered cycle induce tremor, neuronal damage and decreased dopamine. NeuroToxicology, 62: 92-99.
    CrossRef  |  Direct Link  |  

  15. Perez, T., E.D. Farfan-Garcia, M.A. Soriano-Ursua, L. Manuel-Apolinar and M.C. Castillo et al., 2017. Effects of hydrogen peroxide on phenylephrine-induced contraction of abdominal or thoracic aorta from adult rats. Int. J. Clin. Exp. Pathol., 10: 5105-5116.
    Direct Link  |  

  16. Ocampo-Nestor, A.L., J.G. Trujillo-Ferrara, A. Abad-Garcia, C. Reyes-Lopez, S. Geninatti-Crich and M.A. Soriano-Ursua, 2017. Boron's journey: Advances in the study and application of pharmacokinetics. Expert Opin. Therapeut. Patents, 27: 203-215.
    CrossRef  |  Direct Link  |  

  17. Neri-Bazan, R.M., J. Garcia-Machorro, D. Mendez-Luna, L.E. Tolentino-Lopez and F. Martinez-Ramos et al., 2017. Design, in silico studies, synthesis and in vitro evaluation of oseltamivir derivatives as inhibitors of neuraminidase from influenza A virus H1N1. Eur. J. Med. Chem., 128: 154-167.
    CrossRef  |  Direct Link  |  

  18. Julia, J., C.F.F. Jimena, F.G.E. Dalet, T.F.J. Guadalupe and S.U.M. Antonio, 2017. Scope of lipid nanoparticles in neuroscience: Impact on the treatment of neurodegenerative diseases. Curr. Pharmaceut. Des., 23: 3120-3133.
    CrossRef  |  Direct Link  |  

  19. Garcia-Avila, A.K., E.D. Farfan-Garcia, J.A. Guevara-Salazar, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2017. Scope of translational medicine in developing boron-containing compounds for therapeutics. World J. Transl. Med., 6: 1-9.
    CrossRef  |  Direct Link  |  

  20. Garrido-Acosta, O., S.E. Meza-Toledo, L. Anguiano-Robledo, M.A. Soriano-Ursua, J. Correa-Basurto, A. Davood and G. Chamorro-Cevallos, 2016. Anticonvulsant and toxicological evaluation of parafluorinated/chlorinated derivatives of 3-hydroxy-3-ethyl-3-phenylpropionamide. BioMed Res. Int., Vol. 2016. 10.1155/2016/3978010.
    CrossRef  |  Direct Link  |  

  21. Farfan-Garcia, E.D., N.T. Castillo-Mendieta, F.J. Cipres-Flores, I.I. Padilla-Martinez, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2016. Current data regarding the structure-toxicity relationship of boron-containing compounds. Toxicol. Lett., 258: 115-125.
    CrossRef  |  Direct Link  |  

  22. Farfan-Garcia, E.D., M. Perez-Rodriguez, C. Espinosa-Garcia, N.T. Castillo-Mendieta and M. Maldonado-Castro et al., 2016. Disruption of motor behavior and injury to the CNS induced by 3-thienylboronic acid in mice. Toxicol. Applied Pharmacol., 307: 130-137.
    CrossRef  |  Direct Link  |  

  23. Soriano-Ursua, M.A., J.G. Trujillo-Ferrara, J.A. Arias-Montano and R. Villalobos-Molina, 2015. Insights into a defined secondary binding region on β-adrenoceptors and putative roles in ligand binding and drug design. MedChemComm, 6: 991-1002.
    CrossRef  |  Direct Link  |  

  24. Soriano-Ursua, M.A., J.A. Arias-Montano, J. Correa-Basurto, C.F. Hernandez-Martinez and Y. Lopez-Cabrera et al., 2015. Insights on the role of boron containing moieties in the design of new potent and efficient agonists targeting the β2 adrenoceptor. Bioorg. Med. Chem. Lett., 25: 820-825.
    CrossRef  |  Direct Link  |  

  25. Mendez, J.P., J.C. Zenteno, A. Coronel, M.A. Soriano-Ursua and E.Y. Valencia-Villalvazo et al., 2015. Triallelic digenic mutation in the prokineticin 2 and GNRH receptor genes in two brothers with normosmic congenital hypogonadotropic hypogonadism. Endocr. Res., 40: 166-171.
    CrossRef  |  Direct Link  |  

