Dr. Vikneswaran Murugaiyah

Lecturer
Universiti Sains Malaysia, Malaysia

Highest Degree
Ph.D. in Pharmaceutical Chemistry from Universiti Sains Malaysia, Malaysia

My URL
https://livedna.org/60.20774

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Area of Interest:

Pharmacology and Toxicology
Hormetic Phytochemicals
Neurodegenerative
Lipid Disorders
Biochemistry

Selected Publications

  1. Yeong, K.Y., W.L. Liew, V. Murugaiyah, C.W. Ang, H. Osman and S.C. Tan, 2017. Ethyl nitrobenzoate: A novel scaffold for cholinesterase inhibition. Biorganic Chem., 70: 27-33.
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  2. Revadigar, V., M.A. Al-Mansoub, M. Asif, M.R. Hamdan, A.M.S.A. Majid, M.Z. Asmawi and V. Murugaiyah, 2017. Anti-oxidative and cytotoxic attributes of phenolic rich ethanol extract of Musa balbisiana Colla inflorescence. J. Applied Pharm. Sci., 7: 103-110.
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  3. Mostafa, H., A.M. Amin, C.H. Teh, V. Murugaiyah, N.H. Arif and B. Ibrahim, 2017. Plasma metabolic biomarkers for discriminating individuals with alcohol use disorders from social drinkers and alcohol-naive subjects. J. Substance Abuse Treat., 77: 1-5.
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  4. Mostafa, H., A.M. Amin, C.H. Teh, V. Murugaiyah, N.H. Arif and B. Ibrahim, 2017. Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence. Songklanakarin J. Sci. Technol., 39: 153-162.
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  5. Lakshmipriya, T., S.C. Gopinath, U. Hashim and V. Murugaiyah, 2017. Multi-analyte validation in heterogeneous solution by ELISA. Int. J. Biol. Macromol., 105: 796-800.
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  6. Kunasundari, B., C.R. Arza, F.H.J. Maurer, V. Murugaiyah, G. Kaur and K. Sudesh, 2017. Biological recovery and properties of poly(3-hydroxybutyrate) from Cupriavidus necator H16. Sep. Purif. Technol., 172: 1-6.
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  7. Ebrahimi, F., B. Ibrahim, C.H. Teh, V. Murugaiyah and K.L. Chan, 2017. NMR_based plasma metabolomics discrimination for male fertility assessment of rats treated with Eurycoma longifolia extracts. Syst. Biol. Reprod. Med., 63: 179-191.

  8. Ebrahimi, F., B. Ibrahim, C.H. Teh, V. Murugaiyah and K.L. Chan, 2017. 1HNMR-based discriminatory analysis of Eurycoma longifolia from different locations and establishing a profile for primary metabolites identification and quassinoids quantification. Planta Med., 83: 172-182.
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  9. Christapher, P.V., S. Parasuraman, M.Z. Asmawi and V. Murugaiyah, 2017. Acute and subchronic toxicity studies of methanol extract of Polygonum minus leaves in Sprague Dawley rats. Regul. Toxicol. Pharmacol., 86: 33-41.
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  10. Basiri, A., B.M.A. Razik, M.O. Ezzat, Y. Kia and R.S. Kumar et al., 2017. Synthesis and cholinesterase inhibitory activity study of new piperidone grafted spiropyrrolidines. Bioorganic Chem., 75: 210-216.
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  11. Abubakar, S., V. Murugaiyah, C.H. Teh and K.L. Chan, 2017. Structural reassignment of koetjapic acid following X-ray crystallography and NMR spectroscopy. Nat. Prod. Commun., 12: 1017-1020.

  12. Vigneswari, S., V. Murugaiyah, G. Kaur, H.P.S. Abdul Khalil and A.A. Amirul, 2016. Simultaneous dual syringe electrospinning system using benign solvent to fabricate nanfibrous P(3HB-co-4HB)/collagen peptides construct as potential leave-on wound dressing. Mater. Sci. Eng. C, 66: 147-155.

