Dr. Lycia de Brito Gitirana

Research Scientist
Federal University of Rio de Janeiro, Brazil

Highest Degree
Ph.D. in Biology from Heidelberg University, Germany

My URL
https://livedna.org/55.15145

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Area of Interest:

Biomedical Sciences
Molecular Biology
Nanotechnology
Nanomedicine
Cell Biology

Selected Publications

  1. Da Silva Abe, A.S.F., E. Ricci-Junior, M.T.L.C. Branco and L.D.B. Gitirana, 2016. Action of the anti-tumoral zinc(II) phthalocyanine in solution or encapsulated into nanoparticles of poly-ε-caprolactone internalized by peritoneal macrophages. Adv. Nat. Sci.: Nanosci. Nanotechnol., Vol. 7. 10.1088/2043-6262/7/3/035017.
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  2. Valle, G.M., L.P. Cinelli, A.R. Todeschini, L de Brito-Gitirana, A.C.E.S. Vilela-Silva and P.A.S. Mourao, 2015. Sperm and egg jelly coat from sea urchin Lytechinus variegates collected in Rio de Janeiro contain distinct Sialic acid-rich polysaccharides. Braz. Arch. Biol. Technol., 58: 617-627.
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  3. Machado-Santos, C., A.A. Pelli-Martins, M. Abidu-Figueiredo and L. de Brito-Gitirana, 2014. Histochemical and immunohistochemical analysis of the stomach of Rhinella icterica (Anura, Bufonidae). J. Histol. 10.1155/2014/872795.
    CrossRef  |  Direct Link  |  

  4. Ferreira, T.S., M. Lanzetti, M.V. Barroso, C.R. Rueff-Barroso and C.F. Benjamim et al., 2014. Oxidative stress and inflammation are differentially affected by atorvastatin, pravastatin, rosuvastatin and simvastatin on lungs from mice exposed to cigarette smoke. Inflammation, 37: 1355-1365.
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  5. Felsemburgh, F.A., J. Siqueira-Francisco, M.T.L.C. Branco, M.V.M. de Almeida, A. Ferreira-Pereira and L. de Brito-Gitirana, 2014. The parotoid gland secretion of bufonids inhibits the activity of the multidrug resistance target Pdr5p from yeast plasma membranes. Annu. Res. Rev. Biol., 4: 378-391.
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  6. Santis, A.K., Z.M.F. de Freitas, E. Ricci-Junior, L. de Brito-Gitirana, L.B. Fonseca and E.P. Santos, 2013. Nifedipine in semi-solid formulations for topical use in peripheral vascular disease: Preparation, characterization and permeation assay. Drug Dev. Ind. Pharm., 39: 1098-1106.
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  7. Melo, A.C., S.S. Valenca, L.B. Gitirana, J.C. Santos and M.L. Ribeiro et al., 2013. Redox markers and inflammation are differentially affected by atorvastatin, pravastatin or simvastatin administered before endotoxin-induced acute lung injury. Int. Immunopharmacol., 17: 57-64.
    CrossRef  |  Direct Link  |  

  8. Pelli-Martins, A.A., C. Machado-Santos, A. Sales and L. de Brito-Gitirana, 2012. Histochemical, immunohistochemical, and ultrastructural observations of the esophagus morphology of Rinella icterica (Anuran, Bufonidae). Acta Zoologica, 93: 373-380.
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  9. Monteiro, M.S.S.B, R.A. Ozzetti, A.L. Vergnanini, L.B. Gitirana and N.M. Volpato et al., 2012. Evaluation of octyl p-methoxycinnamate included in liposomes and cyclodextrins in anti-solar preparations: Preparations, characterizations and in vitro penetration studies. Int. J. Nanomedicine, 7: 3045-3058.

  10. De Brito-Gitirana, L. and T. Silva-Soares, 2012. Chromomycosis in Rhinella icterica. Open Zool. J., 5: 38-41.
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  11. Da Volta Soares, M., M.R. Oliveira, E.P. dos Santos, L. de Brito Gitirana, G.M. Barbosa, C.H. Quaresma and E. Ricci-Junior, 2011. Nanostructured delivery system for zinc phthalocyanine: Preparation, characterization and phototoxicity study against human lung adenocarcinoma A549 cells. Int. J. Nanomed., 6: 227-238.
    CrossRef  |  PubMed  |  Direct Link  |  

  12. Da Silva, E.R., Z.M.F. de Freitas, L. de Brito Gitirana and E. Ricci-Junior, 2011. Improving the topical delivery of zinc phthalocyanine using oleic acid as a penetration enhancer: In vitro permeation and retention. Drug Dev. Ind. Pharm., 37: 569-575.
    CrossRef  |  Direct Link  |  

  13. Pelli, A.A., L.P. Cinelli, P.A.S. Mourao and L. de Brito-Gitirana, 2010. Glycosaminoglycans and glycoconjugates in the adult anuran integument (Lithobates catesbeianus). Micron, 41: 660-665.
    CrossRef  |  Direct Link  |  

