Dr. Thanusak Tatu

Associated Medical Science
Chiang Mai University, Thailand

Highest Degree
Ph.D. in Clinical Biochemistry and Molecular Genetics from University of Oxford, United Kingdom

My URL
https://livedna.org/66.18230

Share this Profile

Area of Interest:

Molecular Sciences
Molecular Genetics
Pathophysiology
Biochemistry
Thalassemia

Selected Publications

  1. Leckngam, P., E. Limweeraprajak, T. Kiewkarnkha and T. Tatu, 2017. The Hb E (HBB: c. 79G>A), mean corpuscular volume, mean corpuscular hemoglobin cutoff points in double heterozygous Hb E/-SEA α-thalassemia-1 carriers are dependent on hemoglobin levels. Hemoglobin, 41: 38-43.
    CrossRef  |  Direct Link  |  

  2. Pakdeepak, K., S. Pata, S. Chiampanitchayakul, W. Kasinrerk and T. Tatu, 2016. Production of monoclonal antibodies against intact a-globin chain-containing hemoglobins for detecting a-thalassemia disease. J. Immunoassay Immunochem., 37: 564-571.

  3. Deengam, T., T. Tatu, W. Suttana and C. Singharachai, 2016. Prevalence of carriers of thalassemia and hemoglobinopathies in ethnic groups’ pregnant women and spouses at the antenatal clinic mae fah luang hospital, Chiang Rai (2552-2556 BE). J. Health Res., 30: 59-65.
    Direct Link  |  

  4. Tangpan, L. and T. Tatu, 2015. Closed relationship of βE-allele and high HbF associated cis-loci: Case studies in Thai HbE/β-thalassemia families. Bull. Chiang Mai Assoc. Med. Sci., 48: 88-99.
    Direct Link  |  

  5. Pakdeepak, K., S. Kerdpoo and T. Tatu, 2015. Fast preparative separation of Hbs A, A2, E, F, Bart's and Portland I. Bull. Chiang Mai Assoc. Med. Sci., 48: 100-106.

  6. Tatu, T., W. Sritong and T. Sa-nguansermsri, 2014. The associations of SEA-a thalassemia 1, XmnI-G-polymorphism and a-globin gene mutations with the clinical severity of a-thalassemia syndrome in Northern Thailand. J. Med. Assoc. Thai, 97: 300-307.

  7. Pata, S., S. Khummuang, S. Pornprasert, T. Tatu and W. Kasinrerk, 2014. A simple and highly sensitive ELISA for screening of the α-thalassemia-1 Southeast Asian-type deletion. J. Immunoassay Immunochem., 35: 194-206.
    CrossRef  |  Direct Link  |  

  8. Kerdpoo, S., E. Limweeraprajak and T. Tatu, 2014. Effect of Swiss-type heterocellular HPFH from XmnI-Gγ and HBBP1 polymorphisms on HbF, HbE, MCV and MCH levels in Thai HbE carriers. Int. J. Hematol., 99: 338-344.
    CrossRef  |  Direct Link  |  

  9. Srisuwan, W. and T. Tatu, 2013. Diagnosis of thalassemia carriers common in the northern Thailand via a combination of MCV or MCH and PCR-based methods. Bull. Chiang Mai Assoc. Med. Sci., 46: 22-32.

  10. Tatu, T., T. Kiewkarnkha, S. Khuntarak, S. Khamrin, S. Suwannasin and W. Kasinrerk, 2012. Screening for co-existence of α-thalassemia in β-thalassemia and in HbE heterozygotes via an enzyme-linked immunosorbent assay for Hb Bart's and embryonic zeta-globin chain. Int. J. Hematol., 95: 386-393.
    CrossRef  |  Direct Link  |  

  11. Tatu, T. and W. Kasinrerk, 2012. A novel test tube method of screening for hemoglobin E. Int. J. Laboratory Hematol., 34: 59-64.
    CrossRef  |  Direct Link  |  

  12. Tatu, T., P. Sakdasirisathaporn, W. Wongchompoo and W. Nawarawong, 2011. HbE and HbE in HbE/β°-thalassemia are heterogeneous. Bull. Chiang Mai Assoc. Med. Sci., 44: 17-23.

