Prof. Jong-Sup Bae

Professor & Vice Dean
Kyungpook National University, South Korea

Highest Degree
Ph.D. in Biochemistry from Saint Louis University, USA

My URL
https://livedna.org/82.16434

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Area of Interest:

Biomedical Sciences
Cell Physiology
Inflammation
Biochemistry
Haemostasis

Selected Publications

  1. Yun, J.H., S.W. Park, K.J. Kim, J.S. Bae and E.H. Lee et al., 2017. Endothelial STAT3 activation increases vascular leakage through downregulating tight junction proteins: Implications for diabetic retinopathy. J. Cell. Physiol., 232: 1123-1134.
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  2. Min, G., S.K. Ku, T. Lee and J.S. Bae, 2017. Suppressive effects of zingerone on TGFBIp-mediated septic responses. Arch. Pharmacal Res., (In Press). 10.1007/s12272-017-0919-9.
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  3. Lee, W., S.K. Ku, M.A. Kim and J.S. Bae, 2017. Anti-factor Xa activities of zingerone with anti-platelet aggregation activity. Food Chem. Toxicol., 105: 186-193.
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  4. Lee, S.H., W. Lee, T. Nguyen, I.S. Um, J.S. Bae and E. Ma, 2017. Synthesis and thrombin, factor Xa and U46619 inhibitory effects of non-amidino and amidino N2-thiophenecarbonyl- and N2-tosylanthranilamides. Int. J. Mol. Sci., Vol. 18, No. 6. 10.3390/ijms18061144.
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  5. Lee, J., W. Lee, M. Kim, J.S. Hwang, M. Na and J.S. Bae, 2017. Inhibition of platelet aggregation and thrombosis by indole alkaloids isolated from the edible insect Protaetia brevitarsis seulensis (Kolbe). J. Cell. Mol. Med., 21: 1217-1227.
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  6. Lee, I.C., J. Kim and J.S. Bae, 2017. Anti-inflammatory effects of dabrafenib in vitro and in vivo. Can. J. Physiol. Pharmacol., 95: 697-707.
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  7. Lee, I.C. and J.S. Bae, 2017. Suppressive effects of pelargonidin on PolyPhosphate-mediated vascular inflammatory responses. Arch. Pharmacal Res., 40: 258-267.
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  8. Kwak, S., S.K. Ku, H. Kang, M.C. Baek and J.S. Bae, 2017. Methylthiouracil, a new treatment option for sepsis. Vasc. Pharmacol., 88: 1-10.
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  9. Ku, S.K., J. Kim, S.C. Kim and J.S. Bae, 2017. Suppressive effects of dabrafenib on endothelial protein C receptor shedding. Arch. Pharmacal Res., 40: 282-290.
    CrossRef  |  Direct Link  |  

  10. Kang, H., S.K. Ku, J. Kim, J. Chung and S.C. Kim et al., 2017. Anti-vascular inflammatory effects of pentacyclic triterpenoids from Astilbe rivularis in vitro and in vivo. Chem.-Biol. Interact., 261: 127-138.
    CrossRef  |  Direct Link  |  

  11. Jeong, S., S.K. Ku and J.S. Bae, 2017. Anti-inflammatory effects of pelargonidin on TGFBIp-induced responses. Can. J. Physiol. Pharmacol., 95: 372-381.
    CrossRef  |  Direct Link  |  

  12. Yang, E.J., W. Lee, K.S. Song and J.S. Bae, 2016. Ameliorative effect of a rarely occurring C-methylrotenoid on HMGB1-induced septic responses in vitro and in vivo. Biochem. Pharmacol., 110: 58-70.
    CrossRef  |  Direct Link  |  

  13. Min, G., S.K. Ku, S. Jeong, M.C. Baek and J.S. Bae, 2016. Suppressive effects of methylthiouracil on polyphosphate-mediated vascular inflammatory responses. J. Cell. Mol. Med., 20: 2333-2340.
    CrossRef  |  Direct Link  |  

  14. Min, G., S.K. Ku, M.S. Park, T.J. Park, H.S. Lee and J.S. Bae, 2016. Anti-septic effects of pelargonidin on HMGB1-induced responses in vitro and in vivo. Arch. Pharmacal Res., 39: 1726-1738.
    CrossRef  |  Direct Link  |  

  15. Lee, W., S.K. Ku, S. Park, K.M. Kim, H. Choi and J.S. Bae, 2016. Inhibitory effect of three diketopiperazines from marine-derived bacteria on HMGB1-induced septic responses in vitro and in vivo. Am. J. Chin. Med., 44: 1145-1166.
    CrossRef  |  Direct Link  |  

  16. Lee, W., S.K. Ku, H. Choi and J.S. Bae, 2016. Inhibitory effects of three diketopiperazines from marine-derived bacteria on endothelial protein C receptor shedding in human endothelial cells and mice. Fitoterapia, 110: 181-188.
    CrossRef  |  Direct Link  |  

  17. Lee, W., J. Lee, R. Kulkarni, M.A. Kim, J.S. Hwang, M. Na and J.S. Bae, 2016. Antithrombotic and antiplatelet activities of small-molecule alkaloids from Scolopendra subspinipes mutilans. Scient. Rep., Vol. 6. 10.1038/srep21956.
    CrossRef  |  Direct Link  |  

  18. Lee, W., E.J. Yang, D.H. Park and J.S. Bae, 2016. Suppressive effects of polyozellin on endothelial protein C receptor shedding via inhibiting TACE activity and MAP kinases. Fitoterapia, 108: 26-32.
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  19. Lee, W., E.J. Park, S. Kwak, K.C. Lee, D.H. Na and J.S. Bae, 2016. Trimeric PEG-conjugated Exendin-4 for the treatment of sepsis. Biomacromolecules, 17: 1160-1169.
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  20. Lee, S.H., W. Lee, J.S. Bae and E. Ma, 2016. Synthesis and in vitro and in vivo anticoagulant and antiplatelet activities of amidino- and non-amidinobenzamides. Molecules, Vol. 21, No. 5. 10.3390/molecules21050676.
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  21. Lee, S., S.K. Ku and J.S. Bae, 2016. Anti-inflammatory effects of dabrafenib on polyphosphate-mediated vascular disruption. Chemico-Biol. Interact., 256: 266-273.
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  22. Lee, I.C. and J.S. Bae, 2016. Anti-inflammatory effects of vicenin-2 and scolymoside on polyphosphate-mediated vascular inflammatory responses. Inflamm. Res., 65: 203-212.
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  23. Lee, D., S. Lee, K.H. Liu, J.S. Bae, D.J. Baek and T. Lee, 2016. Solid-phase synthesis of 1,3,7,8-tetrasubstituted xanthine derivatives on traceless solid support. ACS Combinatorial Sci., 18: 70-74.
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  24. Ku, S.K., E.K. Yoon, W. Lee, S. Kwon, T. Lee and J.S. Bae, 2016. Antithrombotic and antiplatelet activities of pelargonidin in vivo and in vitro. Arch. Pharmacal Res., 39: 398-408.
    Direct Link  |  

  25. Ku, S.K., E.J. Yang, H. Kang, B. Jung and J.S. Bae, 2016. Inhibitory effect of polyozellin on secretory group IIA phospholipase A2. Arch. Pharmacal Res., 39: 271-278.
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  26. Ku, S.K. and J.S. Bae, 2016. Vicenin-2 and scolymoside inhibit high-glucose-induced vascular inflammation in vitro and in vivo. Can. J. Physiol. Pharmacol., 94: 287-295.
    CrossRef  |  Direct Link  |  

