Dr. Guangxing Li

Professor
Northeast Agricultural University, China


Highest Degree
Ph.D. in Veterinary Parasitology from Northeast Agricultural University, China

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Area of Interest:

Animal and Veterinary Sciences
Veterinary Pathology
Veterinary Medicine
Prophylactics
Biological Control

Selected Publications

  1. Liu, H., L. Chen, X. Wang, W. Si and H. Wang et al., 2015. Decrease of colonization in the chicks' cecum and internal organs of Salmonella enteric serovar Pullorum by deletion of cpdB by red system. Microb. Pathogenesis, 80: 21-26.
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  2. Cong, Y., X. Li, Y. Bai, X. Lv and G. Herrler et al., 2015. Porcine aminopeptidase N mediated polarized infection by porcine epidemic diarrhea virus in target cells. Virology, 478: 1-8.
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  3. Cao, L., X. Ge, Y. Gao, Y. Ren, X. Ren and G. Li, 2015. Porcine epidemic diarrhea virus infection induces NF-κB activation through the TLR2, TLR3 and TLR9 pathways in porcine intestinal epithelial cells. J. Gen. Virol., 96: 1757-1767.
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  4. Cao, L., X. Ge, Y. Gao, G. Herrler, Y. Ren, X. Ren and G. Li, 2015. Porcine epidemic diarrhea virus inhibits dsRNA-induced interferon-β production in porcine intestinal epithelial cells by blockade of the RIG-I-mediated pathway. Virol. J., Vol. 12 10.1186/s12985-015-0345-x.
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  5. Cao, L., X. Ge, Y. Gao, D.S. Zarlenga and K. Wang et al., 2015. Putative phage-display epitopes of the porcine epidemic diarrhea virus S1 protein and their anti-viral activity. Virus Genes, 51: 217-224.
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  6. Zhao, Y., X. Wang, P. Chen, X. Zeng and H. Bao et al., 2014. Detection of antibodies against avian influenza virus by protein microarray using nucleoprotein expressed in insect cells. J. Vet. Med. Sci., 77: 413-419.