  13. Vigneswari, S., V. Murugaiyah, G. Kaur, H.A. Khalil and A.A. Amirul, 2016. Biomacromolecule immobilization: Grafting of fish-scale collagen peptides onto aminolyzed P (3HB-co-4HB) scaffolds as a potential wound dressing. Biomed. Mater., Vol. 11. .
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  14. Sukumarapillai, D.K., K.Y. Khaw, Y. Kia, V. Murugaiyah and S.K. Iyer, 2016. Design, synthesis and cholinesterase inhibition evaluation study of fluorescent N-benzylpiperidine-4-one derivatives. Med. Chem. Res., 25: 1705-1715.

  15. Saghir, S.A.M., A. Sadikun, F.S.R. Al-Suede, A.M.S.A. Majid and V. Murugaiyah, 2016. Antihyperlipidemic, antioxidant and cytotoxic activities of methanolic and aqueous extracts of different parts of star fruit. Curr. Pharm. Biotechnol., 17: 915-925.
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  16. Rajan, V.P., S. Gunasekaran, S. Ramanathan, V. Murugaiyah, M.W. Samsudin and L.B. Din, 2016. Biological activities if four Parmotrema species of Malaysian origin and their chemical constituents. J. Applied Pharm. Sci., 6: 36-43.

  17. Othman, W.N.N.W., S.Y. Liew, K.Y. Khaw, V. Murugaiyah, M. Litaudon and K. Awang, 2016. Cholinesterase inhibitory activity of isoquinoline alkaloids from three Cryptocarya species (Lauraceae). Bioorganic Med. Chem., 24: 4464-4469.
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  18. Mousavi, L., R.M. Salleh, V. Murugaiyah and M.Z. Asmawi, 2016. Hypoglycemic and anti-hyperglycemic study of Ocimum tenuiflorum L. leaves extract in normal and streptozotocin-induced diabetic rats. Asian Pac. J. Trop. Biomed., 6: 1029-1036.
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  19. Mousavi, L., R.M. Salleh, V. Murugaiyah and M.Z. Asmawi, 2016. Anti-diabetic chemical constituents isolated from traditional medicinal plants. J. Global Trends Pharm. Sci., 7: 3074-3083.

  20. Mostafa, H., A.M. Amin, C.H. The, V. Murugaiyah, N.H. Arif and B. Ibrahim, 2016. Metabolic phenotyping of urine for discriminating alcohol-dependent from social drinkers and alcohol-naïve subjects. Drugs Alcohol Dependence, 169: 80-84.

  21. Gunasekaran, S., V.P. Rajan, S. Ramanathan, V. Murugaiyah, M.W. Samsudin and L. Din, 2016. Antibacterial and antioxidant activity of lichens Usnea rubrotincta, Ramalina dumeticola, Cladonia verticillata and their chemical constituents. Malaysian J. Anal. Sci., 20: 1-13.
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  22. Ebrahimi, F., B. Ibrahim, C.H. Teh, V. Murugaiyah and K.L. Chan, 2016. Urinary NMR-based metabolomics analysis of rats possessing variable sperm-count following orally administered Eurycoma longifolia extracts of different quassinoid levels. J. Ethnopharmacol., 182: 80-89.

  23. Christapher, P.V., S. Parasuraman, P.V. Raj, S.A.M. Saghir, M.Z. Asmawi and M. Vikneswaran, 2016. Influence of extracting solvent on pharmacological activity and cytotoxicity of Polygonum minus, a commonly consumed herb in Southeast Asia. Pharmacogn. Magaz., 12: S424-S430.
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  24. Chear, N.J.Y., K.Y. Khaw, V. Murugaiyah and C.S. Lai, 2016. Cholinesterase inhibitory activity and chemical constituents of Stenochlaena palustris fronds at two different stages of maturity. J. Food Drug Anal., 24: 358-366.
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  25. Bendran, A.R., V. Murugaiyah and S. Ramanathan, 2016. Review on murine models available for dengue vaccine development. Indian J. Nat. Prod. Resour., 7: 201-206.