  27. Kim, J., J. Kim and J.S. Bae, 2016. ROS homeostasis and metabolism: A critical liaison for cancer therapy. Exp. Mol. Med., Vol. 48. 10.1038/emm.2016.119.
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  28. Kim, J. and J.S. Bae, 2016. Tumor-associated macrophages and neutrophils in tumor microenvironment. Mediators Inflammation, Vol. 2016. 10.1155/2016/6058147.
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  29. Kang, H., T. Lee and J.S. Bae, 2016. Suppressive effects of pelargonidin on endothelial protein C receptor shedding via the inhibition of TACE activity and MAP kinases. Am. J. Chin. Med., 44: 771-784.
    CrossRef  |  Direct Link  |  

  30. Kang, H., S.K. Ku, H. Choi and J.S. Bae, 2016. Three diketopiperazines from marine-derived bacteria inhibit LPS-induced endothelial inflammatory responses. Bioorg. Med. Chem. Lett., 26: 1873-1876.
    CrossRef  |  Direct Link  |  

  31. Jung, B., S.K. Ku, M. Gao, K.M. Kim, M.S. Han, H. Choi and J.S. Bae, 2016. Suppressive effects of three diketopiperazines from marine-derived bacteria on TGFBIp-mediated septic responses in human endothelial cells and mice. Arch. Pharmacal Res., 39: 843-854.
    CrossRef  |  Direct Link  |  

  32. Jung, B., J. Kim and J.S. Bae, 2016. Dabrafenib, as a novel insight into drug repositioning against Secretory Group IIA phospholipase A2. Int. J. Pharmacol., 12: 415-421.
    CrossRef  |  

  33. Jung, B., J. Chung, W. Zhou, T. Lee, M. Na and J.S. Bae, 2016. Inhibitory effects of pentacyclic triterpenoids from Astilbe rivularis on TGFBIp-induced inflammatory responses in vitro and in vivo. Chem.-Biol. Interact., 254: 179-190.
    CrossRef  |  Direct Link  |  

  34. Jung, B., H. Kang, W. Lee, H.J. Noh and Y.S. Kim et al., 2016. Anti-septic effects of dabrafenib on HMGB1-mediated inflammatory responses. BMB Rep., 49: 214-219.
    CrossRef  |  Direct Link  |  

  35. Jung, B., E.J. Yang and J.S. Bae, 2016. Suppressive effects of polyozellin on TGFBIp-mediated septic responses in human endothelial cells and mice. Nutr. Res., 36: 380-389.
    CrossRef  |  Direct Link  |  

  36. Jeong, S., S.K. Ku, G. Min, H. Choi, D.H. Park and J.S. Bae, 2016. Suppressive effects of three diketopiperazines from marine-derived bacteria on polyphosphate-mediated septic responses. Chem.-Biol. Interact., 257: 61-70.
    CrossRef  |  Direct Link  |  

  37. Chung, J., S.K. Ku, S. Lee and J.S. Bae, 2016. Suppressive effects of lysozyme on polyphosphate-mediated vascular inflammatory responses. Biochem. Biophys. Res. Commun., 474: 715-721.
    CrossRef  |  Direct Link  |  

  38. Yoon, E.K., S.K. Ku, W. Lee, S. Kwak, H. Kang, B. Jung and J.S. Bae, 2015. Antitcoagulant and antiplatelet activities of scolymoside. BMB Rep., 48: 577-582.
    CrossRef  |  Direct Link  |  

  39. Yoo, H., S.K. Ku, W. Zhou, M.S. Han, M.K. Na and J.S. Bae, 2015. Anti-septic effects of phenolic glycosides from Rhododendron brachycarpum in vitro and in vivo. J. Funct. Foods, 16: 448-459.
    CrossRef  |  Direct Link  |  

  40. Yoo, H., S.K. Ku, S.W. Kim and J.S. Bae, 2015. Early diagnosis of sepsis using serum hemoglobin subunit Beta. Inflammation, 38: 394-399.
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  41. Yang, E.J., S.K. Ku, W. Lee, K.S. Song and J.S. Bae, 2015. Inhibitory effects of polyozellin from Polyozellus multiplex on HMGB1-mediated septic responses. Inflammation Res., 64: 733-746.
    CrossRef  |  Direct Link  |  

  42. Tuan, N.Q., W. Lee, J. Oh, S. Kwak and H.G. Lee et al., 2015. Quinic acid derivatives from Salicornia herbacea alleviate HMGB1-mediated endothelial dysfunction. J. Funct. Foods, 15: 326-338.
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  43. Tuan, N.Q., W. Lee, J. Oh, R.R. Kulkarni and C. Geny et al., 2015. Flavanones and chromones from Salicornia herbacea mitigate septic lethality via restoration of vascular barrier integrity. J. Agric. Food Chem., 63: 10121-10130.
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  44. Ryu, R., U.J. Jung, Y.R. Seo, H.J. Kim and B.S. Moon et al., 2015. Beneficial effect of persimmon leaves and bioactive compounds on thrombosis. Food Sci. Biotechnol., 24: 233-240.
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  45. Park, M.S., J.W. Kim, I. Park, H.K. Lee and C. Kim et al., 2015. Characterization of ticlopidine-induced developmental and teratogenic defects in Xenopus embryos and human endothelial cells. Chem. Biol. Interact., 240: 172-178.
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  46. Oh, S.Y., J.Y. Seok, Y.S. Choi, S.H. Lee, J.S. Bae and Y.M. Lee, 2015. The histone methyltransferase inhibitor BIX01294 inhibits HIF-1α stability and angiogenesis. Molecules Cells, 38: 528-534.
    CrossRef  |  Direct Link  |  

  47. Lee, W., S.K. Ku, D.H. Na and J.S. Bae, 2015. Anti-inflammatory effects of lysozyme against HMGB1 in human endothelial cells and in mice. Inflammation, 38: 1911-1924.
    CrossRef  |  Direct Link  |  

  48. Lee, W., S.K. Ku and J.S. Bae, 2015. Antiplatelet, anticoagulant and profibrinolytic activities of baicalin. Arch. Pharm. Res., 38: 893-903.
    CrossRef  |  Direct Link  |  

  49. Lee, W., S.K. Ku and J.S. Bae, 2015. Anti-inflammatory effects of Baicalin, Baicalein and Wogonin in vitro and in vivo. Inflammation, 38: 110-125.
    CrossRef  |  Direct Link  |  

  50. Lee, W., S.K. Ku and J.S. Bae, 2015. Ameliorative effect of vicenin-2 and olymoside on TGFBIp-induced septic responses. Inflammation, 38: 2166-2177.
    CrossRef  |  Direct Link  |  

  51. Lee, W., S. Kwak, H.S. Lee, D.H. Na, Y.M. Lee and J.S. Bae, 2015. Inhibitory effect of exendin-4 on secretory group IIA phospholipase A2. Biochem. Biophys. Res. Commun., 459: 650-654.
    CrossRef  |  Direct Link  |  

  52. Lee, W., S. Kwak, E. Yun, J.H. Lee, M. Na, G.Y. Song and J.S. Bae, 2015. Anti-septic effects of new 3’-N-substituted carbazole derivatives in vitro and in vivo. Inflammation, 38: 1649-1661.

  53. Lee, W., O.K. Kwon, M.S. Han, Y.M. Lee and S.W. Kim et al., 2015. Role of moesin in HMGB1-stimulated severe inflammatory responses. Thrombosis Haemostasis, 114: 350-363.

