Dr. Ying Zhang

Associate Professor
Harbin Medical University, China


Highest Degree
Ph.D. in Pharmacology from Harbin Medical University, China

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Area of Interest:

Pharmacology and Toxicology
Cardiology
Electrical Remodeling
MicroRNA Downregulation
Physiology

Selected Publications

  1. Zhang, Y., L. Sun, L. Xuan, Z. Pan and K. Li, et al., 2016. Reciprocal changes of circulating long non-coding RNAs ZFAS1 and CDR1AS predict acute myocardial infarction. Sci. Rep., .
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  2. Yin, H., T. Liu, Y. Zhang and B. Yang, 2016. Caveolin proteins: a molecular insight into disease. Front. Med., 2016: 1-8.
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  3. Liu, X., Y. Zhang, W. Du, H. Liang and H. He, et al., 2016. MiR-223-3p as a novel MicroRNA regulator of expression of voltage-gated K+ channel Kv4. 2 in acute myocardial infarction. Cell. Physiol. Biochem., 39: 102-114.
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  4. Liang, P., K. Sallam, H. Wu, Y. Li and I. Itzhaki, et al., 2016. Patient-specific and genome-edited induced pluripotent stem cell-derived cardiomyocytes elucidate single-cell phenotype of brugada syndrome. J. Am. Coll. Cardiol., 68: 2086-2096.
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  5. Yang, L., B. Cai, R. Wang, W. Du and Y. Zhang, et al., 2014. Gusongning reduced the susceptibility of orchidectomized rats to arrhythmias in infarcted myocardium. Int. J. Cardiol., 172: e162-e164.
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  6. Sun, L., Y. Zhang, Y. Zhang, Y. Gu and L. Xuan, et al., 2014. Expression profile of long non-coding RNAs in a mouse model of cardiac hypertrophy. Int. J. Cardiol., 177: 73-75.
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  7. Liang, H., C. Xu, Z. Pan, Y. Zhang and Z. Xu, et al., 2014. The antifibrotic effects and mechanisms of microRNA-26a action in idiopathic pulmonary fibrosis. Mol. Ther., 22: 1122-1133.
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  8. Li, C., X. Li, X. Gao, R. Zhang and Y. Zhang, et al., 2014. MicroRNA-328 as a regulator of cardiac hypertrophy. Int. J. Cardiol., 173: 268-276.
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  9. Hu, C.W., Q. Li, Y. Zhang, Y.H. Li and H.C. Jiang, et al., 2014. Bone morphogenetic protein-4 induces upregulation of Cav3. 1 Ca2+ channels in HL-1 atrial myocytes. Pflugers Arch. Eur. J. Physiol., 466: 2049-2057.
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  10. He, H., X. Liu, L. Lv, H. Liang and B. Leng, et al., 2014. Calcineurin suppresses AMPK-dependent cytoprotective autophagy in cardiomyocytes under oxidative stress. Cell Death Dis., 5: e997-e997.
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  11. Zhang, Y., Z. Dong, L. Jin, K. Zhang and X. Zhao, et al., 2013. Arsenic trioxide-induced hERG K+ channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression. Biochem. Pharmacol., 85: 59-68.
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  12. Zhang, Y., R. Wang, W. Du, S. Wang and L. Yang, et al., 2013. Downregulation of miR-151-5p contributes to increased susceptibility to arrhythmogenesis during myocardial infarction with estrogen deprivation. PloS one, .
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  13. Shan, H., Y. Zhang, B. Cai, X. Chen and Y. Fan, et al., 2013. Upregulation of microRNA-1 and microRNA-133 contributes to arsenic-induced cardiac electrical remodeling. Int. J. Cardiol., 167: 2798-2805.
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  14. Liang, H., X. Li, L. Wang, S. Yu and Z. Xu, et al., 2013. MicroRNAs contribute to promyelocyte apoptosis in As2O3-treated APL cells. Cell. Physiol. Biochem., 32: 1818-1829.
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  15. Li, Q., Y. Zhang, Y. Sheng, R. Huo and B. Sun, et al., 2012. Large T-antigen up-regulates Kv4. 3 K+ channels through Sp1, and Kv4. 3 K+ channels contribute to cell apoptosis and necrosis through activation of calcium/calmodulin-dependent protein kinase II. Biochem. J., 441: 859-869.
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  16. Zhang, Y., X. Sun, J. Wang, Y. Lu, B. Yang and Z. Wang, 2011. Potential therapeutic value of antioxidants for abnormal prolongation of QT interval and the associated arrhythmias in a rabbit model of diabetes. Cell. Physiol. Biochem., 28: 97-102.
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  17. Zhang, Y., D. Dong and B. Yang, 2011. Atrial remodeling in atrial fibrillation and the association of microRNAs network with atrial fibrillation. Sci, China Life Sci., 54: 1097-1102.

  18. Bai, Y.L., H.B. Liu, B. Sun, Y. Zhang and Q. Li, et al., 2011. HIV Tat protein inhibits hERG K+ channels: a potential mechanism of HIV infection induced LQTs. J. Mol. Cell. Cardiol., 51: 876-880.
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  19. Lu, Y., Y. Zhang, N. Wang, Z. Pan and X. Gao, et al., 2010. MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation. Circ., 122: 2378-2387.
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  20. Shan, H., Y. Zhang, Y. Lu, Y. Zhang and Z. Pan, et al., 2009. Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines. Cardiovasc. Res., 83: 465-472.
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  21. Bai, Y., J. Wang, H. Shan, Y. Lu and Y. Zhang, et al., 2008. Sphingolipid metabolite ceramide causes metabolic perturbation contributing to HERG K+ channel dysfunction. Cell. Physiol. Biochem., 20: 429-440.
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  22. Yang, B., H. Lin, J. Xiao, Y. Lu and X. Luo et al., 2007. The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nature Med., 13: 486-491.
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