  26. Madrigal-Santillan, E., M. Bautista, J.A. Gayosso-De-Lucio, Y. Reyes-Rosales and A. Posadas-Mondragon et al., 2015. Hepatoprotective effect of Geranium schiedeanum against ethanol toxicity during liver regeneration. World J. Gastroenterol., 21: 7718-7729.
    CrossRef  |  PubMed  |  Direct Link  |  

  27. Soriano-Ursua, M.A., E.D. Farfan-Garcia, Y. Lopez-Cabrera, E. Querejeta and J.G. Trujillo-Ferrara, 2014. Boron-containing acids: Preliminary evaluation of acute toxicity and access to the brain determined by Raman scattering spectroscopy. Neurotoxicology, 40: 8-15.
    CrossRef  |  

  28. Soriano-Ursua, M.A., B.C. Das and J.G. Trujillo-Ferrara, 2014. Boron-containing compounds: Chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy. Expert Opin. Therapeut. Patents, 24: 485-500.
    CrossRef  |  Direct Link  |  

  29. Segura-Cabrera, A., C.A. Garcia-Perez, F.J. Cipres-Flores, R.I. Cuevas-Hernandez, J.G. Trujillo-Ferrara, J. Correa-Basurto and M.A. Soriano-Ursua, 2014. Molecular dynamics simulations to explore the active/inactive conformers of guinea pig β2 adrenoceptor for the selective design of agonists or antagonists. Mol. Simul., 40: 1244-1254.
    CrossRef  |  Direct Link  |  

  30. Ramirez-San Juan, E., M.A. Soriano-Ursua, J. Espinosa-Raya, J. Correa-Basurto and J.G. Trujillo-Ferrara et al., 2014. Anticonvulsant effects of bis-1, 4-dihydropyridines and the probable role of L-type calcium channels suggested by docking simulations. Med. Chem. Res., 23: 5149-5159.
    CrossRef  |  Direct Link  |  

  31. Soriano-Ursua, M.A., J.G. Trujillo-Ferrara, J. Correa-Basurto and S. Vilar, 2013. Recent structural advances of β1 and β2 adrenoceptors yield keys for ligand recognition and drug design. J. Med. Chem., 56: 8207-8223.
    CrossRef  |  

  32. Soriano-Ursua, M.A., E.D. Farfan-Garcia and J.G. Trujillo-Ferrara, 2013. Notable advances in medicine from the structural biology of catecholamine-receptors. Acta Med. Politecnica, 1: 17-22.

  33. Soriano-Ursua, M.A., D. McNaught-Flores, J. Correa-Basurto, J.A. Arias-Montano, J.G. Trujillo-Ferrara, 2013. Histamine modulates isoproterenol efficacy at the β2 adrenoceptor: Inferences regarding allosteric modulation by imidazole-containing compounds. Biochem. Physiol., Vol. 2. 10.4172/2168-9652.1000114.
    CrossRef  |  

  34. Martinez-Ramos, F., Y. Fonseca-Sabater, M.A. Soriano-Ursua, E. Torres and M.C. Rosales-Hernandez et al., 2013. O-Alkylselenenylated benzoic acid accesses several sites in serum albumin according to fluorescence studies, Raman spectroscopy and theoretical simulations. Protein Pept. Lett., 20: 705-714.
    Direct Link  |  

  35. Farfan-Garcia, E.D., J.G. Trujillo-Ferrara, M.C. Castillo-Hernandez, C.H. Guerra-Araiza and M.A. Soriano-Ursua, 2013. Insights into the structural biology of GPCRs impacts drug design for CNS neurodegenerative processes. Neural. Regene. Res., 8: 2290-2302.

  36. Castro, J.J., J.P. Mendez, R.M. Coral-Vazquez, M.A. Soriano-Ursua and P. Damian-Matsumura et al., 2013. In vitro and molecular modeling analysis of two mutant desert hedgehog proteins associated with 46,XY gonadal dysgenesis. DNA Cell Biol., 32: 524-530.
    CrossRef  |  Direct Link  |  

  37. Soriano-Ursua, M.A., D.A. McNaught-Flores, G. Nieto-Alamilla, A. Segura-Cabrera, J. Correa-Basurto, J.A. Arias-Montano and J.G. Trujillo-Ferrara, 2012. Cell-based and in-silico studies on the high intrinsic activity of two boron-containing salbutamol derivatives at the human β₂-adrenoceptor. Bioorg. Med. Chem., 20: 933-941.
    CrossRef  |  