  26. Asif, M., A.H.S. Yehya, M.A. Al-Mansoub, V. Revadigar and M.O. Ezzat et al., 2016. Anticancer attributes of Illicium verum essential oils against colon cancer. S. Afr. J. Bot., 103: 156-161.
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  27. Abd Razik, B.M., H. Osman, M.O. Ezzat, A. Basiri, A. Salhin, Y. Kia and V. Murugaiyah, 2016. Efficient synthesis and discovery of Schiff bases as potent cholinesterase inhibitors. Med. Chem., 12: 527-536.
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  28. Ramanathan, S., S. Parthasarathy, V. Murugaiyah, E. Magosso, S.C. Tan and S.M. Mansor, 2015. Understanding the physicochemical properties of mitragynine, a principal alkaloid of Mitragyna speciosa, for preclinical evaluation. Molecules, 20: 4915-4927.
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  29. Murugaiyah, V. and M.P. Mattson, 2015. Neurohormetic phytochemicals: An evolutionary-bioenergetic perspective. Neurochem. Int., 89: 271-280.

  30. Liew, S.K., K.Y. Khaw, V. Murugaiyah, C.Y. Looi and Y.L. Wong et al., 2015. Natural indole butyrylcholinesterase Inhibitors from Nauclea officinalis. Phytomedicine, 22: 45-48.

  31. Jamila, N., M. Khairuddean, K.K. Yeong, H. Osman and V. Murugaiyah, 2015. Cholinesterase inhibitory triterpenoids from the bark of Garcinia hombroniana. J. Enzyme Inhib. Med. Chem., 30: 133-139.
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  32. Jamila, N., K.K. Khaw, V. Murugaiyah, A. Khan and N. Khan et al., 2015. Molecular docking studies and in vitro cholinesterase enzymes inhibitory activites of chemical constituents of Garcinia hombroniana. Nat. Prod. Res., 29: 86-90.

  33. Ghalib, R.M., R. Hashim, S.H. Mehdi, M.F.C.G. da Silva and O. Sulaiman et al., 2015. Synthesis, crystal structure and cholinesterase enzymes inhibitory activities of new pyridine alkaloid derivative. Asian J. Chem., 27: 4092-4096.

  34. Fadaeinasab, M., A. Basiri, Y. Kia, H. Karimian, H.M. Ali and V. Murugaiyah, 2015. New indole alkaloids from the bark of Rauvolfia reflexa and their cholinesterase inhibitory activity. Cell. Physiol. Biochem., 37: 1997-2011.
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  35. Christapher, P.V., T.Y. Xin, C.F. Kiun, L.C. Leng and N.G. Fu et al., 2015. Evaluation of analgesic, anti-inflammatory, antipyretic and antiulcer effect of aqueous and methanol extracts of leaves of Polygonum minus Huds.(Polygonaceae) in rodents. Arch. Med. Health Sci., 3: 12-17.
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  36. Christapher, P.V., S. Parasuraman, J.M.A. Christina, M.Z. Asmawi and V. Murugaiyah, 2015. Review on Polygonum minus Huds, a commonly used food additive in Southeast Asia. Pharmacogn. Res., 7: 1-6.

  37. Cheng, L.C., V. Murugaiyah and K.L. Chan, 2015. In vitro xanthine oxidase inhibitory studies of Lippia nodiflora and isolated flavonoids and phenylethanoid glycosides as potential uric acid-lowering agents. Nat. Prod. Commun., 10: 945-948.
    PubMed  |  

  38. Cheng, L.C., V. Murugaiyah and K.L. Chan, 2015. Flavonoids and phenylethanoid glycosides from Lippia nodiflora as promising antihyperuricemic agents and elucidation of their mechanism of action. J. Ethnopharmacol., 176: 485-493.
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  39. Almansour, A.I., R.S. Kumar, N. Arumugam, A. Basiri and Y. Kia et al., 2015. A facile ionic liquid promoted synthesis, cholinesterase inhibitory activity and molecular modeling study of novel highly functionalized spiropyrrolidines. Molecules, 20: 2296-2309.
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  40. Wei, A.C., M.A. Ali, Y.K. Yoon, R. Ismail and T.S. Choon et al., 2014. Synthesis of highly functionalised dispiropyrrolidine derivatives as novel acetylcholinesterase inhibitors. Lett. Drug Des. Discov., 11: 156-161.
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  41. Tan, W.N., M. Khairuddean, K.C. Wong, K.Y. Khaw and V. Murugaiyah, 2014. New cholinesterase inhibitors from Garcinia atroviridis. Fitoterapia, 97: 261-267.