  7. Si, W., S. Yu, L. Chen, X. Wang, W. Zhang, S. Liu and G. Li, 2014. Passive protection against Salmonella enteric serovar Enteritidis infection from maternally derived antibodies of hens vaccinated with a ghost vaccine. Res. Vet. Sci., 97: 191-193.
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  8. Zhu, J., Q. Yang, L. Cao, X. Dou and J. Zhao et al., 2013. Development of porcine rotavirus vp6 protein based ELISA for differentiation of this virus and other viruses. Virol. J., Vol. 10. 10.1186/1743-422X-10-91.
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  9. Yang, W., G. Li, Y. Ren, S. Suo and X. Ren, 2013. Phylogeny and expression of the nucleocapsid gene of porcine epidemic diarrhoea virus. Acta Vet. Hung., 61: 257-269.
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  10. Sun, X., Y. Ren, Y. Li, J. Zhu and W. Zhu et al., 2013. Monoclonal antibody against membrane protein of transmissible gastroenteritis virus. Monoclonal Antibodies Immunodiagn. Immunother., 32: 36-40.
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  11. Meng, F., Y. Ren, S. Suo, X. Sun and X. Li et al., 2013. Evaluation on the efficacy and immunogenicity of recombinant DNA plasmids expressing spike genes from porcine transmissible gastroenteritis virus and porcine epidemic diarrhea virus. PLoS One, Vol. 8. 10.1371/journal.pone.0057468.
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  12. Ma, D., M. Gao, J. Li, C. Ma and G. Li, 2013. Construction of novel cytokine by fusion of chicken IL-2 signal peptide to mature chicken IL-15 and comparison of the adjuvant effects by DNA immunization against Eimeria challenge. Vet. Immunol. Immunopathol., 156: 114-120.
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  13. Zhu, W., Y. Ren, G. Li, D. Su, Q. Yang and X. Ren, 2012. Antibody against porcine parvovirus VP2 protein differentiated this virus from other viruses. Pak. Vet. J., 32: 447-450.
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  14. Suo, S., Y. Ren, G. Li, D. Zarlenga and R. Bu et al., 2012. Immune Responses Induced by DNA Vaccines Bearing Spike Gene of PEDV Combined With Porcine IL-18. Virus Res., 167: 259-266.
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  15. Ma, D., C. Ma, M. Gao, G. Li, Z. Niu and X. Huang, 2012. Induction of cellular immune response by DNA vaccine coexpressing E. acervulina 3-1E gene and mature CHIL-15 gene. J. Parasitol. Res., Vol. 2012. 10.1155/2012/654279.
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  16. Li, G., Q. Hong, Y. Ren, H.S. Lillehoj, C. He and X. Ren, 2012. Development of FPV140 antigen-specific ELISA differentiating fowlpox virus isolates from all other viral pathogens of avian origin. Poult. Sci., 91: 2507-2511.
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  17. Gao, M., J. Cui, Y. Ren, S. Suo and G. Li et al., 2012. Development and evaluation of a novel reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay for detection of type II porcine reproductive and respiratory syndrome virus. J. Virol. Methods, 185: 18-23.
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  18. Dai, C., J. Li, W. Lin, G. Li, M. Sun, F. Wang and J. Li, 2012. Electrophysiology and ultrastructural changes in mouse sciatic nerve associated with colistin sulfate exposure. Toxicol. Mechanisms Methods, 22: 592-596.
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  19. Cui, J., X. Wang, Y. Ren, S. Cui, G. Li and X. Ren, 2012. Genome sequence of chinese porcine parvovirus strain PPV2010. J. Virol., 86: 2379-2379.
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  20. Yin, J., G. Li, J. Li, Q. Yang and X. Ren, 2011. In Vitro and In Vivo Effects of Houttuynia cordata on Infectious Bronchitis Virus. Avian Pathol., 40: 491-498.
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  21. Wu, D., G. Li, C. Qin and X. Ren, 2011. Phage displayed peptides to avian H5N1 virus distinguished the virus from other viruses. PLoS One, Vol. 6. 10.1371/journal.pone.0023058.
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  22. Wang, X., G. Li, Y. Ren and X. Ren, 2011. Phages bearing affinity peptides to bovine rotavirus differentiate the virus from other viruses. PLoS One, Vol. 6. 10.1371/journal.pone.0028667.
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  23. Ren, X., J. Yin, G. Li and G. Herrler, 2011. Cholesterol Dependence of Pseudorabies Herpesvirus Entry. Curr. Microbiol., 62: 261-266.
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  24. Ren, X., G. Li and X. Sui, 2011. Antiviral activities of phosphonoformate sodium to pseudorabies herpesvirus Infection In Vitro. Pharm. Biol., 49: 608-613.
