Dr. Jinhui Wang

Professor
Chinese Academy of Sciences, China


Highest Degree
Ph.D. in Neurosciences from Shanghai Institute of Physiology, China

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Area of Interest:

Pharmacology and Toxicology
Signaling Pathways
Brain Research
Cell Cultures
Neuroscience

Selected Publications

  1. Yan, F., G. Zilong, C. Pin, H. Li and W. Jin-Hui, 2016. Coordinated plasticity between barrel cortical glutamatergic and GABAergic neurons during associative memory. Neural Plasticity, 10.1155/2016/5648390.
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  2. Ma, K., X. Aiping, C. Shan, S. Meng-Ru, X. Yuan-Chao and W. Jin-Hui, 2016. Impaired GABA synthesis, uptake and release are associated with depression-like behaviors induced by chronic mild stress. Transl. Psychiatry, 10.1038/tp.2016.181.
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  3. Ma, K., G. Li, X. Aiping, C. Shan and W. Jin-Hui, 2016. Molecular mechanism for stress-induced depression assessed by sequencing miRNA and mRNA in medial prefrontal cortex. PLoS One, 10.1371/journal.pone.0159093.
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  4. Guan-Yan, W., Z. Zhao-Ming, M. Ke, C. Shan and W. Jin-Hui, 2016. Glucocorticoid induces incoordination between glutamatergic and GABAergic neurons in the amygdala. PLoS One, 10.1371/journal.pone.0166535.
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  5. Gao, Z., C. Lei, F. Ruicheng, L. Wei and W. Jin-Hui, 2016. Associations of unilateral whisker and olfactory signals induce synapse formation and memory cell recruitment in bilateral barrel cortices: Cellular mechanism for unilateral training toward bilateral memory. Front. Cell. Neurosci., 10.3389/fncel.2016.00285.
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  6. Xu, A., C. Shan and W. Jin-Hui, 2015. Incoordination among subcellular compartments is associated to depression-like behavior induced by chronic mild stress. Int. J. Neuropsychopharmacol. 10.1093/ijnp/pyv122.
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  7. Wen, B., Q. Hao, F. Jing, G. Rong-Jing and W. Jin-Hui et al., 2015. A portion of inhibitory neurons in human TLE are functionally upregulated: An endogenous mechanism for seizure termination. CNS Neurosci. Ther., 21: 204-214.
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  8. Wang, D., Z. Jun, G. Zilong, C. Na and W. Jin-Hui, 2015. Neurons in the barrel cortex turn into processing whisker and odor signals: A cellular mechanism for the storage and retrieval of associative signals. Front. Cell. Neurosci., 10.3389/fncel.2015.00320.
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  9. Lei, Z., L. Bei and W. Jin-Hui, 2015. Reward memory relieves anxiety-related behavior through synaptic strengthening and protein kinase C in dentate gyrus. Hippocampus, 26: 502-516.
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  10. Jin-Hui W., L. Wei and W. Bo, 2015. Neuron-specific mechanisms for epilepsy self-termination. Mol. Cell. Epilepsy, .
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  11. Jin-Hui W and C. Shan, 2015. Multi-target therapy for subcellular incompatibility in brain disorders. Brain Disord. Ther., 10.4172/2168-975X.1000200.
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  12. Huang, L., Z. Shidi, L. Wei, G. Sudong, Z. Yan and W. Jin-Hui, 2015. Acidosis-induced dysfunction of cortical GABAergic neurons through astrocyte-related excitotoxicity. PLoS One, 10.1371/journal.pone.0140324.
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  13. Yang, Z and W. Jin-Hui, 2014. Essential role of axonal VGSC inactivation in time-dependent deceleration and unreliability of spike propagation at cerebellar Purkinje cells. Mol. Brain, 10.1186/1756-6606-7-1.
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  14. Wang, M., C. Na and W. Jin-Hui, 2014. The coupling features of electrical synapses modulate neuronal synchrony in hypothalamic superachiasmatic nucleus. Brain Res., 1550: 9-17.
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  15. Sha, L., W. Xiaofeng, Y. Yuan, W. Bo and W. Jin-Hui et al., 2014. Notch signaling activation promotes seizure activity in temporal lobe epilepsy. Mol. Neurobiol., 49: 633-644.