  42. Subramaniam, S., J. Sundarasekar, G. Sahgal and V. Murugaiyah, 2014. Comparative analysis of lycorine in wild plant and callus culture samples of Hymenocallis littoralis by HPLC-UV method. Scient. World J., Vol. 2014. 10.1155/2014/408306.
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  43. Sandrasagaran, U.M., S. Subramaniamand V. Murugaiyah, 2014. New perspective of Dendrobium crumenatum orchid for antimicrobial activity against selected pathogenic bacteria. Pak. J. Bot., 46: 719-724.
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  44. Saghir, S., V. Revadigar and V. Murugaiyah, 2014. Natural lipid lowering agents and their effect: An update. Eur. Food Res. Technol., 238: 705-725.

  45. Saeed, M.A.A., Y.M. Kuong, A. Sadikun, V. Murugaiyah, M.Z. Asmawi and Z. Ismail, 2014. Stability study of Gynura procumbens extracts using high performance liquid chromatography. J. Pharm. Res., 8: 822-827.
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  46. Revadigar, V., R.M. Ghalib, V. Murugaiyah, M.A. Embaby and A. Jawad et al., 2014. Enzyme Inhibitors Involved in the Treatment of Alzheimers Disease. In: Frontiers in Drug Design and Discovery, Atta-Ur-Rahman and ‎M.I. Choudhary (Eds.). Bentham Science Publishers, USA., ISBN: 978-1-60805-823-5, pp: 142-198.

  47. Mousavi, L., R.M. Salleh, V. Murugaiyah and M.T. Ong, 2014. Comparison of antimicrobial activity of different extract of Ocimum tenuiflorum L. leaf and stem. Annu. Res. Rev. Biol., 4: 3742-3750.

  48. Marimuthu, M.M., C.A. Aruldass, U.M. Sandrasagaran, S. Mohamad, S. Ramanathan, S.M. Mansor and V. Murugaiyah, 2014. Antimicrobial activity and phytochemical screening of various parts of Ixora coccinea. J. Med. Plant Res., 8: 423-429.
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  49. Koay, Y.H., A. Basiri, V. Murugaiyah and K.L. Chan, 2014. Isocorilagin, a cholinesterase inhibitor from Phyllanthus niruri. Nat. Prod. Commun., 9: 515-517.
    PubMed  |  

  50. Kia, Y., H. Osman, R.S. Kumar, V. Murugaiyah, A. Basiri, K.Y. Khaw and M.M. Rosli, 2014. An efficient ionic liquid mediated synthesis, cholinesterase inhibitory activity and molecular modeling study of novel piperidone embedded α,β-unsaturated ketones. Med. Chem., 10: 512-520.
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  51. Kia, Y., H. Osman, R.S. Kumar, A. Basiri and V. Murugaiyah, 2014. Synthesis and discovery of highly functionalized mono-and bis-spiro-pyrrolidines as potent cholinesterase enzyme inhibitors. Bioorganic Med. Chem. Lett., 24: 1815-1819.
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  52. Kia, Y., H. Osman, R.S. Kumar, A. Basiri and V. Murugaiyah, 2014. Ionic liquid mediated synthesis of mono- and bis-spirooxindole-hexahydropyrrolidines as cholinesterase enzymes inhibitors and their molecular docking studies. Bioorganic Med. Chem., 22: 1318-1328.

  53. Khaw, K.Y., S.B. Choi, S.C. Tan, H.A. Wahab, K.L. Chan and V. Murugaiyah, 2014. Prenylated xanthones from mangosteen as promising cholinesterase inhibitors and their molecular docking studies. Phytomedicine, 21: 1303-1309.
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  54. Kamilla, L., S. Ramanathan, S. Sasidharan, V. Murugaiyah and S.M. Mansor, 2014. Efficacy of Clitoria ternatea leaf extract against experimental aspergillosis. Int. J. Pharm. Pharm. Sci., 6: 514-516.