  14. Felsemburgh, F.A., P.G. de Almeida, S.P. de Carvalho-e-Silva and L. de Brito-Gitirana, 2009. Microscopical methods promote the understanding of the integument biology of Rhinella ornata. Micron, 40: 198-205.
    CrossRef  |  Direct Link  |  

  15. De Brito-Gitirana, L., F.A. Felsemburgh, S.P. de Carvalho e Silva and P.G. de Almeida, 2009. Is the chytrid fungus really responsible for amphibian decline? Open Zool. J., 2: 49-52.
    CrossRef  |  Direct Link  |  

  16. De Abreu Manso, P.P., L. de Brito-Gitirana and M. Pelajo-Machado, 2009. Localization of hematopoietic cells in the bullfrog (Lithobates catesbeianus). Cell Tissue Res., 337: 301-312.
    CrossRef  |  Direct Link  |  

  17. Goncalves, V.F. and L. de Brito-Gitirana, 2008. Structure of the sexually dimorphic gland of Cycloramphus fuliginosus (Amphibia, Anura, Cycloramphidae). Micron, 39: 32-39.
    CrossRef  |  Direct Link  |  

  18. Pelli, A.A., R.A. Azevedo, L.P. Cinelli, P.A.S. Mourao and L. de Brito-Gitirana, 2007. Dermatan sulfate is the major metachromatic glycosaminoglycan in the integument of the anuran Bufo ictericus. Comp. Biochem. Physiol. Part B: Biochem. Mol. Biol., 146: 160-165.
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  19. Felsemburgh, F.A., S.P. Carvalho-e-Silva and L. de Brito-Gitirana, 2007. Morphological characterization of the anuran integument of the Proceratophrys and Odontophrynus genera (Amphibia, Anuran, Leptodactylidae). Micron, 38: 439-445.
    CrossRef  |  Direct Link  |  

  20. De Brito Gitirana, L., R.A. Azevedo and A.A. Pelli, 2007. Expression pattern of glycoconjugates in the integument of Bufo ictericus (Anuran, Bufonidae): Biochemical and histochemical (lectin) profiles. Tissue Cell, 39: 415-421.
    CrossRef  |  Direct Link  |  

  21. De Almeida, P.G., F.A. Felsemburg, R.A. Azevedo and L. de Brito-Gitirana, 2007. Morphological re-evaluation of the parotoid glands of Bufo ictericus (Amphibia, Anura, Bufonidae). Contrib. Zool., 76: 145-152.
    Direct Link  |  

  22. Azevedo, R.A., H.F. Carvalho and L. de Brito-Gitirana, 2007. Hyaluronan in the epidermal and the dermal extracellular matrix: Its role in cutaneous hydric balance and integrity of anuran integument. Micron, 38: 607-610.
    CrossRef  |  PubMed  |  Direct Link  |  

  23. Farias, C.F., R.A. Azevedo and L. Brito-Gitirana, 2006. Expression pattern of glycoconjugates in the Bidderian and ovarian follicles of the Brazilian toad Bufo ictericus analyzed by lectin histochemistry. Braz. J. Biol., 66: 45-51.
    CrossRef  |  Direct Link  |  

  24. Azevedo, R.A., A.S. de Jesus Santana and L. de Brito-Gitirana, 2006. Dermal collagen organization in Bufo ictericus and in Rana catesbeiana integument (Anuran, Amphibian) under the evaluation of laser confocal microscopy. Micron, 37: 223-228.
    CrossRef  |  Direct Link  |  

  25. De Jesus Santana, A.S., S.P. de Carvalho-e-Silva and L. de Brito-Gitirana, 2005. Structural aspects of an unusual choroidal polarized hyaline cartilage in the eyeball of Bufo ictericus and Rana catesbeiana (Amphibia, Anura): Morphological and physiological significance. Micron, 36: 89-93.
    CrossRef  |  Direct Link  |  

  26. De Brito-Gitirana, L. and R.A. Azevedo, 2005. Morphology of Bufo ictericus integument (Amphibia, Bufonidae). Micron, 36: 532-538.
    CrossRef  |  PubMed  |  Direct Link  |  

  27. Babinski, M.A., L. de Brito-Gitirana, M.A. Chagas, M. Abidu-Figueiredo, W.S. Costa and F.J.B. Sampaio, 2005. Immunohistochemical analysis of smooth muscle cells and volumetric density of the elastic system fibers of wild boar (Sus scrofa) penis. Anim. Reprod. Sci., 86: 317-328.
    CrossRef  |  Direct Link  |  

  28. Azevedo, R.A., A.A. Pelli, A. Ferreira-Pereira, A.S. de Jesus Santana, F. Felsemburgh and L. de Brito-Gitirana, 2005. Structural aspects of the Eberth-Katschenko layer of Bufo ictericus integument: Histochemical characterization and biochemical analysis of the cutaneous calcium (Amphibian, Bufonidae). Micron, 36: 61-65.
    CrossRef  |  Direct Link  |  

  29. Farias, C.F., L. de Brito-Gitirana and S.P. Carvalho-e-Silva, 2004. Bidder's organ in the female of Bufo ictericus: Morphological characterization. Contrib. Zool., 73: 317-319.
    Direct Link  |  

  30. Neves, C.A., L.B. Gitirana and J.E. Serrao, 2003. Ultrastructural study of the metamorphosis in the midgut of Melipona quadrifasciata anthidioides (Apidae, Meliponini) worker. Sociobiology, 41: 443-459.