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  16. Lu, W., W. Bo, Z. Fengyu and W. Jin-Hui, 2014. Voltage-independent sodium channels emerge for an expression of activity-induced spontaneous spikes in GABAergic neurons. Mol. Brain, 10.1186/1756-6606-7-38.
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  17. Liu, B., F. Jing and W. Jin-Hui, 2014. Protein kinase C is essential for kainate-induced anxiety-like behavior and glutamatergic synapse upregulation in prefrontal cortex. CNS Neurosci. Ther., 20: 982-990.
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  18. Ge, R., Q. Hao, C. Na and W. Jin-Hui, 2014. Input-dependent subcellular localization of spike initiation between soma and axon at cortical pyramidal neurons. Mol. Brain, 10.1186/1756-6606-7-26.
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  19. Zhang, G., G. Zhilong, G. Sudong, Z. Yan and W. Jin-Hui, 2013. Upregulation of excitatory neurons and downregulation of inhibitory neurons in barrel cortex are associated with loss of whisker inputs. Mol. Brain, 10.1186/1756-6606-6-2.
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  20. Yang, Z and W. Jin-Hui, 2013. Frequency-dependent reliability of spike propagation is function of axonal voltage-gated sodium channels in cerebellar Purkinje cells. Cerebellum, 12: 862-869.
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  21. Jiang, B., W. Wei, W. Fang, H. Zhuang-Li and W. Jin-Hui et al., 2013. The stability of NR2B in the nucleus accumbens controls behavioral and synaptic adaptations to chronic stress. Biol. Psychiatry, 74: 145-155.
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  22. Zhao, J., W. Dangui and W. Jin-Hui, 2012. Barrel cortical neurons and astrocytes coordinately respond to an increased whisker stimulus frequency. Mol. Brain, 10.1186/1756-6606-5-12.
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  23. Zhang, F., L. Bei, L. Zhuofan and W. Jin-Hui, 2012. mGluR activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: Implication for anxiety-like behavior in DAB/2 mice. Mol. Bain, 10.1186/1756-6606-5-20.
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  24. Yu, J., Q. Hao and W. Jin-Hui, 2012. Upregulation of transmitter release probability improves a conversion of synaptic analogue signals into neuronal digital spikes. Mol. Brain, 10.1186/1756-6606-5-26.
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  25. Ye, B., H. Li, G. Zilong, C. Ping and W. Jin-Hui et al., 2012. The functional upregulation of piriform cortex is associated with cross-modal plasticity in loss of whisker tactile inputs. PLoS One, 10.1371/journal.pone.0041986.
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  26. Yu, J., Q. Hao, C. Na and W. Jin-Hui, 2011. Quantal glutamate release is essential for reliable neuronal encodings in cerebral networks. PloS One, 10.1371/journal.pone.0025219.
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  27. Rongjing, G.e., Q. Hao and W. Jin-Hui, 2011. Physiological synaptic signals initiate sequential spikes at soma of cortical pyramidal neurons. Mol. Brain, 10.1186/1756-6606-4-19.
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  28. Ni, H., H. Li, C. Na, L. Dongbo and W. Jin-Hui et al., 2010. Upregulation of barrel GABAergic neurons is associated with cross-modal plasticity in olfactory deprivation. PLoS One, 10.1371/journal.pone.0013736.
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  29. Li, F., Z. Yang, Y. Lu, D. Yin, J.H. Wang and R. He, 2010. Malondialdehyde suppresses cerebralfunction by breaking homeostasis between excitation and inhibition in turtle trachemys scripta. PLoS One, 10.1371/journal.pone.0015325.
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  30. Huang, L., C. Na, G. Ming, G. Sudong, Z. Yan and W. Jin-Hui, 2010. Ca2+ and acidosis initiate the dysfunction of cortical GABAergic neurons synergistically during ischemia. Biochem. Biophys. Res. Commun., 394: 709-714.
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  31. Chen, N., Y. Jiandong, Q. Hao and W. Jin-Hui, 2010. Axons amplify somatic incomplete spikes into uniform amplitudes in mouse cortical pyramidal neurons. PLoS One, 10.1371/journal.pone.0011868.