  55. Basiri, A., V. Murugaiyah, H. Osman, R.S. Kumar, Y. Kia, A. Hooda and R.B. Parsons, 2014. Cholinesterase inhibitory activity versus aromatic core multiplicity: A facile green synthesis and molecular docking study of novel piperidone embedded thiazolopyrimidines. Bioorganic Med. Chem., 22: 906-916.
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  56. Al‐Mansoub, M.A., M. Asmawi and V. Murugaiyah, 2014. Effect of extraction solvents and plant parts used on the antihyperlipidemic and antioxidant effects of Garcinia atroviridis: A comparative study. J. Sci. Food Agric., 94: 1552-1558.
    CrossRef  |  Direct Link  |  

  57. Abd Razik, B.M., H. Osman, A. Basiri, A. Salhin, Y. Kia, M.O. Ezzat and V. Murugaiyah, 2014. Ionic liquid mediated synthesis and molecular docking study of novel aromatic embedded Schiff bases as potent cholinesterase inhibitors. Bioorganic Chem., 57: 162-168.
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  58. Yoon, Y.K., M.A. Ali, A.C. Wei, T.S. Choon and K.Y. Khaw et al., 2013. Synthesis, characterization and molecular docking analysis of novel benzimidazole derivatives as cholinesterase inhibitors. Bioorganic Chem., 49: 33-39.
    Direct Link  |  

  59. Saghir, S.A.M., A. Sadikun, K.Y. Khaw and V. Murugaiyah, 2013. Star fruit (Averrhoa carambola L.): From traditional uses to pharmacological activities. Latin Am. Caribbean Bull. Med. Aromatic Plants, 12: 209-219.

  60. Ponnusamy, Y., N.J.Y. Chear, S. Ramanathan, V. Murugaiyah and C.S. Lai, 2013. Antioxidant and antibacterial properties of Malaysian ferns used traditionally against infection. J. Nat. Prod. Plant Resour., 3: 14-18.

  61. Parthasarathy, S., S. Ramanathan, V. Murugaiyah, M.R. Hamdan, M.I.M. Said, C.S. Lai and S.M. Mansor, 2013. A simple HPLC-DAD method for the detection and quantification of psychotropic mitragynine in Mitragyna speciosa (ketum) and its products for the application in forensic investigation. Forensic Sci. Int., 226: 183-187.
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  62. Nargis, J., K. Melati, C.S. Lai, O. Hasnah, K.C. Wong, M. Vikneswaran and K.Y. Khaw, 2013. Antioxidant, anti-cholinesterase and antibacterial activities of the bark extracts of Garcinia hombroniana. Afr. J. Pharm. Pharmacol., 7: 454-459.
    CrossRef  |  Direct Link  |  

  63. Mehdi, S.H., R.M. Ghalib, R. Hashim, F.M.C.G. da Silva and O. Sulaiman et al., 2013. Synthesis, characterization and cholinesterase enzymes inhibitory activity of 1-[3-methyl-5-(2,6,6-trimethyl- cyclohex-1-enyl)-4,5-dihydro-pyrazol-1-yl]-ethanone. J. Mol. Struct., 1049: 488-493.
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  64. Kunasundari, B., V. Murugaiyah, G. Kaur, H.J.M. Maurer and K. Sudesh, 2013. Revisiting the single cell protein application of Cupriavidus necator H16 and recovering bioplastic granules simultaneously. PLoS One, Vol. 8. 10.1371/journal.pone.0078528.
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  65. Kia, Y., H. Osman, R.S. Kumar, V. Murugaiyah, A. Basiri, S. Perumal and I.A. Razak, 2013. A facile chemo-, regio-and stereoselective synthesis and cholinesterase inhibitory activity of spirooxindole-pyrrolizine-piperidine hybrids. Bioorganic Med. Chem. Lett., 23: 2979-2983.
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  66. Kia, Y., H. Osman, R.S. Kumar, V. Murugaiyah and A. Basiri et al., 2013. Synthesis and discovery of novel piperidone-grafted mono-and bis-spirooxindole-hexahydropyrrolizines as potent cholinesterase inhibitors. Bioorganic Med. Chem., 21: 1696-1707.
    CrossRef  |  Direct Link  |  