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  25. Ren, X., F. Meng, J. Yin, G. Li, X. Li, C. Wang and G. Herrler, 2011. Action mechanisms of lithium chloride on cell infection by transmissible gastroenteritis coronavirus. PloS One, Vol. 6. .
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  26. Ren, X., B. Liu, J. Yin, H. Zhang and G. Li, 2011. Phage displayed peptides recognizing porcine aminopeptidase N inhibit transmissible gastroenteritis coronavirus infection in vitro. Virology, 410: 299-306.
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  27. Meng, F., Z. Zhao, G. Li, S. Suo and N. Shi et al., 2011. Bacterial expression of antigenic sites A and D in the spike protein of transmissible gastroenteritis virus and evaluation of their inhibitory effects on viral infection. Virus Genes, 43: 335-341.
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  28. Ma, D., C. Ma, L. Pan, G. Li and J. Yang et al., 2011. Vaccination of chickens with DNA vaccine encoding Eimeria acervulina 3-1E and chicken IL-15 offers protection against homologous challenge. Exp. Parasitol., 127: 208-214.
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  29. Liu, Q., B. Kong, G. Li, N. Liu and X. Xia, 2011. Hepatoprotective and antioxidant effects of porcine plasma protein hydrolysates on carbon tetrachloride-induced liver damage in rats. Food Chem. Toxicol., 49: 1316-1321.
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  30. Li, G., N. Shi, S. Suo, J. Cui, D. Zarlenga and X. Ren, 2011. Vaccination of mice with ORF5 plasmid DNA of PRRSV, enhanced effects by co-immunizing with porcine IL-15. Immunol. Invest., 41: 231-248.
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  31. Li, G. and X. Ren, 2011. Differentiation of Porcine Reproductive and Respiratory Syndrome Virus N Protein Using a Virus-based ELISA. Hybridoma, 30: 195-198.
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  32. Lee, K.W., H.S. Lillehoj, S.I. Jang, G.X. Li and D.A. Bautista et al., 2011. Effects of coccidiosis control programs on antibody levels against selected pathogens and serum nitric oxide levels in broiler chickens. J. Applied Poult. Res., 20: 143-152.
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  33. Lee, K.W., H.S. Lillehoj, G. Li, M.S. Park and S.I. Jang et al., 2011. Identification and cloning of two immunogenic Clostridium perfringens proteins, elongation factor Tu (EF-Tu) and Pyruvate: Ferredoxin Oxidoreductase (PFO) of Clostridium perfringens. Res. Vet. Sci., 91: e80-e86.
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  34. Lee, K.W., G. Li, H.S. Lillehoj, S.H. Lee and S.I. Jang et al., 2011. Bacillus subtilis-based direct-fed microbials augment macrophage function in broiler chickens. Res. Vet. Sci., 91: e87-e91.
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  35. Dong, X., G.H. Abdelnabi, S.H. Lee, G. Li, H. Jin, H.S. Lillehoj and X. Suo, 2011. Enhanced egress of intracellular Eimeria tenella sporozoites by splenic lymphocytes from coccidian-infected chickens. Infect. Immun., 79: 3465-3470.
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  36. Ding, F., D.S. Zarlenga, Y. Ren, G. Li, J. Luan and X. Ren, 2011. Use of the DR model to define trends in the emergence of Ceftazidime-resistant Escherichia coli in China. PLoS One, Vol. 6. 10.1371/journal.pone.0027295.
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  37. Zhang, H., G. Li and X. Ren, 2010. Expression, antibody generation and biological analysis of chicken interleukin-18. Hybridoma, 29: 525-529.
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  38. Shao, M., Y. Wang, C. Wang, Y. Guo and Y. Peng et al., 2010. Evaluation of multicomponent recombinant vaccines against Actinobacillus pleuropneumoniae in mice. Acta Vet. Scand., Vol. 52. 10.1186/1751-0147-52-52.
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  39. Ren, X., M. Wang, J. Yin, Y. Ren and G. Li, 2010. Heterologous Expression of Fused Genes Encoding the Glycoprotein 5 from PRRSV: A Way for Producing Functional Protein in Prokaryotic Microorganism. J. Biotechnol., 147: 130-135.
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  40. Ren, X., M. Wang, J. Yin and G. Li, 2010. Phages Harboring Specific Peptides That Recognize the N Protein of the Porcine Reproductive and Respiratory Syndrome Virus Distinguish the Virus from Other Viruses. J. Clin. Microbiol., 48: 1875-1881.
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  41. Ren, X., G. Li and B. Liu, 2010. Binding Characterization of Determinants in Porcine Aminopeptidase N, the Cellular Receptor for Transmissible Gastroenteritis Virus. J. Biotechnol., 150: 202-206.
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  42. Meng, F., J. Yin, X. Li, W. Yang and G. Li et al., 2010. Production and Characterization of a Monoclonal Antibody Against Spike Protein of Transmissible Gastroenteritis Virus. Hybridoma, 29: 345-350.