  13. Kuntaruk, S., T. Tatu, T. Keowkarnkah and W. Kasinrerk, 2010. Sanwich ELISA for HbA2 quantification and identification of β-thalassemia carriers. Int. J. Hematol., 91: 219-228.

  14. Tayapiwatana, C., S. Kuntaruk, T. Tatu, S. Chiampanichayakul and T. Munkongdee et al., 2009. Simple method for screening of α-thalassaemia 1 carriers. Int. J. Hematol., 89: 559-567.
    CrossRef  |  Direct Link  |  

  15. Kewkarnkha, T., S. Suwannasin and T. Tatu, 2009. Evaluation of efficiencies of MCV, HbH inclusion body test and Gap-PCR in the screening of α-thalassemia: A case study of Lampang hospital. Bull. Chiang Mai Assoc. Med. Sci., 42: 95-101.
    Direct Link  |  

  16. Briand, N., S. Pornprasert, N. Ngo-Giang-Huong, F. Galacteros and S. Pissard et al., 2009. Perinatal zidovudine prophylaxis in HIV type-1-infected pregnant women with thalassemia carriage in Thailand. Antiviral Therapy, 14: 117-122.

  17. Tatu, T., D. Prakunwisit, S. Chayajak, S. Chiampanichayakul and W. Kasinrerk, 2007. RBC count and its differentiation potential between -thalassemia (SEA type), β-thalassemia and HbE heterozygotes. CMUJ Nat. Sci., 6: 57-64.

  18. Tatu, T., W. Nawarawong and T. Sa-nguansermsri, 2006. Zinc Protoporphyrin (ZPP) Status in Thai β-Thalassemia and Hb H disease. CMU J., 5: 209-218.
    Direct Link  |  

  19. Tatu, T., T. Suyaraj, R. Saetang and T. Sa-nguansermsri, 2006. Hb E/β-thalassemia with unusual Hb pattern: A pitfall in laboratory thalassemia diagnosis. J. Med. Tech. Assoc. Thailand, 34: 1646-1654.

  20. Tatu, T. and P. Lertkham, 2006. Type and quantity of hemoglobins in HbH disease after separation by weak-cation exchange High Performance Liquid Chromatography (HPLC). Bull. Chiang Mai Assoc. Med. Sci., 39: 3-7.
    Direct Link  |  

  21. Sritong, W., T. Tatu, R. Saetung and T. Sa-nguansermsri, 2004. Rapid identification of b-thalassemia mutations by mutagenically separated polymerase chain reaction (MS-PCR). Chiang Mai Med. Bull., 43: 133-141.

  22. Tatu, T., S. Jannoi, K. Jamwuttipreecha and T. Sa-nguansermsri, 2003. Screening for β-thalassemia 1 using the Dried Brilliant Cresyl Blue method. Thai J. Hematol. Transf. Med., 13: 315-320.

  23. Tatu, T., 2003. Effect of snake venom on hemostasis. Bull. Chiangmai Assoc. Med. Sci., 36: 222-226.

  24. Tatu, T. and P. Vatcharasuwan, 2003. Comparison of efficacies of red cell indicies and one tube osmotic fragility test in thalassemia screen. J. Med. Tech. Assoc. Thailand, 31: 321-334.

  25. Tatu, T. and P. Kulpongs, 2003. Hb F and F cell production in human adults (Review). Thai J. Hematol. Transf. Med., 13: 341-346.

  26. Tatu, T., S. Phohirun and S.L. Thein, 2002. Incidence of heterocellular HPFH among Thais: A preliminary report. Bull. Chiang Mai Assoc. Med. Sci., 35: 164-169.

  27. Garner, C.P., T. Tatu, S. Best, L. Creary and S.L. Thein, 2002. Evidence of genetic interaction between the β-globin complex and chromosome 8q in the expression of fetal hemoglobin. Am. J. Hum. Genet., 70: 793-799.
    CrossRef  |  Direct Link  |  

  28. Tatu, T. and S.L. Thein, 2001. Automated genotyping for accurate assignment of the (AT) xNz (AT) y motif within the β‐globin locus control region‐hypersensitive site 2. Br. J. Haematol., 112: 488-492.
    CrossRef  |  Direct Link  |  