  67. Fadaeinasab, M., A.H.A. Hadi, Y. Kia, A. Basiri and V. Murugaiyah, 2013. Cholinesterase enzymes inhibitors from the leaves of Rauvolfia reflexa and their molecular docking study. Molecules 18: 3779-3788.
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  68. Chan, Y.C., A.S.M. Ali, M. Khairuddean, K.Y. Khaw, V. Murugaiyah and A. Basiri, 2013. Synthesis and molecular modeling study of Cu(II) complexes derived from 2-(diphenylmethylene)hydrazinecarbothioamide derivatives with cholinesterase inhibitory activities. Chinese Chem. Lett., 24: 609-612.

  69. Basiri, A., V. Murugaiyah, H. Osman, R.S. Kumar, Y. Kia, K. Awang and M.A. Ali, 2013. An expedient, ionic liquid mediated multi-component synthesis of novel piperidone grafted cholinesterase enzymes inhibitors and their molecular modeling study. Eur. J. Med. Chem., 67: 221-229.
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  70. Basiri, A., V. Murugaiyah, H. Osman, R.S. Kumar, Y. Kia and M.A. Ali, 2013. Microwave assisted synthesis, cholinesterase enzymes inhibitory activities and molecular docking studies of new pyridopyrimidine derivatives. Bioorganic Med. Chem., 21: 3022-3031.
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  71. Aruldass, C.A., M.M. Marimuthu, S. Ramanathan, S.M. Mansor and V. Murugaiyah, 2013. Effects of Mesua ferrea leaf and fruit extracts on growth and morphology of Staphylococcus aureus. Microsc. Microanal., 19: 254-260.
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  72. Algariri, K., K.Y. Meng, I.J. Atangwho, M.Z. Asmawi, A. Sadikun, V. Murugaiyah and N. Ismai, 2013. Hypoglycemic and anti-hyperglycemic study of Gynura procumbens leaf extracts. Asian Pac. J. Trop. Biomed., 3: 358-366.
    CrossRef  |  Direct Link  |  

  73. Sundarasekar, J., J.J.J. Anthony, V. Murugaiyah and S. Subramaniam, 2012. Preliminary responses of 2,4-D and BAP on callus initiation of an important medicinal-ornamental Hymenocallis littoralis plants. J. Med. Plants Res., 6: 2088-2093.
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  74. Noormi, R., V. Sumathy, V. Murugaiyah and S. Subramaniam, 2012. Screening of potential antimicrobial activity from Hymenocallis littoralis (Jacq.) Salisb. Pharmacol. Online, 1: 93-98.

  75. Noormi, R., V. Murugaiyah and S. Subramaniam, 2012. Optimization of callus induction medium for Hymenocallis littoralis (Melong kecil) using root and bulb explants. J. Med. Plant Res., 6: 2309-2316.
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  76. Kia, Y., H. Osman, V. Murugaiyah, S. Arshad and I.A. Razak, 2012. (3E,5E)-3,5Bis(naphthalene-1-ylmethylidene)piperidin-4-one. Acta Crystallographica Sect. E, 68: o802-o803.

  77. Kia, Y., H. Osman, V. Murugaiyah, S. Arshad and I.A. Razak, 2012. (3E,5E)-3,5 Bis (4-methylbenzylidene)-1[3-(piperidin-1-yl)propanoyl]piperidin-4-one. Acta Crystallographica Sect. E, 68: o2493-o2494.

