Dr. Minoru Sasaki

Professor
Iwate Medical University, Japan

Highest Degree
Doctorate in Microbiology from Tohoku Medical and Pharmaceutical University, Japan

My URL
https://livedna.org/81.23694

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Area of Interest:

Biomedical Sciences
Microbiology
Pharmacology
Biomedicine
Dentistry

Selected Publications

  1. Sekiya, M., Y. Shimoyama, T. Ishikawa, M. Sasaki, M. Futai and M. Nakanishi-Matsui, 2018. Porphyromonas gingivalis is highly sensitive to inhibitors of a proton-pumping ATPase. Biochem. Biophys. Res. Commun., 498: 837-841.
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  2. Sasaki, M., Y. Kodama, Y. Shimoyama, T. Ishikawa and S. Kimura, 2018. Aciduricity and acid tolerance mechanisms of Streptococcus anginosus. J. Gen. Applied Microbiol. (In Press). .

  3. Hatakeyama, W., M. Taira, H. Kihara, M. Sasaki, S. Kimura and H. Kondo, 2012. Subcutaneous tissue reactions against nano-apatite collagen composites. Nano Biomed., 4: 118-124.
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  4. Taira, M., Y. Shimoyama, T. Kagiya, M. Sasaki, T. Nezu, H. Harada and S. Kimura, 2011. Proteome analyses of human macrophages exposed to low cytotoxic IC90 copper (2+) ions. Dental Mater. J., 30: 293-299.
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  5. Taira, M., T. Kagiya, M. Sasaki and S. Kimura, 2011. Quantitative real-time RT-PCR analyses of DNA-damage-recovery-related gene expressions of mouse macrophage-like cell line RAW264 when exposed to IC50 nickel ions. Nano Biomed., 3: 294-299.
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  6. Taira, M., T. Kagiya, H. Harada, M. Sasaki, S. Kimura, T. Narushima and Y. Araki, 2010. Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles. J. Mater. Sci.-Mater. Med., 21: 267-275.
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  7. Saitoh, S., K. Sasaki, T. Nezu, M. Taira, Y. Shimoyama, M. Sasaki and K. Ishizeki, 2010. Histological and TEM observation of subcutaneous tissues exposed to particulate copper, nickel and titanium. J. Oral Tissue Eng., 8: 102-106.
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  8. Taira, M., T. Nezu, M. Sasaki, S. Kimura, T. Kagiya, H. Harada and Y. Araki, 2009. Gene expression analyses of human macrophage phagocytizing sub-μ titanium particles by allergy DNA chip (Genopal TM). Bio-Med. Mater. Eng., 19: 63-70.
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  9. Taira, M., T. Kagiya, M. Sasaki, K. Sasaki, S. Saitoh, T. Nezu and Y. Araki, 2009. First-stage genome-wide gene expression analyses of human mesenchymal stem cells exposed to IC50 Ni2+ ions. J. Oral Tissue Eng., 7: 107-120.
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  10. Taira, M., M. Sasaki, S. Kimura and Y. Araki, 2009. Characterization of aerosols and fine particles produced in dentistry and their health risk assessments. Nano Biomed., 1: 9-15.
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  11. Taira, M., M. Sasaki, K. Sasaki, S. Saitoh, T. Nezu, S. Kimura and Y. Araki, 2009. DNA microarray analyses of the effects of LPS-stimulation and IC50 nickel ions on gene expressions of mouse macrophage-like cell line RAW264. Nano Biomed., 1: 59-69.
    CrossRef  |  Direct Link  |  

  12. Taira, M., M. Sasaki, S. Kimura and Y. Araki, 2008. Dose-dependent effects of Ni (II) ions on production of three inflammatory cytokines (TNF-α, IL-1β and IL-6), superoxide dismutase (SOD) and free radical NO by murine macrophage-like RAW264 cells with or without LPS-stimulation. J. Mater. Sci.: Mater. Med., 19: 2173-2178.
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  13. Taira, M., K. Sasaki, S. Saitoh, T. Nezu, T. Kagiya, H. Harada and Y. Araki, 2008. TEM/EDX observation of micro-beads of Magnetically Activated Cell Sorting (MACS) system and separation trial of mouse mesenchymal stem cells from bone marrow cells by MACS system. J. Oral Tissue Eng., 6: 33-40.
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  14. Taira, M., K. Sasaki, S. Saitoh, T. Nezu, M. Sasaki, S. Kimura and Y. Araki, 2006. Accumulation of element Ti in macrophage-like RAW264 cells cultured in medium with 1 ppm Ti and effects on cell viability, SOD production and TNF-α secretion. Dental Mater. J., 25: 726-732.
    CrossRef  |  Direct Link  |  

