Dr. Chin Eng Ong

Researcher
Monash University Malaysia Campus, Malaysia


Highest Degree
GCP in Clinical trials from International Medical University, Malaysia

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Area of Interest:

Pharmacology and Toxicology
Drug Metabolism
Cytochrome P450
Pharmacogenetics
Drug-Herb Interaction

Selected Publications

  1. Pan, Y., B.A. Abd-Rashid, Z. Ismail, R. Ismail and J.W. Mak et al., 2011. In vitro modulatory effects of Andrographis paniculata, Centella asiatica and Orthosiphon stamineus on cytochrome P450 2C19 (CYP2C19). J. Ethnopharmacol., 133: 881-887.
    CrossRef  |  PubMed  |  Direct Link  |  

  2. Tiong, K.H., B.C. Yiap, E.L. Tan, R. Ismail and C.E. Ong, 2010. In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity. Xenobiotica, 40: 458-466.
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  3. Tiong, K.H., B.C. Yiap, E.L. Tan, R. Ismail and C.E. Ong, 2010. Functional characterization of cytochrome P450 2A6 allelic variants CYP2A6*15, CYP2A6*16, CYP2A6*21, and CYP2A6*22. Drug Metabolism Disposition, 38: 745-751.
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  4. Pan, Y., B.A. Abd-Rashid, Z. Ismail, R. Ismail and J.W. Mak et al., 2010. In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica. J. Ethnopharmacol., 130: 275-283.
    CrossRef  |  PubMed  |  Direct Link  |  

  5. Singh, R., J.G. Ting, Y. Pan, L.K. Teh, R. Ismail and C.E. Ong, 2008. Functional role of Ile264 in CYP2C8: Mutations affect haem incorporation and catalytic activity. Drug Metabolism Pharmacokinetics, 23: 165-174.
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  6. Ong, C.E., Y. Pan, K.H. Tiong, B.C. Yiap, E.L. Tan, P. Pook and J.W. Mak, 2008. Pharmacogenomics in drug therapy and interaction: The role of cytochrome P450. Int. J. Sci. Med. Educ., 2: S6-S10.
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