  38. Amezcua-Gutierrez, M.A., F.J. Cipres-Flores, J.G. Trujillo-Ferrara and M.A. Soriano-Ursua, 2012. Clinical implications of recent insights into the structural biology of β₂ adrenoceptor. Curr. Drug Targets, 13: 1336-1346.
    CrossRef  |  

  39. Soriano-Ursua, M.A., T. Mancilla-Percino, J. Correa-Basurto, E. Querejeta and J.G. Trujillo-Ferrara, 2011. Give boron a chance: Boron containing compounds reach ionotropic and metabotropic transmembrane receptors. Mini Rev. Med. Chem., 11: 1031-1038.
    Direct Link  |  

  40. Soriano-Ursua, M.A., J.O. Ocampo-Lopez, K. Ocampo-Mendoza, J.G. Trujillo-Ferrara and J. Correa-Basurto, 2011. Theoretical study of 3-D molecular similarity and ligand binding modes of orthologous human and rat D2 dopamine receptors. Comput. Biol. Med., 41: 537-545.
    CrossRef  |  

  41. Soriano-Ursua, M.A., J. Correa-Basurto, J.G. Trujillo-Ferrara and A.J. Kaumann, 2011. Homology model and docking studies on porcine β2 adrenoceptor: Description of two binding sites. J. Mol. Model., 17: 2525-2538.
    CrossRef  |  

  42. Lopez-Hernandez, L.B., D. van Heusden, M.A. Soriano-Ursua, L. Figuera-Villanueva and N.A. Vazquez-Cardenas et al., 2011. Genotype-phenotype discordance in a Duchenne muscular dystrophy patient due to a novel mutation: Insights into the shock absorber function of dystrophin. Rev. Neurol., 52: 720-724.
    Direct Link  |  

  43. Soriano-Ursua, M.A., J.G. Trujillo-Ferrara, J. Alvarez-Cedillo and J. Correa-Basurto, 2010. Docking studies on a refined human β2 adrenoceptor model yield theoretical affinity values in function with experimental values for R-ligands but not for S-antagonists. J. Mol. Model., 16: 401-409.
    CrossRef  |  

  44. Soriano-Ursua, M.A., J.G. Trujillo-Ferrara and J. Correa-Basurto, 2010. Scope and difficulty in generating theoretical insights regarding ligand recognition and activation of the β2 adrenergic receptor. J. Med. Chem., 53: 923-932.
    CrossRef  |  

  45. Soriano-Ursua, M.A., J. Correa-Basurtoa, I. Valencia-Hernandez, M.A. Amezcua-Gutierrez, I.I. Padilla-Martinez, J.G. Trujillo-Ferrara, 2010. Design, synthesis and in vitro evaluation of (R)-4-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenyl hydrogen phenylboronate: A novel salbutamol derivative with high intrinsic efficacy on the β2 adrenoceptor. Bioorg. Med. Chem. Lett., 20: 5623-5629.
    CrossRef  |  

  46. Soriano-Ursua, M.A., J. Correa-Basurto, J. Romero-Huerta, O. Elizalde-Solis, L.A. Galicia-Luna and J.G. Trujillo-Ferrara, 2010. Pharmacokinetic parameters and a theoretical study about metabolism of BR-AEA (a salbutamol derivative) in rabbit. J. Enzyme Inhibition Med. Chem., 25: 340-346.
    CrossRef  |  Direct Link  |  

  47. Soriano-Ursua, M.A., J.G. Trujillo-Ferrara and J. Correa-Basurto, 2009. Homology modeling and Flex-ligand docking studies on the guinea pig β2 adrenoceptor: Structural and experimental similarities/differences with the human β2. J. Mol. Model., 15: 1203-1211.
    CrossRef  |  

  48. Soriano-Ursua, M.A., I. Valencia-Hernandez, M.G. Arellano-Mendoza, J. Correa-Basurto and J.G. Trujillo-Ferrara, 2009. Synthesis, pharmacological and in silico evaluation of 1-(4-di-hydroxy-3, 5-dioxa-4-borabicyclo [4.4. 0] deca-7, 9, 11-trien-9-yl)-2-(tert-butylamino) etanol, a compound designed to act as a β2 adrenoceptor agonist. Eur. J. Med. Chem., 44: 2840-2846.
    CrossRef  |  Direct Link  |  
Member since January, 2014