  78. Ghalib, R.M., R. Hashim, S.H. Mehdi, O. Sulaiman and P.S.P. Silva et al., 2012. Synthesis of ninhydrin derivatives and their anticancer, antimicrobial and cholinesterase enzymes inhibitory activities. Lett. Drug Des. Discov., 9: 767-774.
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  79. Ghalib, R.M., R. Hashim, S.F. Alshahateet, S.H. Mehdi and O. Sulaiman et al., 2012. Synthesis, antimicrobial and cholinesterase enzymes inhibitory activities of indeno imidazoles and x-ray crystal structure of 3a,8a-dihydroxy-1,3-diphenyl-1,3,3a,8a-tetrahydro-indeno [1,2-d] imidazole-2,8-dione. J. Chem. Crystallography, 42: 783-789.
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  80. Beh, H.K., L.J. Seow, M.A. Asmawi, A.M.S.A. Majid, V. Murugaiyah, N. Ismail and Z. Ismail, 2012. Anti-angiogenic activity of Morinda citrifolia extracts and its chemical constituents. Nat. Prod. Res., 26: 1492-1497.
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  81. Teh, C.H., V. Murugaiyah and K.L. Chan, 2011. Developing a validated liquid chromatography-mass spectrometric method for the simultaneous analysis of five bioactive quassinoid markers for the standardization of manufactured batches of Eurycoma longifolia Jack extract as antimalarial medicaments. J. Chromatogr. A, 1218: 1861-1877.
    CrossRef  |  

  82. Seow, L.J., H.K. Beh, A.M.S.A. Majid, V. Murugaiyah, N. Ismail and M.Z. Asmawi, 2011. Anti-angiogenic activity of Gynura segetum leaf extracts and its fractions. J. Ethnopharmacol., 134: 221-227.
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  83. Mehdi, S.H., R. Hashim, R.M. Ghalib, M.F.C.G. da Silva and O. Sulaiman et al., 2011. Synthesis, characterization, antimicrobial and enzymatic activity of 4b,9b-dihydroxy-7,8-dihydro-4bH-indeno [1,2-b] benzofuran-9,10(6H,9bH)-dione. J. Mol. Struct., 1006: 318-323.
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  84. Kia, Y., H. Osman, V. Murugaiyah, M. Hemamalini and H.K. Fun, 2011. (E)-2-(4- Methylbenzylidene)hydrazinecarboxamide. Acta Crystallographica Sect. E, 67: o242-o242.
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  85. Kia, Y., H. Osman, V. Murugaiyah, M. Hemamalini and H.K. Fun, 2011. (3E,5E)-3,5-Dibenzylidene-1-[3-(piperidin-1-yl)propanoyl]piperidin-4-one. Acta Crystallographica Sect. E, 67: o1299-o1300.

  86. Ghalib, R.M., R. Hashim, S.F. Alshahateet, S.H. Mehdi, O. Sulaiman, V. Murugaiyah and C.A. Aruldass, 2011. Synthesis, supramolecularity and in vitro antimicrobial activity of 3a,8a-dihydroxy-2-thioxo-1,3,3a,8a-tetrahydroindeno [1,2-d] imidazol-8(2H)-one. J. Mol. Struct., 1005: 152-155.
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  87. Basiri, A., V. Murugaiyah, H. Osman, M. Hemamalini and H.K. Fun, 2011. (3E,5E)-1-Acryloyl-3,5-bis(2,4-dichlorobenzylidene)piperidin-4-one hemihydrate. Acta Crystallographica Sect. E, 67: o1301-o1302.

  88. Basiri, A., V. Murugaiyah, H. Osman, M. Hemamalini and H.K. Fun, 2011. (3E,5E)-1-Acryloyl-3,5-bis(2-chlorobenzylidene)piperidin-4-one. Acta Crystallographica Sect. E, 67: o1228-o1229.

  89. Seow, L.J., H.K. Beh, A.M.S. Majid, V. Murugaiyah, N. Ismail and M.Z. Asmawi, 2010. Antiangiogenic activity of Gynura segetum leaf extracts and its fractions. Malaysian J. Pharm. Sci., 1: 32-32.

  90. Sandrasagaran, U.M., S. Ramanathan, S. Subramnaniam, S.M. Mansor and V. Murugaiyah, 2010. Antimicrobial activity of Dendrobium crumenatum (Pigeon Orchid). Malaysian J. Pharm. Sci., 1: 111-112.