  31. Neves, C.A., L. de Brito-Gitirana and J.E. Serrao, 2003. Ultrastructure of the midgut endocrine cells in Melipona quadrifasciata anthidioides (Hymenoptera, Apidae). Braz. J. Biol., 63: 683-690.
    CrossRef  |  Direct Link  |  

  32. Manaf, P., L. de Brito-Gitirana and E.S. Oliveira, 2003. Evidence of chemical communication in the spiny rat Trinomys yonenagae (Echimyidae): Anal scent gland and social interactions. Can. J. Zool., 81: 1138-1143.
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  33. Vianna, V., C. Takiya and L. de Brito-Gitirana, 2002. Histopathologic analysis of hamster hepatocytes submitted to experimental infection with Leishmania donovani. Parasitol. Res., 88: 829-836.
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  34. Neves, C.A., L.L. Bhering, J.E. Serrao and L.B. Gitirana, 2002. FMRFamide-like midgut endocrine cells during the metamorphosis in Melipona quadrifasciata anthidioides (Hymenoptera, Apidae). Micron, 33: 453-460.
    CrossRef  |  Direct Link  |  

  35. Farias, C.F., S.P. Carvalho-e-Silva and L. de Brito-Gitirana, 2002. Bidder's organ of Bufo ictericus: A light and electron microscopy analysis. Micron, 33: 673-679.
    CrossRef  |  Direct Link  |  

  36. De Brito-Gitirana, L. and V. Storch, 2002. Temperature induced alterations in the liver of wall lizard (Hemidactylus frenatus): Morphological and biochemical parameters. Micron, 33: 667-672.
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  37. Maia, R.S., L. de Brito-Gitirana, L. and V.S. Braz, 2001. Contribution to histological characterization of the OS penis in mongred dogs. Indian J. Vet. Anat., 13: 53-57.

  38. De Brito-Gitirana, L. and N.C.O. Miguel, 2000. Electron microscopical investigation on aldrin-induced hepatocyte pathology in Rana catesbeiana, with special emphasis on peroxisomes. Exp. Toxicol. Pathol., 52: 339-347.
    CrossRef  |  Direct Link  |  

  39. De Brito-Gitirana, L. and A.V. Trindade, 2000. Direct blue staining plus polarization microscopy: An alternative dye for polarization method for collagen detection in tissue sections. J. Histotechnol., 23: 347-349.
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  40. Trindade, A.V., A.P.S. Brandao, A.F. de Sousa, C.F. Farias and L. de Brito-Gitirana, 1998. Enhancement of the paraldehyde-Fuchsin staining. J. Histotechnol., 21: 147-150.
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  41. Francescutti-Murad, L.H. and L. de Brito-Gitirana, 1998. Ultrastructural and histochemical study of collagen fibres types I and III in the venom gland of Bothrops jararaca during secretory cycle. Tissue Cell, 30: 293-303.
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  42. De Brito-Gitirana, L., C.F. Farias, A.P.S. Brandao, V. Storch and J.M.T. da Cunha, 1996. Ultrastructural aspects of Merkel cells in fish (Arius spixii) integument. Braz. J. Morphol. Sci., 13: 15-18.

  43. De Brito-Gitirana, L., 1988. The fine structure of the fat-storing cell (Ito cell) in the liver of some reptiles. Zeitschrift Mikroskopisch-Anatomische Forschung, 102: 143-149.
    PubMed  |  Direct Link  |  

  44. De Brito-Gitirana, L. and V. Storch, 1988. The ultrastructure of the hepatocytes of the Brazilian land tortoise (Testudo carbonaria, Spix) during thermal adaptation. Zoologischer Anzeiger, 202: 1-7.

  45. De Brito-Gitirana, L., 1987. The first report of the occurrence of cilium in fat-storing cells in the reptilian liver (Eumeces algeriensis, Daudin 1802). Archivum Histologicum Japonicum, 50: 359-361.
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  46. De Brito-Gitirana, L., 1987. Histological, histochemical and ultrastructural study of the hepatic pigment of the frog, Leptodactylus ocellatus, L. Zeitschrift Mikroskopisch-Anatomische Forschung, 101: 331-338.
    PubMed  |  
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