  15. Taira, M., M. Sasaki, S. Kimura and Y. Araki, 2005. Microarray analysis of the cell cycle-related gene expression from a RAW264 murine macrophage cell line in response to lipopolysaccharide. Int. Congress Series., 1284: 205-206.
    CrossRef  |  Direct Link  |  

  16. Taira, M., M. Sasaki, C. Yamaura-Tanaka, S. Saitoh, S. Kimura and Y. Araki, 2005. Effects of Ni2+ ions on cell viability and NO production of murine peritoneal exudate cells (Macrophages) with and without lipopolysaccharide stimulation. Dental Mater. J., 24: 304-310.
    CrossRef  |  Direct Link  |  

  17. Sasaki, M., C. Yamaura, Y. Ohara‐Nemoto, S. Tajika, Y. Kodama, T. Ohya and S. Kimura, 2005. Streptococcus anginosus infection in oral cancer and its infection route. Oral Dis., 11: 151-156.
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  18. Ohara-Nemoto, Y., K. Kishi, M. Satho, S. Tajika, M. Sasaki, A. Namioka and S. Kimura, 2005. Infective endocarditis caused by Granulicatella elegans originating in the oral cavity. J. Clin. Microbiol., 43: 1405-1407.
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  19. Ohara-Nemoto, Y., Y. Ikeda, M. Kobayashi, M. Sasaki, S. Tajika and S. Kimura, 2002. Characterization and molecular cloning of a glutamyl endopeptidase from Staphylococcus epidermidis. Microb. Pathogen., 33: 33-41.
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  20. Sasaki, M., Y. Ohara-Nemoto, S. Tajika, M. Kobayashi, C. Yamaura and S. Kimura, 2001. Antigenic characterisation of a novel Streptococcus anginosus antigen that induces nitric oxide synthesis by murine peritoneal exudate cells. J. Med. Microbiol., 50: 952-958.
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  21. Sasaki, M., Y. Ohara-Nemoto, S. Tajika, M. Kobayashi, Y. Ikeda, M. Kaneko and T. Takagi, 1998. Purification and characterization of a glutamic acid-specific protease from Staphylococcus epidermidis. Jpn. J. Oral Biol., 40: 542-548.
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  22. Ohara-Nemoto, Y., S. Tajika, M. Sasaki and M. Kaneko, 1997. Identification of abiotrophia adiacens and abiotrophia defectiva by 16S rRNA gene PCR and restriction fragment length polymorphism analysis. J. Clin. Microbiol., 35: 2458-2463.
    Direct Link  |  

  23. Sasaki, M., Y. Ohara-Nemoto, S. Tajika and M. Kaneko, 1995. Induction of inflammatory cytokine and cyclooxygenase-2 mRNA expression by secreted substances from oral streptococci. Dent. J. Iwate Med. Univ., 20: 284-290.
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  24. Ohara-Nemoto, Y., M. Sasaki, M. Kaneko, T. Nemoto and M. Ota, 1994. Cysteine protease activity of streptococcal pyrogenic exotoxin B. Can. J. Microbiol., 40: 930-936.
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  25. Ishikawa, M., M. Sasaki, K. Koiwai, M. Ozaki, Y. Takayanagi and K. Sasaki, 1992. Inhibition of hepatic mixed-function oxidase enzymes in mice by acute and chronic treatment with selenium. J. Pharmacobio-Dyn., 15: 377-385.
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  26. Ishikawa, M., K. Tanno, M. Sasaki, Y. Takayanagi and K.I. Sasaki, 1990. Antidotal effect of lipopolysaccharide against acetaminophen-induced mortality in mice. Basic Clin. Pharmacol. Toxicol., 67: 387-391.
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  27. Ishikawa, M., M. Sasaki, K. Sasaki and Y. Takayanagi, 1989. Micro scale. Rapid and simple determination of tegafur (FT) by high pressure liquid chromatography in plasma. Res. Commun. Chem. Pathol. Pharmacol., 64: 347-350.
    PubMed  |  Direct Link  |  

  28. Sasaki, K.I., M. Sasaki, M. Ishikawa and G. Takayanagi, 1986. Different depressing effects of lentinan on the increases of cytochrome P-450-dependent monooxygenase activities induced in mice by phenobarbital and by 3-methylcholanthrene. Chem. Pharm. Bull., 34: 1309-1314.
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  29. Sasaki, K.I., M. Sasaki, M. Ishikawa and G. Takayanagi, 1985. Depression of hepatic microsomal enzyme systems by lentinan in mice. Jpn. J. Pharmacol., 37: 107-115.
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Member since April, 2018