  54. Lee, W., K.M. Kim and J.S. Bae, 2015. Ameliorative effect of aspalathin and nothofagin from rooibos (Aspalathus linearis) on HMGB1-induced septic responses in vitro and in vivo. Am. J. Chinese Med., 43: 991-1012.
    CrossRef  |  Direct Link  |  

  55. Lee, W., J. Seo, S. Kwak, E.J. Park and D.H. Na et al., 2015. A double‐chambered protein nanocage loaded with thrombin receptor agonist peptide (TRAP) and γ‐carboxyglutamic acid of protein C (PC‐Gla) for sepsis treatment. Adv. Mater., 27: 6637-6643.
    CrossRef  |  Direct Link  |  

  56. Lee, W., E.K. Yoon, K.M. Kim, D.H. Park and J.S. Bae, 2015. Antiseptic effect of vicenin-2 and scolymoside from Cyclopia subternata (Honeybush) in response to HMGB1 as a late sepsis mediator in vitro and in vivo. Can. J. Physiol. Pharmacol., 93: 709-720.
    CrossRef  |  Direct Link  |  

  57. Lee, W., E.J. Park, S. Kwak, Y. Kim, D.H. Na and J.S. Bae, 2015. PEGylated lysozymes with anti-septic effects in human endothelial cells and in mice. Biochem. Biophys. Res. Commun., 459: 662-667.
    CrossRef  |  Direct Link  |  

  58. Lee, W. and J.S. Bae, 2015. Antithrombotic and antiplatelet activities of vicenin-2. Blood Coagulation Fibrinolysis, 26: 628-634.
    CrossRef  |  Direct Link  |  

  59. Lee, W. and J.S. Bae, 2015. Antithrombotic and antiplatelet activities of orientin in vitro and in vivo. J. Funct. Foods, 17: 388-398.
    CrossRef  |  Direct Link  |  

  60. Lee, W. and J.S. Bae, 2015. Anti-inflammatory effects of aspalathin and nothofagin from rooibos (Aspalathus linearis) in vitro and in vivo. Inflammation, 38: 1502-1516.
    CrossRef  |  Direct Link  |  

  61. Lee, S.H., J.G. Jee, J.S. Bae, K.H. Liu and Y.M. Lee, 2015. A group of novel HIF‐1α inhibitors, glyceollins, blocks HIF‐1α synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding. J. Cell. Physiol., 230: 853-862.
    CrossRef  |  Direct Link  |  

  62. Lee, I.C. and J.S. Bae, 2015. Inhibitory effect of vicenin-2 and scolymoside on secretory group IIA phospholipase A2. Anim. Cells Syst., 19: 305-311.
    CrossRef  |  Direct Link  |  

  63. Lee, D.S., G.S. Jeong and J.S. Bae, 2015. Potential therapeutic properties of natural products through the expression of heme oxygenase-1. Mini-Rev. Organic Chem., 12: 455-463.
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  64. Lee, D., D. Kim, S. Lee, T. Kim and J. Kim et al., 2015. Efficient syntheses of 1,2,3-triazoloamide derivatives using solid-and solution-phase synthetic approaches. Molecules, 20: 19984-20013.
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  65. Kwon, O.K., W. Lee, S.J. Kim, Y.M. Lee and J.Y. Lee et al., 2015. In‐depth proteomics approach of secretome to identify novel biomarker for sepsis in LPS‐stimulated endothelial cells. Electrophoresis, 36: 2851-2858.
    CrossRef  |  Direct Link  |  

  66. Kwak, S., M.S. Han and J.S. Bae, 2015. Aspalathin and nothofagin from rooibos (Aspalathus linearis) inhibit endothelial protein C receptor shedding in vitro and in vivo. Fitoterapia, 100: 179-186.
    CrossRef  |  Direct Link  |  

  67. Kulkarnia, R.R., W. Lee, T.S. Jang, J. Lee and S. Kwak et al., 2015. Caffeoyl glucosides from Nandina domestica inhibit LPS-induced endothelial inflammatory responses. Bioorg. Med. Chem. Lett., 25: 5367-5371.
    CrossRef  |  Direct Link  |  

  68. Ku, S.K., W. Zhou, W. Lee, M.S. Han, M.K. Na and J.S. Bae, 2015. Anti-inflammatory effects of hyperoside in human endothelial cells and in mice. Inflammation, 38: 784-799.
    CrossRef  |  Direct Link  |  

  69. Ku, S.K., W. Lee, M. Kang and J.S. Bae, 2015. Antithrombotic activities of aspalathin and nothofagin via inhibiting platelet aggregation and FIIa/FXa. Arch. Pharm. Res., 38: 1080-1089.
    CrossRef  |  Direct Link  |  

  70. Ku, S.K., S. Kwak, Y. Kim and J.S. Bae, 2015. Aspalathin and nothofagin from rooibos (Aspalathus linearis) inhibits high glucose-induced inflammation in vitro and in vivo. Inflammation, 38: 445-455.
    CrossRef  |  Direct Link  |  

  71. Ku, S.K., M.C. Baek and J.S. Bae, 2015. Anti-inflammatory effects of methylthiouracil in vitro and in vivo. Toxicol. Applied Pharmacol., 288: 374-386.
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  72. Ku, S.K., J.H. Lee, O. Yuseok, W. Lee, G.Y. Song and J.S. Bae, 2015. Vascular barrier protective effects of 3-N-or 3-O-cinnamoyl carbazole derivatives. Bioorg. Med. Chem. Lett., 25: 4304-4307.
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  73. Ku, S.K., H.G. Lee and J.S. Bae, 2015. Inhibitory effect of baicalin, baicalein and wogonin on secretory group IIA phospholipase A2. Arch. Pharm. Res., 38: 1865-1872.
    CrossRef  |  Direct Link  |  

  74. Ku, S.K., E.K. Yoon, H.G. Lee, M.S. Han, T. Lee and J.S. Bae, 2015. Inhibitory effects of lysozyme on endothelial protein C 1receptor shedding in vitro and in vivo. BMB Rep., 48: 624-629.
    CrossRef  |  Direct Link  |  

  75. Ku, S.K. and J.S. Bae, 2015. Inhibitory effect of FXa on secretory group IIA phospholipase A2. Inflammation, 38: 987-994.
    CrossRef  |  Direct Link  |  

  76. Ku, S.K. and J.S. Bae, 2015. Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo. BMB Rep., 48: 519-524.
    CrossRef  |  Direct Link  |  

  77. Kim, D., D.J. Baek, D. Lee, K.H. Liu and J.S. Bae et al., 2015. Efficient solid-phase synthesis of 2,4-disubstituted 5-carbamoyl-thiazole derivatives using a traceless support. Tetrahedron, 71: 3367-3377.
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  78. Kang, H., S.K. Ku, B. Jung and J.S. Bae, 2015. Anti-inflammatory effects of vicenin-2 and scolymoside in vitro and in vivo. Inflammation Res., 64: 1005-1021.
    CrossRef  |  Direct Link  |  

  79. Jung, B., S.K. Ku and J.S. Bae, 2015. Ameliorative effect of methylthiouracil on TGFBIp-induced septic responses. Biochem. Biophys. Res. Commun., 463: 661-666.
    CrossRef  |  Direct Link  |  

  80. Hwang, G.H., Y.J. Jeon, H.J. Han, S.H. Park and K.M. Baek et al., 2015. Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes. J. Vet. Sci., 16: 17-23.
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  81. Hwang, G.H., J.M. Ryu, Y.J. Jeon, J. Choi and H.J. Han et al., 2015. The role of thioredoxin reductase and glutathione reductase in plumbagin-induced, reactive oxygen species-mediated apoptosis in cancer cell lines. Eur. J. Pharmacol., 765: 384-393.