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  32. Wang, Q., L. Xiuping, G. Rongjing, G. Sudong, Z. Yan and W. Jin-Hui, 2009. The postnatal development of intrinsic properties and spike encoding at cortical GABAergic neurons. Biochem. Biophys. Res. Commun., 378: 706-710.
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  33. Ge, R., C. Na and W. Jin-Hui, 2009. Real-time neuronal homeostasis by coordinating VGSC intrinsic properties. Biochem. Biophys. Res. Commun., 387: 585-589.
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  34. 10. Qi, Y., H. Li, N. Hong, Z. Xin and W. Jin-Hui et al., 2009. Intracellular Ca2+ regulates spike encoding at cortical GABAergic neurons and cerebellar Purkinje cells differently. Biochem. Biophys. Res. Commun., 381: 129-133.
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  35. Zhao, S., C. Na and W. Jin-Hui, 2008. Ischemia deteriorates the spike encoding of rat cerebellar Purkinje cells by raising intracellular Ca2+. Biochem. Biophys. Res. Commun., 366: 401-407.
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  36. Jin-Hui, W., J. Wei, X. Chen, J. Yu, N. Chen and J. Shi, 2008. The gain and fidelity of transmission patterns at cortical excitatory unitary synapses improves spike encoding. J. Cell Sci., 121: 2951-2960.
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  37. Chen, N., C. Xin and W. Jin-Hui, 2008. Homeostasis by coordination of subcellular compartment plasticity improves spike encoding. J. Cell Sci., 121: 2961-2971.
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  38. Guan, S., M. Shanfeng, Z. Yan, G. Rongjin, W. Qiyi and W. Jin-Hui, 2006. The intrinsic mechanisms underlying the maturation of programming sequential spikes at cerebellar Purkinje cells. Biochem. Biophys. Res. Commun., 345: 175-180.
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  39. Guan, S., M. Shanfeng, Z. Yan and W. Jin-Hui, 2006. The postnatal development of refractory periods and threshold potentials at cerebellar Purkinje neurons. Brain Res., 1097: 59-64.
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  40. Chen, N., Z. Yan, G. Xin, G. Sudong and W. Jin-Hui, 2006. Sodium channel- mediated intrinsic mechanisms underlyingthe differences of spike programming among GABAergic neurons. Biochem. Biophys. Res. Commun., 346: 281-287.
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  41. Chen, N., C. Xin, Y. Jiandong and W. Jin-Hui, 2006. After-hyperpolarization improves spike programming through lowering threshold potentials and refractory periods mediated by voltage-gated sodium channels. Biochem. Biophys. Res. Commun., 346: 938-945.
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  42. Chen, N., C. Shuli, W. Yingliang and W. Jinhui, 2006. The refractory periods and threshold potentials of sequential spikes measured by whole-cell recording. Biochem. Biophys. Res. Commun., 340: 151-157.
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  43. Zhang, M., H.Y.Z. Fen-S, X. Zuoping and W. Jin-Hui, 2004. Calcium signal-dependent multigrade-plasticity of neuronal excitability developed postnatally. J. Neurobiol., 61: 277-287.
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  44. Wei, J., Z. Mei, Z. Yan and W. Jin-Hui, 2004. Ca2+-calmodulin signalling pathway up-regulates GABA synaptic transmission through cytoskeleton-mediated mechanisms. Neurosci., 127: 637-647.
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  45. Jin-Hui, W and Z. Mei, 2004. Differential modulation of glutamatergic and cholinergic synapses by calcineurin in hippocampal CA1 fast-spiking interneurons. Brain Res., 1004: 125-135.
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  46. Jin-Hui, W., 2003. Short-term cerebral ischemia causes the dysfunction of interneurons and more excitation of pyramidal neurons in rats. Brain Res. Bull., 60: 53-58.
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  47. Jin-Hui, W and K. Paul, 2001. Calcium-calmodulin signalling pathway up-regulates glutamatergic synaptic function in non-pyramidal, fast spiking rat hippocampal CA1 neurons. J. Physiol., 533: 407-422.
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