Dr. Dan Li

Researcher
University of Oxford, United State of America

Highest Degree
Ph.D. in Medical Science from Chonbuk National University, Republic of Korea

My URL
https://livedna.org/86.25035

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Area of Interest:

Biomedical Sciences
Cardiovascular Research
Gene Therapy
Physiological Sciences
Heart Failure

Selected Publications

  1. Liu, K., D. Li, G. Hao, D. McCaffary and O. Neely et al., 2018. Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity. JCI Insight, Vol. 3. 10.1172/jci.insight.98694.
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  2. Shanks, J., N. Herring, E. Johnson, K. Liu, D. Li and D.J. Paterson, 2017. Overexpression of sarcoendoplasmic reticulum calcium ATPase 2a promotes cardiac sympathetic neurotransmission via abnormal endoplasmic reticulum and mitochondria Ca2+ regulation. Hypertension, 69: 625-632.
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  3. Pijacka, W., F.D. McBryde, P.J. Marvar, G.S. Lincevicius and A.P. Abdala et al., 2016. Carotid sinus denervation ameliorates renovascular hypertension in adult Wistar rats. J. Physiol., 594: 6255-6266.
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  4. Li, D. and D.J. Paterson, 2016. Cyclic nucleotide regulation of cardiac sympatho‐vagal responsiveness. J. Physiol., 594: 3993-4008.
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  5. Buttgereit, J., J. Shanks, D. Li, G. Hao and A. Athwal et al., 2016. C-type natriuretic peptide and NPR-B signalling inhibits cardiac sympathetic neurotransmission and autonomic function. Cardiovascular Res., 112: 637-644.
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  6. Lu, C.J., G. Hao, N. Nikiforova, H.E. Larsen and K. Liu et al., 2015. CAPON modulates neuronal calcium handling and cardiac sympathetic neurotransmission during dysautonomia in hypertension. Hypertension, 65: 1288-1297.
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  7. Li, D., C.J. Lu, G. Hao, H. Wright and L. Woodward et al., 2015. Efficacy of B-type natriuretic peptide is coupled to phosphodiesterase 2A in cardiac sympathetic neurons. Hypertension, 66: 190-198.
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  8. Shanks, J., S. Manou-Stathopoulou, C.J. Lu, D. Li, D.J. Paterson and N. Herring, 2013. Cardiac sympathetic dysfunction in the prehypertensive spontaneously hypertensive rat. Am. J. Physiol. Heart Circ. Physiol., 305: H980-H986.
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  9. Li, D., N. Nikiforova, C.J. Lu, K. Wannop and M. McMenamin et al., 2013. Targeted neuronal nitric oxide synthase transgene delivery into stellate neurons reverses impaired intracellular calcium transients in prehypertensive rats. Hypertension, 61: 202-207.
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  10. Li, D., C.W. Lee, K. Buckler, A. Parekh, N. Herring and D.J. Paterson, 2012. Abnormal intracellular calcium homeostasis in sympathetic neurons from young prehypertensive rats. Hypertension, 59: 642-649.
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  11. Herring, N., J. Cranley, M.N. Lokale, D. Li and J. Shanks et al., 2012. The cardiac sympathetic co-transmitter galanin reduces acetylcholine release and vagal bradycardia: Implications for neural control of cardiac excitability. J. Mol. Cell. Cardiol., 52: 667-676.
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  12. Adlam, D., N. Herring, G. Douglas, J.P. De Bono and D. Li et al., 2012. Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin. Cardiovascul. Res., 93: 694-701.
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  13. Wang, L., D. Li, T.A. Dawson and D.J. Paterson, 2009. Long term effect of nNOS overexpression on cardiac neurotransmission mediated by a lentiviral vector. J. Physiol., 587: 3629-3637.

  14. Li, D., J.F. Wen, J.Y. Jin, H.X. Quan and K.W. Cho, 2009. Cardiac mast cells regulate myocyte ANP release via histamine H2 receptor in beating rabbit atria. Regulat. Peptides, 155: 33-38.
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  15. Lee, C.W., D. Li, K.M. Channon and D.J. Paterson, 2009. L-arginine supplementation reduces cardiac noradrenergic neurotransmission in spontaneously hypertensive rats. J. Mol. Cell. Cardiol., 47: 149-155.
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  16. Jin, J.Y., D. Li, J.F. Wen and K.W. Cho, 2009. Increase of atrial ANP release by 2, 3-butanedione monoxime in beating rabbit atria. Regulat. Peptides, 158: 91-96.
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  17. Danson, E.J., D. Li, L. Wang, T.A. Dawson and D.J. Paterson, 2009. Targeting cardiac sympatho-vagal imbalance using gene transfer of nitric oxide synthase. J. Mol. Cell. Cardiol., 46: 482-489.
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  18. Dawson, T.A., D. Li, T.D. Woodward, Z.E. Barber, L. Wang and D.J. Paterson, 2008. Cardiac cholinergic NO-cGMP signalling following acute myocardial infarction and nNOS gene transfer. Am. J. Physiol. Heart Circ. Physiol., 295: H990-H998.
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  19. Li, D., L. Wang, C.W. Lee, T.A. Dawson and D.J. Paterson, 2007. Noradrenergic cell specific gene transfer with neuronal nitric oxide synthase reduces cardiac sympathetic neurotransmission in hypertensive rats. Hypertension, 50: 69-74.
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  20. Heaton, D.A., D. Li, S.C. Almond, T.A. Dawson and L. Wang et al., 2007. Gene transfer of nnos into intracardiac ganglia reverses vagal impairment in hypertensive rats. Hypertension, 49: 380-388.

  21. Wang, L., D. Li, C.P. Plested, T. Dawson, A.G. Teschemacher and D.J. Paterson, 2006. Noradrenergic neuron-specific overexpression of nNOS in cardiac sympathetic nerves decreases neurotransmission. J. Mol. Cell. Cardiol., 41: 364-370.
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  22. Heaton, D.A., M. Lei, D. Li, S. Golding, T.A. Dawson, R.M. Mohan and D.J. Paterson, 2006. Remodelling of cardiac pacemaker L-type calcium current and beta-adrenergic responsiveness in hypertension following nNOS gene transfer. Hypertension, 48: 443-452.

  23. Li, D., H.X. Quan, J.F. Wen, J.Y. Jin and S.H. Park et al., 2005. Ca2+-induced Ca2+ release from sarcoplasmic reticulum negatively regulates myocytic ANP release in beating rabbit atria. Korean J. Physiol. Pharmacol., 9: 87-94.
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  24. Jin, J.Y., J.F. Wen, D. Li and K.W. Cho, 2004. Osmoregulation of atrial myocytic ANP release: Osmotransduction via cross-talk between L-type Ca2+ channel and SR Ca2+ release. Am. J. Physiol.-Regulat. Integrat. Comparat. Physiol., 287: R1101-R1109.
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  25. Li, D., J.F. Wen, J.Y. Jin, H. Jin and H.S. Ann et al., 2003. Histamine inhibits atrial myocytic ANP release via H2 receptor-cAMP-protein kinase signaling. Am. J. Physiol.-Regulat. Integrat. Comparat. Physiol., 285: R380-R393.
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Member since September, 2018