  82. Baek, M.C., B. Jung, H. Kang, H.S. Lee and J.S. Bae, 2015. Novel insight into drug repositioning: Methylthiouracil as a case in point. Pharmacol. Res., 99: 185-193.
    CrossRef  |  Direct Link  |  

  83. Bae, J.S., 2015. Inhibitory effect of orientin on secretory group IIA phospholipase A2. Inflammation, 38: 1631-1638.
    CrossRef  |  Direct Link  |  

  84. Zhou, W., J. Oh, W. Lee, S. Kwak and W. Li et al., 2014. The first cyclomegastigmane rhododendroside A from Rhododendron brachycarpum alleviates HMGB1-induced sepsis. Biochim. Biophys. Acta-Gen. Subjects, 1840: 2042-2049.
    CrossRef  |  Direct Link  |  

  85. Yoo, H., S.K. Ku, Y.D. Baek and J.S. Bae, 2014. Anti-inflammatory effects of rutin on HMGB1-induced inflammatory responses in vitro and in vivo. Inflammation Res., 63: 197-206.
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  86. Yoo, H., S.K. Ku, W. Lee, S. Kwak and Y.D. Baek et al., 2014. Antiplatelet, anticoagulant, and profibrinolytic activities of cudratricusxanthone A. Arch. Pharm. Res., 37: 1069-1078.
    CrossRef  |  Direct Link  |  

  87. Yoo, H., S.K. Ku, T. Lee and J.S. Bae, 2014. Orientin inhibits HMGB1-induced inflammatory responses in HUVECs and in murine polymicrobial sepsis. Inflammation, 37: 1705-1717.
    CrossRef  |  Direct Link  |  

  88. Yoo, H., S.K. Ku, M.S. Han, K.M. Kim and J.S. Bae, 2014. Anti-septic effects of fisetin in vitro and in vivo. Inflammation, 37: 1560-1574.
    CrossRef  |  Direct Link  |  

  89. Song, M., J.Y. Hwang, M.Y. Lee, J.G. Jee and Y.M. Lee et al., 2014. In vitro inhibitory effect of piperlonguminine isolated from Piper longum on human cytochrome P450 1A2. Arch. Pharm. Res., 37: 1063-1068.
    CrossRef  |  Direct Link  |  

  90. Song, M., H. Do, O.K. Kwon, E.J. Yang and J.S. Bae et al., 2014. A comparison of the in vitro inhibitory effects of thelephoric acid and SKF-525A on human cytochrome P450 activity. Biomolecules Therapeutics, 22: 155-160.
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  91. Song, M., D. Lee, J.S. Bae, J. Lee, Y.D. Gong, T. Lee and S. Lee, 2014. Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl) piperazin-1-yl)thiazol-4-yl) pivalamide including CYP3A4-Mediated C-demethylation in human liver microsomes with high-resolution/high-accuracy tandem mass. Drug Metab. Disposition, 42: 1252-1260.

  92. Son, J., M.S. Park, I. Park, H.K. Lee and S.H. Lee et al., 2014. Pick1 modulates ephrinB1-induced junctional disassembly through an association with ephrinB1. Biochem. Biophys. Res. Commun., 450: 659-665.
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  93. Shin, S.H., S. Lee, J.S. Bae, J.G. Jee, H.J. Cha and Y.M. Lee, 2014. Thymosin beta4 regulates cardiac valve formation via endothelial-mesenchymal transformation in zebrafish embryos. Mol. Cells, 37: 330-336.
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  94. Lee, W., S.K. Ku, Y.M. Lee and J.S. Bae, 2014. Anti-septic effects of glyceollins in HMGB1-induced inflammatory responses in vitro and in vivo. Food Chem. Toxicol., 63: 1-8.
    CrossRef  |  Direct Link  |  

  95. Lee, W., S.K. Ku, T.C. Jeong, S. Lee and J.S. Bae, 2014. Ginsenosides Inhibit HMGB1-induced Inflammatory Responses in HUVECs and in murine polymicrobial sepsis. Bull. Korean Chem. Soc., 35: 2955-2962.

  96. Lee, W., S.K. Ku, S.W. Kim and J.S. Bae, 2014. Endocan elicits severe vascular inflammatory responses in vitro and in vivo. J. Cell. Physiol., 229: 620-630.
    CrossRef  |  Direct Link  |  

  97. Lee, W., S.K. Ku, E.J. Park, D.H. Na, K.M. Kim and J.S. Bae, 2014. Exendin-4 inhibits HMGB1-induced inflammatory responses in HUVECs and in murine polymicrobial sepsis. Inflammation, 37: 1876-1888.
    CrossRef  |  Direct Link  |  

  98. Lee, W., S.K. Ku, D. Lee, T. Lee and J.S. Bae, 2014. Emodin-6-O-β-D--glucoside inhibits high-glucose-induced vascular inflammation. Inflammation, 37: 306-313.
    CrossRef  |  Direct Link  |  

  99. Lee, W., S.K. Ku, B.W. Min, S. Lee, J.G. Jee, J.A. Kim and J.S. Bae, 2014. Vascular barrier protective effects of pellitorine in LPS-induced inflammation in vitro and in vivo. Fitoterapia, 92: 177-187.
    CrossRef  |  Direct Link  |  

  100. Lee, W., S.K. Ku and J.S. Bae, 2014. Vascular barrier protective effects of orientin and isoorientin in LPS-induced inflammation in vitro and in vivo. Vascular Pharmacol., 62: 3-14.
    CrossRef  |  Direct Link  |  

  101. Lee, W., S.K. Ku and J.S. Bae, 2014. Factor Xa inhibits HMGB1-induced septic responses in human umbilical vein endothelial cells and in mice. Thrombosis Haemostasis, 112: 757-769.
    CrossRef  |  Direct Link  |  

  102. Lee, W., S. Ku, H. Yoo, K. Song and J. Bae, 2014. Andrographolide inhibits HMGB1‐induced inflammatory responses in human umbilical vein endothelial cells and in murine polymicrobial sepsis. Acta Physiol., 211: 176-187.
    CrossRef  |  Direct Link  |  

  103. Lee, W., H. Yoo, S.K. Ku, S.W. Kim and J.S. Bae, 2014. Raftlin: A new biomarker in human sepsis. Inflammation, 37: 706-711.
    CrossRef  |  Direct Link  |  

  104. Lee, H.G., H.Y. Choi and J.S. Bae, 2014. Endocan as a potential diagnostic or prognostic biomarker for chronic kidney disease. Kidney Int., 86: 1079-1081.
    CrossRef  |  Direct Link  |  

  105. Kwak, S., S.K. Ku, M.S. Han and J.S. Bae, 2014. Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo. Toxicol. Applied Pharmacol., 281: 30-38.
    CrossRef  |  Direct Link  |  

  106. Kwak, S., S.K. Ku and J.S. Bae, 2014. Fisetin inhibits high-glucose-induced vascular inflammation in vitro and in vivo. Inflammation Res., 63: 779-787.
    CrossRef  |  Direct Link  |  

  107. Ku, S.K., S. Kwak, O.J. Kwon and J.S. Bae, 2014. Hyperoside inhibits high-glucose-induced vascular inflammation in vitro and in vivo. Inflammation, 37: 1389-1400.
    CrossRef  |  Direct Link  |  

  108. Ku, S.K., S. Kwak and J.S. Bae, 2014. Orientin inhibits high glucose-induced vascular inflammation in vitro and in vivo. Inflammation, 37: 2164-2173.
    CrossRef  |  Direct Link  |  