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  43. Li, G., Y. Zeng, J. Yin, H.S. Lillehoj and X. Ren, 2010. Cloning, prokaryotic expression and biological analysis of recombinant chicken IFN-γ. Hybridoma, 29: 1-6.
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  44. Li, G., J. Hong, X. Ren, J. Yin, S. Feng and G. Huo, 2010. Prokaryotic expression of Stx1B subunit of Escherichia coli O157: H7 used to generate monoclonal antibody. Hybridoma, 29: 283-289.
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  45. Li, G., J. Hong, G. Huo and X. Ren, 2010. Monoclonal Antibodies Against Stx1B Subunit of Escherichia coli O157:H7 Distinguish the Bacterium from Other Bacteria. Lett. Appl. Microbiol., 51: 499-503.
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  46. Li, G., H.S. Lillehoj, K.W. Lee, S.I. Jang and P. Marc et al., 2010. An outbreak of gangrenous dermatitis in commercial broiler chickens. Avian Pathol., 39: 247-253.
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  47. Li, G., H.S. Lillehoj, K.W. Lee, S.H. Lee and M.S. Park et al., 2010. Immunopathology and cytokine responses in commercial broiler chickens with gangrenous dermatitis. Avian Pathol., 39: 255-264.
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  48. Lee, K.W., S.H. Lee, H.S. Lillehoj, G.X. Li and S.I. Jang et al., 2010. Effects of direct-fed microbials on growth performance, gut morphometry and immune characteristics in broiler chickens. Poult. Sci., 89: 203-216.
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  49. Lee, K.W., H.S. Lillehoj, S.I. Jang, G.X. Li, S.H. Lee, E.P. Lillehoj and G.R. Siragusa, 2010. Effect of Bacillus-based direct-fed microbials on Eimeria maxima infection in broiler chickens. Compa. Immunol. Microbiol. Infect. Dis., 33: e105-e110.
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  50. Yin, J., G. Li, X. Ren and G. Herrler, 2007. Select what you need: A comparative evaluation of the advantages and limitations of frequently used expression systems for foreign genes. J. Biotechnol., 127: 335-347.
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  51. Ren, X., J. Yin and G. Li, 2007. Targeting the chromosome integration sites of HIV in host cells-A proposal for understanding and preventing AIDS. Med. Hypotheses, 4: 952-953.
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  52. Li, G., J. Yin and X. Ren, 2007. Analysis of the Potential of Retroviral Gene Vectors Produced on Yeast Intracellular Membranes. Med. Hypotheses, 68: 463-464.
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  53. Yin, J.C., G.X. Li, Y.J. Li and X.F. Ren, 2006. A point mutation of S gene from TGEV isolate TH-98 followed construction of shuttle plasmid used in E. coli/yeast expression system. J. Am. Sci., 2: 83-88.
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  54. Yin, J., G. Li and X. Ren, 2006. An overview of veterinary medical education in China: Current status, deficiencies and strategy for improvement. J. Vet. Med. Educ., 33: 238-243.
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  55. Ren, X., J. Yin and G. Li, 2006. Cell Apoptosis should be Negative in Viral Infection. Med. Hypotheses, 67: 675-676.
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  56. Li, G., J. Yin, Y. Ren, B. Wang and X. Ren, 2006. A descriptive analysis of computer-assisted teaching and learning in molecular biological education. Biochem. Mol. Biol. Educ., 34: 272-274.
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  57. Li, G., J. Yin and X. Ren, 2006. Could a Genetic Engineering Created Virus be A Competitor to HIV for CD4 Receptors? Med. Hypotheses, 67: 1473-1474.
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  58. Lillehoj, H.S. and G. Li, 2004. Nitric oxide production by macrophages stimulated with coccidia sporozoites, lipopolysaccharide, or interferon-γ and its dynamic changes in SC and TK strains of chickens infected with Eimeria tenella. Avian Dis., 48: 244-253.
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  59. Min, W., H.S. Lillehoj, G. Li, E.J. Sohn and T. Miyamoto, 2002. Development and characterization of monoclonal antibodies to chicken interleukin-15. Vet. Immunol. Immunopathol., 88: 49-56.
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  60. Li, G., E.P. Lillehoj and H.S. Lillehoj, 2002. Interleukin-2 production in SC and TK chickens infected with Eimeria tenella. Avian Dis., 46: 2-9.
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  61. Li, G., H.S. Lillehoj and W. Min, 2001. Production and characterization of monoclonal antibodies reactive with the chicken interleukin-15 receptor alpha chain. Vet. Immunol. Immunopathol., 82: 21-227.
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