  29. Garner, C., T. Tatu, L. Game, L.R. Cardon, T.D. Spector, M. Farrall and S.L. Thein, 2000. A candidate gene study of F cell levels in sibling pairs using a joint linkage and association analysis. GeneScreen, 1: 9-14.
    CrossRef  |  Direct Link  |  

  30. Garner, C., T. Tatu, J.E. Reittie, T. Littlewood and J. Darley et al., 2000. Genetic influences on F cells and other hematologic variables: A twin heritability study. Blood, 95: 342-346.
    Direct Link  |  

  31. Tatu, T., T. Tositarak, S. Jannoi, D. Pintanonda and P. Chanarat, 1998. Difference of parameters among different osmotically fragile red blood cells. J. Med. Tech. Assoc. Thailand, 26: 93-96.

  32. Tatu, T., P. Gategasem and P. Hathirat, 1997. Hemoglobin typing by high performance liquid chromatography. Southeast Asian J. Trop. Med. Public Health, 28: 417-423.
    Direct Link  |  

  33. Tatu, T., L.O. Suwanchompoo, S. Jannoi and T. Sanguansermsri, 1997. The ability of hematologic parameters in prediction of heterozygote of severe type of α-thalassemia (α-Thalassemia 1): Preliminary study. Bull. Chiang Mai Assoc. Med. Sci., 30: S62-S69.
    Direct Link  |  

  34. Tatu, T., 1997. The separation and quantitation of hemoglobins by HPLC. J. Assoc. Med. Sci., 30: 64-68.
    Direct Link  |  

  35. Kajanachumpol, S., T. Tatu, W. Sasanakul, A. Chuansumrit and P. Hathirat, 1997. Zinc and copper status of thalassemic children. Southeast Asian J. Trop. Med. Public Health, 28: 877-880.
    Direct Link  |  

  36. Hathirat, P., T. Tatu, S. Ajjimakorn, P. Kaidkaseam and W. Sasanakul, 1997. Prenatal diagnosis of β-thalassemia by Chorionic Villi Sampling (CVS) in Ramathibodi hospital. Thai J. Hematol. Transf. Med., 7: 3-5.

  37. Tatu, T., U. Udomsappayakul, K. Pumala, O. Puchaiwattananon and P. Hathirat, 1996. The study of zinc protoporphyrin (ZPP) in normal Thai men. Thai J. Hematol. Transf. Med., 6: 112-117.

  38. Tatu, T., S. Ajjimakorn, P. Hathirat, A. Chuansumrit and P. Isarangura, 1996. Prenatal diagnosis of fetus at risk for thalassemia and hemoglobinopathies in Ramathibodi hospital: From the past till now. Thai J. Hematol. Transf. Med., 6: 134-140.

  39. Tatu, T., P. Kaidkaseam, P. Hathirat, S. Ajjimakorn, R. Wisedpanichkij and A. Bunyaratvej, 1995. Prenatal diagnosis of β-thalassemia/HbE disease by high performance liquid chromatography. Rama Med. J., 18: 159-163.

  40. Rueangwetsawat, Y., T. Tatu, P. Hathirat, W. Sasanakul and A. Chuansumrit, 1995. Urinary iron excretion of different doses of desferoxamine in thalassemia. Thai J. Hematol. Transf. Med., 5: 32-35.

  41. Siritorn, S., P. Hathirat, W. Mahaphan, T. Tatu, J. Kittikul and P. Isarangura, 1994. Iron status of β-thalassemia major. Thai J. Hematol. Transf. Med., 4: 135-138.

  42. Sasanakul, W., T. Tatu, S. Ajjimakorn, W. Mahaphan, P. Hathirat, A. Chuansumrit and P. Isarangura, 1994. Prenatal diagnosis of thalassemia: Ramathibodi experience. Thai J. Hematol. Transf. Med., 4: 5-10.

  43. Hathirat, P., T. Tatu, A. Armiroh, W. Sasanakul and J. Kittikul, 1994. Iron status of β-thalassemia/HbE children. Thai J. Hematol. Transf. Med., 4: 131-134.

  44. Tanapothiwirat, W., S. Ajjimakorn, W. Sasanakul, T. Tatu, P. Hathirat, A. Chuansumrit and P. Isarangura, 1990. Prenatal diagnosis of thalassemia: Report of the first 2 cases at ramathibodi hospital. Rama Med. J., 13: 196-200.
Member since October, 2017