  109. Ku, S.K., M.S. Han, M.Y. Lee, Y.M. Lee and J.S. Bae, 2014. Inhibitory effects of oroxylin a on endothelial protein c receptor shedding in vitro and in vivo. BMB Rep., 47: 336-341.
    CrossRef  |  Direct Link  |  

  110. Ku, S.K., M.S. Han, G.S. Jeong and J.S. Bae, 2014. Cudratricusxanthone A inhibits endothelial protein C receptor shedding in vitro and in vivo. Anim. Cells Syst., 18: 9-16.
    CrossRef  |  Direct Link  |  

  111. Ku, S.K., M.S. Han, E.J. Park, D.H. Na and J.S. Bae, 2014. Exendin-4 inhibits endothelial protein C receptor shedding in vitro and in vivo. Pharmacol. Res., 84: 18-25.
    CrossRef  |  Direct Link  |  

  112. Ku, S.K., M.S. Han and J.S. Bae, 2014. Withaferin A is an inhibitor of endothelial protein C receptor shedding in vitro and in vivo. Food Chem. Toxicol., 68: 23-29.
    CrossRef  |  Direct Link  |  

  113. Ku, S.K., M.S. Han and J.S. Bae, 2014. Sulforaphane inhibits endothelial protein C receptor shedding in vitro and in vivo. Vascular Pharmacol., 63: 13-18.
    CrossRef  |  Direct Link  |  

  114. Ku, S.K., J.A. Kim and J.S. Bae, 2014. Vascular barrier protective effects of piperlonguminine in vitro and in vivo. Inflammation Res., 63: 369-379.
    CrossRef  |  Direct Link  |  

  115. Ku, S.K., J.A. Kim and J.S. Bae, 2014. Piperlonguminine downregulates endothelial protein C receptor shedding in vitro and in vivo. Inflammation, 37: 435-442.
    CrossRef  |  Direct Link  |  

  116. Ku, S.K., I.C. Lee, M.S. Han and J.S. Bae, 2014. Inhibitory effects of rutin on the endothelial protein C receptor shedding in vitro and in vivo. Inflammation, 37: 1424-1431.
    CrossRef  |  Direct Link  |  

  117. Ku, S.K., I.C. Lee, J.A. Kim and J.S. Bae, 2014. Anti-septic effects of pellitorine in HMGB1-induced inflammatory responses in vitro and in vivo. Inflammation, 37: 338-348.
    CrossRef  |  Direct Link  |  

  118. Ku, S.K., H. Yoo, W. Zhou, M.K. Na and J.S. Bae, 2014. Antiplatelet activities of hyperoside in vitro and in vivo. Anim. Cells Syst., 18: 204-209.
    CrossRef  |  Direct Link  |  

  119. Ku, S.K. and J.S. Bae, 2014. Antithrombotic activities of wogonin and wogonoside via inhibiting platelet aggregation. Fitoterapia, 98: 27-35.
    CrossRef  |  Direct Link  |  

  120. Ku, S.K. and J.S. Bae, 2014. Antithrombotic activities of sulforaphane via inhibiting platelet aggregation and FIIa/FXa. Pharm. Res., 37: 1454-1463.
    CrossRef  |  Direct Link  |  

  121. Ku, S.K. and J.S. Bae, 2014. Antiplatelet, anticoagulant and profibrinolytic activities of withaferin A. Vascular Pharmacol., 60: 120-126.
    CrossRef  |  Direct Link  |  

  122. Ku, S.K. and J.S. Bae, 2014. Antiplatelet and antithrombotic activities of purpurogallin in vitro and in vivo. BMB Rep., 47: 376-381.
    CrossRef  |  Direct Link  |  

  123. Jeong, G.S. and J.S. Bae, 2014. Anti-inflammatory effects of triterpenoids: Naturally occurring and synthetic agents. Mini-Rev. Organic Chem., 11: 316-329.
    Direct Link  |  

  124. Bae, J.S., W. Lee, J.O. Nam, J.E. Kim, S.W. Kim and I.S. Kim, 2014. Transforming growth factor β-induced protein promotes severe vascular inflammatory responses. Am. J. Respiratory Critical Care Med., 189: 779-786.
    CrossRef  |  Direct Link  |  

  125. Bae, J.S., W. Lee, H.N. Son, Y.M. Lee and I.S. Kim, 2014. Anti‐transforming growth factor β‐induced protein antibody ameliorates vascular barrier dysfunction and improves survival in sepsis. Acta Physiol., 212: 306-315.
    CrossRef  |  Direct Link  |  

  126. Ku, S.K., I.C. Lee and J.S. Bae, 2014. Antithrombotic activities of oroxylin A in vitro and in vivo. Arch. Pharm. Res., 37: 679-686.
    CrossRef  |  Direct Link  |  

  127. Yoo, H., H.S. Lee, W. Lee and J.S. Bae, 2013. Effects of lycopene on endothelial protein C receptor shedding in vitro and in vivo. J. Life Sci., 23: 650-656.
    CrossRef  |  Direct Link  |  

  128. Yang, E.J., S.K. Ku, W. Lee, S. Lee, T. Lee, K.S. Song and J.S. Bae, 2013. Barrier protective effects of rosmarinic acid on HMGB1‐induced inflammatory responses in vitro and in vivo. J. Cell. Physiol., 228: 975-982.
    CrossRef  |  Direct Link  |  

  129. Song, M., M. Hong, M.Y. Lee, J.G. Jee and Y.M. Lee et al., 2013. Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6. Food Chem. Toxicol., 59: 549-553.
    CrossRef  |  Direct Link  |  

  130. Ryu, R., U.J. Jung, H.J. Kim, W. Lee, J.S. Bae, Y.B. Park and M.S. Choi, 2013. Anticoagulant and antiplatelet activities of Artemisia princeps Pampanini and its bioactive components. Prev. Nutr. Food Sci., 18: 181-187.
    CrossRef  |  Direct Link  |  

  131. Lee, W., S.K. Ku, T.H. Kim and J.S. Bae, 2013. Emodin-6-O-β-d-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo. Food Chem. Toxicol., 52: 97-104.
    CrossRef  |  Direct Link  |  

  132. Lee, W., S.K. Ku, J.A. Kim, T. Lee and J.S. Bae, 2013. Inhibitory effects of epi-sesamin on HMGB1-induced vascular barrier disruptive responses in vitro and in vivo. Toxicol. Applied Pharmacol., 267: 201-208.
    CrossRef  |  Direct Link  |  

  133. Lee, W., S.K. Ku and J.S. Bae, 2013. Emodin-6-O-β-d-glucoside down-regulates endothelial protein C receptor shedding. Arch. Pharm. Res., 36: 1160-1165.
    CrossRef  |  Direct Link  |  

  134. Lee, W., H. Yoo, S.K. Ku, J.A. Kim and J.S. Bae, 2013. Anticoagulant activities of piperlonguminine in vitro and in vivo. BMB Rep., 46: 484-489.
    CrossRef  |  Direct Link  |  

  135. Lee, W., H. Yoo, J.A. Kim, S. Lee and J.G. Jee et al., 2013. Barrier protective effects of piperlonguminine in LPS-induced inflammation in vitro and in vivo. Food Chem. Toxicol., 58: 149-157.
    CrossRef  |  Direct Link  |  

  136. Lee, W., E.J. Yang, S.K. Ku, K.S. Song and J.S. Bae, 2013. Anti-inflammatory effects of oleanolic acid on LPS-induced inflammation in vitro and in vivo. Inflammation, 36: 94-102.