  91. Parthasarathy, S., S. Ramanathan, S. Ismail, M.I. Adenan, S.M. Mansor and V. Murugaiyah, 2010. Determination of mitragynine in plasma with solid-phase extraction and rapid HPLC-UV analysis and its application to a pharmacokinetic study in rat. Anal. Bioanal. Chem., 397: 2023-2030.
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  92. Noormi, R., S. Subramaniam, V. Murugaiyah and J. Sundarasekar, 2010. Qualitative determinations of potential lycorine alkaloid in Hymenocallis littoralis (Melong Kecil). Malaysian J. Pharm. Sci., 1: 74-74.

  93. Marimuthu, M.M., S.M. Mansor, V. Murugaiyah and S. Ramanathan, 2010. Antimicrobial activity of methanolic extracts of various parts of Ixora coccinea. Malaysian J. Pharm. Sci., 1: 46-46.

  94. Liew, W.L., V. Murugaiyah and K.L. Chan, 2010. Inhibitory activities of Andrographis paniculata and its fractions on acetylcholinesterase and butyrlcholinesterase enzymes: A source for potential anti-alzheimer’s drugs. Malaysian J. Pharm. Sci., 1: 56-57.

  95. Lee, Y.E., V. Murugaiyah and K.L. Chan, 2010. Acetylcholinesterase and butyrlcholinesterase inhibitory activities of Ailanthus malabarica and its fractions: A source for potential anti-alzheimer’s drugs. Malaysian J. Pharm. Sci., 1: 55-56.

  96. Kuong, Y.M., A. Sadikun, V. Murugaiyah and M.Z. Asmawi, 2010. Determination of flavonoids and chlorogenic acid in Gynura procumbens by a simple high performance liquid chromatography method with ultraviolet detection (HPLC-UV). Malaysian J. Pharm. Sci., 1: 9-10.

  97. Krishnan, N., S. Ramanathan, S. Sasidharan, V. Murugaiyah and S.M. Mansor, 2010. Antimicrobial activity evaluation of Cassia spectabilis leaf extracts. Int. J. Pharmacol., 6: 510-514.
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  98. Koay, Y.H., V. Murugaiyah and K.L. Chan, 2010. Evaluation of cholinesterase inhibitory activity of Phyllanthus niruri. Malaysian J. Pharm. Sci., 1: 44-44.

  99. Beh, H.K., L.J. Seow, M.Z. Asmawi, A.M.S. Majid, V. Murugaiyah, Z. Ismail and N. Ismail, 2010. Antiangiogenic activity of Morinda citrifolia extracts and its chemical constituents. Malaysian J. Pharm. Sci., 1: 10-11.

  100. Aruldass, C.A., S. Ramanathan, S.M. Mansor and V. Murugaiyah, 2010. Antimicrobial activity of methanolic extrcats of various parts of Mesua ferrea. Malaysian J. Pharm. Sci., 1: 45-45.

  101. Murugaiyah, V. and K.L. Chan, 2009. Mechanisms of antihyperuricemic effect of Phyllanthus niruri and its lignan constituents. J. Ethnopharmacol., 124: 233-239.
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  102. Murugaiyah, V. and K.L. Chan, 2007. Determination of four lignans in Phyllanthus niruri L. by a simple high-performance liquid chromatography method with fluorescence detection. J. Chromatogr. A, 1154: 198-204.
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  103. Murugaiyah, V. and K.L. Chan, 2007. Analysis of lignans from Phyllanthus niruri L. in plasma using a simple HPLC method with fluorescence detection and its application in a pharmacokinetic study. J. Chromatogr. B, 852: 138-144.
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  104. Murugaiyah, V. and K.L. Chan, 2006. Antihyperuricemic lignans from the leaves of Phyllanthus niruri. Planta Med., 72: 1262-1267.
    CrossRef  |  PubMed  |  Direct Link  |  

  105. Murugaiyah, V. and K.L. Chan, 2005. Xanthine oxidase inhibitory activity of some Malaysian plants. Malaysian J. Sci., 24: 263-266.
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