  137. Lee, D., Y.H. Seo, J.S. Bae, S. Lee, T.I. Lee, Y.D. Gong and T. Lee, 2013. An efficient and regioselective synthesis of 2, 3-disubstituted 6-aminoquinoxaline derivatives using alkoxylation and microwave-assisted sonogashira coupling. Notes, 34: 2522-2524.

  138. Kwon, O.J., J.S. Bae, H.Y. Lee, J.Y. Hwang, E.W. Lee, H. Ito and T.H. Kim, 2013. Pancreatic lipase inhibitory gallotannins from galla rhois with inhibitory effects on adipocyte differentiation in 3T3-L1 cells. Molecules, 18: 10629-10638.
    CrossRef  |  Direct Link  |  

  139. Ku, S.K., W. Lee, H. Yoo, C.K. Han and J.S. Bae, 2013. Inhibitory effects of epi-sesamin on endothelial protein C receptor shedding in vitro and in vivo. Inflammation Res., 62: 895-902.
    CrossRef  |  Direct Link  |  

  140. Ku, S.K., T.H. Kim, S. Lee, S.M. Kim and J.S. Bae, 2013. Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside. Food Chem. Toxicol., 53: 197-204.
    CrossRef  |  Direct Link  |  

  141. Ku, S.K., T.H. Kim and J.S. Bae, 2013. Anticoagulant activities of persicarin and isorhamnetin. Vascular Pharmacol., 58: 272-279.
    CrossRef  |  Direct Link  |  

  142. Ku, S.K., M.S. Han and J.S. Bae, 2013. Down-regulation of endothelial protein C receptor shedding by persicarin and isorhamnetin-3-O-galactoside. Thrombosis Res., 132: e58-e63.
    CrossRef  |  Direct Link  |  

  143. Ku, S.K., J.A. Kim, C.K. Han and J.S. Bae, 2013. Antithrombotic activities of epi-sesamin in vitro and in vivo. Am. J. Chin. Med., 41: 1313-1327.
    CrossRef  |  Direct Link  |  

  144. Ku, S.K., I.C. Lee, J.A. Kim and J.S. Bae, 2013. Antithrombotic activities of pellitorine in vitro and in vivo. Fitoterapia, 91: 1-8.
    CrossRef  |  

  145. Ku, S.K., I.C. Lee and J.S. Bae, 2013. Inhibitory effects of purpurogallin on the endothelial protein C receptor shedding in vitro and in vivo. J. Korean Soc. Applied Biol. Chem., 56: 519-524.
    CrossRef  |  Direct Link  |  

  146. Ku, S.K., E.J. Yang, K.S. Song and J.S. Bae, 2013. Rosmarinic acid down-regulates endothelial protein C receptor shedding in vitro and in vivo. Food Chem. Toxicol., 59: 311-315.
    CrossRef  |  Direct Link  |  

  147. Ku, S.K. and J.S. Bae, 2013. Concentration dependent anti-inflammatory effects thrombin on polyphosphate-mediated inflammatory responses in vitro and in vivo. Inflamm. Res., 62: 609-616.
    CrossRef  |  Direct Link  |  

  148. Kim, T.H., S.K. Ku and J.S. Bae, 2013. Persicarin is anti‐inflammatory mediator against HMGB1‐induced inflammatory responses in HUVECs and in CLP‐induced sepsis mice. J. Cell. Physiol., 228: 696-703.
    CrossRef  |  Direct Link  |  

  149. Kim, T.H., S.K. Ku and J.S. Bae, 2013. Anti‐inflammatory activities of isorhamnetin‐3‐O‐galactoside against HMGB1‐induced inflammatory responses in both HUVECs and CLP‐induced septic mice. J. Cell. Biochem., 114: 336-345.
    CrossRef  |  Direct Link  |  

  150. Kim, M., J. Son, M.S. Park, Y. Ji and S. Chae et al., 2013. In vivo evaluation and comparison of developmental toxicity and teratogenicity of perfluoroalkyl compounds using Xenopus embryos. Chemosphere, 93: 1153-1160.
    CrossRef  |  Direct Link  |  

  151. Choi, J.H., M.P. Nguyen, S.Y. Jung, S.M. Kwon and J.G. Jee et al., 2013. Inhibitory effect of glyceollins on vasculogenesis through suppression of endothelial progenitor cell function. Mol. Nutr. Food Res., 57: 1762-1771.
    CrossRef  |  Direct Link  |  

  152. Bae, J.S. and A.R. Rezaie, 2013. Thrombin inhibits HMGB1-mediated proinflammatory signaling responses when endothelial protein C receptor is occupied by its natural ligand. BMB Rep., 46: 544-549.
    CrossRef  |  Direct Link  |  

  153. Yang, E.J., W. Lee, S.K. Ku, K.S. Song and J.S. Bae, 2012. Anti-inflammatory activities of oleanolic acid on HMGB1 activated HUVECs. Food Chem. Toxicol., 50: 1288-1294.
    CrossRef  |  Direct Link  |  

  154. Min, K.J., J.S. Bae and T.K. Kwon, 2012. Effect of Activated Protein C (APC) on apoptosis of cancer cells. J. Life Sci., 22: 679-701.
    CrossRef  |  Direct Link  |  

  155. Lee, W.H., E.J. Yang, S.K. Ku, K.S. Song and J.S. Bae, 2012. Anticoagulant activities of oleanolic acid via inhibition of tissue factor expressions. BMB Rep., 45: 390-395.
    CrossRef  |  Direct Link  |  

  156. Lee, W., T.H. Kim, S.K. Ku, K.J. Min, H.S. Lee, T.K. Kwon and J.S. Bae, 2012. Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models. Toxicol. Applied Pharmacol., 262: 91-98.
    CrossRef  |  Direct Link  |  

  157. Lee, W., S.K. Ku, J.W. Bae and J.S. Bae, 2012. Inhibitory effects of lycopene on HMGB1-mediated pro-inflammatory responses in both cellular and animal models. Food Chem. Toxicol., 50: 1826-1833.
    CrossRef  |  Direct Link  |  

  158. Lee, W., S.K. Ku and J.S. Bae, 2012. Barrier protective effects of rutin in LPS-induced inflammation in vitro and in vivo. Food Chem. Toxicol., 50: 3048-3055.
    CrossRef  |  Direct Link  |  

  159. Kim, T.H., T. Lee, S.K. Ku and J.S. Bae, 2012. Vascular barrier protective effects of eckol and its derivatives. Bioorg. Med. Chem. Lett., 22: 3710-3712.
    CrossRef  |  Direct Link  |  

  160. Kim, T.H., S.K. Ku, T. Lee and J.S. Bae, 2012. Vascular barrier protective effects of phlorotannins on HMGB1-mediated proinflammatory responses in vitro and in vivo. Food Chem. Toxicol., 50: 2188-2195.
    CrossRef  |  Direct Link  |  

  161. Kim, T.H., S.K. Ku, I.C. Lee and J.S. Bae, 2012. Anti-inflammatory functions of purpurogallin in LPS-activated human endothelial cells. BMB Rep., 45: 200-205.
    CrossRef  |  Direct Link  |  

  162. Kim, T.H., S.K. Ku, I.C. Lee and J.S. Bae, 2012. Anti-inflammatory effects of kaempferol-3-O-sophoroside in human endothelial cells. Inflamm. Res., 61: 217-224.
    CrossRef  |  Direct Link  |  

  163. Kim, T.H., S.K. Ku and J.S. Bae, 2012. Inhibitory effects of kaempferol-3-O-sophoroside on HMGB1-mediated proinflammatory responses. Food Chem. Toxicol., 50: 1118-1123.
    CrossRef  |  Direct Link  |  

  164. Kim, T.H., S.K. Ku and J.S. Bae, 2012. Effects of (-)-epigallocatechin gallate on HMGB1 and interleukin-1β-mediated barrier disruption in human endothelial cells. J. Korean Soc. Applied Biol. Chem., 55: 165-173.
    CrossRef  |  Direct Link  |  

  165. Kim, T.H., S.K. Ku and J.S. Bae, 2012. Antithrombotic and profibrinolytic activities of eckol and dieckol. J. Cell. Biochem., 113: 2877-2883.
    CrossRef  |  Direct Link  |  

  166. Kim, T.H. and J.S. Bae, 2012. Inhibitory effects of lycopene on the expression of pro-inflammatory genes in human vascular endothelial cells. Korean J. Food Preserv., 19: 287-293.
    CrossRef  |  Direct Link  |  

  167. Kim, D.C., S.K. Ku, W. Lee and J.S. Bae, 2012. Barrier protective activities of curcumin and its derivative. Inflamm. Res., 61: 437-444.
    CrossRef  |  Direct Link  |  

  168. Kim, D.C., S.K. Ku and J.S. Bae, 2012. Anticoagulant activities of curcumin and its derivative. BMB Rep., 45: 221-226.
    CrossRef  |  Direct Link  |  

  169. Bae, J.S., W. Lee and A.R. Rezaie, 2012. Polyphosphate elicits pro-inflammatory responses that are counteracted by activated protein C in both cellular and animal models. J. Thrombosis Haemostasis, 10: 1145-1151.
    CrossRef  |  Direct Link  |  

  170. Bae, J.S., H.S. Lee, H.Y. Lee, B.H. Yoo, T. Kim, Y.H. Kim and T.H. Kim, 2012. Evaluation of acetylcholinesterase inhibitory and antioxidative activities of Rhus javanica. Korean J. Food Preserv., 19: 751-756.
    CrossRef  |  Direct Link  |  

  171. Bae, J.S., 2012. Role of high mobility group box 1 in inflammatory disease: Focus on sepsis. Arch. Pharm. Res., 35: 1511-1523.
    CrossRef  |  Direct Link  |  

  172. Bae, J.S., 2012. Effects of lower concentration thrombin on high-mobility group box 1 protein-mediated inflammatory responses. Inflammation, 35: 1078-1086.
    CrossRef  |  Direct Link  |  

  173. Bae, J.S., 2012. Barrier protective activities of phloroglucinol on lipopolysaccharide (LPS)-induced barrier disruption in human endothelial cells. Inflammation, 35: 920-926.
    CrossRef  |  Direct Link  |  

  174. Bae, J.S. and T.H. Kim, 2012. Enzymatic transformation of caffeic acid with enhanced cyclooxygenase-2 inhibitory activity. Bioorg. Med. Chem. Lett., 22: 793-796.
    CrossRef  |  Direct Link  |  

  175. Lee, I.C., J.S. Bae, T. Kim, O.J. Kwon and T.H. Kim, 2011. Polyphenolic constituents from the aerial parts of Thymus quinquecostatus var. japonica collected on Ulleung Island. J. Korean Soc. Applied Biol. Chem., 54: 811-816.
    CrossRef  |  Direct Link  |  

  176. Kim, D.C., W. Lee and J.S. Bae, 2011. Vascular anti-inflammatory effects of curcumin on HMGB1-mediated responses in vitro. Inflamm. Res., 60: 1161-1168.
    CrossRef  |  Direct Link  |  

  177. Bae, J.W. and J.S. Bae, 2011. Barrier protective effects of lycopene in human endothelial cells. Inflamm. Res., 60: 751-758.
    CrossRef  |  Direct Link  |  

  178. Bae, J.S., 2011. Inhibitory effect of thrombin on the expression of secretory group IIA phospholipase A2. J. Cell. Biochem., 112: 2502-2507.
    CrossRef  |  Direct Link  |  

  179. Bae, J.S., 2011. Antithrombotic and profibrinolytic activities of phloroglucinol. Food Chem. Toxicol., 49: 1572-1577.
    CrossRef  |  Direct Link  |  

  180. Bae, J.S. and T.H. Kim, 2011. Pancreatic lipase inhibitory and antioxidant activities of Zingiber officinale extracts. Korean J. Food Preserv., 18: 390-396.
    CrossRef  |  Direct Link  |  

  181. Bae, J.S. and A.R. Rezaie, 2011. Activated protein c inhibits high mobility group box 1 signaling in endothelial cells. Blood, 118: 3952-3959.
    CrossRef  |  Direct Link  |  

  182. Kim, T.H. and J.S. Bae, 2010. Inhibitory effects of antithrombin on the expression of secretory group IIA phospholipase A2 in endothelial cells. BMB Rep., 43: 604-608.
    CrossRef  |  Direct Link  |  

  183. Kim, T.H. and J.S. Bae, 2010. Ecklonia cava extracts inhibit lipopolysaccharide induced inflammatory responses in human endothelial cells. Food Chem. Toxicol., 48: 1682-1687.
    CrossRef  |  Direct Link  |  

  184. Hong, J.Y., S.R. Shin, M.J. Bae, J.S. Bae and I.C. Lee et al., 2010. Pancreatic lipase inhibitors isolated from the leaves of cultivated mountain ginseng (Panax ginseng). Korean J. Food Preserv., 17: 727-732.
    Direct Link  |  

  185. Cho, C.H., J.S. Bae and Y.U. Kim, 2010. 5α-reductase inhibitory components as antiandrogens from herbal medicine. J. Acupuncture Meridian Stud., 3: 116-118.
    CrossRef  |  Direct Link  |  

  186. Bae, J.S., Y.U. Kim and M.K. Park, 2010. A study on the concentration of aflatoxin B1 in granule and globular types of herbal medicines. J. Environ. Sci. Int., 19: 209-215.
    CrossRef  |  Direct Link  |  

  187. Bae, J.S., L. Yang and A.R. Rezaie, 2010. Factor X/Xa elicits protective signaling responses in endothelial cells directly via PAR-2 and indirectly via endothelial protein C receptor-dependent recruitment of PAR-1. J. Biol. Chem., 285: 34803-34812.
    CrossRef  |  Direct Link  |  

  188. Bae, J.S., J.P. Park, Y.U. Kim and M.K. Park, 2010. Concentration of heavy metals in granule, globular and liquid types of herbal medicines. KSBB J., 25: 91-96.
    Direct Link  |  

  189. Bae, J.S., I.S. Kim and A.R. Rezaie, 2010. Thrombin down-regulates the TGF-β-mediated synthesis of collagen and fibronectin by human proximal tubule epithelial cells through the EPCR-dependent activation of PAR-1. J. Cell. Physiol., 225: 233-239.
    CrossRef  |  Direct Link  |  

  190. Bae, J.S. and M.K. Park, 2010. Effect of thrombin on the TNF-α induced IL-6 production in HUVECs. KSBB J., 25: 11-17.
    Direct Link  |  

  191. Bae, J.S. and A.R. Rezaie, 2010. Thrombin upregulates the angiopoietin-Tie2 Axis: endothelial protein C receptor occupancy prevents the thrombin mobilization of angiopoietin 2 and P-selectin from Weibel-Palade bodies. J. Thrombosis Haemostasis, 8: 1107-1115.
    CrossRef  |  Direct Link  |  

  192. Bae, J.S. and A.R. Rezaie, 2010. Thrombin and activated protein C inhibit the expression of secretory group IIA phospholipase A2 in the TNF-α-activated endothelial cells by EPCR and PAR-1 dependent mechanisms. Thrombosis Res., 125: e9-e15.
    CrossRef  |  Direct Link  |  

  193. Javed, A., F. Afzal, J.S. Bae, S. Gutierrez and K. Zaidi et al., 2009. Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation. Cells Tissues Org., 189: 133-137.
    CrossRef  |  Direct Link  |  

  194. Ha, J.L., J.S. Bae, M.K. Park, Y.U. Kim and S.H. Ha et al., 2009. Quantitative analysis of carotenoids in carrot cultivars produced in Korea. J. Environ. Sci. Int., 18: 1135-1141.
    CrossRef  |  Direct Link  |  

  195. Bae, J.S., Y.U. Kim, M.K. Park and A.R. Rezaie, 2009. Concentration dependent dual effect of thrombin in endothelial cells via Par-1 and Pi3 kinase. J. Cell. Physiol., 219: 744-751.
    CrossRef  |  Direct Link  |  

  196. Bae, J.S., M.K. Park and S.W. Park, 2009. Effect of soluble EPCR on the anti-inflammatory effects by activated protein C. Korean Chem. Eng. Res., 47: 501-505.
    Direct Link  |  

  197. Bae, J.S. and T.H. Kim, 2009. Acetylcholinesterase inhibitory and antioxidant properties of Aster yomena extract. Korea J. Herbol., 24: 121-126.
    Direct Link  |  

  198. Bae, J.S. and A.R. Rezaie, 2009. Thrombin inhibits nuclear factor κB and RhoA pathways in cytokine-stimulated vascular endothelial cells when EPCR is occupied by protein C. Thrombosis Haemostasis, 101: 513-520.
    Direct Link  |  

  199. Bae, J.S. and A.R. Rezaie, 2009. Mutagenesis studies toward understanding the intracellular signaling mechanism of antithrombin. J. Thrombosis Haemostasis, 7: 803-810.
    CrossRef  |  Direct Link  |  

  200. Rezaie, A.R., J.S. Bae, C. Manithody, S.H. Qureshi and L. Yang, 2008. Protein Z-dependent protease inhibitor binds to the C-terminal domain of protein Z. J. Biol. Chem., 283: 19922-19926.
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  201. Qureshi, S.H., L. Yang, C. Manithody, J.S. Bae and A.R. Rezaie, 2008. Functional properties and active-site topographies of factor X Gla- and prothrombin Gla-domain chimeras of activated protein C. Biochimica Biophysica Acta (BBA)-Gen. Subj., 1780: 1080-1086.
    CrossRef  |  Direct Link  |  

  202. Qureshi, S.H., C. Manithody, J.S. Bae, L. Yang and A.R. Rezaie, 2008. Autolysis loop restricts the specificity of activated protein C: Analysis by FRET and functional assays. Biophys. Chem., 134: 239-245.
    CrossRef  |  Direct Link  |  

  203. Monteiro, R.Q., A.R. Rezaie, J.S. Bae, E. Calvo, J.F. Andersen and I. Francischetti, 2008. Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite. Protein Sci., 17: 146-153.
    CrossRef  |  Direct Link  |  

  204. Javed, A., J.S. Bae, F. Afzal, S. Gutierrez and J. Pratap et al., 2008. Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal. J. Biol. Chem., 283: 8412-8422.
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  205. Bae, J.S., L. Yang and A.R. Rezaie, 2008. Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells. J. Thrombosis Haemostasis, 6: 954-961.
    CrossRef  |  Direct Link  |  

  206. Bae, J.S. and A.R. Rezaie, 2008. Protease Activated Receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand. Thrombosis Haemostasis, 100: 101-109.
    CrossRef  |  PubMed  |  Direct Link  |  

  207. Yang, L., J.S. Bae, C. Manithody and A.R. Rezaie, 2007. Identification of a specific exosite on activated protein C for interaction with protease-activated receptor 1. J. Biol. Chem., 282: 25493-25500.
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  208. Bae, J.S., S. Gutierrez, R. Narla, J. Pratap and R. Devados et al., 2007. Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation. J. Cell. Biochem., 100: 434-449.
    CrossRef  |  Direct Link  |  

  209. Bae, J.S., L. Yang, C. Manithody and A.R. Rezaie, 2007. The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells. Blood, 110: 3909-3916.
    CrossRef  |  Direct Link  |  

  210. Bae, J.S., L. Yang, C. Manithody and A.R. Rezaie, 2007. Engineering a disulfide bond to stabilize the calcium-binding loop of activated protein C eliminates its anticoagulant but not its protective signaling properties. J. Biol. Chem., 282: 9251-9259.
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  211. Bae, J.S., L. Yang and A.R. Rezaie, 2007. Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells. Proc. Natl. Acad. Sci., 104: 2867-2872.
    CrossRef  |  Direct Link  |  

  212. Lee, B.H., J.S. Bae, R.W. Park, J.E. Kim, J.Y. Park and I.S. Kim, 2006. βig-h3 triggers signaling pathways mediating adhesion and migration of vascular smooth muscle cells through αvβ5 integrin. Exp. Mol. Med., 38: 153-161.
    CrossRef  |  Direct Link  |  

  213. Park, S.W., J.S. Bae, K.S. Kim, S.H. Park and B.H. Lee et al., 2004. Beta ig-h3 promotes renal proximal tubular epithelial cell adhesion, migration and proliferation through the interaction with α3β1 integrin. Exp. Mol. Med., 36: 211-219.
    CrossRef  |  Direct Link  |  

  214. Ha, S.W., H.J. Kim, J.S. Bae, G.H. Jeong and S.C. Chung et al., 2004. Elevation of urinary βig-h3, transforming growth factor-β-induced protein in patients with type 2 diabetes and nephropathy. Diabetes Res. Clin. Pract., 65: 167-173.
    CrossRef  |  PubMed  |  Direct Link  |  

  215. Lee, S.H., J.S. Bae, S.H. Park, B.H. Lee and R.W. Park et al., 2003. Expression of TGF-β-induced matrix protein βig-h3 is up-regulated in the diabetic rat kidney and human proximal tubular epithelial cells treated with high glucose. Kidney Int., 64: 1012-1021.
    CrossRef  |  Direct Link  |  

  216. Ha, S.W., J.S. Bae, H.J. Yeo, S.H. Lee and J.Y. Choi et al., 2003. TGF-β-induced protein βig-h3 is upregulated by high glucose in vascular smooth muscle cells. J. Cell. Biochem., 88: 774-782.
    CrossRef  |  Direct Link  |  

  217. Ha, S.W., H.J. Yeo, J.S. Bae, S.C. Chung and J.G. Kim et al., 2003. Effect and mechanism of high glucose level on the expression of an adhesion protein, βig-h3 and cellular function in endothelial cells. J. Korean Diabetes Assoc., 27: 323-331.
    Direct Link  |  

  218. Ha, S.W., G.H. Jung, H.J. Yeo, J.S. Bae and S.H. Lee et al., 2002. Effect of transforming growth factor-induced gene product, βig-h3 on proliferation, migration and adhesion of aortic smooth muscle cells cultured in high glucose. J. Korean Diabetes Assoc., 26: 286-295.
    Direct Link  |  

  219. Bae, J.S., S.H. Lee, J.E. Kim, J.Y. Choi and R.W. Park et al., 2002. βig-h3 supports keratinocyte adhesion, migration and proliferation through α3β1 integrin. Biochem. Biophys. Res. Commun., 294: 940-948.
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